An Improved Vaginal Cream in the Practice of Gynecology

Important eye symptoms in diagnosis of eye conditions having general causes are discussed. Eye lesions in diseases of the kidney, thyroid gland and blood vessels and infections are described. A closer alliance between the general physician and specialist with particular emphasis on the early diagnosis of glaucoma is stressed in the interest of preventing unnecessary blindness.     

他克莫司乳膏对皮炎湿疹患者免疫功能及血清炎性因子水平的影响观察

目的观察他克莫司乳膏对皮炎湿疹患者免疫功能及血清炎性因子水平的影响。方法选取我院收治的114例皮炎湿疹患者,随机分为观察组和对照组各57例。观察组采取他克莫司乳膏治疗,对照组采取涂抹丁酸氢化可的松治疗,比较两组患者治疗前后免疫功能及血清炎性因子水平。结果观察组患者治疗后CD3+、CD4+水平均高于治疗前,CD8+水平低于治疗前,差异有统计学意义(P0.05)。对照组患者治疗后CD3+水平高于治疗前,差异有统计学意义(P0.05)。观察组患者CD3+、CD4+水平均高于对照组,CD8+水平低于对照组,差异有统计学意义(P0.05)。观察组患者IL-4、IFN-γ、IL-10水平均低于对照组,差异均有统计学意义(P0.05)。结论他克莫司软膏可改善了患者免疫功能和血清炎性因子水平,是治疗皮炎湿疹的有效药物,临床价值较高。     

多磺酸黏多糖乳膏联合半导体激光治疗面部糖皮质激素依赖性皮炎的临床观察

目的对多磺酸黏多糖乳膏(商品名喜辽妥)联合半导体激光治疗面部糖皮质激素依赖性皮炎(以下简称:激素依赖性皮炎)的临床疗效进行分析。方法将我院收治的242例经门诊检测确诊为激素依赖性皮炎的患者随机分为两组,观察组121例采用多磺酸黏多糖乳膏联合半导体激光治疗;对照组121例采用尿素乳膏治疗。结果经过10d治疗,观察组患者治疗效果明显优于对照组患者。结论多磺酸黏多糖乳膏联合半导体激光治疗激素依赖性皮炎效果满意,适合在临床中广泛推广运用。     

An Alternative Approach to Atopic Dermatitis: Part I-Case-Series Presentation

Atopic dermatitis (AD) is a complex disease of obscure pathogenesis.A substantial portion of AD patients treated with conventionaltherapy become intractable after several cycles of recurrence.Over the last 20 years we have developed an alternative approachto treat many of these patients by diet and Kampo herbal medicine.However, as our approach is highly individualized and the Kampoformulae sometimes complicated, it is not easy to provide evidenceto establish usefulness of this approach. In this Review, todemonstrate the effectiveness of the method of individualizedKampo therapy, results are presented for a series of patientswho had failed with conventional therapy but were treated afterwardsin our institution. Based on these data, we contend that thereexist a definite subgroup of AD patients in whom conventionaltherapy fails, but the ‘Diet and Kampo’ approachsucceeds, to heal. Therefore, this approach should be consideredseriously as a second-line treatment for AD patients. In theDiscussion, we review the evidential status of the current conventionalstrategies for AD treatment in general, and then specificallydiscuss the possibility of integrating Kampo regimens into it,taking our case-series presented here as evidential basis. Weemphasize that Kampo therapy for AD is more ‘art’than technology, for which expertise is an essential pre-requisite.     

恩纳乳膏在静脉穿刺中的应用

20 0 1年 4月— 2 0 0 1年 6月 ,我室应用恩纳 (ＥＭＬＡ)乳膏作为皮肤表面麻醉剂 ,应用于静脉穿刺 ,以解决静脉穿刺时疼痛。现将临床应用情况总结如下。1　临床资料1.1　一般资料　本组肿瘤病人 34例 ,为美国麻醉学家协会(ＡＳＡ)Ⅰ级～Ⅱ级 ,男 18例 ,女 16例 ,年龄最小 13岁 ,最大 79岁 ,均为肿瘤病人 ,其中胸科 7例 ,骨科 3例 ,妇科 3例 ,普外科 6例 ,头颈科 10例 ,肛肠科 5例。1.2　应用方法　术前 1ｄ阅读病历 ,检查病人 ,向病人说明皮肤表面麻醉剂作用和应用方法 ,争取其合作 ,并将准备贴敷部位作好标记。术前 1ｈ贴敷恩纳乳膏 ,用量…     

An Alternative Approach to Atopic Dermatitis: Part II-Summary of Cases and Discussion

In the first part of this Review, we presented case-series whereKampo treatment was introduced for those atopic dermatitis (AD)patients who had failed with conventional therapy, in an attemptto prove that there exists a definite subgroup of AD patientsfor whom Kampo treatment is effective. In this second part,we will first provide the summary of the results for 140 ADpatients we treated in 2000. The results suggest that Kampotreatment is effective for more than half of AD patients whofail with conventional therapy. In the Discussion, we will examinethe evidential basis for conventional AD therapy and discusshow Kampo treatment should be integrated into the guidelinesfor AD therapy. We contend that Kampo treatment should be triedbefore systematic immunosuppressive agents are considered. Aseach Kampo treatment is highly individualized, it should beregarded more as ‘art’ than technology, and specialcare should be taken to assess its efficacy in clinical trial.     

An evaluation of lecturer practitioners in Ireland

Nursing continues to struggle to integrate the theoretical and clinical aspects of nurse education for the development of competent practitioners. Collaborative approaches to nurse education as well as the development of joint clinical-academic roles have had questionable success to date on merging the theoretical and clinical components of nursing. Lecturer practitioners' posts are new in Ireland. These posts were created as nurse educators were cognizant of the need for students to integrate theory to practice. The aim of the lecturer practitioner role was to increase the support forstudent nurses in both academia and practice. An evaluation of the impact of the lecturer practitioner role from three key perspectives was conducted in three Irish teaching hospitals in 2007. The results of this study suggest that as lecturer practitioners have both a clinical and academic remit they can integrate theory to practice through collaborative practice.     

An overview of evaluation research in nursing

This paper attempts to explain some general issues in evaluation and evaluative research in the health care field with specific reference to nursing. The evaluation process and nursing process are contrasted and methods used in evaluative research discussed. The case is made for more emphasis to be placed on the evaluation phase of the nursing process and process-outcome evaluation is advocated as a means of encouraging progress in the hitherto neglected area of evaluative research in nursing.     

An evaluation of multi-professional education in diabetes

The role of multi-professional learning in diabetes care has been controversial due largely to the severe practical problems that need to be overcome to allow comparisons with the standard uni-disciplinary approach. We describe the operation and analysis of a unique university-based but community-orientated multi-professional diabetes care course over a four-year period. The analysis is based both on objective assessment of students by the teaching team and by the assessment of the course and the teaching methodology by the students following completion. The results show significant improvements in knowledge, very good perception of quality and usefulness, with a large impact on the students' clinical confidence and perceived clinical practice following completion. Analysis in nine areas of diabetic care is presented with the vast majority of responding students confirming a better community standard of care as a result. We are of the opinion that these results support the application of multi-professional learning to encourage improved community care of diabetes.     

An evaluation of multi-professional education in diabetes

The role of multi-professional learning in diabetes care has been controversial due largely to the severe practical problems that need to be overcome to allow comparisons with the standard uni-disciplinary approach. We describe the operation and analysis of a unique university-based but community-orientated multi-professional diabetes care course over a four-year period. The analysis is based both on objective assessment of students by the teaching team and by the assessment of the course and the teaching methodology by the students following completion. The results show significant improvements in knowledge, very good perception of quality and usefulness, with a large impact on the students' clinical confidence and perceived clinical practice following completion. Analysis in nine areas of diabetic care is presented with the vast majority of responding students confirming a better community standard of care as a result. We are of the opinion that these results support the application of multi-professional learning to encourage improved community care of diabetes.     

Transdermal Kinetics of A Mercurous Chloride Beauty Cream: An In Vitro Human Skin Analysis

Background: Crema de Belleza-Manning is a popular mercurous chloride-containing beauty cream used to smooth and lighten the complexion and treat acne. Hundreds of people in the Southwestern US border states have been identified with elevated (>20 μg/L) urine mercury levels believed to be secondary to using this cream. The kinetic characteristics of percutaneous mercury absorption are incompletely defined. The objective of this study was to determine the transdermal kinetics of two formulations of mercurous chloride from a beauty cream in an in vitro human skin model. Methods: A proprietary formulation and an aqueous formulation of the beauty cream were studied using modified Franz diffusion cells. Mercury content in the skin samples and the underlying diffusion buffer was determined using atomic absorption spectrophotometry. Results: A rapid initial increase in mercury content both in the skin and the buffer was noted for both formulations. Mercury concentrations in the aqueous samples were significantly (p < 0.05) higher in both the skin and the diffusion buffer compared to parallel samples containing glycerol. Conclusions: Mercury was readily absorbed through the skin in this in vitro human skin model. The aqueous preparation had a markedly increased rate and extent of mercury absorption relative to the proprietary formulation.     

An evaluation of non-verbal handover

Verbal handover can have a detrimental effect on nursing documentation. Information provided by verbal handover can be retrospective and task-orientated. Non-verbal handover can save time and ensure documentation is properly updated.