美国药典（24版）：蛇根木（Rauwolfia Serpentina）

本品为夹竹桃科蛇根木 Rauwolfia serpentina(L.)Bentham ex Kurz 的干燥根,有时带有残存的根茎和地上茎基。所含利血平-利血胺(reserpine-rescinnamine)类生物碱以利血平计,不应低于0.15％。包装和贮存贮存于密封容器中,置于室温、干燥处,并防虫蛀(见一般注意事项中有关植物药和动物     

Synthesis,characterization, and anti-cancer activity of emodin-Mn（Ⅱ） metal complex

To synthesize and characterize a novel metal complex of Mn （Ⅱ） with emodin, and evaluate its anti-cancer activity. The elemental analyses, IR, UV-vis, atomic absorption spectroscopy, TG-DSC, ^1H NMR, and ^13C NMR data were used to characterize the structure of the complex. The cytotoxicity of the complex against the human cancer cell lines HepG2, HeLa, MCF-7, B16, and MDA-MB-231 was tested by the MTT assay and flow cytometry. Emodin was coordinated with Mn（Ⅱ） through the 9-C=O and 1-OH, and the general formula of the complex was Mn（Ⅱ） （emodin）2.2H/O. In studies of the cytotoxicity, the complex exhibited significant activity, and the IC50 values of the complex against five cancer cell lines improved approximately three-fold compared with those of emodin. The complex could induce cell morphological changes, decrease the percentage of viability, and induce G0/G1 phase arrest and apoptosis in cancer cells. The coordination of emodin with Mn（Ⅱ） can improve its anticancer activity, and the complex Mn（Ⅱ） （emodin）2.2H2O could be studied further as a promising anticancer drug.     

Parsley： a review of ethnopharmacology,phytochemistry and bio- logical activities

OBJECTIVE： To summarize comprehensive informa- tion concerning ethnomedicinal uses, phytochem- istry, and pharmacological activities of parsley. METHODS： Databases including PubMed, Scopus, Google Scholar, and Web of Science were searched for studies focusing on the ethnomedicinal use, phytochemical compounds and biological and pharmacological activities of parsley. Data were col- lected from 1966 to 2013. The search terms were： ＂Parsley＂ or ＂Petroselinum crispum＂ or ＂Petroseli-num hortence＂. RESULTS： Parsley has been used as carminative, gastro tonic, diuretic, antiseptic of urinary tract, an- ti-urolithiasis, anti-dote and anti-inflammatory and for the treatment of amenorrhea, dysmenorrhea, gastrointestinal disorder, hypertension, cardiac dis- ease, urinary disease, otitis, sniffle, diabetes and al- so various dermal disease in traditional and folklore medicines. Phenolic compounds and flavonoids particularly apigenin, apiin and 6-Acetylapiin, es- sential oil mainly myristicin and apiol, and also cou- marins are the active compounds identified in Petroselinum crispum. Wide range of pharmacolog- ical activity including antioxidant, hepatoprotec- tive, brain protective, anti-diabetic, analgesic, spas- molytic, immunosuppressant, anti-platelet, gastro- protective, cytoprotective, laxative, estrogenic, di- uretic, hypotensive, antibacterial and antifungal ac- tivities have been exhibited for this plant in mod- ern medicine. CONCLUSION： It is expectant that this study result- ed in improvement the tendencies toward Petrose- linum crispum as a useful and important medicinal plant with wide range of proven medicinal activity.     

Ethnopharmacology,phytochemistry and pharmacology of Tephrosia purpurea简

Tephrosiapurpurea （L.） Pers. is popularly known as ＇Sarapunkha＂ in classical Ayurvedic texts. It is a perennial plant belonging to the family Fabaceae, and occurs throughout the Indian subcontinent. T. purpurea is traditionally used to treat spleenomegaly, cirrhosis, cough and cold, abdominal swelling and as an antidote in the Ayurvedic system of medicine. Phytochemical investigations indicate the presence of semiglabrin, pongamole, lanceolatins A and B, rutin, lupeol, and β-sitosterol. Flavonoids including （＋）-tephrorin A and B, （＋）-tephrosone, an isoflavone, 7, 4＇-dihydroxy-3＇, 5＇-dimethoxyisoflavone and a chalcone, （＋）-tephropurpurin were isolated from the whole plant. Pharmacological activities of different parts of the plant reported include anti-inflammatory, antiulcer, antimicrobial, antioxidant, antiallergic, antidiabetic, hepatoprotective, antitumor and insect repellent activity. In the present review, the literature on the phytochemical and pharmacological investigations of Tephrosia purpurea （L.） Pers. are summarized to August, 2012.     

图说中医（一四○）：中医诊法（八十九）——脏腑辨证（7）

1．脾胃为仓廪之官．主纳饮食。化水谷．司中气。气虚表现为倦怠无力、行动气短、懒言、嗜卧。气滞则表现为脘腹胀满。     

温病专题讲座：第五讲风温（春温,冬温）

(从本讲开始,将温病之辨证论治,分为四讲)冬春两季感受风温邪气的外感发热病,名为风温。发于冬天的名冬温,发于春令初起即见气分证或营分证的名春温,辨证论治均可参考。流行性脑脊髓膜炎,冬春季的感冒及流行性感冒等病,可参考本讲的论述进行辨证论治。病因病理风温邪气为本病的致病原因。春季温暖多风或冬     

Post-marketing safety monitoring of Shenqifuzheng injection： a solution made of Dangshen（Radix Codonopsis）and Huangqi（Radix Astragali Mongolici）

OBJECTIVE：Toidentify the potential risk factors associated with Shenqifuzheng injection（SFI）, a solution made of Dangshen（Radix Codonopsis） and Huangqi（Radix Astragali Mongolici）, for the timely provision of information to regulatory authorities.METHODS： A comprehensive analysis of the production process, quality standards, pharmacology,post-marketing clinical studies, and safety evaluation using the primary literature of adverse reactions（ADR）, case analyses, and systematic reviews,intensive hospital safety monitoring of post-marketing drugs, and data provided by the hospital in-formationsystem（HIS）.RESULTS： Sub-acute toxicity tests suggesting that a dose of 15 mL/kg（concentrated solution） had specific biological effects, whereas a smaller dose engendered no observable effects. Long-term toxicity testing in domestic rabbits showed that after SFI was administered for 90 days, the animals in each dosing group showed no chronic toxic reactions. Among 20 100 cases observed, the incidence of an ADR was 1.85‰. From March to November 2013,of the leading institutions and 22 sub-centers involved in the post-marketing clinical safety intensive hospital monitoring, 21 units completed 8484 cases of monitoring, and reported 23 cases of adverse reactions. No damage to renal function was found using SFI ata dosageanda treatment course larger and longer than that recommended for the adjuvant treatment of tumors. This could reduce the mortality rate of admitted patients based on the analysis of the data provided by the HIS. A total of 16 clinical case reports of adverse reactions related to SFI in 1999-2012 were obtained through literature retrieval. These reports contained information concerning 17 cases, with adverse reaction symptoms including thrombocytopenia, rash,chills,feeling cold,palpitation,dyspnea,edemaofa lower extremity, palpebral edema, and superficial vein in flammation,among others.CONCLUSION： This study introduces ＂get full access＂ to the flow of information on medicines reg     

我国桑属（Morus L．）药用植物资源化学研究进展

我国已有5000年栽桑养蚕的文明史,是世界桑资源分布中心。目前的桑园面积达800万hm^2,2000万户农民从事栽桑养蚕,有利地促进了我国蚕丝产量占有国际70％-80％的份额。随着桑蚕产业的大力发展,近年来国内外科研工作者对桑资源研究取得了长足进展。基于中药资源化学研究思路与方法对桑资源性成分研究、动态评价以及桑资源的多途径、多层次开发利用研究等方面进行了较为系统归纳和总结,以期为桑资源产业链的发展提供依据与参考。     

太极拳：中华民族的瑰宝（二）

哲理丰富的科学运动 太极拳又被称为“哲拳”。是荟萃了诸多学科和民族文化的精华而逐渐发展、完善起来的优秀运动项目。     

Comparative Study on the Effect of Baihui （GV 20）, Shuigou （GV 26） and Shenmen （HT 7） on Cognition of Patients with Vascular Dementia

目的:探讨百会、水沟、神门改善血管性痴呆(VD)患者认知功能的相对特异性.方法:50例血管性痴呆患者,随机分为5组,分别治以常规穴位针刺,常规穴位加用百会穴,加用水沟穴,加用神门穴,加用百会、水沟和神门3穴.治疗前后运用老年认知功能量表(SECF)进行测评.结果:常规穴位加用百会、水沟、神门等穴位治疗后,SECF总分有显著提高;加用百会穴治疗后,VD患者的定向、瞬间记忆、长回忆、动物名、划销和计算、分类与类同等方面评分有明显提高;加用水沟穴治疗后,VD患者的定向、划销和计算、分类与类同等方面评分有明显提高;加用神门穴治疗后,VD患者的数字广度、动物名、分类与类同等方面评分有明显提高.结论:百会、水沟、神门能够改善VD患者认知功能,三穴虽然分别有各自的相对特异性,但联合运用效果最佳.     

Effects of Hegu （LI 4） and Taichong （LR 3） on Vascular Dilation and Constriction in Migraine Patients

Hegu （LI 4） and Taichong （LR 3） are the Yuan- Primary acupoints of the Large Intestine and Liver Meridian, and are collectively named as Si Guan （four gates） point. Combined use of these two acupoints can harmonize yin and yang, regulate qi and blood, and balance ascending or descending. This paper attempts to study the effects of Si Guan point on the vascular dilation and constriction in migraine patients from the perspective of its feature.     

食姜美味（四）：凤凰姜糖

如果你前去湖南西部的旅游胜地凤凰古镇,有一样土特产可千万别忘记购买,那就是著名的＂凤凰姜糖＂。     

The 20^th Anniversary of World Federation of Acupuncture-Moxibustion Societies （WFAS） and International Acupuncture Congress （First Announcement） Beijing, China

With the advent of another fruitful and golden autumn, we joyfully greet the 20^th Anniversary of World Federation of Acupuncture-Moxibustion （WFAS）. It has been growing day by day and been regarded as an important academic power in traditional medicine arena around the globe over the past twenty years under the care, cherish and support of acupuncture organizations and colleagues all over the world.     

Effects of Applying Acupuncture Therapy at Baihui （GV 20） and Zusanli （ST 36） on the Behave of Mice and Rats in the Depression Model （Abstract）

Objective: To study the effects of acupuncture therapy on the behave of depression model.     

Influence of Electroacupuncture at Taichong （LR 3） and Ququan （LR 8） on Hepatic Hemodynamics

Objective： To observe the influence Taichong （LR 3） and Ququan （LR 8） on patients with chronic hepatic diseases. of electroacupuncture hepatic hemodynamics （EA） at in the Methods： Sixty cases with chronic hepatic diseases were randomly divided into a Taichong （LR 3） group and a Ququan （LR 8） group, 30 cases in each group, and were respectively treated with electroacupuncture at Taichong （LR 3） and Ququan （LR 8）. The blood flow results of the hepatic artery and portal vein by color ultrasonic test were used as the objective indexes, to compare and observe the hemodynamics changes of the hepatic artery and portal vein in the patients before and after EA. Results： After EA, in Taichong （LR 3） group, the average velocity, the lowest velocity, resistance indexes and the highest velocity of blood flow of the hepatic artery, and the highest velocity, average velocity of blood flow of the portal vein, blood flow volume of the portal vein （PVBF）, total blood flow volume of the liver （TLBF）, and Doppler blood perfusion indexes of the hepatic artery （DPI） were all statistically different from those before intervention （all P~O,O5）, In Ququan （LR 81 group, the highest velocity, average velocity, lowest velocity and resistance indexes of blood flow of the hepatic artery, and the highest velocity and average velocity of blood flow of the portal vein, and PVBF were significantly different from those before intervention （P〈0.05）. The TLBF and DPI were significantly different from those before intervention （P〈0.01）. All various indexes were not statistically different between the two groups. Conclusion： EA at Taichong （LR 3） and Ququan （LR 8） can speed up blood flow velocity of the portal vein, increase PVBF, increase the TLBF, increase the resistance indexes of the hepatic artery, decrease the blood flow velocity of the hepatic artery, and decrease DPI in the liver.     

The 20^th Anniversary of the World Federation of Acupuncture-Moxibustion Societies （WFAS） and International Acupuncture Congress （First Announcement） Beijing, China

Withthe advent of another fruitful and golden autumn, we joyfully greet the twentieth anniversary of WorldFederation of Acupuncture-Moxibustion Societies .It has been growing day by day and been counted as an i m-portant academic powerintraditional medici…     

Effect of Puncturing Neiguan （PC 6） and Zusanli （ST 36） on Chemotherapy-related Vomiting from Platinum-involved Therapeutic Project： A Report of 26 Cases

目的：观察针刺内关、足三里穴对化疗所致恶心、呕吐的疗效。方法：26例行含铂类化疗方案的恶性肿瘤患者．在常规治疗呕吐的基础上，于化疗前、后针刺双足三里、内关穴，日2次，每次30min。直至化疗结束后3d。所有患者均采用自身前后对照的方法，即第一疗程用针刺，第二疗程则不用，反之第一疗程不用针刺。第二疗程则用。结果：针刺治疗组出现恶心、呕吐者15例，其中Ⅰ°6例，Ⅱ°5例，Ⅲ°2例，无Ⅳ度反应。急性呕吐11例，延迟呕吐4例，先期呕吐0例；对照组出现恶心、呕吐者19例，其中Ⅰ°5例．Ⅱ°9例，Ⅲ°4例，Ⅳ°1例；急性呕吐13例，延迟呕吐6例，先期呕吐0例；针刺治疗组的恶心呕吐发生率及呕吐程度均低于对照组（57．7％VS 73．1％，P〈0．01），且生活质量提高。结论：针刺双足三里、内关穴，可减轻含铂类化疗方案患者的胃肠道反应，提高患者生活的质量。