共查询到20条相似文献,搜索用时 635 毫秒
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Altered levels of miR‐21, miR‐125b‐2*, miR‐138, miR‐155, miR‐184, and miR‐205 in oral squamous cell carcinoma and association with clinicopathological characteristics
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Mayakannan Manikandan Arunagiri K. Deva Magendhra Rao Kottayasamy Seenivasagam Rajkumar Ramamurthy Rajaraman Arasambattu K. Munirajan 《Journal of oral pathology & medicine》2015,44(10):792-800
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Pratanporn Arirachakaran Sureeat Luangworakhun Georgios Charalampakis Gunnar Dahln 《Journal of investigative and clinical dentistry》2019,10(2)
In the present study, we identified and evaluated the antibiotic susceptibility of 96 independent, aerobic, Gram‐negative bacillus isolates from 255 Thai HIV‐positive adults who were on Highly‐active anti‐retrovirus therapy (HAART) medication. Another 46 isolates from HIV non‐HAART individuals, vertically transmitted HIV‐positive individuals, and non‐HIV controls were included for comparison. A total of 103 strains were tested for antibiotic susceptibility using disc diffusion for screening and E‐test for minimal inhibitory concentration determination, with special attention on extended‐spectrum beta‐lactamase (ESBL) isolates. Pseudomonas aeruginosa, Pseudomonas luteola, Burkholderia cepacia, Aeromonas hydrophila, Klebsiella, and Enterobacter species were the most common bacteria. All strains were resistant against penicillin, amoxicillin, clindamycin, and metronidazole. No ESBL isolates were found. 相似文献
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Wael M. Al‐Omari BDS MDentSci PhD Rola Shadid BDS MSc Layla Abu‐Naba’a BDS PhD MFDRCS 《Journal of prosthodontics》2010,19(4):263-273
Purpose: The purpose of this in vitro study was to compare the porcelain fracture resistance between screw‐retained, cement‐retained, and combined screw‐ and cement‐retained metal–ceramic (MC) implant‐supported posterior single crowns; and to investigate the effect of offsetting the occlusal screw‐access opening on porcelain fracture resistance of screw‐retained and cement‐retained MC implant‐supported posterior single crowns. Materials and Methods: Forty standardized MC molar‐shaped restorations were fabricated. The 40 restorations were divided into four groups (SRC, SRO, CRP, and CSC) of 10 specimens each. Group SRC: screw‐retained, screw‐access hole placed in the center of the occlusal surface; Group SRO: screw‐retained, screw access hole placed 1 mm offset from the center of the occlusal surface toward the buccal cusp; Group CRP: cement‐retained, zinc phosphate cement was used; Group CSC: cement‐retained with a screw‐access hole in the center of the occlusal surface. The screw‐retained restorations and abutments were directly attached to 3i implant fixtures embedded in acrylic resin blocks. Subsequently, all test specimens were thermocycled and vertically loaded in a universal testing machine at a crosshead speed of 2 mm/min until fracture. Mean values of load at fracture (in N) were calculated in each group and compared with a one‐way ANOVA and Tukey's Studentized test (α= 0.05). Results: Mean values of loads required to fracture the restorations were as follows (N): Group SRC: 1721 ± 593; Group SRO: 1885 ± 491; Group CRP: 3707 ± 1086; Group CSC: 1700 ± 526. Groups SRC, SRO, and CSC required a significantly lower force to fracture the porcelain than did the CRP group (p < 0.05). Conclusion: The cement‐retained restorations showed significantly higher mean fracture loads than the restorations having screw‐access openings in their occlusal surface. The position of the screw‐access hole within the occlusal surface did not significantly affect the porcelain fracture resistance. 相似文献
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Ana P. C. Q. Herkrath Mario V. Vettore Adriana C. de Queiroz Paula L. N. Alves Sarah D. C. Leite Juliana V. Pereira Maria A. B. Rebelo Fernando J. Herkrath 《European journal of oral sciences》2019,127(3):254-260
The aim of this study was to investigate the association between orthodontic treatment need and oral health‐related quality of life (OHRQoL) among 12‐yr‐old children. The study also assessed whether self‐esteem modifies and/or moderates this relationship. Cross‐sectional data on 406 schoolchildren aged 12 yr were analyzed. Data on socio‐economic and demographic characteristics, dental pain, self‐esteem, and OHRQoL were collected using validated questionnaires. Orthodontic treatment need was assessed, through dental examinations, using the dental aesthetic index (DAI). Multiple negative binomial regression and path analysis were used to estimate the association of orthodontic treatment need and self‐esteem with OHRQoL. A modifying effect of self‐esteem on the relationship between DAI and OHRQoL was observed. Self‐esteem did not mediate the abovementioned relationship. Children with lower scores of self‐esteem had worse OHRQoL among those with lower orthodontic treatment need (a DAI score of < 31). However, self‐esteem did not influence the association between DAI and OHRQoL in children with greater orthodontic treatment need (a DAI score of ≥ 31). Self‐esteem attenuated the impact of malocclusion on OHRQoL in children with minor or definite malocclusion, but not among those with severe or very severe malocclusion. Self‐esteem appears to buffer the impact of malocclusion on OHRQoL in children with minor orthodontic treatment need. 相似文献
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Concentration‐dependent effect of bleaching agents on the immunolabelling of interleukin‐6, interleukin‐17 and CD5‐positive cells in the dental pulp
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F. Benetti J. E. Gomes‐Filho L. L. Ferreira G. Sivieri‐Araújo E. Ervolino A. L. F. Briso L. T. A. Cintra 《International endodontic journal》2018,51(7):789-799
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Gingival crevicular fluid levels of MMP‐8, MMP‐9, TIMP‐2, and MPO decrease after periodontal therapy
Andrea M. Marcaccini Cesar A. Meschiari Leonardo R. Zuardi Tiago Sampaio De Sousa Mario Taba Jr. Juliana M. Teofilo Anna L.B. Jacob‐Ferreira Jose E. Tanus‐Santos Arthur B. Novaes Jr. Raquel F. Gerlach 《Journal of clinical periodontology》2010,37(2):180-190
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Background/aims: Bacterial pathogens involved in periodontal diseases exert their destructive effects primarily by stimulating the host cells to increase their secretion of proinflammatory cytokines and matrix metalloproteinases (MMPs). This study aimed to determine the epithelial cell matrix metalloproteinase and interleukin‐8 (IL‐8) secretion upon exposure to fusobacteria. Methods: Eight different oral and non‐oral Fusobacterium strains were incubated with HaCaT epithelial cells. Gelatin zymography and Western blot analysis were performed to detect collagenase 3 (MMP‐13), gelatinase A (MMP‐2), gelatinase B (MMP‐9), and IL‐8 secretion by epithelial cells. Results: All Fusobacterium strains, especially Fusobacterium necrophorum ATCC 25286, Fusobacterium nucleatum ATCC 25586, and Fusobacterium varium ATCC 51644, increased MMP‐9 and MMP‐13 secretion. Fusobacterium simiae ATCC 33568, and to a lesser extent F. nucleatum and F. necrophorum, increased epithelial MMP‐2 secretion. F. nucleatum and F. necrophorum also increased IL‐8 secretion. F. varium ATCC 27725, a strain that only weakly stimulated MMP production, strongly increased the IL‐8 production, suggesting that their expression is differently regulated. Conclusion: We conclude that the pathogenic potential of fusobacteria may partly result from their ability to stimulate secretion of MMP‐9, MMP‐13, and IL‐8 from epithelial cells. 相似文献