口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

口腔念珠菌病患者唾液硝酸根分泌能力升高

Objective To observe the alterations of saliva nitrate and nitrite level in patients with oral candidiasis. Methods Parotid saliva and whole saliva were collected from 33 patients and 34 healthy volunteers. Concentrations of nitrate and nitrite in saliva were determined by high-performance liquid chromatography. Follow-up observation was performed on 10 patients after treatment. The data were statistically analyzed with independent-samples t test or paired-samples t test at α=0. 05. Results There was significant increase of the concentrations and secretion rate of parotid saliva nitrate in patient group as compared with controls: (49. 70±0. 50) vs (21.51±0. 60) mg/L (t=2. 692,P=0. 009) and (27.71±0. 50) vs (12. 55±0. 60)μg/min (t=2. 554, P=0. 013), respectively. Significantly increased concentrations and secretion rate of nitrate and nitrite [nitrate: (6. 46±0. 94) vs (1.11±0. 70) mg/L (t=3.792,P=0.000); nitrite: (8.48±0.58) vs (3.39±0.53) mg/L (t=2.888,P=0.005); nitrate secretion rate: (10. 57±0. 91) vs (2. 10±0. 74)μg/min (t=3.464, P=0. 001) ; nitrite secretion rate:(13.91±0.55) vs (6.42±0.58)μg,/min (t=2.397,P=0.020)]were revealed in whole saliva of patients group. Significantly decreased nitrate and nitrite levels were also observed in patients after treatment, especially the changes of parotid saliva nitrate secretion rate [(37. 50±0. 50) vs (14. 34±0. 64)μg/min (t=3. 142, P=0. 012)], whole saliva nitrate [(14.29±1.01) vs (2. 59±1.03) mg/L (t=3.475, P=0. 007)]and whole saliva nitrate secretion rate [(25.97±0. 93) vs (4. 12±1.00)μg/min (t=3. 922,P=0. 003)]. Conclusion The present study revealed the significant increase of salivary nitrate and nitrite level in patients with oral candidiasis is considered to be associated with the host defense reaction.     

含橄榄油脂肪乳剂在肝叶切除患者术后肠外营养中的应用

Objective To assess the safety and efficacy of an olive oil-based lipid emulsion for parenteral nutrition in patients after hepatectomy.Methods Thirty-one postoperative patients with elective hepateetomy were randomized to receive isonitrogenous,isocalorie parenteral nutrition over 6 days after liver lobectomy(48-72hours)with either olive oil-based lipid emulsion(study group,n=15)or standard soybean oil emulsion(control group,n=16).The liver function and plasma protoins were assessed using peripheral venous blood collected before surgery,one day after surgery,and 7 days after surgery.The safety profiles of emulsion supports and postoperative rehabilitation were also assessed.Results The preoperative serum levels of total bilirubin,direct bilirubin,alanine amiotransferase,aspartate aminotransferase,alkaline phosphatase,total protein,albumin,and prealbumin were comparable between the two groups(all P>0.05).Although the Postoperative safety profile and liver function were not significantly different between two groups(all P>0.05),plasma total proteins,albumin,and prealbumin returned to the normal levels significantly faster in the study group than in control group[(57.57±9.84)g/L vs.(47.76±6.53)g/L,P=0.000;(31.29±3.11)g/L vs.(26.34±4.87)g/L,P=0.000;(0.188±0.059)g/L vs.(0.103±0.037)g/L,P=0.000]on the 7th Postoperative day,and the Postoperative hospital stay was also significantly shorter in the study group[(13.1±1.2)d vs.(15.2±1.1)d,P=0.041].The incidence of postoperative complications in study group and control group was 26.7%and 31.3%.respectively.Conclusions Treatment with the new olive oil-based lipid emulsion is weU tolerated in hepatectomy patients.It can speed up plasma proteins recovery and may shorten postoperative hospital stay,although it does not remarkably decrease the incidence of postoperative complications.