共查询到17条相似文献,搜索用时 62 毫秒
1.
线状和漩涡状痣样过度黑素沉着病 总被引:1,自引:1,他引:0
报告1例线状和漩涡状痣样过度黑素沉着病。患者女,17岁。出生2周后周身即出现色素斑,并排列成条纹状或漩涡状,皮损面积广泛,无黏膜、眼睛、掌跖受累,损害至成年仍未消退。组织病理学检查示基底层色素增加和黑素细胞增多,无色素失禁。本病易与色素失禁症和早期线状表皮痣相混淆。 相似文献
2.
《皮肤性病诊疗学杂志》2015,(5):397-398
报告线状和漩涡状痣样过度黑素沉着病1例。患者,男,1岁6个月,出生4月后双小腿出现大小不一的褐色斑,逐渐向上蔓延至躯干、上肢及头面部,皮损分布广泛,呈线状和漩涡状,无掌跖、黏膜、眼睛受累。皮肤组织病理:表皮角化过度,乳头瘤样增生,基层色素增多;真皮浅层血管周围少许淋巴组织细胞。 相似文献
3.
4.
患者女,15岁. 主诉:因躯干、四肢出现色素沉着斑15年,于2006年4月就诊. 现病史:患者出生1个月后胸部、腹部出现黑褐色斑.色素斑随着年龄增长逐渐增多、扩大,呈线状、条索状或漩涡状.色素斑发生前皮肤无红斑、水疱和瘙痒.患者曾多次在当地医院就诊,被诊断为色素失禁症,未接受任何治疗. 相似文献
5.
病例资料患儿,男,5个月。因全身淡褐色色素沉着斑5个月,于2015年7月7日来我院就诊。患儿出生后全身出现淡褐色色素沉着斑,色素斑随患儿发育渐增多、扩大为线状、条索状和旋涡状。色素斑出现前皮肤未见红斑、水疱、脓疱等;不发热,无痒痛症状;饮食及大小便无异常。患儿第一胎,足月顺产;父母体健,家族中无类似皮肤病史。体格检查:一般情况可,系统检查无异常。 相似文献
6.
患儿女,5月龄,因全身散在不规则褐色色素沉着4个月,于2010年9月15日就诊,患儿出生后1个月无明确诱因在躯干和头面部、四肢等处同时出现散在轻微褐色点状斑疹,未处水疱,在外院疑诊为湿疹, 相似文献
7.
患者,男,15岁。因全身出现线状、漩涡状色素沉着15年就诊。出生时左侧臀部可见局部突起,学步时发现跛行。X线检查示:右下肢较对侧缩短。诊断为线状和痣样过度黑素沉着病合并骨骼异常。 相似文献
8.
报告1 例婴儿线状和漩涡状痣样过度黑素沉着病。患者女, 5月。出生4 周后周身即出现色素斑, 并排列成条纹状或漩涡状, 皮损面积广泛, 无黏膜、眼睛、掌跖受累, 生长发育无异常。组织病理学检查示基底层色素增加和黑素细胞增多, 无色素失禁。本病常被误诊为色素失禁症。 相似文献
9.
患者男,29岁.因全身皮肤色素沉着斑29年,于2008年3月来本院就诊.患者出生2周后,背部,四肢和面部出现褐色斑点,色斑发生前皮肤无红斑、水疱和瘙痒,色斑随年龄增大而逐渐增多扩大,并排列成条纹状或漩涡状,无自觉症状.发育以及智力均正常,各系统检查未见异常,父母健康,非近亲结婚,家族中无类似疾病患者. 相似文献
10.
线状和漩涡状痣样过度黑素沉着病是一种以沿Blaschko线分布的色素沉着为特征的遗传性皮肤病,现将我们所见1例报道如下. 临床资料患者男,24岁.因躯干、四肢出现色素沉着24年就诊.患者出生时背中部即存在线状淡褐色色素沉着斑,未出现水疱、丘疹.4岁时开始出现皮损颜色加深,范围逐渐扩展至躯干四肢,部分形成漩涡状,双下肢内侧出现线状分布深褐色色素沉着.患者既往体健,智力正常,无其他遗传性疾病史.父母非近亲结婚,其他家族成员中未见类似疾病. 相似文献
11.
Linear and whorled nevoid hypermelanosis (LWNHM) is a reticulate pigmentary disorder with a sporadic occurrence, representing genetic mosaicism. It is characterised by hyperpigmented macules in a reticulate pattern along Blaschko's lines, sparing the mucous membranes and stabilising after one to two years. It may be associated with various neurological abnormalities. The disorder may resemble incontinentia pigmenti, epidermal nevus, or zebra-like hyperpigmentation clinically. We report LWMNHM in a 15-year-old girl with progressively increasing streaks of reticulate hyperpigmented macules arranged in a whorled pattern over the trunk and extremities, which appeared soon after birth. There was no history of any preceding eruption or any associated systemic abnormality. Histopathological examination revealed basal cell hyperpigmentation without any pigmentary incontinence. CT scan of the brain was normal. 相似文献
12.
We report a 17-year-old girl who presented with linear and whorled melanosis following Blaschko lines mainly on her trunk. Ichthyosiform lesions and linear scaling erythemas were observed respectively on her lower limbs and the dorsa of her hands, left knee, ankle and foot. No abnormality was found in systemic examination and blood tests. A biopsy specimen of pigmentation of her back showed there was increased pigmentation within the basal keratinocytes, with focal incontinentia pigmenti. Notable lymphangiectasis could also be seen in the mid part of dermis, which had never previously been described. The biopsy of scaling erythemas of her hand showed dominant hyperkeratosis with focal parakeratosis, acanthosis and papillomatous hyperplasia in the epidermis. The diagnosis of linear and whorled nevoid hypermelanosis (LWNH) complicated with inflammatory linear verrucous epidermal nevus and ichthyosis vulgaris was made in accordance with clinical and pathological manifestations. LWNH ought to be differentiated from incontinentia pigmenti and hypomelanosis of Ito. 相似文献
13.
14.
Yuksek J Sezer E Erbil AH Arca E Taştan HB Kurumlu Z Demiriz M 《Dermatology online journal》2007,13(3):23
Linear and whorled nevoid hypermelanosis (LWNH) is a rare skin condition characterized by swirls and whorls of hyperpigmented macules in a reticulate pattern along Blaschko's lines; approximately 40 cases have been reported in the English language literature. We report a case of LWNH occurring in a 20-year-old man with widespread involvement over the trunk, face, upper limbs, and genitalia in association with scoliosis. A small hyperpigmented area on the abdomen was treated with a medium-depth chemical peel regimen using 70 percent glycolic acid and 35 percent trichloroacetic acid with no benefit. This is the first report of LWNH treated with medium-depth chemical peel. 相似文献
15.
16.
Linear and whorled nevoid hypermelanosis 总被引:6,自引:0,他引:6
D C Kalter W A Griffiths D J Atherton 《Journal of the American Academy of Dermatology》1988,19(6):1037-1044
Two cases are presented of congenital linear and whorled hypermelanosis. Hyperpigmented macules in streaky configurations along Blaschko's lines appeared gradually after birth. Histologic examination revealed prominent epidermal melanocytes and irregular basal layer hyperpigmentation with normal melanosomes. This condition must be differentiated from incontinentia pigmenti, early systematized epidermal nevus, extensive hypomelanosis of Ito, and chimerism. Other similar case reports from the literature suggest that incidence is sporadic and may be associated with more serious congenital anomalies. The patterning is the inverse to that found in hypomelanosis of Ito. Developmental somatic mosaicism may be responsible for this patterned hypermelanosis. 相似文献
17.
Linear and whorled naevoid hypermelanosis: a case with systemic involvement and trisomy 18 mosaicism
Komine M Hino M Shiina M Kanazawa I Soma Y Tamaki K 《The British journal of dermatology》2002,146(3):500-502
We describe a 20-year-old woman with trisomy 18 mosaicism, who presented with skeletal anomalies, epilepsy, mental retardation, and linear and whorled naevoid hypermelanosis. 相似文献