急性胰腺炎患者应用循证护理的效果探讨

目的探讨急性胰腺炎患者应用循证护理的效果。方法在2016年4月至2017年8月,选取本院急性胰腺炎患者82例,均分为对照组与观察组,对照组给予常规护理,观察组给予循证护理,观察患者体温恢复正常时间、腹痛消失时间、住院时间、生存质量及护理满意度。结果观察组患者体温恢复正常时间、腹痛消失时间、住院时间比对照组少,生存质量比对照组高,护理满意度比对照组高,P0.05。结论给予急性胰腺炎患者循证护理,能缓解患者临床症状,减少住院时间,促进身体恢复,提高生存质量,获得较好的护理满意度,值得借鉴。     

循证护理用于重症急性胰腺炎的效果观察

目的:观察循证护理用于重症急性胰腺炎的效果。方法:选择2015年2月—2018年1月我院收治的重症急性胰腺炎患者86例,随机将患者分为对照组和研究组各43例。对照组给予常规护理,研究组给予循证护理,比较两组护理效果、腹痛消失时间、体温恢复正常时间、住院时间、并发症及患者的满意度。结果:研究组护理总有效率高于对照组,腹痛消失时间、体温恢复正常时间、住院时间均明显短于对照组,并发症明显少于对照组,患者满意度高于对照组,差异均有统计学意义(P<0.05)。结论:循证护理用于重症急性胰腺炎可快速改善患者症状,减少并发症,促进患者康复,提高护理满意度,有助于减少医疗纠纷。     

急性坏死性胰腺炎的围术期护理干预效果观察

目的探讨急性坏死性胰腺炎的围术期护理干预效果。方法选取2013年6月至2015年6月我院所诊治的152例急性坏死性胰腺炎患者作为研究对象,并根据护理方法的不同将其分为传统组与循证组,传统组的患者应用常规护理方法进行护理,对比分析两组患者的临床护理效果。结果循证组患者的平均住院时间,并发症率以及临床症状改善情况与患者满意度均明显优于对照组(P0.05),存在统计学差异。结论对急性坏死性胰腺炎患者实施循证护理能够有效的改善患者临床症状,降低并发症的发生率,缩短治疗时间,能够有效减轻患者经济压力,改善患者生活质量,临床应用价值明显。     

循证护理在重症急性胰腺炎护理当中的应用效果及对护理质量的影响

目的 研究分析循证护理在重症急性胰腺炎护理当中的应用效果及对护理质量的影响.方法 回顾本院2014年3月～2016年5月期间重症急性胰腺炎患者128例资料并根据干预方式随机分组.常规组护理当中应用一般护理;循证组护理当中应用循证护理.比较两组患者对本次护理服务的满意度;腹痛消失时间、发热持续时间、平均住院时间、血淀粉酶、尿淀粉酶水平;死亡率、手术实施率.结果 循证组患者对本次护理服务的满意度显著比常规组高,差异有统计学意义(P<0.05);循证组腹痛消失时间、发热持续时间、平均住院时间、血淀粉酶、尿淀粉酶水平显著比常规组好,差异有统计学意义(P<0.05);循证组死亡率、手术实施率显著比常规组低,差异有统计学意义(P<0.05).结论 循证护理在重症急性胰腺炎护理当中的应用效果及对护理质量的影响大,可有效提高护理服务质量和患者满意度,加速血淀粉酶、尿淀粉酶水平降低和临床腹痛、发热等症状消失,有利于改善患者预后,降低手术实施率,缩短住院时间,值得推广应用.     

临床护理路径在子宫肌瘤围手术期的应用研究

目的:探讨临床护理路径(CNP)在子宫肌瘤围手术期的应用效果.方法:将我院子宫肌瘤患者60例随机分为观察组和对照组,对照组给予常规护理措施,观察组给予临床护理路径措施,评估两者护理效果.结果:观察组患者首次排气时间、首次下床时间、切口拆线时间及住院天数均短于对照组,2组比较差异具有统计学意义(P＜0.05).观察组患者并发症发生率、患者满意度及健康教育达标率均优于对照组,2组比较差异具有统计学意义 (P＜0.05).结论:临床护理路径在子宫肌瘤围手术期的应用效果明确,值得应用.     

急性胰腺炎患者行护理路径的临床效果观察

目的：观察急性胰腺炎患者行护理路径的临床应用效果。方法选取138例急性胰腺炎患者为研究资料,将其随机分为对照组和观察组,各69例。对照组给予常规护理,观察组给予护理路径护理,对2组患者的临床护理效果及护理满意度进行对比分析。结果观察组住院时间（8.11±2.72）d、住院费用（10100.2±344.9）元、并发症及不良反应发生率为1.45%、4.35%,均优于对照组的（10.4±2.94）d、（14257.3±317.7）元、并发症及不良反应发生率为11.59%、14.49%,2组比较差异具有统计学意义（P＜0.05）;观察组的患者满意度为98.55%,优于对照组的81.16%,差异具有统计学意义（P＜0.05）。结论给予急性胰腺炎患者护理路径护理,可以缩短住院时间,节约治疗费用,同时,可降低并发症及不良反应发生率,提高患者满意度,值得推广和应用。     

急性坏死性胰腺炎的围术期护理干预效果观察

目的观察急性坏死性胰腺炎的围术期护理干预效果。方法 2013年8月至2015年8月期间,通辽市医院收治的74例急性坏死性胰腺炎患者,根据围术期采用的护理方式,将所有的患者分为对照组(37例)和观察组(37例),给予对照组常规护理,观察组患者采用综合性护理干预,对两组患者护理后的临床效果进行评估。结果观察组患者治愈率、满意度均要高于对照组,住院时间、焦虑评分、抑郁评分明显低于对照组,差异具有统计学意义。结论针对急性坏死性胰腺炎患者,围术期给予患者综合性护理干预,能够增强手术效果,缩短治疗时间,值得借鉴。     

护理干预在急性重症胰腺炎患者围手术期的应用效果观察

目的:观察护理干预在急性重症胰腺炎患者围手术期的应用效果.方法:选择我院2015年10月-2016年12月收治的70例急性重症胰腺炎患者作为研究对象,通过随机数字表法将其分为对照组和观察组均35例,对照组给予围手术期常规护理,观察组给予围手术期护理干预,对比分析两组患者的临床指标、并发症发生率、护理满意度.结果:观察组临床指标、并发症发生率明显低于对照组、且护理满意度明显高于对照组,P<0.05.结论:急性重症胰腺炎患者围手术期实施护理干预,护理效果显著,既可改善临床指标、减少并发症发生率,又可提高护理满意度,值得临床推广应用.     

急性胰腺炎的循证护理及效果评价

目的：探讨分析循证护理在急性胰腺炎中的效果。方法选取该院收治的急性胰腺炎患者60例，按照随机数字分组法分为治疗组和对照组各30例，所有患者均给予基础对症治疗。对照组给予常规护理，治疗组给予循证护理。结果治疗组在腹痛缓解时间、胃肠功能恢复时间、血淀粉酶恢复正常时间、住院时间、并发症发生数量及死亡例数和患者满意度方面疗效均优于对照组，两组比较，差异有统计学意义（P〈0.05）。结论循证护理在急性胰腺炎应用中可以显著提高患者满意度，降低并发症的发生和死亡率，值得临床推广应用。     

循证护理在胆囊切除术围术期患者应用效果分析

目的 探讨循证护理在胆囊切除患者围手术期的应用效果.方法 选取2012年6月至2013年6月100例胆囊切除患者,随机分为观察组和对照组,每组50例.对照组采用常规护理方法,观察组在对照组基础上,采用循证护理的方法.比较两组患者手术效果及并发症情况.结果 观察组患者住院时间少于对照组,差异有统计学意义（P＜0.05）,并发症发生率低于对照组,差异有统计学意义（P＜0.05）,患者满意度高于对照组,差异有统计学意义（P＜0.05）.结论 应用循证护理可以降低胆囊切除患者的住院时间,有效控制并发症,提高患者的满意度,改善护患关系,提高护士专业理论水平.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.