Rotational position of toric soft contact lenses on the eye—Clinical judgments

This study investigated the accuracy and reliability of experienced contact lens practitioners in estimating the rotational position of a toric soft contact lens on the eye. The study also evaluated whether some markings of selected round toric soft lenses are superior to others in assisting clinicians who are making lens rotational position judgments.Estimates of on-the-eye landmark position of toric soft contact lenses were found to be within 1 to 12 degrees of true position. The subject, rather than the type of lens marking, accounted for most of the error in lens rotation judgment.     

The effects of β-adrenergic agonists on cone systems in the cat eye

The effects of the -adrenergic agonist nylidrin and the ₂-adrenergic agonist clenbuterol on electroretinogram and optic nerve response were studied in the isolated and arterially perfused, light-adapted cat eye. Two cone mechanisms, short wavelength-sensitive and long wavelength-sensitive, were functionally separated by means of intense yellow adaptation. A reversible increase in b-wave amplitude in response to nylidrin or clenbuterol was observed for the cone systems. Both drugs also caused a reversible alteration in configuration of the optic nerve response, mainly a depression of the late components related in time to the changes in the electroretinogram. These observations suggest that -adrenergic mechanisms are involved in cone systems. The greater increase in b-wave amplitude on 558-nm stimulation and preliminary evidence for greater increase in sensitivity observed in the V-log I function compared with 439 nm further suggest that the short and long wavelength cone systems are affected differently by -adrenergic agonists.     

Does the noise matter? Effects of different kinematogram types on smooth pursuit eye movements and perception

We investigated how the human visual system and the pursuit system react to visual motion noise. We presented three different types of random-dot kinematograms at five different coherence levels. For transparent motion, the signal and noise labels on each dot were preserved throughout each trial, and noise dots moved with the same speed as the signal dots but in fixed random directions. For white noise motion, every 20 ms the signal and noise labels were randomly assigned to each dot and noise dots appeared at random positions. For Brownian motion, signal and noise labels were also randomly assigned, but the noise dots moved at the signal speed in a direction that varied randomly from moment to moment. Neither pursuit latency nor early eye acceleration differed among the different types of kinematograms. Late acceleration, pursuit gain, and perceived speed all depended on kinematogram type, with good agreement between pursuit gain and perceived speed. For transparent motion, pursuit gain and perceived speed were independent of coherence level. For white and Brownian motions, pursuit gain and perceived speed increased with coherence but were higher for white than for Brownian motion. This suggests that under our conditions, the pursuit system integrates across all directions of motion but not across all speeds.