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目的建立用于测试颅内支架性能的颈内动脉虹吸段动物模型。方法使用快速原型及脱蜡技术建立6只颈内动脉虹吸段约束装置。手术暴露并游离6只犬双侧颈总动脉。左侧颈总动脉近端暂时性夹闭,远端结扎并沿结扎点近侧切断。右侧颈总动脉远端暂时性夹闭,近端结扎并沿结扎点远侧切断。左侧颈总动脉近侧段穿过塑型装置,并与右侧颈总动脉远侧游离段端端吻合。术后1、2周、1个月血管造影,视觉评估虹吸段模型形态,血管通畅,吻合口狭窄及附壁血栓形成情况。结果所有实验犬均能耐受手术,无一只死亡或出现神经功能障碍。建模平均手术时间90min。术后1、2周、1个月血管造影,显示虹吸段模型空间结构与其人体原形高度相似,2例发生吻合口狭窄,1例吻合口附壁血栓形成。所有模型虹吸段随访中均保持通畅。结论采用体外约束装置,手术建立虹吸段模型切实可行,该模型具有高度可重复性、可靠性,可用于测试神经血管内材料。 相似文献
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目的:探讨将血管内支架置于动脉瘤附近载瘤动脉后发生的血流动力学改变,为动脉瘤的载瘤动脉内支架治疗提供实验依据。材料与方法:向6只犬7个颈总动脉侧壁动脉瘤附近载瘤动脉内置入血管内支架,而后作血管造影,比较支架置入前后瘤胚闭褰主载瘤动脉通畅情况。结果:7个动脉瘤载瘤动脉内支架置入后3天瘤腔均发生闭塞,载瘤动脉保持通畅;3周后瘤腔仍见闭塞且载瘤动脉保持通畅。结论:向动脉瘤附近载瘤动脉内置入血压管内支架。 相似文献
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目的;探讨将一侧颈外静脉与双侧颈总动脉吻合建立侧壁动脉瘤的可行性。材料与方法:对10只犬应用显微外科技术进行颈外静脉、颈总动脉端侧吻合,作血管造影证实瘤腔存在及载瘤动脉通畅。结果:10只犬均成功地建成颈总动脉侧壁动脉瘤,其中8例为宽颈动脉瘤。结论:应用犬一侧颈外静脉与双侧颈总动脉吻合建立双侧颈总动脉动脉瘤特别是宽颈动脉瘤切实可行。 相似文献
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MRA评价颈总动脉分叉的正常解剖及其变异 总被引:1,自引:0,他引:1
目的:研究颈总动脉分叉(CCAB)的正常影像学解剖及其变异。材料与方法:用GE Signa1.5T MR机对73例行CCAB MRA检查。分别测量CCAB最大角度、分叉高度及颈内动脉(ICA)与颈外动脉(ECA)的相对位置关系。结果:80.6%的CCAB角度在20 ̄40°之间;60.6%两侧CCAB高度在同一水平,39.4%不在同一水平,相差最大18mm;74.3%ICA起始段居ECA后外侧,其中 相似文献
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1mm内径涤纶小血管桥接大鼠颈总动脉的实验研究 总被引:1,自引:0,他引:1
采用48只SD雄性大鼠,切除7mm一段左颈总动脉,以10mm长、1.0mm内径的涤纶小血管桥接之.术后24、72小时及1、2、3、4、8和12周分别以多普勒超声监测血流通畅情况.每次随访时,对5例通畅者(8周时3例,12周时4例)及所有不通畅者行手术探查或血管造影检查,以进一步证实多普勒检查结果的正确性,同时取下桥接血管.部分桥接血管经处理后作扫描电镜检查.结果显示桥接后12周的累积通畅率为77.1%.快速而完全的内皮化过程在桥接后3周即完成,形成一光滑的内皮细胞层.11例桥接血管因血栓形成而失败,其中10例发生在桥接后3周之内,即内皮化之前.提示涤纶小血管可成功地用于大鼠颈总动脉桥接,失败主要发生在内皮化之前,其原因为血栓形成,若用抗凝药物或内皮细胞种植防止早期血栓形成,可望进一步提高通畅率,有可能使其成功地用于临床. 相似文献
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目的:从组织病理学角度研究血管内支架置于动脉瘤附近载瘤动脉闭塞动脉斩作用机制。材料与方法:对7个动瘤动脉内置入支架后3天,1周、3周动脉瘤及载瘤动脉取材,观察其组织病理学改变。结果:支架置入后瘤腔完全被血栓充填,且血栓质地由软变硬,最后与壁连为一体,支架表面纤维肌样组织覆盖。结论:将血管内支架置于动脉胶附近载瘤动脉,可同时促使瘤腔内形成血栓而闭塞动脉瘤 相似文献
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兔颈总动脉侧壁型动脉瘤模型制作的改进 总被引:2,自引:0,他引:2
目的 对兔颈总动脉侧壁型动脉瘤模型进行改进,以评价建模的成功率及支架植入后颈总动脉的通畅率.方法 取新西兰大白兔20只,饲养1周后行左侧颈内动脉结扎.1个月后行颈部3.0 TMRA检查评价颈动脉与椎动脉的变化情况.采用间断式外翻缝合法吻合静脉囊与颈总动脉,建立侧壁型动脉瘤.在植入覆膜支架前、术后即刻、3个月、6个月行血管造影.结果 20只实验兔均顺利行左侧颈内动脉结扎.MRI示结扎前右颈总动脉中段平均直径为(2.35±0.08) mm,结扎后1个月右颈总动脉中段平均直径为(2.89±0.22) mm,与术前比较差异有显著统计学意义(P<0.01).MRA示17只兔右颈总动脉明显增粗,而双侧椎动脉略增粗;3只兔颈总动脉增粗不明显,而双侧椎动脉明显增粗.建立兔颈总动脉囊状动脉瘤模型17只,术后均健康成活.DSA示覆膜支架植入前所有动脉瘤及右颈总动脉通畅,4个动脉瘤腔内有少量血栓形成,但无自发性完全闭塞.Willis或镁合金覆膜支架植入术后即刻造影示动脉瘤闭塞,右颈内动脉通畅.术后3个月DSA示16只兔右颈内动脉通畅,1只闭塞.术后6个月DSA示16只兔右颈内动脉通畅.动脉瘤模型的成功率为100% (17/17),覆膜支架植入后右颈总动脉的通畅率为94.1%(16/17).结论 兔颈总动脉侧壁型动脉瘤模型制作的改进提高了动脉瘤模型的成功率及覆膜支架植入后右颈总动脉的通畅率. 相似文献
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Summary The angiographic appearance of a duplicated internal carotid artery is described. 相似文献
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Summary A rare case of anomalous origin of the posterior meningeal artery from the internal carotid artery, normally arising from the vertebral artery, is presented. 相似文献
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Colour Doppler sonography allowed noninvasive confirmation of bilateral common carotid artery dissection in a patient with previous aortic dissection. It also cast light on the pathophysiology. 相似文献
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Yuma Hiratsuka Hideki Endo Naoyasu Okamura Masaaki Mikamoto Bunsho Asayama Kenji Kamiyama Toshiaki Osato Hirohiko Nakamura 《Radiology Case Reports》2022,17(5):1770
Agenesis of the left common carotid artery with separate origins of the left internal and external carotid arteries from the aorta is an extremely rare anomaly. This anomaly is typically asymptomatic unless associated with other conditions. We report a case of separate origins of the left internal and external carotid arteries from the aorta in a patient with intracerebral hemorrhage. A 42-year-old man was transferred to our hospital by ambulance because of left hemiparesis. Computed tomography scan revealed right putaminal hemorrhage. Computed tomography angiography and digital subtraction angiography demonstrated independent origins of the left internal carotid artery and external carotid artery from the aortic arch. Right internal carotid angiography revealed blood supply to the left anterior cerebral artery and middle cerebral artery via the anterior communicating artery. The separate origins of the left internal and external carotid arteries from the aorta may cause hemodynamic stress to the contralateral side, leading to right intracerebral hemorrhage. 相似文献
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目的探讨建立犬颈动脉分叉部动脉瘤模型的可行性。方法建立18只犬新的颈总动脉(CCA)分叉部动脉瘤模型,随机分为分叉部顶端弹性蛋白酶处理组(实验组,n=9)和生理盐水处理组(对照组,n=9)。术后即刻、12周和24周分别行血管造影观察动脉瘤顶端形态变化,术后12周和24周分别行组织病理学分析。结果血管造影显示实验组中5只模型动脉分叉顶部观察到新生动脉瘤形成,平均直径(3.2±0.4)mm,对照组中所有模型分叉部顶端均未观察到有新生动脉瘤形成。实验组中新生动脉瘤在随访过程中未见到动脉瘤破裂。组织病理学分析显示实验组中分叉部顶端动脉瘤表现为内弹力膜不连续、弹力纤维断裂、肌层变薄、平滑肌细胞减少(与对照组相比,P<0.001)。结论犬重建颈动脉分叉顶端经弹力酶消化所致动脉壁退化可引起新生动脉瘤形成。 相似文献
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Background and purpose
Internal carotid artery (ICA) large or giant saccular aneurysms is challenging for endovascular coil embolization and surgical clipping with a high recanalization and rebleeding rate. We report our results using Onyx in the endovascular treatment of ICA large or giant saccular aneurysms.Methods
During 2008–2010, 5 patients with 5 large or giant saccular aneurysms in ICA were treated with a liquid embolic agent (Onyx; Micro Therapeutics, Irvine, CA). One aneurysm was small (<10 mm), 2 were large (≥10 mm, <25 mm) and 2 were giant saccular aneurysms (≥25 mm). Of 3 female and 2 male patients, 3 were incidental and 2 had bleeding. Selective embolization was performed with Onyx alone or a combination with coils. Clinical and anatomic outcomes were assessed with the Modified Glasgow Outcome Scale and follow-up angiography was performed at 4–21 months (mean 12.2 months).Results
Complete aneurysm occlusion was obtained in all of the aneurysms on immediate control angiogram. There was not any procedure-related complication. No recanalization was observed at the follow- up periods. There were 2 ICA occlusions in giant ICA aneurysms. The 5 patients were all clinically asymptomatic at follow-up.Conclusion
Endovascular embolization with Onyx is a useful treatment for ICA large or giant aneurysms, which is unsuitable for coiling or surgical treatment. 相似文献17.
Background and purpose
Hyperintense vessels (HV) on fluid-attenuated inversion recovery (FLAIR) images were assumed to be explained by slow antegrade or retrograde leptomeningeal collateral flow related to extracranial or intracranial artery steno-occlusion. The aim of this study was to investigate the effect of recanalization after endovascular therapy of symptomatic internal carotid artery (ICA) occlusion on the presence of HV.Methods
Eleven patients with symptomatic ICA occlusion were retrospectively enrolled. Changes in the HV on FLAIR images were examined in affected hemisphere of each patient after successful treatment with endovascular recanalization (angioplasty, n = 3; stent-assisted angioplasty, n = 8). The relationship between postoperative changes in the HV and Thrombolysis In Cerebral Ischemia (TICI) scale (I-III) was assessed.Results
After operation, HV of the 11 affected hemispheres were showed to be decreased (n = 3) or disappeared (n = 8) in treated side. The median interval between pre- and postoperative MRI examinations was 97.0 h (range, from 69. to 48.7 h). Of the 8 patients with disappeared HV, 7 achieved high TICI grade flow (III) and 1 had relatively low TICI grade flow (IIc) in treated side. However, all the 3 patients with decreased HV were found to be relatively low TICI grade flow (IIc).Conclusion
Our data indicate that endovascular recanalization of ICA occlusion was effective for decreasing HV. Postoperative decrease in HV can be considered as a marker for hemodynamic improvement. 相似文献18.
Summary The occurrence of an aneurysm, 2x2.5 cm in size, in the intrapetrosal portion of the internal carotid artery in a 24-year-old female patient, during the course of herpes zoster ophthalmicus, is described. 相似文献