经静脉电子束CT冠状动脉造影的临床应用

目的 探讨经静脉电子束CT（EBCT）冠状动脉造影的临床应用价值。方法 同期行选择性冠状动脉造影和EBCT冠状动脉造影检查的患者38例，对照选择性冠状动脉造影的结果计算EBCT造影诊断冠心病和冠状动脉狭窄的准确性。结果 （1）EBCT造影可清晰显示和评价共38例152支心外膜冠状动脉中的134支（88．2％），另18支（11．8％）显影不清。左主干全部清晰显示，左前降支，左回旋支和右冠状动脉显影清晰者分别为94．7％，81．6％和76．3％，左主干和前降支显示的比例高于左回旋支和右冠状动脉，统计学上差异有显著性意义（P＜0．05）；（2）EBCT造影诊断冠心病的敏感度，特异度，准确度，阳性和阴性预测值分别为88．0％，84．6％，86．8％，91．7％和78．6％；（3）在38支腔径狭窄≥50％的血管中，EBCT造影低估了其中8支的病变程度，敏感度为78．9％；在96支无明显狭窄的血管中，EBCT造影高估了其中7支的病变程度，特异度为92．7％。结论 经静EBCT冠状动脉造影是1种很有价值的无创性诊断冠心病的方法，其诊断左主干和前降支病变的价值高于右冠状动脉及左回旋支。     

电子束CT血管造影评价冠状动脉狭窄

目的:探讨电子束CT(EBT)血管造影评价冠状动脉狭窄的价值.材料和方法:分析56例经EBT血管造影和常规冠状动脉造影(CAG)检查的资料,将冠状动脉各支分成13个节段与相应CAG结果逐一对照,并进行统计学分析.结果:679个≥2mm的冠状动脉节段中,EBT可评价562个,无法评价117个.EBT对各支冠状动脉的评价准确性依次为左主干、前降支和右冠;对各节段的评价以近段的敏感性、特异性和阴性预测值最高;对不同程度狭窄的评价以＞75%狭窄的诊断最为可靠.此外对正常冠状动脉的诊断准确性也较高,为88.5%.结论:EBT血管造影对评价冠状动脉近段狭窄、重度狭窄和正常血管有很高的价值,可作为CAG术前筛选的常规无创性检查方法.     

MSCT冠状动脉造影的临床应用

目的: 评价多层螺旋CT(MSCT)冠状动脉造影效果及其诊断冠状动脉狭窄的价值.材料和方法:65例临床疑诊冠心病患者作MSCT扫描,所有数据获得在一次屏气中完成.利用心电门控技术,将所得原始图像进行重建,分别对左主干(LMA)、左前降支(LAD)、回旋支(LCA)和右冠状动脉(RCA)及其分支的重建图像进行影像学评价;其中45例同时作常规冠状动脉造影(CAG),以造影结果为金指标,将两种方法所得结果进行对比,了解MSCT冠状动脉造影诊断冠脉狭窄的敏感性和特异性.结果:MSCT冠脉钙化积分诊断冠心病的敏感性79.6%,特异性84.9%;65例共260支血管经MSCT成像,228支(87.7%)可用于影像学评价;各节段冠状动脉重建图像,左主干和前降支近中段显示率最高;CAG发现狭窄49支, MSCT发现狭窄44支.MSCT对冠状动脉狭窄诊断的敏感性83.7%,特异性97.7%.结论: 在控制心率的情况下,MSCT冠状动脉造影可作为诊断冠状动脉狭窄的一种无创筛选检查方法.     

血管内超声及电子束CT检测早期冠状动脉粥样硬化病变程度与冠脉造影的相关研究

目的:比较和评价电子束CT(EBCT)、冠脉内超声(ICUS)及冠状动脉造影(CA)检测冠状动脉粥样硬化病变的初步结果。方法:采用ICUS、EBCT和CAG三种检查方法对10例患者(男7例,女3例,年龄54~75岁,平均65±7岁)的10支靶血管共35个血管段进行成像,逐个血管段比较分析其检测冠脉粥样病变的结果,包括左主干6处,左前降支18处,右冠脉11处。结果:①在CAG正常的19个血管段中,9段(47.4%)ICUS显示存在粥样斑块,斑块面积狭窄百分比(斑块负荷)达(33±14)%(14.5~52.2%),6段(31.6%)EBCT显示有冠脉钙化;②与ICUS相比较,CAG和EBCT诊断冠脉所有粥样病变的总敏感性均为64%,特异性分别为100%和90%,准确性分别为74.3%和71.4%(P=0.763);③EBCT诊断钙化斑块和脂质纤维斑块的敏感性、特异性、阳性预测值、阴性预测值、准确性分别为92.3%、77.3%、70.6%、94.4%、82.9%和33.3%、43.5%、23.5%、55.6%、40%。结论:①对冠脉造影正常血管,ICUS和EBCT均有助于发现冠脉早期病变或者被CAG低估的病变;②以ICUS作为判断冠脉粥样病变的“金标准”,EBCT和CAG对冠状粥样斑块的诊断率相近;③EBCT对钙化病变的检出率较高,对少部分脂肪纤维斑块仍可检出有钙盐沉积。     

统一体位在多层螺旋CT评价冠状动脉狭窄中的应用

目的：通过建立统一的重组图像体位研究多层螺旋CT（MSCT）诊断冠状动脉狭窄的准确性。方法：对55例临床可疑冠心病患者行16层螺旋CT心电门控增强扫描。用舒张期增强扫描图像行统一体位的最大密度投影（MIP）及容积显示技术（VRT）重组，分析应用CT血管成像（CTA）7个MIP重组体位和9个VRT重组体位评价冠状动脉狭窄≥50％的情况，将结果与常规X线冠状动脉造影作对照。结果：共分析55例患者的220个血管分支，常规X线冠状动脉造影发现62个血管分支狭窄≥50％，综合7个MIP重组体位和9个VRT重组体位，CTA发现58个血管分支狭窄≥50％（左主干5个，前降支21个，回旋支14个，右冠状动脉18个）。CTA诊断冠状动脉狭窄≥50％的敏感性为94％（58／62），特异性为92％（146／158），准确率为93％（204／220），阳性预测值83％（58／70），阴性预测值97％（146／150）。结论：MSCT诊断冠状动脉狭窄有较高的敏感性和特异性；建立统一的成像体位有利于CTA与常规x线冠状动脉造影结果对照。     

3.0 T非增强全心冠状动脉MR成像评价冠状动脉狭窄的初步研究

目的 评价3.0T非增强全心冠状动脉MR血管成像(CMRA)诊断冠状动脉狭窄的临床价值.方法 对33例冠状动脉CT血管成像(CCTA)诊断冠状动脉有意义狭窄(＞50％)且拟行冠状动脉造影(CAG)的患者行冠状动脉MR血管成像(CMRA)检查.应用3.0T扫描仪及32通道成像线圈,采用非对比增强、心电门控触发、呼吸导航、T2预置脉冲以及脂肪抑制的三维梯度回波序列.利用美托洛尔降低心率至＜ 80次/min.采用配对样本Wilcoxon秩检验分析CMRA及CCTA在冠状动脉近中段及远段评分的差异性.以CAG结果为金标准,评价CMRA诊断冠状动脉近中段＞50％狭窄的准确性以及与CCTA的一致性.结果 33例患者中30例成功完成CMRA扫描,CMRA及CCTA 在冠状动脉近中段的评分相近[CMRA:(3.49±0.61)分,CCTA:(3.56±0.55)分,Z=-1.715,P＞0.05],CCTA评价冠状动脉远段明显优于CMRA[CMRA:(2.44±0.76)分,CCTA:(3.23±0.60)分,Z=-6.159,P＜0.05].CMRA及CCTA在以段为基础诊断冠状动脉近中段＞50％狭窄的一致性良好(Kappa=0.779,P＜0.05).CMRA诊断的敏感度、特异度、阳性预测值及阴性预测值分别为84.1％ (37/44)、85.8％ (115/134)、66.1％(37/56)、94.3％ (115/122),CCTA分别为88.6％ (39/44)、89.6％ (120/134)、73.6％ (39/53)、96.0％ (120/125).结论 3.0T非增强全心CMRA及CCTA诊断冠状动脉近中段狭窄的准确性相似,但CMRA诊断冠状动脉远段的狭窄需进一步深入研究.     

多层螺旋CT与选择性冠状动脉造影对照研究及其临床应用

目的 评价冠状动脉多层螺旋CT血管造影(MSCTA)的临床应用价值。方法 25例患者均行冠状动脉MSCTA与选择性冠状动脉造影(SCA)，分析右冠状动脉、左冠状动脉主干、前降支和回旋支的通畅性，狭窄发生的部位和严重程度。将MSCTA与SCA结果对照，初步评价MSCTA的临床应用价值。结果 71支MSCTA显示无狭窄的冠状动脉支中，68支与SCA一致；29支显示狭窄的动脉支中，19支与SCA一致。其阴性预测值和阳性预测值分别为95．8％和65．5％；敏感度、特异度和准确度分别为86．4％、87．2％、87，0％。结论 MSCTA作为微创性检查，是评价冠状动脉病变和变异的重要的筛选手段。     

第3代双源CT低剂量Turbo Flash成像图像质量与诊断效能的临床研究

目的探讨第3代双源CT大螺距前瞻性心电门控扫描模式(Turbo Flash)冠状动脉CT成像(CCTA)评价冠状动脉狭窄的准确性、图像质量及有效辐射剂量。方法前瞻性收集2016年4月至2017年4月接受第3代双源CCTA检查的患者1003例,其中有70例患者在CCTA检查后30 d内行冠状动脉造影(CAG)。对冠状动脉各节段图像质量进行评分,计算有效辐射剂量。以CAG结果为“金标准”,计算CCTA显示冠状动脉病变的灵敏度、特异度、阳性预测值和阴性预测值;CCTA与CAG评价冠状动脉狭窄分级的一致性采用Kappa值并进行U检验。结果(1) 图像质量:右冠状动脉不可诊断血管节段为0,左冠状动脉主干及前降支不可诊断血管节段为0,左冠状动脉回旋支不可诊断血管节段为0.04% (3/835)。(2)准确性评价:基于节段水平分析,Force CT诊断冠状动脉狭窄的灵敏度为97.0% (289/298)、特异度为98.3% (706/718)、阳性预测值为96.0% (289/301)、阴性预测值为98.7% (706/715);基于血管分析,灵敏度为97.5% (159/163)、特异度为85.1% (40/47)、阳性预测值为95.8% (159/166)、阴性预测值为90.9% (40/44);基于患者分析,灵敏度、特异度、阳性预测值、阴性预测值均为100%。CCTA与CAG显示的冠状动脉狭窄部位高度一致(U=2.4,P=0.008)。(3)辐射剂量:有效辐射剂量为(1.17±0.29)mSv。结论第3代双源CT Turbo Flash模式可以在自然呼吸、无心率干预下进行冠状动脉成像,扫描成功率高,图像质量佳,评价冠状动脉狭窄的准确性高,有效辐射剂量低。     

64层螺旋CT冠状动脉成像在冠心病诊断中的临床分析

目的 评价64层螺旋CT冠状动脉成像在冠心病(CHD)诊断中应用的临床价值.方法 选择52例疑似CHD患者,以上患者均经64层螺旋CT冠状动脉造影检查与选择性冠状动脉造影(CAG)检查,以CAG检查结果为标准,评价64层螺旋CT冠状动脉造影检查的准确性,同时对冠状动脉病变不同部位和狭窄程度的64层螺旋CT冠状动脉造影检查结果进行分析.结果 上述52例疑似CHD患者CT冠状动脉成像检查准确性94.2％(49/53),敏感性95.3％(41/43),特异性88.9％(8/9),阳性预测值97.6％(41/42)和阴性预测值80.0％(8/10);冠状动脉近端血管的检查结果好于冠状动脉远端血管的检查结果;冠状动脉狭窄程度越重的血管其检查结果好于冠状动脉狭窄程度轻的血管的检查结果.结论 CT冠状动脉成像检查无创、安全、快捷和费用低廉,同时具有较高的灵敏性和特异性的特点,可作为CHD高危人群的普查及CHD治疗后的动态随访的检查方法.     

冠状动脉CT血管成像和运动平板试验对冠心病患者的诊断比较

目的:评价冠状动脉CT血管成像(CCTA)和运动平板试验(TET)对冠心病的诊断价值。方法:以常规冠状动脉造影(CAG)为诊断冠心病(冠脉狭窄≥50%)的"金标准",对同期先后行TET、CCTA和CAG 3种检查的75例疑似冠心病患者进行回顾性分析,将其TET和CCTA的结果与CAG进行比较。结果:TET和CCTA诊断冠心病的敏感度分别为45.2%和90.5%,特异度为69.7%和93.9%,阳性预测值为65.5%和95.0%,阴性预测值为50.0%和88.6%,准确率为56.0%和92.0%,P<0.01。在冠状动脉血管水平CCTA对右冠状动脉、左主干、前降支、回旋支狭窄诊断的准确率分别为86.7%、100.0%、88.0%和76.0%。冠心病患者中TET诊断阳性率与病变血管支数呈正相关(r=0.440,P=0.004);冠心病患者TET诊断结果阳性与阴性仅与血管狭窄程度≥75%狭窄的节段数目有统计学差异(P=0.016)。结论:CCTA诊断冠心病较TET有更高的诊断准确性和较低的诊断假阳性和假阴性,对有症状的疑诊冠心病患者CCTA的诊断具有更重要作用。     

电子束CT血管造影对冠状动脉疾病的诊断与随访

目的评价电子束CT血管造影(EBA)及其三维血管成像技术对冠状动脉疾病的诊断与随访价值. 资料与方法 87例经EBA检查的患者,其中支架置入术后随访16例,搭桥术后随访9例.除9例搭桥患者外,其余78例均有冠状动脉造影(CAG)结果证实. 结果 EBA可评价的冠状动脉中,对左主干和前降支的诊断敏感性、特异性最高,尤其是近段,其次为右冠,对回旋支的诊断敏感性和特异性则较低;16例支架置入术后患者共放置支架47枚,EBA准确定位45枚(95.7%),对支架内开通诊断的符合率为74.5%;9例冠状动脉搭桥术后的患者,共搭建冠状动脉桥血管27支,EBA对桥血管开通与否诊断的符合率为81.5%. 结论 EBA对冠状动脉狭窄的诊断具有较高的术前筛选价值,对术后的随访也有较大的潜力,是一项很有优势的无创性冠心病检查方法.     

Improved accuracy of noninvasive electron beam coronary angiography

OBJECTIVES: We investigated the effect of electrocardiographic (ECG) triggering on the accuracy of coronary electron-beam angiography (EBA) as compared with invasive angiography. METHODS: One hundred thirty-three patients with suspected coronary disease were studied with intravenous coronary EBA and conventional coronary angiography. Patients were divided into 2 groups based upon ECG triggering on the EBA study. Patients were divided into 2 groups based upon different ECG triggering used: 80% R-R interval trigger method (group 1, n = 53) and end-systolic triggering (group 2, n = 80). End-systolic ECG triggering, which started at the end of the T wave in each study, was based on baseline heart rate. RESULTS: Overall sensitivity to detect a > or = 50% luminal stenosis was 69% in group 1 and 91% in group 2 (P = 0.002); specificity was 82% and 94% in group 1 and group 2, respectively (P < 0.001). Using newer triggering techniques (group 2) with EBA, the sensitivity, specificity, and accuracy for patients with disease of the left main coronary artery or 3 vessel disease was 100%, 94%, and 98%, respectively. Nonassessability of coronary segments on 3D-EBA images was reduced from 35% in group 1 to 9% in group 2 patients (P < 0.001). The number of motion-free coronary images increased from 67% to 95% from group 1 to group 2 (P < 0.0001). CONCLUSION: End-systolic ECG triggering improves accuracy, image quality, and assessability of segments of coronary EBA for the detection of angiographic coronary artery disease.     

Image quality of three-dimensional electron beam coronary angiography

PURPOSE: This study identifies reasons for poor image quality and nonassessability of coronary artery segments and compares results between early and late diastolic triggering on coronary electron beam angiography (EBA). METHOD: One hundred patients referred for EBA were studied. Contrast-enhanced transaxial coronary images were acquired using electrocardiographic (ECG) triggering and reconstructed three dimensionally using volume-rendering techniques. The image quality of coronary segments and image artifacts were analyzed statistically. RESULTS: Volume rendering failed in seven patients (7%) owing to cardiac and breathing motions. Image quality was the best with the left main (LM) and worst with the left circumflex (LCX) coronary arteries (p < 0.001). The image quality decreased systematically from proximal to distal within each coronary artery (p < 0.001). Forty percent R-R interval triggering on ECG was better than 80% for image quality. The nonassessable segments occurred in 3% of LM, 2, 8, and 5% of proximal, 24, 22, and 12% of mid, and 64, 45, and 20% of distal segments of the left anterior descending, LCX, and right coronary arteries, respectively (p < 0.05). CONCLUSION: The major limitations of coronary EBA were suboptimal spatial resolution and image artifacts. The image quality could be improved by using optimal ECG triggering.     

Cardiac MRI in ischemic heart disease with severe coronary artery stenosis

RATIONALE AND OBJECTIVES: The aim was to evaluate the left ventricular wall motion abnormalities, perfusion and late contrast enhancement patterns on magnetic resonance imaging (MRI) in patients with 70% or higher degree stenosis or occlusion of coronary arteries on coronary angiography. MATERIALS AND METHODS: Twenty-four patients (5 women, 19 men, age range 38-78, mean age 59.1) who had 70% or higher degree stenosis or occlusion of coronary arteries on coronary angiography who had been referred for cardiac MRI were included. On coronary angiography, 20 vessels were totally occluded [left anterior descending artery (LAD) 12; left circumflex coronary artery (LCx) 2; right coronary artery 6] and 20 vessels were severely stenotic (70-99%). In 5 patients' three vessels, in 6 patients' two vessels, and in 13 patients' a single vessel was involved. Wall motion, perfusion abnormalities, and late contrast enhancement consistent with nonviable myocardium were analyzed at apical, at midventricular, and basal levels on short-axis images of cardiac MRI in concordance with the segmental irrigation areas of the coronary arteries. RESULTS: Impaired perfusion was observed on the corresponding irrigation segments of 39 vessels of 40 coronary artery branches. Wall motion abnormalities were present on corresponding irrigation areas of 30 severely stenotic vessels. Combined evaluation of wall motion and perfusion, segments with the decreased left ventricular contraction, and perfusion matched with the corresponding irrigation areas of all of the 40 stenotic or occluded vessels. CONCLUSION: A correlation was found between the combined assessments of myocardial perfusion, wall motion, and viability on late contrast enhancement on cardiac MRI with the clinical and angiography findings. Thus this combined MRI protocol can be used for the evaluation of ischemic heart disease.     

64层螺旋CT冠状动脉成像诊断冠状动脉疾病的临床应用

目的：探讨64层螺旋CT冠状动脉成像（64SCTCA）诊断冠状动脉中、重度狭窄（管腔直径≥50%）的临床应用价值。方法：收集140例患者64SCTCA的完整资料,依据AHA15段分段法,对有效节段进行评价,并以近期实施的选择性X线冠状动脉造影（CAG）结果为＂金标准＂进行对照分析,了解64SCTCA诊断冠状动脉中、重度狭窄的敏感性、特异性和准确度。结果：所有病例可用于评估的1360节段冠状动脉中,共显示病变284节段,其中272节段得到CAG证实,18节段64SCTCA显示中度狭窄而CAG显示仅为轻度狭窄,6节段64SCTCA显示正常或轻度狭窄而CAG显示中度狭窄,23节段重和中度狭窄的评估两者结果不一致,64SCTCA诊断冠状动脉中、重狭窄的敏感性为95.77%、特异性99.07%、准确度为98.68%。结论：64SCTCA是一种安全可靠且准确有效的冠状动脉检查方法,可作为临床进行CAG检查前的有效筛选手段。     

Dynamic intravenous coronary angiography using 2D monochromatic synchrotron radiation.

A method of examination for coronary artery disease that is less invasive and easier than coronary angiography (CAG) has been sought. We have developed a dynamic intravenous coronary angiography (IVCAG) system using synchrotron radiation (SR) and have used it clinically. Four patients suspected of having angina pectoris underwent IVCAG. An SR beam was reflected asymmetrically with a silicon crystal to produce a wide (150 mm x 80 mm) and monochromatic (37 keV) X-ray beam, with an energy level to achieve high sensitivity to the contrast agent. Following an intravenous injection of contrast agent, irradiation was applied for 4 ms periods at 33 ms intervals for dynamic IVCAG at 30 images s-1. Images were acquired with an image intensifier and recorded with a digital fluorography system. The dynamic images permitted clear visualization of the coronary arteries and permitted evaluation of coronary anatomy. Two patients exhibited no stenotic lesions, one patient had a 90% stenosis in the right coronary artery, and the remaining patient had a 25% stenosis at the site of previous percutaneous transluminal coronary angioplasty in the left anterior descending artery (LAD). The total irradiation doses used for IVCAG were less than those for conventional angiography. Dynamic IVCAG can be readily used for the evaluation of coronary arteries.     

Use of 40-detector row computed tomography before catheter coronary angiography to select early conservative versus early invasive treatment for patients with low-risk acute coronary syndrome

OBJECTIVE: Using catheter coronary angiography (CAG) as reference standard, we examined the agreement of 40-detector row computed tomography (MDCT) in triaging patients into the 2 controversial strategies of managing low-risk acute coronary syndrome (ACS). METHODS: Seventy-eight patients with low-risk ACS received both MDCT and CAG. Early invasive strategy was assigned for the patient if there was significant stenosis (> or =50% diameter stenosis) in any of the coronary artery segments with diameter larger than 1.5 mm. The results of MDCT were compared with the CAG for agreement. RESULTS: The overall agreement of the early conservative/early invasive strategy assignment was 92.3%, with kappa value of 0.82 between MDCT and CAG. Only 1 patient needing early invasive strategy was missed by MDCT. CONCLUSION: Forty-detector row computed tomography is reliable in triaging patients into the 2 strategies of managing low-risk ACS.     

Non-invasive detection of significant coronary artery disease with multi-section computed tomography angiography in patients with suspected coronary artery disease

AIM: The objective of this prospective study was to compare the accuracy of multi-section computed tomography (MSCT) coronary angiography with invasive selective coronary angiography in the detection of significant coronary stenosis (> or =50% lumen diameter narrowing). METHODS: Thirty consecutive patients (mean age 59+/-10 years) with suspected coronary artery disease underwent both invasive coronary angiography and MSCT using a 40-section multidetector row machine with temporal resolution of 53ms. Reconstruction images were performed in eight phases of the cardiac cycle. Images of MSCT and invasive coronary angiography were analysed using the 16-segment model of the American Heart Association. RESULTS: A total of 480 segments from 30 patients were evaluated. Coronary segments distal to a vessel occlusion and segments with coronary stent were not considered for analysis (20 segments in total). Ninety-four (20.4%) segments showed significant (> or =50%) stenosis by invasive coronary angiogram. The accuracy of coronary MSCT was computed on a per segment basis. Average sensitivity, specificity, positive predictive value, and negative predictive value of MSCT were 99, 98, 94, and 99%, respectively. CONCLUSION: This study demonstrated that MSCT is as reliable as coronary angiography at detecting significant obstructive coronary artery disease. In selected groups of patients, it may replace the more invasive and potentially more dangerous conventional coronary angiography.     

磁共振冠状动脉成像定位方法

目的 摸索磁共振冠状动脉成像(MRCA)的扫描定位方法。方法 89例受检者，用快速平衡稳态成像(FIESTA)序列获得标准四腔心位、左室和右室长轴位的电影图像并确定舒张中期触发延迟时间，在此基础上用脂肪抑制的三维FIESTA序列在呼气末屏气定位扫描冠状动脉右支(RCA)、左主干(LM)、前降支(LAD)和回旋支(LCX)，以美国心脏协会(AHA)推荐的冠状动脉解剖分段法评价定位显示的可重复性。结果 86例受检者能够屏气配合完成检查，适用效率为96．63％；9个位置可以稳定地显示冠状动脉各主支，各位置综合对RCA近段和中段(AHA-18、19段)、LM全长(AHA-1、2)、LAD近段和中段(AHA-3、5、7段)，LCX近段(AHA-10段)的显示可重复性为100％；对LAD、LCX和RCA的远段(AHA-9、14、21段)的显示可重复性分别为94．19％、72．09％、96．51％。结论 MRCA定位方法简单实用，可以稳定显示冠状动脉主要分支的近段和中段，初步具备临床应用的价值。     

电子束CT检出冠状动脉钙化及其与心肌灌注显像的对比研究

目的比较电子束ＣＴ（ＥＢＣＴ）检查冠状动脉钙化（ＣＡＣ）及核素心肌灌注显像（ＭＰＩ）评价冠心病（ＣＨＤ）的价值。材料与方法本组５０例均为临床疑诊或确诊为ＣＨＤ患者。所有患者均行ＥＢＣＴ、ＭＰＩ及冠状动脉造影。结果４０例患者共８４支血管冠状动脉造影证实有明显的冠状动脉病变（ＣＡＤ）（狭窄＞５０％），其中１４例为单支病变，８例为双支病变，１８例为三支病变，另有１０例冠状动脉造影正常。ＥＢＣＴ预测ＣＡＤ的敏感性、特异性及准确性为８３％、８０％及８２％，ＭＰＩ预测ＣＡＤ的敏感性、特异性及准确性分别为８５％、８０％及８４％，ＥＢＣＴ与ＭＰＩ的结果间无显著性差异（Ｐ＞０．０５）。ＣＡＣ血管供血区出现心肌缺血者达６５％。结论ＣＡＣ是预测ＣＡＤ的有价值指标。在有症状的人群中ＥＢＣＴ检出ＣＡＣ预测ＣＡＤ的敏感性、特异性及准确性与ＭＰＩ相似。有症状人群中检出ＣＡＣ患者多有心肌缺血或梗死，因此为早期诊断冠心病，应对无症状人群进行筛选。