共查询到19条相似文献,搜索用时 46 毫秒
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皮肤混合瘤1例 总被引:1,自引:1,他引:0
皮肤混合瘤又名软骨样汗管瘤,是一种类似涎腺混合瘤的罕见的汗腺良性肿瘤。笔者诊治1例上唇皮肤混合瘤,现报告如下。患者男,59岁。因左口角上方无痛性肿块3年,近期出现肿痛,于2004年6月至我科就诊。肿块初起时约米粒大,生长缓慢,因无不适,一直未就诊。皮肤科检查:左口角上方一2cm×1.5cm×0.8cm隆起性肿块,皮损表面呈淡红色(图1A)。质硬,界限清。于局麻下将肿块组织切除后送检,组织病理检查示:瘤细胞呈片状、条索状、管状及囊腔状结构(图1B),管腔大小不等,形状不一,管腔和囊腔覆以两层细胞,腔面为立方形细胞,外层为扁平细胞,上述结构分散在… 相似文献
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例1女,40岁,鼻尖部无痛性肿物2年;例2女,36岁,鼻尖下方无痛性肿物3年。2例均表现为鼻尖部皮下结节,淡红色,表面光滑,边界清楚,中等硬度,无压痛。皮肤组织病理检查均支持"皮肤混合瘤"的诊断。 相似文献
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Zirbs M Konstantinow A Ziai M Brockow K Hein R Ring J 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》2011,62(9):688-690
An 81-year-old woman presented with a skin-colored, slowly growing tumor on her right lower eyelid. The diagnosis of mixed tumor of the skin was confirmed after excision and histologic examination of the tissue, which demonstrated a characteristic histology and immunohistochemistry. The mixed tumor of the skin is a usually benign neoplasm believed to originate in sweat glands. It is composed of epithelial cells set in a mesenchymal matrix, showing apocrine differentiation. Immunohistochemical staining is positive for cytokeratin, CEA, EMA and S100. 相似文献
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对我院2008年至2020年6月12例皮肤混合瘤患者资料进行回顾性分析。12例患者中男7例,女5例,发病年龄为22~77岁。12例均发生于面部 (上唇部最多见),其中11例表现为单发无自觉症状的淡红色或肤色坚韧肿物,1例因外界因素出现破溃。组织病理示9例向大汗腺分化,3例向小汗腺分化。12例患者中,临床诊断为皮肤混合瘤仅1例,诊断为皮肤纤维瘤和表皮样囊肿的各3例,诊断为钙化上皮瘤、附属器肿瘤和皮角各1例,皮疹待查2例。12例患者均行手术切除,随访2个月~6年,均无复发。 相似文献
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Mixed tumor of the skin: a model of divergent differentiation 总被引:1,自引:0,他引:1
S. E. Mills 《Journal of cutaneous pathology》1984,11(5):382-386
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例1 男,65岁,因面部结节3个月,于2011年9月18日来我科就诊.3个月前无明显诱因,于左侧鼻唇沟下方发现1个结节,无痛痒,未出现破溃现象.家族中无类似发病史.体检:一般情况好,各系统检查无明显异常.皮肤科检查:左侧鼻唇沟下方可见一单发结节,绿豆大小,肤色,质硬,无压痛,表面光滑无破溃,可见粟粒大小乳白色透明结节(图1).皮损组织病理检查:表皮大致正常.真皮内可见肿瘤团块,界限清楚,有假包膜,肿瘤由上皮和间质构成,上皮细胞呈条索状或团块状,可见导管分化,导管由两层细胞组成,内层细胞胞质淡染,核卵圆形.外层肌上皮细胞胞质淡染,核梭形.间质内淡蓝色黏液样物质(图2).诊断:皮肤混合瘤. 相似文献
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Biernat W 《The American Journal of dermatopathology》2008,30(3):284-286
An unusual tumor of the neck in a 56-year-old female is reported. The tumor was composed of tubules and small cords of epithelial cells dispersed in the fibromyxoid and adipose stroma. At the periphery, the tumor was not encapsulated and its border was intermingled with the subcutaneous fat. Lack of decapitation secretion and the absence of long tubules suggested an eccrine origin; however, in some of the tumor areas, the cells showed brightly eosinophilic copious cytoplasm that may indicate an apocrine differentiation. As an area of chondroid metaplasia was identified, the diagnosis of a mixed tumor was rendered. This unusual type of skin adnexal neoplasm with unique relation of the epithelial component to the surrounding adipose tissue requires differentiation with the primary cutaneous and metastatic carcinomas. 相似文献
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S E Cowper T Kilpatrick S Proper M B Morgan 《The American Journal of dermatopathology》1999,21(3):213-219
Solitary fibrous tumor (SFT) is an uncommon mesenchymal tumor that typically arises in the pleural cavity. Comprised of spindled cells characteristically arranged in diverse architectural patterns, SFT histologically simulates a variety of benign and malignant mesenchymal tumors. The diagnosis of SFT has been refined by the availability of newer immunohistochemical markers such as CD-34 and factor XIIIa, facilitating the identification of SFTs arising in multiple extrapleural sites, including the skin. We describe three cases of primary cutaneous SFT, review the literature, and discuss the histologic and immunohistochemical differential of other cutaneous tumors that SFT can mimic. 相似文献