急性脑卒中偏瘫病人早期康复护理探讨

目的探讨脑卒中偏瘫病人接受早期康复训练后肢体运动功能的恢复效果。方法选择2005年1月～2006年11月62例卒中偏瘫患者，随机分为观察组和对照组，每组31例。对照组给予药物治疗及未经指导的自我锻炼，观察组在药物治疗的同时进行正规的康复训练。结果早期康复训练在促进患肢功能恢复及提高日常生活能力方面，显著优于单纯药物治疗及恢复期再行功能锻炼。结论急性期康复护理着重在保护良好的功能位和进行肢体运动；恢复期的康复护理着重于坐卧练习、站立与行走练习，而心理护理则贯穿始终。     

锻炼健侧肢体对脑卒中患者的治疗作用

目的：探讨锻炼健侧肢体对脑卒中患者偏瘫肢体的治疗效果。方法：分为治疗组、对照组进行对比研究,两组患者急性期均接受神经内科的常规药物治疗及患肢的康复治疗,治疗组除常规药物治疗及患肢的康复治疗外,同时锻炼健侧肢体并与对照组作对比。结果：治疗组疗效优于对照组（P〈0．01）结论：锻炼健侧肢体对脑卒中患者具有良好治疗效果。     

急性脑卒中偏瘫病人早期康复护理探讨

目的 探讨脑卒中偏瘫病人接受早期康复训练后肢体运动功能的恢复效果.方法 选择2005年1月-2006年11月62例卒中偏瘫患者,随机分为观察组和对照组,每组31例.对照组给予药物治疗及未经指导的自我锻炼,观察组在药物治疗的同时进行正规的康复训练.结果 早期康复训练在促进患肢功能恢复及提高日常生活能力方面,显著优于单纯药物治疗及恢复期再行功能锻炼.结论 急性期康复护理着重在保护良好的功能位和进行肢体运动;恢复期的康复护理着重于坐卧练习、站立与行走练习,而心理护理则贯穿始终.     

早期康复方案用于脑卒中偏瘫患者的价值及日常生活能力(ADL)评估分析

目的探讨早期康复方案用于脑卒中偏瘫患者的价值及日常生活能力。方法收集我院90例2017年9月至2018年1月脑卒中偏瘫患者。按照治疗分组,对照组予以常规内科方法治疗,观察组则予以常规内科方法联合早期康复方案治疗。比较两组临床疗效;在医院接受康复锻炼时间;治疗前后患者运动、日常生活能力;残疾概率。结果观察组临床疗效高于对照组,P0.05;观察组在医院接受康复锻炼时间优于对照组,P0.05;治疗前两组运动、日常生活能力并无明显差异,P 0.05;治疗后观察组运动、日常生活能力优于对照组,P 0.05。观察组残疾概率低于对照组,P0.05。结论常规内科方法联合早期康复方案治疗脑卒中偏瘫的临床疗效确切,可更好改善运动、日常生活能力,值得推广应用。     

超早期良肢位摆放防治偏瘫患者关节挛缩的康复护理

目的:探讨脑卒中偏瘫患者超早期良肢位摆放对患者关节挛缩的影响。方法:将我院收治的104例脑卒中患者随机分为观察组和对照组,每组52例,两组患者均接受神经内科常规治疗和康复训练,对照组患者给予神经内科常规护理;观察组患者在此基础上,入院即进行早期康复护理,给予患肢良肢位摆放。治疗2个月后采用Brunnstrom运动功能分级和Barthel指数评估患者的运动功能,采用Ash-wovoh量表评定防治关节挛缩有效性。结果:治疗后观察组患者Brunnstrom运动功能分级和Barthel指数明显优于对照组(P<0.05);治疗后观察组患者发生关节挛缩12例(23.1%),对照组患者发生关节挛缩35例(67.3%),两组患者关节挛缩发生率比较差异具有统计学意义(P<0.05)。结论:超早期良肢位摆放对于偏瘫患者防止关节挛缩和肢体功能的恢复有积极效果。     

良肢位护理对于急性期脑卒中患者的影响

目的研究分析在脑卒中偏瘫患者中开展良肢体位包房早期康复护理措施的影响。方法选取在本院接受治疗的脑卒中偏瘫患者,选取时间段为2017年1月至2017年10月,病例数为50例。通过随机数字法分组,平均分成对照组和观察组各25例。对照组患者接受常规护理,观察组采取早期康复护理,实施良肢体位摆放。分析两组患者肢体功能恢复效果。结果治疗后两组患者的分数显著高于治疗前,同时治疗后观察组分数显著高于对照组(P0.05)。结论对脑卒中偏瘫患者使用良肢位摆放早期康复护理,可以使患者患侧肌肉痉挛得到有效防治,还可以最大程度保护患者的关节功能,促进肢体功能恢复。     

早期的康复护理对脑卒中偏瘫患者的影响

目的:探讨早期康复护理对急性脑卒中后肢体运动障碍患者的治疗效果。方法:将脑卒中偏瘫患者50例随机分成康复护理组和对照组。对照组只接受常规的药物进行治疗,康复护理组在常规的神经药物治疗的基础上还采用早期的护理康复的干预措施。之后对治疗结果进行评定比较。结果:经过2个月的治疗后患肢的上下功能比较差异有统计学意义(P<0.05)。结论:对急性脑溢血后的肢体运动障碍的患者进行早期的康复护理并结合相应的药物治疗对其肢体功能康复具有非常积极的意义。     

急性脑卒中偏瘫患者早期康复治疗效果的研究

目的 探讨偏瘫早期康复治疗对急性脑卒中患者患肢功能恢复程度和日常生活活动能力(ADL)的影响.方法 选择急性脑卒中偏瘫患者96例,随机分为两组(对照组47例,康复组49例).康复组除了药物治疗外还进行规范化的康复训练,对照组在药物治疗的同时进行未经指导的自我锻炼.结果 经康复治疗后康复组简式Fugl-Meyer评定量(FMA)值、Barthel指数积分均明显高于对照组,差异有显著性意义(P＜0.01).结论 早期实施规范化康复训练能明显改善急性脑卒中患者偏瘫肢体功能和ADL能力,降低致残率,提高生存质量.     

脑卒中偏瘫早期康复护理干预效果分析

目的:探讨脑卒中偏瘫病人接受早期康复护理干预前后和护理干预效果。方法:采用随机分组,将2013年1月-2014年6月于我院就诊的82例脑卒中偏瘫病人,分为观察组和对照组(各41例),对观察组患者在常规护理的基础上,给予护理干预;对照组患者给与常规护理,对两组患者的护理效果分析,比较两组治疗效果。结果:经过早期康复护理干预后,观察组患者治疗总有效率和痊愈率要明显高于对照组患者,组间治疗效果差别具有明显差异P0.05。结论:早期康复护理干预有利于脑卒中偏瘫患者提高患肢运动功能,降低致残率,提高生活质量。     

早期良肢位摆放对脑卒中偏瘫患者肢体功能康复的影响分析

目的 分析早期良肢位摆放对脑卒中偏瘫患者肢体功能康复的影响。 方法 选取 2018 年 6 月至 2019 年 6 月我院收治的脑卒中偏瘫患者 72 例作为研究对象,分为观察组和对照组,观察组在常规护理基础上给予良肢位摆放,对照组仅接受常规护理,比较患者的肢体功能康复情况。 结果 观察组患者肢体功能评分优于对照组,生活能力评分高于对照组,差异具有统计学意义( P<0.05 )。 结论 早期良肢位摆放对脑卒中偏瘫患者的肢体功 能康复具有良好的影响,可以帮助提升其肢体功能评分,促进患者生活能力的恢复,值得推广使用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.