睫状体血管平滑肌瘤一例

睫状体部位的肿瘤比较少见，其中平滑肌瘤仅有少数个案报告，术前常难以确诊，多数被拟诊为恶性黑色素瘤，术后组织病理学检查才能确诊为良性平滑肌瘤。睫状体血管平滑肌瘤报告极少。笔者对我院收治的组织病理学确诊的1例睫状体血管平滑肌瘤进行分析，探讨该肿瘤的临床与组织病理学特点。     

眼部血管内皮瘤的诊断和治疗

血管内皮瘤是一种主要发生于全身软组织、肝、肺、骨等部位罕见的交界性或低度恶性血管源性肿瘤,一般呈浸润性生长,偶尔也会出现转移。眼部血管内皮瘤为一种更为罕见的血管瘤类型,目前尚缺乏针对其良恶性的定位及统一的诊疗指南。眼部血管内皮瘤多原发于眼眶,也可原发于眼睑及泪器。临床表现为眼睑肿胀、眼球突出,影像学检查常显示肿瘤局部浸...     

虹膜平滑肌瘤1例

1临床资料患者,女,28岁,2005年1月10日因左眼胀痛伴视力下降0·5a入院。专科检查:左眼视力0·1/0·08(均不能矫正),左眼压13mmHg(1kPa=7·5mmHg),结膜无充血,角膜透明,前房角颞下方窄Ⅲ,其余为宽角;下方虹膜色素脱落,瞳孔直径约4mm,光反应灵敏,颞侧虹膜后方可见棕色隆起,约占瞳孔1/2,表面光滑,扩瞳后隆起向下方延伸,外观分别为2mm×3mm×3mm,2mm×2mm×2mm及3mm×3mm×2·5mm的棕黑色球状物,表面光滑,无结节及新生血管;晶状体轻度混浊,余未见异常。右眼未见异常。血常规、肝脾B超、胸片正常。UBM示:颞侧瞳孔区紧贴晶状体,虹膜后方可见椭…     

睫状体平滑肌瘤二例

睫状体平滑肌瘤二例林锦镛于士柱李恩江例１女，１３岁。因右眼视力下降及眼球胀感半年，近２０天视力丧失，于１９９１年５月１０日来我院诊治。体检未见异常。眼部检查：视力：右眼光感，左眼１．２。右眼球颞下方巩膜呈局限性葡萄肿样改变。右眼视网膜全部脱离，颞侧睫...     

睫状体平滑肌瘤三例

睫状体平滑肌瘤是少见的眼内肿瘤，不易与睫状体部位的其他肿瘤（无色素性的黑色素瘤、神经鞘瘤、神经纤维瘤等）相鉴别，临床常用的辅助检查如超声波、ＣＴ、磁共振成像及眼底荧光素血管造影等对此无特征性诊断意义［１］。现将我们收治的３例睫状体平滑肌瘤患者报告如下...     

脉络膜平滑肌瘤一例

1 病例报告 患者,女,36岁,因右眼视力下降4个月余,于1998年2月10日来我院诊治。全身体检未见异常。眼部检查:右眼视力0.1,右晶状体后囊及玻璃体轻度混浊,右眼底颞侧见灰棕色半球形隆起。彩色多普勒超声显像,右眼球内颞侧见     

脉络膜平滑肌瘤一例

眼部平滑肌瘤国内外均十分少见 ,多发于眼眶 ,而发生在脉络膜的平滑肌瘤 ,更是罕见。因其临床表现及影像学特征 ,与发生在脉络膜部位的其他肿瘤如黑色素瘤有许多相同之处 ,临床上较难鉴别 ,影响治疗方案的选择 ,现报告如下。患者女 ,37岁。因右眼视力下降 6个月入院。入院后全身检查情况良好。眼科情况 :右眼视力 0 .0 4,眼压 13.4mm Hg( 1mm Hg=0 .133k Pa) ,眼前节未见异常。左眼视力 1.0 ,内外眼无异常。 0 .5 %复方托品酰胺散瞳后见右眼黄斑颞侧 7:0 0～10 :0 0钟处有 6 DD× 6 DD的半球形肿块 ,呈灰黄色 ,边界清楚 ,表面有血管爬行 …     

睫状体平滑肌瘤二例

睫状体平滑肌瘤是眼内良性肿瘤 ,因其临床表现及影像学特征 ,与发生于睫状体部位的其他肿瘤如黑色素瘤有许多相同之处 ,因此在临床上难以鉴别 ,影响治疗方案的选择。现将我院遇到的 2例睫状体平滑肌瘤报告如下。例 1　女 ,4 4岁。因右眼胀痛 1年 ,视物遮挡 2个月 ,于2 0 0 0年 2月收入院。眼部检查 :右眼视力 0 2 ,左眼视力 0 7。眼压 :右眼 17 3 7ｍｍＨｇ( 1ｍｍＨｇ =0 13 3ｋＰａ) ,左眼 14 74ｍｍＨｇ。右眼巩膜表面无血管扩张 ,角膜透明 ,前房深浅正常 ,虹膜纹理清晰 ,房角镜检查未见异常。左眼正常。散瞳 :右眼颞侧 7～ 10点钟处…     

虹膜平滑肌瘤一例

患者男，62岁。因左眼视力渐进性下降2年，加重1个月。于2001年3月以虹膜肿物、并发性白内障收入我院。眼部检查：视力右眼1.2，左眼眼前1m指数。右眼正常。左眼上睑轻度下垂，结膜颞下方轻度充血，角膜透明，前房颞下方消失，该处角膜内皮与虹膜前表面相接，余前房深度正常，房水闪光（-）。瞳孔欠圆，直径约3mm，对光反应存在。瞳     

Angioleiomyoma of the Ciliary Body ： A Case Report

Angioleiomyomaisabenignsmoothmuscletumororiginatingfrombloodvessels.Itcanoccurinallpartsofthebodyincludingorbit.Tothebestofourknowledge,ithasnotbeenreport鄄edintheciliarybodyintheliterature.Onlyasmallnumberofleiomyomaoftheciliarybodywerepresented[1鄄6].Sowepresenthereinacaseofangioleiomyomaoftheciliarybodydiagnosedbypathohistologicandimmunohistochemicalex鄄aminationinourcenter.MaterialandMethod1.CaseA32鄄year鄄oldmanwasreferredtousonOctober27,1999witha4鄄monthhistoryofgrad鄄ualdecreaseinvisi…     

Orbital leiomyoma: a case report with clinical, radiological and pathological correlation

Orbital leiomyoma is a benign tumour of smooth muscle origin that can be clinically, radiologically and histopathologically difficult to diagnose due to the rarity of leiomyomas in this location. A 74-year-old woman presented with a 2-month history of painless proptosis. Computed tomography and magnetic resonance imaging studies revealed a well-circumscribed intraconal lesion separate from the optic nerve, and not eroding adjacent bone. A right lateral orbitotomy via a lid crease incision was performed to remove the firm lobulated lesion. Postoperatively there was an obvious decrease in proptosis. Microscopically the lesion was a well-circumscribed tumour composed of spindle cells. There were no light microscopic features to suggest malignancy, and immunohistochemistry was used to confirm the diagnosis of leiomyoma. Leiomyoma is a tumour that is rarely found in the orbit most likely due to the paucity of smooth muscle in this location. The differential diagnosis is wide, and the role of radiology, histology and immunohistochemistry in the diagnosis of leiomyoma is discussed. Surgical excision in this case excluded malignancy, provided a definitive diagnosis of a rare entity and resulted in marked clinical improvement.     

Posterior choroidal leiomyoma: new findings from a case and literature review

Posterior choroidal leiomyoma is a sporadic, rare benign tumor that is always confused with anaplastic melanoma. Here we report a case and provide a review. Most of the preoperative findings in our case were suggestive of malignant choroidal melanoma. However, the contrast enhanced ultrasound (CEUS) suggested a benign hemangioma. In summary, the posterior choroidal leiomyomas were yellowish-white in color and most commonly located in the temporal quadrant of the fundus (11/15). They were more frequent in Asians (13/16), the prevalence was almost equal in males and females (9:7), with a mean age of 35y. Microscopically, the tumor typically showed spindle cell bundles and nonmitotic ovoid nuclei arranged in intersecting fascicles. Vitrectomy is now a popular treatment option and definitive diagnosis can be made after immunohistochemistry. Finally, some summarized features of this tumor differ from those previously described. These may help in the diagnosis of posterior choroidal leiomyoma and differentiation from malignant melanoma.     

Orbital leiomyoma: report of a case and review of the literature

A 10-year-old female presented with slowly progressive proptosis of 1 year's duration. Orbital MRI revealed an extraconal oval mass occupying the lateral half of the mid and posterior orbit. The tumor was isointense to the extraocular muscle and cerebral gray matter on T1-weighted images and hyperintense on T2-weighted images. The patient underwent superolateral orbitotomy, and it was felt that the tumor was totally excised in a piecemeal fashion. Histopathologic examination showed that the tumor was composed of spindle cells arranged in a fibrous stroma rich in dilated sinusoidal capillaries. The nuclei of tumor cells were oval with blunted ends. There were no mitotic figures. Immunohistochemically, the tumor stained positive with smooth muscle actin, desmin, and vimentin. Based on the histopathologic and immunohistochemical staining results, a diagnosis of orbital leiomyoma was made. At 34 months follow-up, the patient continues to have 20/20 vision and is free of tumor recurrence clinically. Orbital leiomyoma is an uncommon tumor. Search of the English literature showed only 15 previous cases of orbital leiomyoma that have been published since 1963.     

砷剂在眼部的新用途

砷剂已经广泛应用于血液系统疾病和实体瘤的治疗。然而，近年来发现，砷剂在眼部疾病作用机制方面的研究也日渐增多，但尚未被研究透彻，且未应用于临床阶段。现就砷剂对相关眼部疾病的作用机制及新用途做一综述。     

Epstein-Barr positive T-cell lymphoma in the ocular region

PURPOSE: To present two cases of rapidly growing tumors in the ocular adnexa. Both tumors were Epstein-Barr virus (EBV) positive peripheral T-cell lymphoma. METHODS: Case 1 was a 60-year-old man with a non-tender ulcerating tumor involving the lateral third of both upper and lower right eyelid. Case 2 was a 55-year-old man with a swelling of the left eyelid expanding cranially and dislocating the left eye, resulting in proptosis and diplopia. Both patients underwent incisional biopsy that did not disclose the malignant nature of the tumors. Clinical evaluation resulted in suspicion of malignancy and surgical excision was performed. RESULTS: The tumors were found to be consistent with EBV-positive peripheral T-cell lymphoma. CONCLUSIONS: Peripheral T-cell lymphoma is uncommon but a diagnosis to be considered in a patient with a tumorous lesion in the eye region. Furthermore, peripheral T-cell lymphoma may be EBV-positive.