胸主动脉瘤合并冠心病同期外科治疗(附15例报告)

目的 总结胸主动脉手术同期行冠状动脉旁路移植术的经验。方法1999年6月至2002年7月，胸主动脉瘤手术同期行冠状动脉旁路移植术15例，均为男性；年龄40～66岁，平均57．2岁；体重60～89kg，平均70．2kg。病种包括主动脉根部瘤5例、升主动脉瘤2例、弓部瘤3例、主动脉夹层5例。经胸骨正中切口在全麻低温体外循环下手术14例；左外侧切口非体外循环下冠状动脉旁路移植同期股股转流降主动脉置换术1例。结果术后早期30d内死亡1例，随访1～36个月，无远期死亡，无再次手术及冠心病相关事件发生。结论胸主动脉置换术与冠状动脉旁路移植术能够安全同期进行，同期冠心病的再血管化对预防冠心病相关事件的发生有积极作用。     

主动脉手术并同期冠状动脉旁路移植术的临床总结

目的总结行主动脉手术同期行冠状动脉旁路移植术的临床经验。方法回顾分析1997年11月至2004年8月,36例同期行主动脉手术和冠状动脉旁路移植术患者的临床资料。36例中,主动脉夹层19例,主动脉瘤17例。年龄(57±12)岁。其中急性A型主动脉夹层10例,术中探查见冠状动脉开口受累7例,冠状动脉为索条状2例,1例在外院行冠状动脉造影检查发现;慢性A型主动脉夹层7例,术中发现冠状动脉开口受累2例,冠状动脉呈索条状3例,术前造影检查发现冠状动脉病变2例;B型主动脉夹层2例;真性主动脉瘤均为术前冠状动脉造影检查发现冠状动脉病变。移植血管共57支,其中动脉6支,静脉51支。结果平均体外循环时间(157±54)m in,心肌阻断时间(98±31)m in。围手术期死亡5例(均为A型主动脉夹层),分别为低心排血量综合征、心源性休克并发多脏器功能衰竭3例,脑疝1例,内脏缺血坏死1例。术后发生并发症2例,发生率为6%,分别为二次开胸止血和呼吸功能衰竭气管切开。结论主动脉夹层累及冠状动脉和冠状动脉本身的病变严重影响预后。对年龄>50岁的主动脉瘤患者,于术前常规行冠状动脉造影检查,行单纯主动脉瘤手术并同期行冠状动脉旁路移植手术安全、可靠。     

胸主动脉瘤外科综合治疗

目的 总结2001年5月～2005年5月我院对223例各类胸主动脉瘤行介入腔内隔绝、“杂交手术”等综合外科治疗的经验,探讨手术方法的选择和手术新技术的应用。方法 单纯Bentall手术83例,单纯升主动脉置换17例,David手术3例,Wheat手术7例,Bentall及右半弓人工血管置换术12例,全弓人工血管置换联合象鼻或改良象鼻手术10例,“杂交手术”（Bentall手术＋全弓置换＋介入腔内隔绝）8例,降主动脉人工血管置换术4例,降主动脉及左半弓人工血管置换术3例,腔内覆膜支架介入治疗降主动脉夹层动脉瘤76例。急诊手术98例,同期行冠状动脉旁路移植术6例（包括“杂交手术”＋冠状动脉旁路移植术1例）。结果 手术死亡9例：1例Ⅰ型夹层动脉瘤术后死于大面积脑出血;2例Bentall手术后呼吸功能衰竭合并肺部感染,分别在术后7、12 d死亡;1例急性肝功能衰竭,经人工肝,血浆置换治疗未好转术后3 d死亡;2例分别于术后8、14 d死于多脏器功能衰竭;2例分别于术后4、6 d死于心脏功能衰竭;1例术后3 d脑梗塞家属放弃治疗。76例腔内隔绝术即时操作成功率100%,即夹层裂口完全封闭,恢复真腔血流,动脉假腔不再显影。214例随访4～52个月,（27±18）个月,3个月内无死亡。1例Bentall术后8个月因突发心律紊乱死亡;1例Bentall及右半弓人工血管置换术后12个月因脑栓塞死亡;1例马凡综合征行Bentall术后6个月出现降主动脉夹层动脉瘤,再次行胸降主动脉置换和肋间血管移植痊愈。结论 早期根据病变部位、程度采用包括经导管植入支架、杂交手术等综合外科治疗可以简化手术操作、提高手术安全性、降低胸主动脉瘤手术病死率。深低温停循环联合右锁骨下动脉插管选择性脑灌注是一种简便易行有效的脑保护方法。     

正中切口解剖外旁路移植术一期治疗主动脉缩窄合并心脏畸形

目的总结正中切口解剖外旁路移植术一期治疗主动脉缩窄合并心脏畸形的外科治疗经验,以提高手术疗效。方法1997年7月至2008年7月,采用正中切口解剖外旁路移植术一期治疗主动脉缩窄合并心脏畸形31例,其中男20例,女11例;年龄31．9±11．7岁。合并的心脏畸形包括：主动脉瓣狭窄或关闭不全22例,二尖瓣狭窄或关闭不全9例,动脉导管未闭5例,升主动脉瘤4例,室间隔缺损3例,冠心病2例。解剖外旁路移植术包括升主动脉-腹主动脉旁路移植术22例,升主动脉-心包后降主动脉旁路移植术9例。同期手术包括主动脉瓣置换术16例,主动脉根部置换术6例,二尖瓣成形或置换术9例,升主动脉置换或成形术4例,动脉导管未闭缝合术5例,室间隔缺损修补术3例,冠状动脉旁路移植术2例。结果住院死亡1例（3．2％）,术后39d死于感染性中毒性休克。术后上、下肢收缩压压差较术前明显下降（13．7±10．2mmHg vs．64．2±25．3mmHg,P〈0．05）。随访27例,随访时间4～73个月,无晚期死亡、与人工血管相关的并发症和再次手术患者。结论正中切口解剖外旁路移植术是一期治疗成人及青少年主动脉缩窄合并心脏畸形的一种安全有效的手术方法。升主动脉腹主动脉旁路移植术及升主动脉-心包后降主动脉旁路移植术均可获得满意疗效。     

胸主动脉夹层的外科治疗

目的总结胸主动脉夹层(AD)的外科治疗经验。方法1993年至2003年4月手术治疗A型AD40例，B型20例，其中急性夹层16例。A型采用中度低温体外循环13例，深低温停循环(DHCA)和上腔静脉逆灌(RCP)27例；行升主动脉置换24例，升主动脉和半弓置换11例，升主动脉、全弓和象鼻手术5例；同期行Bentall手术18例，主动脉瓣置换8例，冠状动脉旁路移植术1例。B型采用左心转流7例，股一股转流2例，DHCA 11例；行近端降主动脉置换14例，全胸降主动脉置换或伴肋间动脉移植6例。结果全组术后死亡率10％(急性夹层18．8％，慢性夹层6．8％)，近3年降至4．4％。术后并发呼吸功能不全8例，二次开胸止血3例，延迟性心包压塞和腹腔内出血各2例，声音嘶哑3例。结论正确掌握手术指征、手术技巧和术中脑保护是手术治疗AD的关键。A型夹层的手术范围应依据内膜破裂口位置决定。     

≥65岁老年人心脏瓣膜病的外科治疗

目的总结老年人瓣膜病的手术效果。方法 1993年至2004年252例≥65岁老年瓣膜病病人接受瓣膜手术,占同期瓣膜手术5．5％(252／4546例),其中男147例,女105例;平均年龄(67．9± 2．9)岁。风湿性瓣膜病201例(79.8％),非风湿性瓣膜病51例(20．2％)。术前心功能Ⅲ-Ⅳ级141例 (56．0％)。主动脉瓣置换63例,二尖瓣置换93例,二尖瓣成形42例,主动脉瓣置换+二尖瓣置换或成形47例,三尖瓣置换或成形7例。同期行冠状动脉旁路移植术34例。结果手术死亡23例(9．1％), 逐年病死率有下降趋势。与同期瓣膜手术16-64岁组相比,术后ICU时间显著延长[(60．1±101．2)h对 (43．0±70．6)h,P=0．00],术后带气管插管时间明显延长[(30．6±42.8)h对(24．1±45．0)h,P=0．02], 术后并发症发生率明显高(10．6％对6．4％,P=0．01),住院时间明显延长[(25．7±41．3)d和(19．6± 14．4)d,P=0．00]。手术死亡病人术前心功能级别明显高于生存者[(2．8±1．0)级对(2.4±1．0)级,P< 0．05];术前射血分数差异无统计学意义(55．8％对59．5％)。结论老年人瓣膜病手术总体手术病死率可以接受,近2年手术病死率已接近5％。多元回归分析显示,并行冠状动脉旁路移植术、主动脉瓣和二尖瓣双瓣手术、术后急性肾衰需要透析、体外循环时间长、主动脉阻断时间长是住院病死率的独立预测因子。     

主动脉手术同期冠状动脉旁路移植术97例

目的 总结行主动脉手术同期行冠状动脉旁路移植术的临床经验.方法 回顾分析2009年1月至2011年12月,97例同期行主动脉手术和冠状动脉旁路移植术患者的临床资料.男88例,女9例;年龄(57.6±9.5)岁.其中,真性动脉瘤63例,主动脉夹层25例,主动脉狭窄及闭塞性病变7例,主动脉溃疡2例.诊断冠状动脉病变依靠术前冠状动脉造影、术前冠状动脉计算机体层摄影血管成像(CTA)检查和术中探查3种方式.术前确诊冠状动脉病变的比例分别为,真性动脉瘤组93.7％(59/63例),主动脉夹层组40.0％(10/25例),主动脉溃疡和狭窄闭塞组均为100.0％.结果 术前未明确冠状动脉病变者行主动脉手术同期合并抢救性冠状动脉旁路移植术,术前明明确冠状动脉病变的患者同期行常规冠状动脉移植术.两种情况各死亡3例.Fisher精确检验P=0.078,差异有统计学意义.结论 对主动脉病变患者,术前尽可能常规行冠状动脉造影检查或冠状动脉CTA检查,主动脉手术同期合并常规冠状动脉旁路移植手术安全、可靠.     

冠状动脉旁路移植术同期瓣膜手术的经验

目的 探讨同期施行冠状动脉旁路移植术和瓣膜手术的方法,疗效及影响因素。方法 回顾分析１９９５～１９９８年间１５例冠状动脉旁路移植术时,同期行二尖瓣置换或成形、主动脉瓣置换、联合瓣膜置换、Ｂｅｎｔａｌｌ术。结果 瓣膜病病因中,风湿性８例,退行性４例,缺血性３例,手术病死率为６．７％（１／１５）‘４例发生低心输出量综合征,其中３例需行主动脉内球反博;５例二尖瓣成形术后,反流面积从６．５～１５．０ｃｍ＾     

升主动脉-腹主动脉旁路移植术治疗Ⅱ、Ⅲ型大动脉炎

目的：为了有效治疗累及胸腹主动脉的Ⅱ、Ⅲ型大动脉炎，探讨升主动脉－腹主动脉旁路移植术的手术疗效。方法：自1976年至2001年采用升主动脉－腹主动脉旁路移植术治疗Ⅱ、Ⅲ型大动脉炎47例，同期行人工血管与肾动脉旁路移植术10例，冠状动脉旁路移植术和自体肾移植术各2例，三尖瓣成形术和髂动脉旁路移植术各1例。结果：术后1例死于凝血障碍出血，死亡率为2．13％；术后因肠梗阻再1列；存活患者血压和血运均明显改善，上肢血压较术前明显下降，平均为118／77mmHg(1kPa=7.5mmHg)vs 177/83mmHg；术后上、下肢血压差别无显著性意义。平均随访8．2年，远期死亡2例（4．35％），再手术1例，远期效果优良率为81．82％。结论：升主动脉－腹主动脉旁路移植术是治疗Ⅱ、Ⅲ型大动脉炎的简单、安全、远期疗效好的方法。     

冠状动脉支架植入术后Stanford A型主动脉夹层的外科治疗

目的 分析冠状动脉支架植入术后Stanford A型主动脉夹层患者的外科治疗方式,探讨其手术技术及手术时机。方法 回顾性分析2016年4月—2019年7月首都医科大学附属北京安贞医院连续收治的1 246例Stanford A型主动脉夹层患者的临床资料。纳入冠状动脉支架植入术后Stanford A型主动脉夹层患者。结果 最终纳入患者19例,其中男16例、女3例,年龄35～66(54±7)岁。19例患者中急性主动脉夹层11例。AC型（DeBakeyⅠ型）主动脉夹层15例,AS型（DeBakeyⅡ型）4例。AC型患者中行孙氏手术（全弓置换+支架象鼻手术）10例,部分弓置换5例;19例患者中同期行冠状动脉旁路移植术7例,二尖瓣置换术1例;4例患者术中取出位于右冠开口的支架。本组住院死亡1例,主因术前合并脏器灌注不良,术后死于多脏器功能衰竭。18例患者经治疗后痊愈出院,平均随访30(18～56)个月,其中1例因冠状动脉吻合口漏行二次漏修补术,1例因远端夹层新发破口行胸主动脉腔内修复,1例因左主干支架闭塞急诊行经皮冠状动脉介入治疗,1例因髂动脉闭塞行股股转流。结论 冠状动脉支架植入术后Stanfo...     

One-stage thoracic aortic aneurysm treatment and coronary artery bypass grafting

OBJECTIVE: The treatment of thoracic aortic aneurysm accompanied by ischemic heart disease presents a surgical challenge and has up to now shown a high hospital mortality rate. This report discusses the factors contributing to improved results in these cases. METHODS: We conducted a retrospective analysis of the records of 24 consecutive patients who had undergone replacement of thoracic aorta with combined coronary artery bypass grafting (CABG) between May 1991 and October 1998. Fifteen patients received total arch replacement (Arch-with-CABG Group), and the other 9 patients received the Bentall operation (Bentall-with-CABG Group). These results were compared with those patients who had undergone replacement of the thoracic aorta without CABG (Without-CABG Group). RESULTS: In the combined CABG groups, the overall operative mortality rate was 16.7%. In comparison with the Arch-without-CABG Group, there was a significantly longer cardiopulmonary bypass time and longer selective cerebral perfusion time in the Arch-with-CABG Group. However, no significant difference was observed in postoperative complications between the two groups. In addition, there was no significant difference in either actuarial survival or the cardiac-event-free rate at 5 years between the replacement of thoracic aorta with- and without-CABG Groups (83.1% vs. 90.4%, and 78.5% vs. 77.7%, respectively). No reoperation and no late death were observed during the follow-up period (mean 21.3 months). CONCLUSIONS: We concluded that replacement of the thoracic aorta combined with CABG can be carried out safely, and that revascularization for coronary artery disease is useful for preventing any occurrence of cardiac event.     

Simultaneous multi-vessel coronary artery bypass grafting, ischemic mitral regurgitation repair and descending aortic aneurysm replacement: analysis of technical points

The combination of coronary artery disease and its complications (ischemic mitral regurgitation etc.) with the aneurysm of the descending thoracic aorta is not a rare case. The single-stage correction of coronary/intracardiac/aortic lesions may be considered as a way of managing the combined patients. Simultaneous multi-vessel coronary artery bypass grafting, suture mitral annuloplasty and descending aortic aneurysm replacement with synthetic prosthesis is described. The operation was performed through the left thoracotomy with cardiopulmonary bypass established by the cannulation of the ascending aorta and of the right atrial appendage. Ventricular fibrillation and no clamping of the ascending aorta were used. The circulatory arrest was induced for the construction of the proximal anastomosis between the descending aorta and the synthetic prosthesis. No complications related to the operation were diagnosed for the 14-month follow-up. Several technical points seem optimal for the combined procedure: (1) Minimization of manipulations on the ascending aorta (using of pedicled left internal thoracic artery; construction of the proximal anastomoses with synthetic aortic prosthesis; unclamped ascending aorta). (2) Revascularization of all coronary areas and correction of intracardiac lesions through the left thoracotomy. Individual planning of the procedural technical points for every patient may provide a safe feasibility of the combined procedure.     

Surgical treatment of aortic arch aneurysm combined with coronary artery stenosis.

OBJECTIVE: We present operative results of aortic arch aneurysm associated with coronary artery stenosis, and evaluate the operative risk of graft replacement of the aortic arch and concomitant coronary artery bypass grafting (CABG). PATIENTS AND METHODS: From January 1991 to December 2001, we treated 16 patients with aortic arch aneurysm and coronary artery stenosis. The patients, 3 women and 13 men (study group) ranged from 58 to 79 years of age, average 68.1 5.3 years. With the aid of deep hypothermic cardiopulmonary bypass, we performed graft replacement of the aortic arch aneurysm and concomitant CABG. We bypassed 31 coronary arteries. The bypass grafts included saphenous vein (n=16), left internal thoracic artery (n=4), right internal thoracic artery (n=1), right gastroepiploic artery (n=5) and inferior epigastric artery (n=2). The number of bypassed coronary arteries per patient ranged from 1 to 3, average 2.1 0.8/patient. A comparative study was performed between the study group and a control group of patients (n=39) who had undergone only graft replacement of the aortic arch. RESULTS: There was no significant difference between the two groups regarding: operation time, cardiopulmonary bypass time, cardiac arrest time, intraoperative bleeding volume, and early mortality rate. However, in the patients (n=4) of the study group who had undergone total arch graft replacement with three vessel CABG, the cardiopulmonary bypass time was significantly longer than that of the patients in the control group who underwent total arch graft replacement (n=19, P<0.05). Two of the 16 study group patients died in the early postoperative period, resulting in 12.5% early mortality rate. In the control group, four of 39 patients (10.3%) died in the early postoperative period. CONCLUSIONS: CABG combined with graft replacement of the aortic arch does not increase operative risk when the number of bypassed vessels is within two vessels, but may increase risk when three or more vessels are bypassed.     

Patency of saphenous vein coronary artery bypass grafts from the vascular prosthesis of the ascending aorta.

BACKGROUND: Patients who have Stanford type A aortic dissection with impaired coronary arteries or who have aneurysms from the ascending aorta to the aortic arch with coronary artery disease need coronary artery bypass grafting (CABG) with tube graft replacement of the ascending aorta simultaneously. When vein grafts are used for CABG in these patients, the proximal anastomoses of vein grafts are attached to the prosthetic tube graft of the ascending aorta. However, the validity of proximal anastomoses of vein grafts to the prosthetic tube graft of the ascending aorta has not been confirmed. PATIENTS AND METHODS: We retrospectively analyzed patients who underwent venous coronary bypass grafting with prosthetic graft replacement of the ascending aorta. Between January 1984 and October 2002, 35 patients underwent CABG using saphenous vein grafts at the time of tube graft replacement of the ascending aorta, and the proximal anastomoses of the vein grafts were attached to the tube graft of the ascending aorta. Thirty-three venous bypass grafts were analyzed in 24 survivors. RESULTS: The postoperative catheterization showed only one early vein graft occlusion of 16 vein grafts anastomosed distally to the left anterior descending artery (LAD). All 14 venous grafts anastomosed to the right coronary artery (RCA) and 3 to the left circumflex artery (LCX) were patent. Therefore, the postoperative patency rate at discharge was 97.0% (32/33). Spiral computed tomography performed for long term follow-up revealed occlusion of two vein grafts (3.5 years and 9.7 years) anastomosed to the LAD. CONCLUSIONS: The patency rate of vein grafts anastomosed from prosthetic grafts of the ascending aorta to the native coronary arteries was similar to that of conventional CABG using saphenous vein grafts.     

Aortic operation after previous coronary artery bypass grafting

OBJECTIVES: Aortic surgery for progressive aortic valve disease or aortic aneurysm after previous coronary artery bypass grafting (CABG) is a challenging procedure. We report the outcome of aortic reoperation after previous CABG and evaluate our management of patent grafts and our methods for obtaining myocardial protection. METHODS: From February 2001 to July 2003, 6 patients with progressive aortic valve disease and aneurysm of the thoracic aorta were operated on. The group comprised 3 men and 3 women with a mean age of 67.6 years. There were 4 patients with an aneurysm of the aortic arch, 1 with chronic ascending aortic dissection, and 1 with progressive aortic valve stenosis. The interval between previous CABG and aortic surgery was 74.0 +/- 44.2 months. All reoperations were performed via median resternotomy. Myocardial protection was obtained by hypothermic perfusion of patent in-situ arterial grafts following cold-blood cardioplegia administration via the aortic root under aortic cross clamping. RESULTS: The operative procedure was aortic arch replacement in 4 patients, ascending aortic replacement with double CABG in 1, and aortic valve replacement in 1. All patients survived the reoperation. Postoperative maximum creatine kinase-MB was 49.2 +/- 29.8 and no new Q-waves occurred in the electrocardiogram nor were any new wall motion abnormalities recognized on echocardiography. There were no late deaths during a follow-up of 30.7 months. CONCLUSION: Reoperative aortic procedures after CABG can be performed safely with myocardial protection via hypothermic perfusion of a patent in-situ arterial graft.     

Aortic stent-grafting: successful introduction into the combined procedure for coronary artery bypass grafting and aortic aneurysm repair.

OBJECTIVES: Coronary artery bypass grafting (CABG) and combined stent-grafting (SG) were evaluated to reduce morbidity and mortality of patients with descending or infrarenal aortic aneurysm. METHODS: CABG and SG (thoracic n=6, infrarenal n=36) were performed during the same hospitalization in 42 patients (mean age of 73+/-14 years). In 29 patients (mean Euroscore: 9), SG was performed under local anesthesia 9+/-3 days after coronary surgery (simultaneous) and in 13 patients (mean Euroscore: 7) during the same anesthesia (synchronous). In the latter group, 11 out of 13 patients underwent off-pump CABG. All aneurysms were treated by implantation of commercially available self-expanding grafts. RESULTS: CABG was successful in all, but one patient with left internal mammary artery hypoperfusion syndrome, requiring an additional distal saphenous graft to the left anterior descending coronary artery. SG was uneventful in 98% (41/42 patients). Postoperative computerized tomography showed incomplete sealing in seven patients (17%), but only the two attachment endoleaks had to be treated by one proximal and one distal SG extension. Overall hospital stay for the synchronous repair was 12.5+/-6 days and that of the simultaneous group 17.5+/-7 days. Thirty-day mortality was 5% (2/42) as one patient of the simultaneous group experienced a lethal cerebral embolism during SG and one patient of the synchronous group developed an untreatable infection. In the follow-up of 4 years, there were two vascular reinterventions but no additional procedure-related morbidity or mortality. CONCLUSIONS: This experience shows that combined CABG and SG of thoracic or infrarenal aortic aneurysm is a safe and less-invasive alternative to the open graft repair, especially in the older patients or patients with severe comorbidities.     

Minimized mortality and neurological complications in surgery for chronic arch aneurysm: axillary artery cannulation, selective cerebral perfusion, and replacement of the ascending and total arch aorta

OBJECTIVE: Cerebral complication is still a major concern in surgery for arteriosclerotic aortic arch disease. For preventing this complication, axillary artery cannulation, selective cerebral perfusion, and replacement of the ascending and arch aorta were applied to thoracic aortic aneurysm involving aortic arch. METHOD: From May 1999 to July 2002, consecutive 39 patients with true aneurysm (29 patients) or chronic aortic dissection (10 patients) involving aortic arch underwent replacement of the ascending and arch aorta with an elephant trunk under hypothermic cardiopulmonary bypass through the axillary artery cannulation and selective cerebral perfusion. The brain was continuously perfused without any intermission through the axillary artery. Concomitant operation included coronary artery bypass grafting (CABG) in two patients, aortic valve replacement (AVR) in one, Bentall operation in two, mitral valve replacement (MVR) in one, and aortic valve sparing operation in one. Patient age at operation was 40-84 (72 + 9) years and 24 of them were older than 70 years of age. RESULTS: There was one operative death (2.5%) due to bleeding from the left lung, and one hospital death due to respiratory failure. Postoperative permanent neurological dysfunction was found in one patient (2.5%). Two patients presented temporary neurological dysfunction (5%). Thirty-six of the 39 patients were discharged from hospital on foot. CONCLUSION: Continuous perfusion through the axillary artery with selective cerebral perfusion and replacement of the ascending and arch aorta may minimize cerebral complication leading to satisfactory results in patients with chronic aortic aneurysm involving aortic arch.     

Surgical treatment of coexistent aortic, peripheral vascular and coronary disease

To determine the priority of the surgical treatment of coexistent aortic and coronary disease (CAD), we reviewed 19 cases of aortic aneurysm combined with severe coronary lesions who underwent operation from Jan, 1984 to Aug, 1989. There were 15 cases of abdominal and 4 cases of thoracic aneurysm. All patients had graft replacement for the aneurysm and 12 patients had elective aortocoronary bypass surgery (CABG), one had percutaneous transluminal coronary angioplasty and 6 received medical treatment for CAD. In 6 cases, CABG preceded abdominal aneurysm operation. In 3 cases of ascending thoracic aneurysm, simultaneous coronary and aortic operation were performed. There were no early and late operative death. In an attempt to reduce perioperative myocardial infarction which is one of the most frequent complications of aneurysmal operation, we performed routine coronary angiogram before operation. In 104 patients considered for elective aortic and peripheral vascular disease, coronary angiogram were performed. The incidence of coexistent coronary artery disease in peripheral vascular and aortic disease were 46.1%. The incidence of multiple vessel CAD in patients with aortic and peripheral disease were high. Our surgical strategy for coexistent aortic, peripheral vascular and coronary disease is basically staged operation and simultaneous operation are performed only in ascending and proximal arch aneurysm.