惠农县农村中小学生常见病调查分析

为了解中小学生常见病的发病状况,采用分层整群抽样方法,对惠农县中小学生４５４７名进行了调查。结果惠农县中小学生常见病患病率仍高于自治区平均水平,其中营养不良患病率２５．３４％,视力低下患病率９．３７％,龋齿患病率２１．７３％。应对中小学生加强实施健康教育知识干预,培养学生良好的学习及生活习惯。     

三亚市中小学生健康体检结果分析

目的了解三亚市中小学生常见病患病情况，为防治工作提供科学依据。方法对2004年监测点校学生健康体检资料共14751人份进行统计分析。结果视力低下率为22．62％。女生明显高于男生，中学生明显高于小学生，市区中小学生明显高于乡镇中小学生；龋齿患病率为42．89％，女生明显高于男生，小学生明显高于中学生，市区中小学生明显高于乡镇中小学生；沙眼患病率为1．80％，乡镇小学生沙眼发病率最低，为0．36％；营养不良患病率为39．49％，女生明显高于男生，中学生明显高于小学生，乡镇中学生明显高于市区中学生，市区小学女生明显高于乡镇小学女生（P〈0．05）；营养过剩患病率为7．73％，男女生之间差异无显著性，小学生明显高于中学生，市区学生明显高于乡镇学生。结论三亚市中小学生沙眼患病率已控制在3．00％以下，已达到国家的第二阶段防治目标；视力低下、龋齿患病情况较严重，应加强防治工作；营养不良和营养过剩患病率处于较高水平，学生营养状况不容乐观，应引起有关部门的重视。     

宁夏永宁县2012年中小学生健康体检结果分析

目的了解永宁县中小学生生长发育状况及学生常见病患病情况。方法按照《中小学生健康体检管理办法》,对2012年永宁县38所中小学22952名学生进行健康体检,并分析评价学生发育水平及健康状况。结果22952名中小学生中视力不良检出率55．48％,龋齿检出率9．45％,营养不良检出率16．57％,身高偏低检出率14．24％,体重偏低检出率11．20％,超重检出率6．06％,沙眼、生理弯曲、色盲等,检出率分别为4．64％、0．35％、0．84％。结论永宁县中小学生视力不良、营养不良、较低身高、体重、龋齿的检出率较高,应进一步加强学生常见病防治工作,大力开展视力保健、膳食营养知识的健康教育。     

深圳市宝安区中小学生视力普查情况及分析

为了能更好的开展中小学生近视防治工作及改善宝安区中小学学校教学设施条件,我们汇总2006～2007年宝安区中小学学生的视力调查状况并分析结果,了解中小学生视力不良患病率,为以后的视力不良防治工作和改善学校学习环境提供数据依据。     

东潍煤矿中小学生3种疾病监测分析

目的 为了解东潍煤矿中小学生常见病发病情况,以便制订防治措施。方法 对矿子弟学校２５９８名学生进行视力不良、龄齿、沙眼发病率调查,统计分析不同年龄、性别、年级之间的差异。结果 视力不良患病率为３２．４％,患龋率为２９．８％,沙眼患病率１０．２％,视力不良为女性（４０．８％）大于男性（２４．９％）,并随着学年的增加而增加,龄齿为小年龄组多见（小学４０．９％）,中学（１３．７％）沙眼为男性（１２．５％     

山西省中小学生营养状况调查分析

目的：了解山西省中小学生营养状况，以便科学地指导学生保健工作。方法：按有关标准对1999年至2003年间11个市(地)监测点在校的3651554名中小学生进行身高、体重测量，并评价其营养状况。结果：营养不良率在6．69％～7．31％之间，平均检出率为6．89％；肥胖率在4．59％～5．68％之间，平均检出率为4．95％。营养不良率和肥胖率均为城市高于县镇、中学高于小学。结论：山西省预防控制学生营养不良、肥胖的重点应是城市学生和中学生。     

东滩煤矿中小学生3种疾病监测分析

为了解东滩煤矿中小学生常见病发病情况 ,以便制订防治措施。方法　对矿子弟学校 2 5 98名学生进行视力不良、龋齿、沙眼发病率调查 ,统计分析不同年龄、性别、年级之间的差异。结果　视力不良患病率为 32 .4% ,患龋率为 2 9.8% ,沙眼患病率 10 .2 % ,视力不良为女性 (4 0 .8% )大于男性 (2 4.9% ) ,并随着学年的增加而增加 ,龋齿为小年龄组多见 (小学 40 .9% ) ,中学 13.7% ) ,沙眼为男性 (12 .5 % )大于女性 (7.6 % )。结论　视力不良和龋齿的发病较严重 ,高于国内许多学者的调查结果 ,建议应加强学生对该 3种疾病的防治工作     

汉源县中小学生体质健康状况调查分析

目的：了解汉源县中小学生体质健康状况。方法：抽样调查汉源县1994名中小学生中视力低下、龋齿、营养不良和肥胖情况。结果：视力低下率43．6％、龋患率20．8％、营养不良率12．6％和肥胖率8．3％。结论：为提高中小学生体质健康水平,教育和卫生部门应联合采取综合方案,特别是加强身体锻炼和卫生保健知识教育。     

白芨沟矿育新学校中小学生生长发育及常见病患病情况分析

目的 了解白芨沟矿育新学校中小学生生长发育及三种常见病患病情况。方法 身高、体重等级评价以百分位数法为标准。裸眼视力低于5．0者为视力低下；沙眼诊断以眼科学为标准；龋齿诊断以《口腔健康调查方法》为标准。结果 中小学生身高、体重在上、中、下等中以中等所占比重最高，三种常见病以视力低下患病率最高，其次为龋齿率，最低为沙眼患病率。结论 中小学生身高、体重、发育属中等水平，中学生视力低下率最高，小学生龋患率最高，应做好学生视力保护和口腔卫生保健工作。     

入托儿童生长发育状况分析

目的：为对集体儿童保健工作的开展进行有针对性的指导，保证儿童入托后健康成长。方法：2007年1～8月在我院入托体检的677例儿童生长发育状况进行分析评价。结果：儿童超重和肥胖检出率分别为5．2％和3．5％；营养不良患病率为3．1％；儿童视力不良检出率为23．1％；儿童患龋率随年龄的增长而增加，3岁左右龋病率上升较快。结论：我们应重视儿童的健康问题，加强儿童保健指导，积极开展健康宣教，对于儿童存在的健康问题应及早进行干预治疗。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Electro-Acupuncture Combined with the Trigger Point Needle-Embedding for Treatment of Primary Trigeminal Neuralgia in 31 Cases

In recent years, the author of this essay has applied electro-acupuncture combined with the trigger point needle-embedding for treatment of primary trigeminal neuralgia in 31 cases, yielding satis- factory results as reported in the following.     

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Objective： To explore the role of matrix metalloproteinase-1,2 （MMP-1, MMP-2） and tissue inhibitor of matrix metalloproteinases-1 （TIMP-1） in endometriosis. Methods： The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.endometria from 40 subjects （excluding endometriosis） were collected and examined by in situ hybridization technology and western blot assay. Results： Both expressions of MMP-1 and -2 were stronger in ectopic endometrium and eutopic endometrium than in normal endometrium. On the contrary, the expression of TIMP-1 in ectopic endometrium and eutopic endometrium was lower. The differences were significant （P 〈 0.01 ）. Moreover, there was no relationship among the expressions of MMP-1, 2 and TIMP-1 in ectopic endometrium. Conclusion： The expressions of MMP-1, 2 and TIMP-1 lose balance and lack of periodic changes in ectopic endometrium , which explains the biological invasive behavior of endometriosis. It was suggested-that regulating the balance between the MMPs and TIMP-1 should be an ideal therapeutic target to endometriosis.     

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Prof. SHI Da-zhuo, Ph.D., male, was born on March 20, 1960. Prof. SHI entered the Ph.D. program in 1990 at the China Academy of Chinese Medical Sciences under the supervision of Prof. CHEN Ke-ji, majoring in the treatment of cardiovascular diseases. After receiving his Ph.D. degree in 1993, Prof. SHI started working at the Cardiovascular Center in Xiyuan Hospital affiliated to China Academy of Chinese Medical sciences.     

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.