术前螺旋CT检查对判断胃癌可切除性的意义

目的：探讨术前螺旋CT检查对于胃癌可切除性的意义。方法：将术前螺旋CT所显示胃壁厚度,胃周围脂肪间隙及胃周淋巴结影情况与手术中探查情况及手术切除结果进行回顾性分析。结果：在96例胃癌患者中,进行手术切除患者88例,总切除率为91.6%。当CT显示胃壁增厚,胃周脂肪间隙清晰,不论周围是否存在淋巴结影,可考虑进行手术切除。当胃周脂肪间隙消失,伴有或不伴有腹水出现时,应考虑进行新辅助化疗,根据病变缓解情况,考虑二期手术治疗。结论：术前进行螺旋CT检查对于肿瘤手术可切除性判断有重要意义。     

螺旋CT动态增强扫描及血管成像在胰腺癌术前评估中的价值

目的 探讨螺旋CT动态增强扫描及血管成像在胰腺癌术前评估中的价值.方法 45例胰腺癌患者接受螺旋CT动态增强扫描及血管成像检查,根据检查结果进行肿瘤分期和可切除性判断,并将其与术中探查结果进行对比.结果 45例患者中,27例患者接受手术治疗,其中22例术前CT评估为可切除,实际成功切除17例,阳性预测值为77%;5例术前CT评估为不可切除,手术探查均不能切除.肿瘤部位、肝脏转移和淋巴结转移方面,术前CTA评估与术中探查结果一致.结论 螺旋CT动态增强扫描及血管成像可直观显示肿瘤与周围组织结构的关系及血管受侵情况,在胰腺癌术前肿瘤分期和可切除性评估方面具有较高价值.     

食管、胃肿瘤螺旋CT检查探讨

 目的 探讨食管、胃肿瘤的CT检查方法及对术前临床分期的指导意义。方法 60例患者，其中食管癌 25例，贲门癌 15例，胃癌 20例，均经手术病理证实，采用低张充水法行螺旋CT扫描。结果 60例患者CT检查可清楚显示病变区食管壁、胃壁增厚，管腔狭窄，轮廓改变以及病变向管腔外浸润程度及周围器官、淋巴结转移情况。结论 低张充水法螺旋CT扫描，可以清楚显示食管癌、胃癌向管壁内外浸润的程度，对术前肿瘤分期及治疗方案选择有重要指导意义。     

64排螺旋CT多期增强扫描对进展期胃癌术前评估的价值

目的探讨64排螺旋CT三期增强扫描对进展期胃癌术前评估中的价值。方法选择CT检查前已确诊为胃癌的患者80例,术前行64排螺旋CT三期增强扫描,然后进行病理分期TNM分期,分析螺旋CT与病理分期的效果,并且探讨增强CT对于手术判断的效果。结果CT影像学主要表现为胃壁异常增厚、肿瘤向周围直接侵犯、局部和远处淋巴结转移,CT与病理诊断对比在T分期与N分期上有显著性差异（P〈0．05）,而对M分期对比上无明显差异（P〉0．05）。CT预测治疗方式与临床相符合的敏感度为78．6％,特异性为86．5％,准确率为83．8％。结论多层螺旋CT（MSCT）可较准确地显示胃癌侵犯胃壁的深度、淋巴结转移和远处脏器的转移情况,在胃癌M分期判断上有较高的准确率,能为手术治疗方案选择提供参考。     

128层螺旋CT对胃癌可切除状况的评估价值

目的探讨128层螺旋CT对胃癌可切除状况的评估价值。方法选择诊治的胃癌患者120例作为研究对象,所有患者都给予128层螺旋CT检查,评估胃癌可切除性并记录影像学特征。结果在120例患者中,螺旋CT诊断为Ⅰ期66例、Ⅱ期24例、Ⅲ期18例、Ⅳ期12例,与病理分期有较好的一致性,临床分期诊断准确率为95.0%。CT评价胃癌可切除68例,实际采用手术切除治疗65例,CT对胃癌可切除状况的评估敏感性、特异性分别为98.5%和98.1%。全胃切除35例,胃部分切除30例,都顺利完成手术,围手术期无严重并发症发生。结论128层螺旋CT在胃癌中的应用可准确判断临床分期,具有很好的影像学特征,有利于指导与评估手术切除治疗。     

CT对胃癌的诊断价值及应用限度

目的探讨螺旋CT对胃癌的诊断价值及应用限度。方法回顾性分析38例经病理检查确诊的胃癌患者的螺旋CT检查表现。结果 0例肿瘤累及胃浆膜层,8例肿瘤突破胃浆膜层,10例肿瘤向外侵犯并发生转移。结论螺旋CT检查可显示胃癌肿块大小、形态,肿瘤与周围组织的关系及淋巴结转移情况,对胃癌的术前分期评估及治疗方法的选择具有重要意义。     

螺旋CT增强扫描对进展期胃癌胃周淋巴结转移的研究

目的探讨螺旋CT增强扫描在判定进展期胃癌胃周淋巴结性质上的应用价值.方法应用螺旋CT增强扫描方法对56例进展期胃癌的胃周淋巴结的直径、形态类型等影像特征进行观察,并与术后病理诊断对照,明确与进展期胃癌胃周淋巴结转移相关的生物学行为因素.结果支持以直径9mm作为螺旋CT增强扫描诊断胃周淋巴结转移的直径标准(P＜0.05).多种胃癌生物学行为CT影像特征与癌肿对应淋巴结转移率密切相关(P＜0.05).结论应用螺旋CT增强扫描检查对进展期胃癌的胃周淋巴结性质进行判断,手术方式的确定和综合治疗具有重要意义.     

直径不超过2 cm周围型非小细胞肺癌的临床病理特征、手术方式及预后

背景与目的:随着CT扫描技术应用逐渐普及,对于直径不超过2 cm的周围型非小细胞肺癌(NSCLC)的检出率也逐渐提高.本研究通过对周围型小NSCLC的临床病理特征以及患者生存期的分析,试图探讨最佳的手术方式.方法:回顾性分析2000年1月-2001年7月手术切除的直径≤2 cm的周围型小肺癌75例.对手术切除方式(肺叶切除加淋巴结清扫或局部切除)、淋巴结转移情况、胸部cT影像学表现以及患者生存期与肿块大小进行比较分析.结果:接受肺叶切除加淋巴结清扫者57例,接受局部切除者18例.病灶在>1.5～≤2.0 cm者淋巴结转移率为14.63%,病灶在>1.0～≤1.5 cm者淋巴结转移率为14.81%,两组间差异无显著性(P=0.10).病灶≤1.0 cm者均未见淋巴结转移.无淋巴结转移和伴有淋巴结转移者的5年生存率分别为92.31%和60.0%(P=0.000).12例CT显示为磨玻璃影(GGO)表现者均未见有淋巴结转移,5年生存率为91.67%.结论:即使是≤2 cm的病灶仍可伴有纵隔和肺门淋巴结转移,手术切除方法宜采用肺叶切除加淋巴结清扫.但对于≤1.0 cm的病灶,尤其在高分辨CT上显示有GGO改变的病灶,可考虑行局部切除,而无需行淋巴结清扫.     

胃癌和胃淋巴瘤的CT表现对比分析

背景与目的:进展期胃癌与胃淋巴瘤的CT表现在鉴别诊断上较困难,均可表现为胃壁增厚、腔内肿块、胃腔狭窄、淋巴结肿大、远处脏器转移等。本研究通过对比胃癌与胃淋巴瘤的CT表现差异,以提高对胃肿瘤,特别是胃淋巴瘤的CT诊断水平。方法:回顾性分析27例进展期胃癌和25例胃淋巴瘤患者的CT表现,观察病变部位、病变大体形态、胃周径侵犯范围、病灶的最大厚度、粘膜是否光整、粘膜皱襞是否增厚、浆膜受侵情况、有无坏死、病变强化程度、强化是否均匀、其他器官受累情况、腹部淋巴结情况。结果:23例(85.2%)胃癌近胃腔表面见"白线"征,门静脉期"白线"区范围较动脉期大;所有胃淋巴瘤患者均未见"白线"征。13例(48.1%)胃癌非"白线"区门静脉期强化程度高于动脉期。所有胃癌患者胃壁侵犯范围均<50%,23例(85.2%)胃淋巴瘤患者胃壁侵犯范围>75%。所有27例(100%)胃癌患者均见胃粘膜溃疡,1例(4%)胃淋巴瘤见胃粘膜溃疡。11例(44.0%)胃淋巴瘤有2个区或以上的胃周淋巴结肿大,8例(32.0%)胃淋巴瘤患者有肾门下腹膜后淋巴结肿大;所有胃癌患者均未见2个区或以上胃周肿大淋巴结,亦未见肾门下腹膜后淋巴结肿大。结论:胃癌与胃淋巴瘤的CT表现各有其特点,包括有无胃粘膜"白线"征、粘膜溃疡、胃壁侵犯范围、胃周肿大淋巴结分布、有无肾门下腹膜后肿大淋巴结等,这些特点对于二者的鉴别诊断具有一定的参考价值。     

术前低张力水充盈胃薄层CT扫描30例进展期胃癌诊断的临床价值分析

[目的]探讨术前低张力水充盈胃薄层CT扫描在进展期胃癌中的临床价值。[方法]30例进展期胃癌术前行低张力水充盈胃薄层CT扫描,并与术后病理对照分析。[结果]30例CT扫描示胃壁厚度5～25mm,术后病理为8～28mm。CT检查15例淋巴结转移,术后病理18例淋巴结转移。术后证实6例周围脏器侵犯,CT准确率为85.7%。[结论]低张力水充盈胃薄层CT扫描可了解病变的侵犯范围及转移情况,对确定肿瘤分期、提供治疗方案起重要的作用。     

CT检查在胃癌诊疗中的价值(附126例分析)

目的：研究ＣＴ检查在胃癌诊疗中的价值。方法：对１２６例胃癌患者进行了术前低张水充盈ＣＴ动态扫描，并和手术标本、术后病理检查对照研究。结果：胃癌术前ＣＴ检出率１００％，分期准确率６１．９％，胃癌根治性手术切除术前ＣＴ阳性预测值９１．６％，阴性预测值７１．０％。结论：对胃癌患者术前进行动态ＣＴ检查是必要的，在范围及深度上可弥补胃镜的不足，有助于胃癌的诊断与治疗方案的确定。     

53例胃癌CT影像检查与手术病理对照研究

目的：研究CT检查对胃癌诊治的价值。方法：从1995年9月到1996年8月，对53例胃癌患者进行了术前低张水充盈CT动态扫描，并和术后病理检查对照研究。结果：53例对照研究表明，胃癌术前CT检出率100％，胃癌术前CT分期准确率60．3％，胃癌可行根治性手术切除术前CT估价的准确性88．24％，难以根治性手术切除术前CT估价的准确性57．89％。结论：对胃癌患者术前进行动态CT检查是必要的，在范围及深度等定位诊断上可弥补胃镜的不足，有助于胃癌的诊断与治疗。     

多排螺旋CT低张力动态增强扫描在进展期胃癌术前评估中的价值

目的 探讨多排螺旋CT（MDCT）低张力动态增强扫描对进展期胃癌术前评估的价值.方法 对43例进展期胃癌患者行MDCT低张力动态增强扫描,判断肿瘤诊断及分期,预测手术可切除性,并与病理学结果进行比较.结果 本组43例行手术治疗,其中36例行手术切除,7例行肠胃吻合术.MDCT术前T分期总体符合率为76.7％（33/43）,术前N分期总体符合率为74.4％（32/43）.胃壁厚度与浆膜浸润密切相关（x 2=20.1709,P＜ 0.001）.结论 MDCT低张力动态增强扫描能够较全面、准确地反应进展期胃癌T、N分期,能够为胃癌术前诊断和治疗提供指导.     

原发性胃恶性淋巴瘤28例临床分析

目的 探讨原发性胃恶性淋巴瘤的临床特点、诊断方法、外科治疗方法.方法 回顾性分析经手术治疗的28例原发性胃恶性淋巴瘤的临床资料.术前常规行胃镜、X线钡餐造影、CT检查.对早期伴有出血、穿孔或化疗期间有出血、穿孔风险及胃镜病理诊断疑癌的患者采取手术治疗.结果 术式:D1根治术13例,D2根治术11例,姑息切除术3例,联合...     

胃癌患者术前胃镜活检与外科术后病理的对比研究

目的:探讨胃癌患者术前胃镜活检与外科术后病理对比情况。方法:76例可疑胃癌患者为研究对象。所有患者术前均经胃镜活检诊断,术后均外科病理检查,对比两者在诊断符合率上情况。结果:诊断结果,术前胃镜活检确诊胃癌84.21%,疑似胃癌11.84%,排除胃癌3.95%;术后病理诊断确诊胃癌94.74%,疑似胃癌0,排除胃癌5.26%。病理结果,术前胃镜活检管状腺癌、黏液腺癌、乳头状腺癌、印戒细胞癌发生率分别为9.21%、38.16%、44.74%、7.89%;术后病理诊断管状腺癌、黏液腺癌、乳头状腺癌、印戒细胞癌发生率分别为19.44%、29.17%、23.61%、27.78%。分化程度,术前胃镜活检分化型占59.21%,分化不良型占40.79%;术后病理诊断分化型占80.56%,分化不良型占19.44%。以上两者比较差异均有统计学意义（P<0.05）。结论:虽然胃镜活检和术后病理不完全一致,但作为术前一种诊断,胃镜活检准确度仍较高。     

Surgical treatment of concurrent cancer of the esophagus and stomach

Out of a total of 250 resections for carcinoma of the esophagus done in our department between 1965 and 1983, there were 11 patients with a concurrent esophageal cancer, nine being gastric cancer and seven of them early gastric cancer. In these nine, four underwent resection of the esophagus and lesser curvature of the stomach with gastric tube reconstruction. Two of the four patients are alive 10 and 3 yr postoperatively. We hold the view that detailed preoperative gastric examination is most important to plan the surgical repair and that the small gastric tube may serve as a substitute by resecting the lesser curvature of the stomach in cases of early proximal gastric cancer.     

A case of gastric cancer with paraaortic lymph node metastasis responding to TS-1/CDDP combination therapy

A 53-year-old man had consulted another physician regarding his epigastralgia and anorexia. Since gastric cancer was detected, he was referred to our department. An upper gastrointestinal endoscopy revealed a type-2 gastric cancer at the upper portion of the lesser curvature of the stomach, and an abdominal CT scan showed marked swelling of periaortic lymph nodes. Since a radical resection appeared impossible, we used preoperative chemotherapy with a combination of TS-1 and CDDP. The patient was administered TS-1 for 3 weeks at 120 mg/ day, received an intravenous drip infusion of 90 mg/body of CDDP on day 8, and then discontinued chemotherapy for 2 weeks, which was regarded as one course. After 2 courses of the chemotherapy, an upper gastrointestinal endoscopy showed that the primary tumor was reduced in size, the periphery of the tumor almost flattened, and an abdominal CT scan confirmed the loss of swelling in the periaortic lymph nodes. The responsive rate was evaluated as PR. Since a radical resection was considered possible, we performed a total gastrectomy with complete D3 extirpation combined with a splenectomy. Histological efficacy was evaluated as grade 2 in primary cancer, and grade 3 in lymph nodes. Regrettably, the patient died one year and 7 months postoperatively. However, we consider the TS-1 and CDDP in combination useful as preoperative chemotherapy for advanced gastric cancer with periaortic lymph node involvement.     

Role of endoscopic clipping for determining the resection line for tumors located in the middle or upper corpus of the stomach: experience with 100 gastrectomies for early gastric cancer

BACKGROUND: The efficacy and limitations of preoperative endoscopic clipping for determining the resection line in patients with early gastric cancer remain unclear. MATERIALS AND METHODS: Subjects comprised 100 patients with early gastric cancer (33 females, 67 males; mean age, 60.5 years; range, 33-84 years) who underwent pre-operative endoscopic clipping for lesions located in the middle or upper corpus of the stomach. The results of endoscopic clipping for a selection of appropriate surgical procedures were investigated. RESULTS: Distal gastrectomy was performed in 94 patients, the mean length between the lesion and proximal surgical margin of the resected stomach being 28.9 +/- 18.0 mm (mean +/- SD). The surgical margin was eventually free of tumor in all patients. In 5 patients, clips were considered to be placed inadequately, and all 5 tumors were macroscopically depressed or flat and > 40 mm in size. CONCLUSION: Pre-operative endoscopic clipping represents a safe and reliable procedure to determine the resection line for tumors located in the middle or upper corpus of the stomach for treatment of early gastric cancer. During surgical resection, frozen section examination of the proximal cut end is recommended for patients with tumors that are macroscopically depressed or flat and > 40 mm in size, or that display a macroscopically unclear proximal margin.