揿针五脏背俞穴治疗慢性疲劳综合征的疗效研究

目的:观察揿针五脏背俞穴治疗慢性疲劳综合征(chronic fatigue syndrome,CFS)的临床疗效,为背俞穴单穴应用提供临床思路.方法:将患者随机分为双侧背俞穴组、单侧背俞穴组和背部非穴组,剔除脱落病例后每组均30例.双侧背俞穴组取双侧五脏背俞穴;单侧背俞穴组取单侧五脏背俞穴,左右交替施治;背部非穴组于五...     

从五脏俞作用机理谈五脏俞治疗失眠

通过对现代针灸临床文献的分析考察,五脏俞是脏腑之气输注于背腰部的腧穴,主治与其相应的脏腑、组织、器官疾病,而失眠与心、肝、脾、肾、胃、胆等脏腑组织密切相关,从中西医角度探讨了五脏俞的作用机理及其与失眠的关系。从而得出从五脏俞着手治疗失眠症可调整五脏所主功能从而起到安神定志、调和阴阳的目的。     

五脏俞透刺治疗慢性疲劳综合征的临床观察

目的观察五脏俞透刺治疗慢性疲劳综合征的疗效。方法将120例临床确诊慢性疲劳综合征的患者,随机分为五脏俞透刺组（60例）和常规针刺对照组（60例）,用相应方法针刺治疗30 d。结果采用五脏俞透刺组治疗后,患者疲劳症状积分明显减少,总有效率达95.00%,对照组总有效率为86.67%,明显好于常规针刺对照组,（P〈0.05）。结论五脏俞透刺是治疗慢性疲劳综合征的有效方法,有较好的临床疗效。     

针刺五脏背俞穴的临床体会

目的：评价针刺五脏背俞穴治疗相应脏腑疾病的临床应用。方法：选用临床有代表性的病例,通过辨证选用相对应的背俞穴进行针刺操作。结果：采用针刺背俞穴法的病例都达到了临床治愈的标准。结论：针刺背俞穴对于治疗相应五脏的病变具有较好的疗效,背俞穴相互配合应用,能够调整相应的脏腑阴阳的机理。     

针刺膀胱经五脏俞治疗围绝经期综合征的临床研究

目的：观察针刺膀胱经五脏俞用于治疗围绝经期综合征的临床效果。方法：选择该院在2015年3月至10月收治的围绝经期综合征患者100例,随机分为实验组和对照组患者各50例,实验组选择针刺膀胱经五脏俞治疗,对照组采用口服贝美力片药物治疗,观察两组患者的治疗效果。结果：实验组的治疗效果明显好于对照组患者（P ＜0.05）。结论：在围绝经期综合征采用针刺膀胱经五脏俞治疗发挥了很好的效果,好于口服药物治疗,可比在临床治疗中推广和应用。     

俞募配穴在临床中的应用(五脏篇)

背俞穴在临床上主要是诊察和治疗与其相应的五脏疾患,募穴多用于治疗腑病,背俞穴与其相应的募穴联用称俞募配穴.俞募配穴法充分体现了经络的调节阴阳作用,对治疗阴证阳证俱见的脏腑病症疗效显著.论述五脏俞募相配的作用和主要治疗范围,望对研究和临床治疗提供参考.     

俞募穴与脏腑相关

本文主要探讨了俞募穴与脏腑的相关性。从大量的古今名家病例和医案中发现俞募穴与五脏六腑的的关系非常的密切。尤其是俞穴与五脏之间；募穴与六腑之间的关系更密切。俞募穴不但能治疗疾病而且还能诊断疾病。     

黄芪注射液五脏俞穴位注射对CFS的临床疗效观察

目的探究黄芪注射液五脏俞穴位注射对CFS的临床疗效。方法选取本院收治的65例慢性疲劳综合征患者作为观察对象,并将所有患者随机分为治疗组32例,对照组33例,对照组给予常规的肌肉注射,而治疗组则采用黄芪注射液五脏俞穴位注射的方法,对两组的治疗效果进行对比。结果经过治疗后两组患者的FS-14总分间的差异具有显著性,且治疗组的疗效明显优于对照组,组间差异具有显著性(P0.05)。结论对于CFS患者给予黄芪注射液五脏俞穴位注射能够收到显著的效果,值得在临床中推广应用。     

从五脏相关谈五脏俞治疗失眠

从“五脏相关”理论角度看,失眠病位在心,但与肝脾肺肾密切相关,五脏功能失调是导致失眠发生的主要病机。五脏俞是五脏之气输注于背腰部的腧穴,通过膀胱经的联络作用,与五脏经气相通,为五脏之气转输流注于全身的枢纽,与五脏之功能紧密相关,调五脏之背俞穴可调整五脏所秉权之功能而使机体达到阴平阳秘、精神内守、气血调和之目的。从五脏相关论就五脏俞治疗失眠的理论、临床及机理研究作了系统论述。     

针刺五脏俞联合康复训练治疗脑血管意外后偏瘫临床研究

目的研究治疗出现脑血管意外后发生偏瘫患者过程中应用针刺五脏俞联合康复训练的临床效果。方法选取2016年1月至2018年12月间我院收治的60例脑血管意外后偏瘫患者,随机将患者分成两组,各30例,其中对照组为药物治疗联合康复训练治疗,观察组为针刺五脏俞联合康复训练,并将两组患者NIHSS评分与OHS评分结果进行比较。结果治疗前,两组患者NIHSS评分、OHS评分比较后,差异不明显(P0.05);治疗后,观察组NIHSS评分、OHS评分均低于对照组,差异显著(P0.05)。结论在治疗脑血管意外后偏瘫患者过程中应用针刺五脏俞联合康复训练的临床效果明显。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.