Dépister la dénutrition de l’enfant

Protein energy malnutrition (PEM) occurs when energy and protein intake do not meet requirements. PEM increases both morbidity and mortality of a given disease. The Nutrition Committee of the French Paediatric Society recommends weighing and measuring any child when hospitalized or seen as outpatients. Body mass index (BMI) must be calculated and analyzed according to references anytime growth kinetics cannot be analyzed. Any child with a BMI below the third centile or –2 standard deviations for age and sex needs to be examined looking for clinical signs of malnutrition and signs orienting toward an aetiology, and requires having his BMI and height dynamics plotted on a chart. PEM warrants drawing a nutritional strategy along with the global care plan. A target weight needs to be determined as well as the quantitative, qualitative and modality of nutritional care. This plan must be evaluated afterwards in order to adapt nutritional therapy.     

Un parcours de soins spécifique pour la dénutrition

Malnutrition has been considered as a hospital illness for nearly forty years. Despite this fact, we know this malnutrition finds its roots earlier within the community. Therefore, considering the evolutionary history of this pathology even an early hospital screening proves to be overdue. Nutritional condition often deteriorates during hospitalization and, with most favorable treatment conditions, increasingly short lengths of stay rarely allow for a complete correction. Coordination with home care network becomes essential to maintain nutritional treatment that was initiated in hospital. Since 2012, French health authorities proposes different care pathways involving patients as well as doctors, paramedical and medico-social practitioners in malnutrition prevention, early detection and home medical care. It is now essential to consider that malnutrition, like any chronic disease, asks for a specific care pathway, whatever the age of the patient.     

Recherche de paramètres structuraux influencant l'activité anthelminthique d'urées dérivées de thiadiazoles

Thiadiazole derivatives were synthesized and their anthelmintic activities were tested against a nematode: Syphacia obvelata and a cestode: Hymenolepis nana. The effect of electronic parameters and lipophilicity on activity was determined by means of a multivariate analysis method: the principal components analysis.