低温等离子射频消融技术在牙源性角化囊性瘤治疗中的应用

目的:探讨低温等离子射频消融技术联合开窗减压术,治疗下颌骨牙源性角化囊性瘤的疗效。方法 :对16例病变范围>3 cm的下颌骨牙源性角化囊性瘤患者,采用低温等离子射频消融技术消融囊壁组织,并行开窗减压术,术后3、6、12月复查,观察复发率及囊腔缩小情况。结果 :16例下颌骨牙源性角化囊性瘤经低温等离子射频消融技术结合开窗减压术治疗后,均取得较好疗效,临床及影像学检查显示,囊肿周围骨质再生改建,囊腔逐渐缩小。随访时间10~28个月,随访期间未见复发。结论 :低温等离子射频消融技术治疗下颌骨牙源性角化囊性瘤具有简单、微创、并发症少等优势,是治疗下颌骨牙源性角化囊性瘤的一种安全有效的治疗方法。     

减压术治疗下颌骨大型牙源性角化囊肿的临床研究

目的：评价减压术治疗下颌骨大型牙源性角化囊肿的疗效。方法：回顾1999年10月至2004年10月61例经减压术治疗的下颌骨大型角化囊肿病例．随访6个月～5a，进行临床、影像学及病理学检查，在全景片上测量减压术后病灶的长径变化，评价临床疗效．随访观察复发情况：采用SAS6．12统计软件包进行X^2检验，计算Fisher确切慨率。结果：临床及影像学检查显示，囊肿周同骨质再生改建，囊腔逐渐缩小．被推移的下牙槽神经血管束恢复至正常位置，倾斜移位的牙长轴逐渐纠正减乐术后引流期维持6～23个月，中位时间14个月。减压术治疗颌骨大型角化囊肿的有效率为91．8％，单房型角化囊肿的疗效优于多房型，不同年龄组间的有效率在统计学上无显著差异。本组资料随访期间未发现复发。结论：减乐术是治疗下颌骨大型牙源性角化囊肿的有效方法。     

开窗减压术联合刮治术治疗下颌骨大型牙源性角化囊性瘤

目的 观察对下颌骨大型牙源性角化囊性瘤采用一期开窗减压术联合二期刮治术术后骨腔的影像学改变,探讨该术式的可行性.方法 下颌骨大型牙源性角化囊性瘤16例,进行一期开窗减压术联合二期刮治术治疗,定期复查曲面断层X线片,观察骨腔的改变.结果 经过8～16个月的观察,所有患者一期手术后病变骨腔逐渐向开窗部位缩小,骨腔密度逐渐增高,最终在开窗部位形成小骨腔;二期手术后约3个月,病变区骨密度与正常下颌骨一致.随访3～8年,所有病例均未见复发.结论 一期开窗减压术联合二期刮治术是治疗大型下颌骨牙源性角化囊性瘤的可行术式.     

减压术治疗青少年下颌骨大型角化囊性瘤的疗效分析

目的:探讨和评估减压术在青少年下颌骨大型牙源性角化囊性瘤治疗中的应用效果.方法:选择2005年2月-2011年2月15例下颌骨大型牙源性角化囊性瘤患者,平均年龄19.3岁,采用开窗减压术治疗,2～3个月定期随访,复拍全景片.6～12个月随访,复拍CT,囊肿直径缩小至2 cm左右时行二期囊肿刮除术.结果:减压期12～18个月,平均13.6个月.影像学显示囊肿周围新骨再生,平均囊肿缩小比例6个月时为41.5％,12个月时为61.5％,18个月时为81.8％.二期刮除术后随访1～5a,无复发病例.结论:减压术是治疗青少年下颌骨大型牙源性角化囊性瘤的首选方法.     

开窗减压术治疗大型牙源性角化囊性瘤的临床研究

目的 :探讨开窗减压术治疗颌骨大型牙源性角化囊性瘤的临床价值。方法 :对22例牙源性角化囊性瘤进行开窗减压术,定期随访,待囊腔直径缩小至1~2 cm或连续观察3个月无明显变化时,行二期囊肿刮除术。结果:开窗减压期为3~24个月,影像学显示囊腔周围新骨再生,颌骨形态改建。二期刮除术后随访6~48个月,无复发病例。结论:开窗减压术是一种安全、有效微创治疗颌骨大型牙源性角化囊性瘤的方法。     

开窗减压术治疗下颌骨大型囊性病变30例临床报告

目的：通过开窗减压术治疗下颌骨大型囊性病变,探讨其在下颌骨功能性外科中的应用价值。方法：总结2005年10月～2009年10月治疗的30例下颌骨大型囊性病变开窗减压术病例,所有病例均经2年以上随访,根据临床、影像学及病理学检查,评价临床治疗效果。结果：开窗减压术治疗下颌骨大型囊性病变总有效率95%。结论：开窗减压术治疗下颌骨大型囊性病变是保存下颌骨形态及功能的有效方法。     

牙源性角化囊肿袋形术后的骨形成与改建

目的：本研究的目的是评价颌骨牙源性角化囊肿袋形术后骨形成的特点。方法：65例牙源性角化囊肿患者采用袋形术治疗。术后第3和第6个月分别进行临床、x线检查。病变范围广泛或曲面体层片上显示骨皮质破坏的患者补充CT检查。评估囊肿大小、皮质板穿通、下颌管的连续性、囊内牙移位及患区骨密度变化等。结果：在术后3个月,皮质板破坏区的骨连续性重新建立,下颌管的连续性部分恢复,变形的下颌骨呈现改建。囊内含牙随着囊肿的缩小而发生位移或部分萌出。曲面体层片显示,囊肿区骨密度值不断增加,术后3个月46．07％,术后6月达到64．69％。结论：牙源性角化囊肿袋形术后头3个月患区骨再生较快,一部分解剖形态恢复,此后新骨形成相对较慢,骨改建仍在进行。     

53例角化囊性瘤治疗方法的探讨

目的：探讨牙源性角化囊性瘤的治疗方法。方法：分析比较53例角化囊性瘤经囊肿刮除术、开窗减压术2种不同的手术方法治疗的临床效果。结果：53例角化囊性瘤中15例采取刮除术,38例采取开窗减压术,其中13例采用二期行刮除术治愈;随访期内无复发病例。结论：刮除术和开窗减压术均能有效治疗牙源性角化囊性瘤。牙源性角化囊性瘤应根据患者的个体差异制定个体化的治疗方案。     

开窗减压术治疗下颌骨大型囊性病变的临床研究

目的:通过开窗减压术治疗下颌骨大型囊性病变,探索其在下颌骨保存性功能外科中的应用价值。方法:回顾1999年10月～2004年10月治疗的107例下颌骨大型囊性病变开窗减压术病例,测量开窗减压术后病灶长径的变化,随访观察复发情况,评价临床治愈率。结果:开窗减压术治疗下颌骨大型囊性病变的总有效率为87.85%,牙源性角化囊肿的疗效优于囊性成釉细胞瘤,其中单房型角化囊肿疗效优于多房型者,单房或多房型囊性成釉细胞瘤之间疗效没有统计上差异。结论:开窗减压术是治疗颌骨大型囊性病变的有效方法。     

袋形术对牙源性角化囊性瘤受累牙牙周骨组织重建的作用

目的:评价和分析袋形术在牙源性角化囊性瘤受累牙牙周骨组织重建的作用。方法:我院收治的采用袋形术联合刮除术治疗的下颌骨大型KCOT患者12例,采用CBCT测得受累牙暴露于囊腔的长度及受累牙根尖区新生骨质厚度,测量曲面断层KCOT病变的的面积,计算受累牙根周骨质覆盖比,统计分析袋形术后每3个月曲面断层病变面积的减少量与相关受累牙根周新生骨厚度的相关性。结果:12例KCOT患者,56颗受累牙中袋形术前根周骨质平均覆盖比为63.69%,袋形术后49颗暴露根尖完全被新生骨质覆盖,其余7颗未完全覆盖的根尖周骨质平均覆盖比例为80.02%,所有受累牙根尖周骨质覆盖比例为97.50%,每3月曲面断层片上病变面积减少量平均为(2.23±0.94)cm²,每3月通过CBCT测得的受累牙根尖区新生骨质的厚度平均为(1.57±0.72)mm,二者呈明显的线性相关,相关系数r=0.908。结论:袋形术后受累牙牙周骨组织在治疗期间可持续成骨并覆盖受累牙根尖暴露区,受累牙根周新生骨质厚度增加与囊腔缩小率成正相关。     

Surgical management of dentigerous cyst and keratocystic odontogenic tumor in children: a conservative approach and 7-year follow-up

Dentigerous cyst (DC) is one of the most common odontogenic cysts of the jaws and rarely recurs. On the other hand, keratocystic odontogenic tumor (KCOT), formerly known as odontogenic keratocyst (OKC), is considered a benign unicystic or multicystic intraosseous neoplasm and one of the most aggressive odontogenic lesions presenting relatively high recurrence rate and a tendency to invade adjacent tissue. Two cases of these odontogenic lesions occurring in children are presented. They were very similar in clinical and radiographic characteristics, and both were treated by marsupialization. The treatment was chosen in order to preserve the associated permanent teeth with complementary orthodontic treatment to direct eruption of the associated permanent teeth. At 7-years of follow-up, none of the cases showed recurrence.     

Obturator after marsupialization of a recurrence of a radicular cyst of the mandible

The radicular cyst is the most common odontogenic cyst. We present the case of a 51-year-old man with an extended recurrence of a radicular cyst of the mandible that was treated with marsupialization. Subsequently, an obturator was fitted, and in 10 months a resolution (clinically and radiographically) of the cystic cavity was noticed without any signs of recurrence. The marsupialization is a well-established, nonaggressive treatment of large odontogenic cysts and shows advantages in preserving vital structures, with reduced risk of pathological mandibular fractures. The patient, however, must be compliant and accept the prolonged treatment of marsupialization.     

Conservative approach to the treatment of keratocystic odontogenic tumor

The odontogenic keratocyst, also known as the keratocystic odontogenic tumor, is an aggressive, intraosseous lesion of odontogenic origin that presents a high rate of recurrence. Treatment modalities include aggressive surgical procedures and more conservative approaches that significantly influence the lesion's recurrence potential. The purpose of this case report was to demonstrate a conservative approach in the treatment of an extensive keratocystic odontogenic tumor, located in the mandible's posterior region, using decompression and enucleation.     

Frequency of odontogenic cysts and tumors: a systematic review

A systematic review of the literature from 1993 to 2011 was undertaken examining frequency data of the most common odontogenic cysts and tumors. Seven inclusion criteria were met for the paper to be incorporated. In the preliminary search 5231 papers were identified, of these 26 papers met the inclusion criteria. There were 18 297 odontogenic cysts reported. Of these there were 9982 (54.6%) radicular cysts, 3772 (20.6%) dentigerous cysts and 2145 (11.7%) keratocystic odontogenic tumors. With the reclassification of keratocystic odontogenic tumor in 2005 as an odontogenic tumor, there were 8129 odontogenic tumors reported with 3001 (36.9%) ameloblastomas, 1163 (14.3%) keratocystic odontogenic tumors, 533 (6.5%) odontogenic myxomas, 337 (4.1%) adenomatoid odontogenic tumors and 127 (1.6%) ameloblastic fibromas. This systematic review found that odontogenic cysts are 2.25 times more frequent than odontogenic tumors. The most frequent odontogenic cyst and tumor were the radicular cyst and ameloblastoma respectively.     

牙源性角化囊肿的手术治疗：保守性或根治性方法

牙源性角化囊肿（odontogenic keratocyst，OKC）因其侵袭性行为、组织学和遗传学方面的新发现，在WHO的分类中已命名为牙源性角化囊性瘤（keratocystic odontogenic tumour，KCOT）。本文复习了这种病变的生物学特点，并结合笔者的研究经验和相关文献资料分别介绍保守性和根治性治疗策略。     

Trattamento chirurgico di una cisti odontogena gigante associata a terzo molare inferiore incluso,follow-up a 2 anni

Objectives

The aim of this case report is to describe the surgical approach to a large keratocystic odontogenic tumor associated with impacted lower third molar. The considerable size of the cyst and its adjacency to noble anatomical structures make the surgery more complex.

Materials and methods

The authors present a case of large keratocystic odontogenic tumor associated with impacted third molar, located in the right mandibular ramus.Cystectomy intervention with vestibular access was selected in order to preserve surrounding healthy tissues and to extract, at the same time, the impacted tooth. Histological analysis had previously allowed the initial diagnosis of keratocystic odontogenic tumor.

Results

Postoperative radiograph, performed 2 years after the cystectomy intervention, showed complete bone regeneration. Neither neurological complications, nor cyst recurrence occurred.

Conclusions

The presented surgical intervention allowed the cyst removal without any damage to surrounding anatomical structures.     

Solid variant of keratocystic odontogenic tumor with ameloblastomatous transformation: a case report and review of the literature

The solid variant of keratocystic odontogenic tumor is an extremely rare tumor. Its clinical and pathologic features remain poorly defined, even in the 2005 World Health Organization odontogenic tumor classification. We report an unusual lesion in a 38-year-old female Chinese patient. The lesion demonstrated the solid or multiple cystic architecture of a keratocystic odontogenic tumor, but also exhibited ameloblastomalike lining epithelium in some areas. The complex histopathology made a pathologic diagnosis difficult. Finally, the lesion was diagnosed as solid variant of keratocystic odontogenic tumor with ameloblastomatous transformation. We present the clinical and pathologic details of the case, and review the relevant literature.