分析慢性咽喉炎应用蓝芩口服液治疗的临床效果

目的 :分析慢性咽喉炎应用蓝芩口服液治疗的临床效果.方法 :选取2016年1月到2016年11月于本院接受治疗的94例慢性咽喉炎患者,按照数字随机划分法分为参照组与试验组(n=47).为两组患者实施常规治疗,试验组在此基础上服用蓝芩口服液,对比两组患者的症状缓解时间以及临床治疗总有效率.结果 :试验组患者咽部疼痛充血、咽部粘膜干燥、咽部干痒等症状缓解时间均优于参照组患者,差异比较具有统计学意义(P<0.05);参照组患者临床治疗总有效率为87.23%,明确低于试验组患者总有效率97.87%,数据对比具有统计学意义(P<0.05).结论 :常规治疗基础上联合应用蓝芩口服液,能够提升慢性咽喉炎患者的临床总有效率,快速缓解患者的各项临床症状,药物应用价值较高.     

蓝芩口服液联合持续气道无创正压通气法治疗以慢性咽喉炎为主诉的OSA患者临床效果分析

目的观察蓝芩口服液联合持续气道正压通气(CPAP)治疗以慢性咽喉炎为主诉的阻塞性睡眠呼吸暂停(OSA)患者的效果。方法将我院62例以慢性咽喉炎为主诉的OSA患者随机分为观察组与对照组各31例。对照组行CPAP治疗,观察组进行蓝芩口服液联合CPAP治疗。比较两组慢性咽喉炎症状、患者治疗的依从性和呼吸暂停低通气指数(AHI)、咽部症状视觉模拟评分(VAS)和STOP-Bang量表(SBQ)评分情况、血清干扰素-(IFN-)、白介素-4(IL-4)的水平。结果治疗后,观察组患者咽部黏膜干燥、咽部异物感、咽部干痒、咽部疼痛出血缓解时间短于对照组(P0.05);观察组患者用机时间、每周使用频率噶高于对照组(P0.05);两组患者AHI、VAS、SBQ均下降,观察组AHI、VAS、SBQ均低于对照组(P0.05);两组患者IFN-水平下降,IL-4水平增高;观察组IFN-水平低于对照组,IL-4水平高于对照组(P0.05)。结论对于以慢性咽喉炎为主诉的OSA患者,蓝芩口服液联合CPAP治疗后咽部症状缓解明显,患者治疗依从性好,值得临床一线推广。     

应用蓝芩口服液治疗慢性咽炎的疗效观察

目的：探讨分析应用蓝芩口服液治疗慢性咽炎的临床疗效。方法：选取2012年6月～2013年6月间我院收治的慢性咽炎患者78例作为研究对象,采用随机数字表法将其分为对照组（39例）和研究组（39例）,应用利咽解毒冲剂为对照组患者进行治疗,应用蓝岑口服液为研究组患者进行治疗,观察对比两组患者的临床疗效,并将对比的结果及两组患者的临床资料进行回顾性的分析。结果：研究组患者治疗的总有效率为92.31%,对照组患者治疗的总有效率为74.36%,研究组患者的临床疗效明显优于对照组患者,差异显著(P＜0.05）,具有统计学意义。经过一段时间的治疗,研究组患者咽部疼痛的改善时间为（3.25±1.29）d,咽部异物感的改善时间为（3.19±1.14）d,咳嗽痰稠的改善时间为（4.34±1.12）d;对照组患者咽部疼痛的改善时间为（5.57±1.02）d,咽部异物感的改善时间为（4.79±1.28）d,咳嗽痰稠的改善时间为（6.29±1.96）d。研究组患者各种临床症状的改善时间明显短于对照组患者,差异显著(P＜0.05）,具有统计学意义。结论：应用蓝芩口服液治疗慢性咽炎的临床疗效显著,值得在临床上推广应用。     

竹沥胶囊治疗急性咽喉炎40例的临床观察

目的:观察竹沥胶囊治疗急性咽喉炎的临床疗效及不良反应。方法:将符合急性咽喉炎诊断标准的80例患者按照就诊次序随机分为竹沥胶囊组和鲜竹沥口服液组,每组40例。两组分别在常规治疗基础上加服竹沥胶囊(0.1mg/次,tid)和鲜竹沥口服液(30ml/次,tid),每日密切观察患者体温、咽痛、咽部红肿以及咳嗽、咯痰等临床症状变化。结果:两组患者服用药物后体温均下降,其中竹沥胶囊组患者治疗后体温下降更为明显,治疗前后比较具有统计学差异(P=0.011),且与对照组比较也具有统计学差异(P=0.023)。竹沥胶囊组患者服用后咽痛、咳嗽、咯痰等症状明显改善,改善时间较鲜竹沥口服液组缩短1天,两组比较差异具有统计学意义(P=0.0011,P=0.0085,P=0.010)。竹沥胶囊组咽痛,咽部红肿、咳嗽、咯痰等症状也明显改善,其总有效率为97.5%;鲜竹沥口服液组总有效率80.0%。两组比较差异具有统计学意义(χ2=6.13,P=0.013)。两组均未见明显的不良反应。结论:竹沥胶囊治疗急性咽喉炎在改善咽部症状方面优于鲜竹沥口服液。     

不同雾化吸入方法治疗慢性咽喉炎疗效比较

目的：观察两种雾化吸入方法治疗慢性咽喉炎的效果.方法：90例慢性咽喉患者分为两组,观察组应用氧气驱动雾化吸入器,对照组采用超声雾化器.结果：观察组症状改善时间（6.6±2.1d）短于对照组（1o.5±2.6d,P＜0.05）,治疗舒适度（3.94±0.89）高于对照组（2.13±1.25,P＜0.05）;观察组总有效率（95.56％）高于对照组（73.33％,P＜0.05）.结论：氧气驱动雾化吸入治疗慢性咽喉炎效果优于超声雾化吸入.     

胃食管返流性疾病致咽喉炎71例临床分析

目的:探讨胃食管返流性疾病致咽喉炎的诊疗及其发生的影响因素.方法:对疑似返流性咽喉炎患者71例随机分成两组,治疗组(n=43)应用抑酸药联合胃动力药物配合治疗咽喉炎药物治疗；对照组(n=28)单用治疗咽喉炎药物治疗,对两组咽部症状缓解及病变改善情况进行统计学比较.结果:返流性咽喉炎体征多样化；治疗组43例,治疗有效率88.4％,对照组28例,治疗有效率67.9％,两组疗效有统计学差异(P＜0.05).结论:喉咽返流是导致慢性咽炎难治的重要病因,使用抑酸药联合胃动力药物,同时加用治疗咽喉炎药物治疗,可明显改善返流性咽喉炎的症状和体征.     

蓝芩口服液联合利巴韦林治疗小儿手足口病的效果及安全性观察

目的:观察蓝芩口服液联合利巴韦林治疗小儿手足口病的效果及安全性。方法:选取134例手足口病患儿作为研究对象,按照随机数字表法将其分为对照组和观察组各67例。对照组给予利巴韦林治疗,观察组在对照组的基础上联合蓝芩口服液治疗。比较两组临床疗效、症状改善时间、住院时间、超敏C反应蛋白(hs-CRP)水平及用药安全性。结果:观察组的治疗有效率为91.04%(61/67),明显高于对照组的74.63%(50/67),差异有统计学意义(P<0.05);观察组症状改善时间及住院时间均明显短于对照组,差异有统计学意义(P<0.05);治疗后观察组hs-CRP水平明显低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:与单用利巴韦林相比,蓝芩口服液联合利巴韦林治疗手足口病的效果更显著,可有效改善患儿的临床症状,降低炎性因子水平,缩短患儿住院时间,且安全性好。     

炎琥宁联合蓝芩口服液治疗手足口病的临床观察和护理

目的 炎琥宁联合蓝芩口服液治疗手足口病的临床观察及护理.方法 选择我院2012年1月至2013年1月收治手足口病患儿中随机选择100例,随机分组为对照组和治疗组,各组50例,对照组采用炎琥宁常规治疗,治疗组在常规组基础上联合蓝芩口服液治疗,观察两组治疗效果.结果 治疗组显效率和有效率明显高于对照组,两组患者比较差异有统计学意义（P＜0.05）.结论 蓝芩口服液联合炎琥宁治疗小儿手足口病临床疗效明显优于单纯使用炎琥宁治疗,临床效果满意.     

40例手足口病患儿给予蓝芩口服液治疗的效果观察

目的：观察蓝芩口服液在手足口病患儿中治疗的效果,为临床后期的治疗提供参考。方法选取2013年1月～2014年2月期间门诊收入的80例手足口病患儿为研究对象,将其按照不同治疗方式分成观察组与对照组,每组各40例。两组均给予常规治疗,对照组患儿在常规基础上加双黄连口服液,观察组患儿在常规基础上加蓝芩口服液。观察经治疗后患儿的一般情况。结果经治疗后,观察组总有效率为97.5%,比对照组高出20.0%;观察组与对照组在临床总有效率、症状消失时间（退热时间、皮疹及疱疹消失时间）比较,具有显著统计学差异性（P＜0.05）。结论蓝芩口服液是治疗小儿手足口病的安全、有效药物。     

回生口服液联合化疗治疗中晚期消化道肿瘤患者的效果观察

目的 观察回生口服液联合化疗治疗中晚期消化道肿瘤的临床效果.方法 将73例中晚期消化道肿瘤患者随机分为对照组36例（单纯化疗）和治疗组37例（回生口服液联合化疗）,治疗2个周期,观察近期临床疗效、不良反应、生存质量情况.结果 对照组近期治疗总有效率为25.0％,治疗组为48.6％,两组总有效率比较,差异有统计学意义（P＜0.05）.治疗组与对照组相比较少出现Ⅲ、Ⅳ度不良反应,Ⅲ、Ⅳ度白细胞减少、血小板减少、贫血、恶心及呕吐两组相比,差异均有统计学意义（P＜0.05）,其余不良反应两组相比,差异均无统计学意义（P＞0.05）.对照组治疗后卡氏评分值有所下降,但治疗前后比较差异无统计学意义（P＞0.05）;治疗组治疗后卡氏评分值上升,治疗前后比较,差异有高度统计学意义（P＜0.01）,两组治疗后组间比较,差异有高度统计学意义（P＜0.01）.结论 回生口服液联合化疗治疗中晚期消化道肿瘤可以提高患者近期疗效,减少不良反应发生率,提高患者生活质量.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.