Nasopharyngeal Foreign Body in an Young Child

A number of articles on foreign body (FB) ingestion and inhalation have been reported in the literature. Of these, reports of foreign bodies lodging in nasopharynx after inhalation/ingestion are rare. A case of FB inhalation/ingestion presented with history of respiratory distress was admitted for suspected FB bronchus and kept for observation. On examination the child was not distressed and chest examination and X-ray were normal. After 2 days, however, X-ray nasopharynx was taken for rhinorrhoea, nose block and snoring since admission. A large metal nut was found in the roof of the nasopharynx. This case is reported for its rarity, unusual presentation and misleading history.     

A metallic nut in the cheek

A case of a metallic nut lodged in the cheek for two months is described.     

Adenoid cystic carcinoma of the nasopharynx: a case report]

Nasopharyngeal adenoid cystic carcinoma is a rare tumor, few cases have been reported in the literature. The aim of this report is to present a new case of an adenoid cystic carcinoma of the nasopharynx. We report the case of a 50 years-old woman presenting with an adenoid cystic carcinoma of the nasopharynx with diffuse pulmonary metastasis. The treatment combined chemotherapy, based on cisplatin and adriamycin drugs, and palliative radiation therapy at the dose of 30 Gy. The patient died 6 months after diagnosis establishment. The best treatment of adenoid cystic carcinoma is complete surgical resection but extended resection can be difficult in some locations as nasopharynx. The adjuvant radiation therapy seems to improve local control.     

Haemangiopericytoma of nasopharynx

A case of Haemangiopericytoma in the nasopharynx with lymph node metastasis is presented along with the review of literature.     

Tuberculosis associated with malignancy of the nasopharynx

A case of malignancy and tuberculosis occurring together in the nasopharynx is reported. The relevant literature on the association of these two diseases is reviewed.     

Muco-Epidermoid carcinoma of the nasopharynx

A rare case of mucoepidermoid carcinoma of the nasopharynx is reported. The salient features of the disease are discussed in the light of available literature.     

Chondrosarcoma of the nasopharynx

Chondrosarcoma of the nasopharynx is a rare entity, only four cases having been reported in the world literature to date one each by Wirth and Shimkin (1943), Timmis (1959) and Serba (1966) and Singh and Seth (1972). This paper adds a fifth case to the literature.     

Angiofibroma arising from nasal septum in adult male—A rare occurence

Angiofibroma is an unique problem faced by the otolaryngologist, due to its recurrence, occurence in a rather inaccessible area and troublesome bleeding during excision. It’s commonly known to arise from nasopharynx in adolescent males but extra nasopharyngeal extensions are not uncommon. Herewith we are presnting an extremely rare case of angiofibroma arising from the nasal septum in an adult male. To the best of our knowledge septal angiofibroma has not been reported in the relevant literature yet. The clinical features and management of this case are discussed in this paper.     

Extranodal manifestation of Rosai Dorfman Disease of the nasopharynx

The aim of presenting this case is to highlight the fact that extranodal manifestation of Rosai Dorfman Disease (RDD) without lymphadenopathy was seen in a teenaged girl with recurrent episodes of epistaxis, due to a lobulated mass in the nasopharynx, which mimicked malignancy. This case is a rare presentation because the extranodal manifestation of RDD in multisystem organs are reported in literature, but the nasopharyngeal manifestation without lymphadenopathy is unique. The clinical presentation and surgical management of the case by endoscopic sinus surgery, the aetiopathology, differential diagnosis and review of literature are described here.     

Primary lymphoepithelioma-like carcinoma of the lung

Lymphoepithelioma is an undifferentiated carcinoma with prominent lymphoid stroma in the nasopharynx. Tumors with similar histology have been reported with other localizations, including the lungs, and are designated as lymphoepithelioma-like carcinomas (LELC). Primary LELC of the lung is very rare, and scant information is available in the scientific literature. This paper details the case of a 25-year-old Caucasian male patient with the diagnosis (determined by thoracotomy) of primary LELC of the lung. Immunohistochemical analysis was negative for Epstein-Barr virus, as was the in situ hybridization of the tumor cells. Observation of the nasopharynx and a magnetic resonance image of the cavum were normal. Because the tumor (T4N2M0) could not be resected, the patient was treated with chemotherapy, carboplatin/5-fluorouracil, completing two cycles. The patient's condition worsened when he developed contralateral pneumonia, which was then followed by pericardial effusion. The patient died 36 h later from cardiac tamponade. Presented here is a revision of this rare pathology, not often reported in the literature.     

Foreign body in the nasopharynx of a child

Introduction of foreign body into the nasal cavity of the children by themselves is very common, but lodgment of foreign body in the nasopharyux following introduction through mouth is unusual. Here a case is presented from the Otorhinolaryngology department of S.S.K.M. Hospital, Kolkata, where a child was brought by their parents with history of introduction of a metallic foreign body in the mouth of the child by himself and this foreign body was found to be lodged in the nasopharynx of the child. The foreign body was removed orally in the out patient department. The patient returned home without any complication.     

Nasopharyngeal presentation of renal cell carcinoma

In this case report, we present a 50-year- old woman, who presented with severe headache as her only presenting clinical symptom due to nasopharyngeal mass. Histo-pathological evaluation of the biopsy from nasopharyngeal mass revealed clear cell carcinoma. On further evaluation, an asymptomatic mass was detected in the left kidney. The metastatic lesion was treated with palliative radiotherapy. A search of the literature revealed no reports of such unusual metastasis in the nasopharynx from a primary carcinoma of the renal origin.     

An Atypical Rare Case of Extracranial Craniopharyngioma

We present a case of a purely extracranial, infrasellar craniopharyngioma that initially presented as a mass in nose and nasopharynx. Craniopharyngiomas are usually located within the sella. Purely infrasellar craniopharyngiomas have only rarely been reported in the literature. A 55-year-old man presented with 8-month history of progressive headache and epistaxis. Rhinoscopy revealed polypoidal mass in both the nasal cavities and nasopharynx. Pre-operative biopsy suggested Craniopharyngioma. A battery of tests necessary for the diagnosis of Craniopharyngioma was done which excluded other possibilities. Surgical resection was done and histopathology thereafter was confirmatory of Craniopharyngioma. Adjuvant radiotherapy was given to the patient. The patient is doing well. The Rathke’s pouch arises from the roof of the primitive mouth and grows toward the brain at the fourth week of gestation. Normally, it loses its attachment with the stomadeum completely by the eighth week of gestation. The craniopharyngeal canal (CPC) extends from the floor of the sella to the vomer and may rarely give rise to ectopic craniopharyngiomas. This case shows that such ectopic tumors may arise anywhere along the CPC. We are documenting this case as an atypical rare case of craniopharyngioma probably originating from tooth primordia.     

Nasopharyngeal rhabdomyosarcoma

Nasopharyngeal Rhabdomyosarcama, a common soft tissue sarcoma in children, is a rare identity, only four cases so far have been reported as per the review of literature. Ours is the fifth case presented exclusively in the nasopharynx, which is reported, hereby. The prognosis of this clinical entity is always gloomy and the modality of thr treatment is always surgery, chemotherapy and radiotherapy.     

Clival chordomas

Three cases of clival chordomas are reviewed and the findings are compared to those in the recent literature. In the first case the tumour arose from the basion, spreading downwards to invade the upper cervical canal and the paravertebral fascial planes. The second case is a rare case since it affects a 12 year old pre-adolescent boy. The third case showed the characteristic features of petro-clival erosion and a large extracranial component in the nasopharynx. In all three cases, computed tomography was an excellent modality for demonstrating bone destruction, sequestra and calcification but inferior to magnetic resonance imaging (MRI) in demonstrating the soft tissue extent of the tumour. The multiplanar capability of MRI was found to be particularly useful for planning treatment. Vertebral angiography can demonstrate the tumours by vessel displacement, encasement and vascular staining. Two cases had angiography and demonstrated tumour blush. Pre-operative embolization was helpful in one case.     

Neglected iron nail in the larynx

Various foreign bodies in children have been reported in the literature, but a metallic foreign body neglected for about three weeks in the laynx of a child is quite unusual. An interesting case report of a curved metallic Iron nail as a neglected foreign body in the laynx which was found lying anteriposteriorly between the vocal cords is presented.     

Isolated Lymphangiomatous Polyp Nasopharynx in an Adult First Case Report in English Literature

Lymphangiomas are rare benign, hamartomatous, congenital malformations of the lymphatic system involving the skin and subcutaneous tissues of head, neck and oral cavity. Occasional adult onset cases occur, this condition is thought to be a developmental malformation of lymph vessels which have poor communication with normal lymph system. Most of these malformations are present at birth or appear within two years of life. 75 % of cases occur in head and neck area, submandibular and parotid being the most affected parts. Lymphangioma arising in nasopharynx and in an adult has not been reported in english literature. This prompted us to report the very first case of Lymphangioma Nasopharynx.     

Extranasopharyngeal angiofibroma arising from the infratemporal region

Angiofibroma is a histologically benign but locally invasive tumour of the blood vessels characterized by architecturally irregular vessels set in a fibrous stroma. The commonest site for occurrence of these tumours in the body is the nasopharynx. It is rare to find extranasopharyngeal origin of angiofibromas. The infratemporal fossa is a very rare site of extra nasopharyngeal angiofibroma with only 4 cases reported in the literature. We report here a case of a vascular mass arising from the infratemporal fossa of a 13-year-old boy that was confirmed to be a case of angiofibroma histopathologically. A review is also made of the other reported cases of angiofibroma arising from the infratemporal fossa. The likely theory of origin of the tumour and its management is also discussed.     

Primary clear cell carcinoma of the nasopharynx： a case report

Primary dear cell carcinoma of the nasopharynx is a rare and locally invasive minor salivary gland neoplasm, only two cases have been reported yet in the literature. Now a 57-year man, with primary nasopharyngeal clear carcinoma,received radiotherapy and chemotherapy. After treatment, the mass of nasopharynx visibly reduced. Follow-up two months and repeated MRI, CT, abdominal B-ultrasonograpy, electronic nasopharyngoscopy, no tumor recurrence or metastasis.     

鼻咽部神经内分泌癌的病理特征和临床分析

目的 探讨鼻咽部神经内分泌癌（neuroendocrine carcinoma，NEC）的临床病理特征、免疫组化特点、治疗方法及预后。方法 回顾性分析12例NEC患者的临床和病理资料，并复习相关文献。 结果 12例患者中，男性10例，女性2例，平均年龄49.4岁，病理类型均为小细胞型NEC。光镜下可见较小瘤细胞，呈圆形、卵圆形和梭形，核深染，胞浆少，核浆比例高，伴有较明显的病理性核分裂象，染色质细腻。免疫表型：CgA、Syn、CD56和EBERs阳性或部分阳性者分别有6例、10例、9例和3例。临床分期Ⅰ期1例，Ⅱ期1例，Ⅲ期4例，Ⅳ期5例，分期不详1例。所有患者均接受放疗和（或）化疗，至随访结束存活者9例，死亡3例。结论 鼻咽部神经内分泌癌临床上较少见，好发于中老年男性，病理类型以小细胞型为主，易出现颈部淋巴转移，就诊时大部分已处中晚期，治疗以放化疗为主。