不同浓度罗哌卡因术后硬膜外镇痛效果的观察

目的探讨不同浓度罗哌卡因复合芬太尼用于术后硬膜外镇痛效果。方法60例剖宫产手术后患者，随机分为0．25％罗哌卡因组（Ⅰ组）、0．179％罗哌卡因组（Ⅱ组）和0．15％罗哌卡因组（Ⅲ组），均复合芬太尼硬膜外自控镇痛，速率2mL／h，观察其视觉模拟（VAS）评分和Bromage评分情况。结果术后6、12、24和48hVAS评分，Ⅲ组显著高于Ⅰ、Ⅱ组；Bromage评分Ⅰ组显著高于Ⅱ、Ⅲ组；均无明显不良反应。结论0．179％罗哌卡因复合芬太尼对剖宫产术后镇痛效果确切，无运动阻滞及并发症，适合临床应用。     

罗哌卡因切口浸润对甲状腺术后镇痛效果的临床观察

目的 观察甲状腺手术患者术毕罗哌卡因切口局部浸润的术后镇痛效果.方法 60例择期甲状腺手术患者,随机分为局部浸润组和对照组各30例,局部浸润组患者于手术结束前用1％罗哌卡因5 mL在手术切口周围做局部浸润麻醉,对照组患者不做局部浸润麻醉处理.记录术后4、8、12、24 h的疼痛视觉模拟评分（VAS）及两组切口渗血程度、切口拆线时间及恶心呕吐等不良反应情况,并于术前、术后4、24 h分别抽取外周静脉血测其血浆皮质醇浓度.结果 术后4、8、12、24 h局部浸润组患者镇痛效果明显优于对照组（P＜0.05）;两组切口渗血程度、切口拆线时间及恶心呕吐等不良反应情况的差异均无统计学意义（P＞0.05）;两组患者术后4h的血浆皮质醇浓度较术前明显增高,且对照组高于局部浸润组（P＜0.05）.结论 甲状腺腺叶切除术患者术毕切口局部浸润罗哌卡因对术后有良好的镇痛效果.     

罗哌卡因用于会阴侧切术的术后镇痛效果

目的 比较罗哌卡因与利多卡因用于会阴侧切术的术后镇痛效果.方法 选择无心、肺疾患和无肝、肾功能不全的足月产妇80例,随机分为两组,每组40例.Ⅰ组用0.375%罗哌卡因15 ml,Ⅱ组用1%利多卡因溶液15 ml,分别在产妇会阴侧切前行阴部神经阻滞麻醉和会阴皮下浸润麻醉.比较两组产妇的镇痛效果、生命体征以及观察新生儿Apgar评分.结果 Ⅰ组术后镇痛时间比Ⅱ组明显延长,12 h内基本无痛,24 h内疼痛减轻,对产妇和新生儿生命体征均无不良影响.结论 罗哌卡因行阴部神经阻滞麻醉及局部浸润麻醉术后镇痛效果优于利多卡因.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

不同浓度罗哌卡因术后臂丛神经镇痛的效果观察

Objective To compare the antalgic effects of ropivacaine in various doses on brachial plexus nerves. Methods 87 patients undergoing upper arm surgery were enrolled in this study. The patients were unpremed-itated. The patients were randomized to receive ropivacaine of 0.30,0.25 or 0.20% (group Ⅰ,Ⅱ and Ⅲ) with mor-phine of 0.1mg/ml and Lidocaine of 10mg/ml. In order to analygesia of brachial plexus nerves,the rejecting of load dose is firstly 10ml,the total dose is 10ml/24h interval every time,the antalgic time is about 50 hours. To compare the antalgic effects of ropivacaine in various doses based on standard of VAS. Based on standard of Bromage to assess the situation of motor neuron blocking. Results According to standard of VAS in 6,12,24 and 48 hours after underwent surgery, the group Ⅲ is more effective than group Ⅰ and group Ⅱ ; according to standard of Bromage, the group Ⅰ is more effective than group Ⅱ and group Ⅲ. it has no adverse reactions to patients. Condusion 0. 25% of ropiva-eaine with morphine of 0.1mg/ml and lidocaine of 10mg/ml have obtained good antalgic effects for patients after un-dergoing upper arm surgery,it is fit for applying in clinic.     

罗哌卡因用于术后硬膜外镇痛的临床观察

目的 比较三种不同浓度罗哌卡因伍用吗啡及格拉司琼用于术后硬膜外镇痛的效果。方法90例择期妇科手术患者，随机分为三组，Ⅰ组为0．25％罗哌卡因组，Ⅱ组为0．20％罗哌卡因组．Ⅲ组为0．125％罗哌卡因组，三组均复合吗啡（6μg／ml）和格拉司琼（0．03mg／ml），硬膜外自控镇痛（PCEA），2ml／h。以VAS评分比较三组术后PCEA的镇痛效果，Bromage评分评定运动阻滞情况。结果术后6、12、24和48hVAS评分，Ⅲ组显著高于Ⅰ、Ⅱ组；Bromage评分Ⅰ组显著高于Ⅱ、Ⅲ组。无麻醉并发症。结论0．20％罗哌卡因复合吗啡和格拉司琼用于妇科手术患者术后镇痛效果确切，无明显运动阻滞作用．适合临床应用。     

罗哌卡因用于分娩镇痛的临床观察与护理

目的：观察罗哌卡因用于分娩镇痛的临床效果,加强罗哌卡因用于分娩镇痛的护理。方法：选择40例拟阴道分娩正常初产妇随机分为两组,观察组在产妇宫口开至3cm时行硬膜外穿刺置管,并开通静脉输液,确定麻醉平面后,以0．16％罗哌卡因维持镇痛,直至分娩结;对照组以自然方式分娩,在围分娩镇痛期密切观察产程、宫缩强度、胎心音、监测产妇的血压、脉搏、呼吸、血氧饱和度（SpO2）,镇痛效果采用VAPS评分法进行疼痛评分,运动神经阻滞以Bromage分级评分,新生儿出生后1－5min进行Apgar评分,分娩后24h新生儿NACS评分。结果：40例围分娩期生命体征平稳,VAPS评分观察组对照组明显降低（P＜0．01）,对运动神经阻滞两组相比无明显差异,对产程的影响,观察线产程对照组,但无明显差异（P＞0．05）。,宫缩强度、胎心音、Apgar评分两组无明显差异器械助产率及剖宫产率,观察组较对照组低,分娩后24h新生儿NACS评分,观察组较对照组增高明显（P＜0．05）。结论：罗哌卡因镇痛完善,对产妇、新生儿无无影响,是一种理想的分娩镇痛药。     

不同浓度罗哌卡因用于妊娠期高血压病产妇术后镇痛效果观察

目的观察不同浓度罗哌卡因对妊娠期高血压病产妇的术后镇痛效果。方法将60例符合妊娠期高血压病诊断标准的初产妇随机分成3组各20例,A、B、C组分别予0.15%、0.20%、0.25%罗哌卡因100mL,行硬膜外自控镇痛,背景速率5mL/h,自控剂量2mL/次,锁定时间30min对产妇作术后镇痛视觉模拟（VAS）评分和Bromage评分,并观察镇痛前后心率及血压的变化。结果 B、C组镇痛效果与A组比较的差异有统计学意义（P〈0.01）。镇痛后B、C组血压明显降低,心率减慢,与A组比较的差异有统计学意义（P〈0.01）。C组产妇出现运动神经阻滞而A、B组未发现。结论0.20%罗哌卡因对妊娠期高血压病产妇术后镇痛效果确切,能有效降低产妇高血压相关,无运动神经阻滞作用及相关并发症,适合临床应用。     

罗哌卡因与利多卡因术后硬膜外自控镇痛的比较

目的:观察低浓度罗哌卡因与利多卡因行硬膜外自控镇痛的效果。方法:选择ASAⅠ￣Ⅱ级外科中下腹部手术病人60例,随机分为罗哌卡因组(R组)和利多卡因组(L组),选硬膜外麻醉进行手术,手术后使用一次性微量止痛泵行病人自控镇痛(PCEA)。R组:0.2%罗哌卡因,L组:0.5%利多卡因,泵中均加入度冷丁200mg,芬太尼0.3mg,输注速度2ml/h,在镇痛效果差时推注罗哌卡因5ml(未稀释)。分别于镇痛开始后4小时、8小时、12小时、24小时观察并记录镇痛效果及不良反应。结果:两组病人镇痛各时间段VAS评分平均R组为(2.1±0.3)分、L组为(3.8±0.5)分,不良反应无显著性差异。结论:两种方法均可满足病人术后镇痛需要,但罗哌卡因优于利多卡因。     

观察低浓度罗哌卡因—芬太尼用于肛肠科术后镇痛的效果

目的：观察低浓度罗哌卡因复合芬太尼自控硬膜外镇痛（PCEA）的镇痛效果和不良反应。方法：将90例肛肠科术后患者随机分为A、B两组,A组为0.15%罗哌卡因＋0.016%芬太尼混合液,B组为0.2%罗哌卡因＋0.016%芬太尼混合液。于镇痛后6、12、24、48h分别进行视觉模拟评分法（VAS）评分,下肢运动阻滞程度评分（改良Bvomage评分法）。同时监测BP、P、SpO2等不良反应发生情况。结果：B组镇痛后6、12、24、48h（VAS）评分明显低于A组（P均〈0.05）。B组镇痛后双下肢肌力明显低于A组（P〈0.05）。两组6、12、24、48h,BP、P、SpO2没有明显差异,两组恶心、呕吐发生率不明显。24h后拔出导尿管。均可自行排尿和下床活动。结论：低浓度罗哌卡因（0.15%）＋芬太尼硬膜外行肛肠术后镇痛（PECA）均好于高浓度罗哌卡因（0.2%）＋芬太尼混合液,术后镇痛安全可靠。     

吗啡联合罗哌卡因用于硬膜外术后镇痛的临床观察

目的评估罗哌卡因与吗啡合用是否提高硬膜外术后镇痛的效果并减少不良反应。方法80例ASAⅠ—Ⅱ级在连续硬膜外麻醉下施行子宫肌瘤切除术的患者,术后随机分两组,每组40例,Ⅰ组为试验组,将吗啡2mg、罗哌卡因10mg用生理盐水稀释至5ml经硬膜外腔注入,Ⅱ组为对照组,将吗啡2mg用生理盐水稀释至5ml经硬膜外腔注入,拔除导管将患者送回病房,由专人随访术后镇痛时间,镇痛效果及等不良反应发生。结果Ⅰ组镇痛时间明显延长（P〈0．01）,患者皮肤瘙痒,恶心、呕吐的发生率明显低于Ⅱ组。结论吗啡与布托啡诺合用,延长了术后镇痛时问,减少了副作用的发生。     

高乌甲素复合罗哌卡因用于胃肠道病人术后镇痛的效果观察

目的探讨高乌甲素复合罗哌卡因在胃肠道病人术后镇痛的临床效果。方法96例II～III类择期胃肠道手术病人随机分为高乌甲素组、高乌甲素复合罗哌卡因组和芬太尼组,观察三组术后4h、8h、12h、24h、48h镇痛效果及不良反应。结果VAS评分比较高乌甲素组和芬太尼组差异无显著性(P>0.05),高乌甲素复合罗哌卡因组镇痛效果优于单用高乌甲素或芬太尼组,差异有显著性(P<0.05)。高乌甲素组和芬太尼组术后排气时间也无显著差异(P>0.05),高乌甲素复合罗哌卡因组显著早于单用高乌甲素或芬太尼组(P<0.05)。三组都无严重不良反应发生,芬太尼组不良反应发生率稍高于高乌甲素组,但无统计学意义(P>0.05),高乌甲素复合罗哌卡因组不良反应发生率显著减少(P<0.05)。结论高乌甲素复合罗哌卡因是胃肠道病人术后镇痛的理想选择,值得推广。     

不同浓度罗哌卡因术后臂丛神经镇痛效果的观察

目的比较3种不同浓度罗哌卡因伍用吗啡和利多卡因用于上肢手术术后臂丛神经镇痛的效果。方法90例择期上肢手术患者随机分为0.30%罗哌卡因组(Ⅰ组)(含罗派卡因75mg、吗啡1mg、利多卡因200mg、生理盐水15ml),0.25%罗派卡因组(Ⅱ组)(含罗派卡因75mg、吗啡1mg、利多卡因200mg、生理盐水20ml),20%罗哌卡因组(Ⅲ组)(含罗派卡因75mg、吗啡1mg、利多卡因200mg、生理盐水25ml),术后臂丛神经镇痛(PCRA)负荷剂量15ml,总剂量15ml/24h,镇痛时间约50h。以VAS评分比较3组术后PCRA镇痛效果、Bromage评分评定运动阻滞情况。结果术后6、12、24、48hVAS评分,Ⅲ组显著高于Ⅰ、Ⅱ组,Bromage评分Ⅰ组显著高于Ⅱ、Ⅲ组。无明显不良反应。结论0.25%罗哌卡因复合吗啡和利多卡因对上肢手术患者术后镇痛效果确切,适合临床应用。