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1.
颅内后循环动脉瘤的临床特征及显微外科治疗   总被引:1,自引:1,他引:0  
目的 探讨颅内后循环动脉瘤的临床特征、显微外科治疗的方法及其效果.方法 对2000年1月至2008年10月手术治疗的10例颅内后循环动脉瘤的临床资料进行回顾分析.结果 动脉瘤位于基底动脉分叉部4例,大脑后动脉P1-P2交界处2例,小脑后下动脉3例,小脑前下动脉1例.以蛛网膜下腔出血为临床表现者8例,以脑神经麻痹等占位效应为表现者2例;8例行单纯动脉瘤夹闭术,2例行动脉瘤夹闭及残颈包裹术.术后随访6个月至8年,恢复良好6例,中度伤残2例,重度残疾1例,死亡1例.结论 后循环动脉瘤手术较为困难,应选择合适的入路,充分显露动脉瘤和载瘤动脉,术中尽可能保护脑干、脑干穿支动脉及脑神经,以减少手术后致死致残率.  相似文献   

2.
自膨胀颅内专用支架治疗大脑中动脉宽颈动脉瘤   总被引:2,自引:0,他引:2  
目的评价自膨胀颅内支架治疗大脑中动脉宽颈动脉瘤的可行性、有效性及安全性。方法回顾性分析采用颅内自膨胀支架治疗16例16个大脑中动脉动脉瘤病人的临床资料。动脉瘤破裂10例,未破裂5例,复发1例;采用单纯支架治疗3例,支架结合弹簧圈栓塞13例。结果本组支架均成功释放。13例采用支架结合弹簧圈治疗的病人中,动脉瘤致密栓塞9例,瘤颈残留1例,瘤体显影3例。术后发生手术相关并发症1例(大脑中动脉上千闭塞,但无临床症状)。出院时改良Rankin评分(MRS评分)0-2分14例。4分1例,6分1例。本组均获临床随访,平均随访18.7个月;无新发神经系统症状,未发生动脉瘤再次破裂出血。9例行影像学随访,平均随访5.8个月;动脉瘤均保持稳定或改善,载瘤动脉无支架内狭窄。结论自膨胀颅内支架治疗大脑中动脉宽颈动脉瘤技术上可行,安全性高。即刻栓塞结果满意;但长期疗效仍有待进一步随访。  相似文献   

3.
BACKGROUND AND PURPOSE: We sought to describe the clinical outcome and angiographic results obtained in the endovascular therapy of ruptured posterior circulation cerebral aneurysms using Guglielmi detachable coils (GDC) over a 7-year period. METHODS: A retrospective analysis was performed of 112 patients evaluated at the University of California at San Francisco Medical Center between June 1991 and August 1998. The Hunt-Hess grade at presentation of treated patients was I in 26 patients (24%), II in 24 (22%), III in 27 (25%), IV in 24 (22%), and V in 8 (7%). Clinical follow-up for the total population was achieved in 104 of 109 patients (96%), with a mean duration of 13.1 months. Angiographic follow-up for the subset excluding parent vessel occlusion cases was obtained in 93% of cases, with a mean duration of 7.2 months. RESULTS: Technical success, defined as the ability to catheterize and embolize the aneurysm with GDC, was achieved in 109 of 112 of cases (97%). The mean angiographic occlusion rate, or projected area of the aneurysm occluded by the coils, for all 110 successfully treated aneurysms was 94.6%. At latest clinical follow-up, 81 of 109 patients (74%) achieved good recovery with Glasgow Outcome Scale (GOS) score of I, 10 of 109 (9%) were moderately (GOS II) and 5 of 109 (5%) were severely (GOS III) disabled, 1 of 109 (1%) remained in a vegetative state (GOS IV), and 12 of 109 (11%) were dead. Of the subset of 77 patients with Hunt-Hess grades I to III, 68 (88%) achieved a good clinical outcome (GOS I). A statistically significant correlation was demonstrated between Hunt-Hess grade at presentation and final GOS outcome score (chi(2)=41.4, P<0.0005). Procedure-related permanent morbidity was 2.8% (3/109 patients). Repeated hemorrhage was observed in a single patient (0.9%) with a partially treated aneurysm. CONCLUSIONS: The observed favorable outcome and low morbidity in this group of high-risk patients point to GDC embolization as an effective method for the endovascular management of patients with ruptured posterior circulation aneurysms.  相似文献   

4.
目的 报道儿童颅内动脉瘤血管内治疗的特征和血管内治疗的结果.方法 2002-2006年收治29例儿童动脉瘤患者(年龄<19岁);其中14例蛛网膜下腔出血,10例意外发现,2例脑神经麻痹,3例神经功能障碍.动脉瘤的位置:10个椎动脉动脉瘤,5个大脑中动脉瘤,4个大脑后动脉瘤,3个基底动脉动脉瘤,3个前交通动脉瘤,1个小脑后下动脉瘤,2个大脑前动脉瘤,1个颈内动脉动脉瘤.结果 7例动脉瘤行动脉瘤囊内弹簧圈栓塞,17例载瘤动脉闭塞(9例使用球囊闭塞载瘤动脉,8例使用弹簧圈载瘤动脉闭塞).1例椎动脉瘤病人全脑血管造影后4 d动脉瘤白发血栓形成.4例行支架或者支架辅助弹簧圈栓塞动脉瘤(其中2例基底动脉瘤患者死亡,2例动脉瘤栓塞后复发并再次给予栓塞治疗).平均随访20.7个月,93.1%的病人GOS评分4分或5分.结论 儿童颅内动脉瘤在发病特点上,男性比女性多见,好发部位是椎动脉、大脑后动脉和人脑中动脉.对于梭形动脉瘤行载瘤动脉闭寒是一种安全有效的治疗方法.基底动脉主十的梭形动脉瘤治疗困难而且死亡率高.  相似文献   

5.
目的 总结无蛛网膜下腔出血(SAH)的破裂脑动脉瘤的诊治经验.方法 对15例在起病后2 d内首次CT或MRI上表现为脑内出血(ICH),和(或)脑室内出血(IVH)、硬脑膜下血肿(SDH)和壁间出血(IMH)而无SAH的破裂脑动脉瘤患者的临床表现、影像学检查结果 、治疗方法 和预后进行回顾性分析.结果 本组首次CT或MRI检查表现为ICH者3例、IVH合并ICH者6例、SDH者1例、IVH者1例、IMH者3例和等高混合密度者1例.其中动脉瘤位于大脑中动脉6例、前交通动脉4例、后交通动脉3例、大脑前动脉1例和小脑后下动脉1例.开颅手术夹闭动脉瘤13例,血管内栓塞2例.出院时GOS评分:恢复良好8例、中残3例、重残3例和植物生存1例.本组15例占同期破裂脑动脉瘤的3.8%.结论 破裂脑动脉瘤首次CT扫描可表现为单纯ICH,和(或)IVH、SDH、IMH而无SAH,与CT扫描时间、动脉瘤的部位和指向以及出血量有关.早期控制颅内高压、及时诊断和有效处理破裂动脉瘤,是改善预后的关键.  相似文献   

6.
ABSTRACT

Objectives: Basilar artery trunk aneurysms (BTAs) are a rare pathology and difficult to treat. We present our experience regarding angiographic results and clinical outcomes for 16 BTAs treated by reconstructive endovascular treatment (EVT) using stent or balloon.

Methods: Between January 2003 and December 2014, 15 patients (mean age, 58.6 years; 11 males) with 16 BTAs were enrolled. Clinical manifestation, outcomes and procedural complications were evaluated retrospectively, and follow-up angiography was performed 12 and 24 months after procedure.

Results: Subarachnoid hemorrhage (SAH) developed in seven aneurysms and nine were found incidentally. In one case, SAH followed by acute infarction on pons. The location of the aneurysms was the pure basilar artery (BA) trunk in 13 and the junction of the BA and the superior cerebellar artery in 3. Reconstructive EVT was technically successful in 15 aneurysms (93.8%) and failed in one due to the difficulty of vascular access. Stent/balloon-assisted coiling was performed in 13 aneurysms and sole stent therapy in two aneurysms. One patient had periprocedural complication of acute in-stent thrombosis. All treated patients had no symptoms with the usual activities except three patients, who died from myocardial infarction, aneurysmal rebleeding, and cerebellar infarction. Angiographic follow-up was performed in nine aneurysms; three aneurysms were recanalized (33.3%) and six aneurysms had no interval change (66.7%). There was no significant event during the follow-up period (mean, 23.5 months).

Conclusion: In the treatment of BTAs, reconstructive EVT may provide a feasible and safe option to microsurgery.  相似文献   

7.
目的 探讨血管内治疗后循环动脉瘤的安全性和可行性.方法 本组收治后循环动脉瘤47例,其中基底动脉顶端动脉瘤25例,小脑上动脉瘤4例,小脑后下动脉瘤5例、小脑前下动脉瘤2例,椎动脉解离性动脉瘤9例,多发动脉瘤2例,其中23例采用微弹簧圈栓塞治疗,7例采用球囊辅助微弹簧圈栓塞,16例采用Neuroform支架结合微弹簧圈治疗,1例椎动脉小宽颈动脉瘤采用单纯Neuroform支架瘤颈成形术.结果 100%栓塞37例,95%栓塞9例.死亡1例.短期随访无再次蛛网膜下腔出血,5例复查脑血管造影,显示载瘤动脉通畅,动脉瘤无复发,1例单纯支架成形患者复查造影动脉瘤消失.结论 血管内治疗是治疗后循环动脉瘤的安全有效的治疗手段,对于宽颈动脉瘤应采用球囊辅助或支架成形栓塞以提高栓塞率.  相似文献   

8.
目的探讨大脑中动脉(MCA)动脉瘤的临床特点及手术方法。方法回顾性分析108例MCA动脉瘤的临床特点、影像学特征及手术方法。9例未破裂动脉瘤MRI检查表现为中颅窝占位,99例破裂动脉瘤CT检查均示蛛网膜下腔出血。入院时患者Hunt—Hess分级:0级9例,I级3例,Ⅱ级21例,Ⅲ级58例,Ⅳ级15例,V级2例。脑血管造影提示MCA主干动脉瘤10例,分叉部92例,MCA远端6例,均经改良翼点入路进行手术。结果动脉瘤夹闭93例,动脉瘤切除7例,夹闭加包裹8例。2例术前Hunt—Hess分级V级病人,术后1例死亡,1例植物生存;术前Hunt—Hess分级Ⅳ级的15例病人中,11例长期昏迷。随访6~36个月,平均随访14-3个月,按照GOS评定预后,其中5分为40例,4分48例,3分7例,2分12例,1分1例。结论MCA动脉瘤的治疗首选动脉瘤夹闭术,术中保护MCA及保持周围相关血管的通畅是手术的关键。  相似文献   

9.
目的:回顾性分析并探讨颅内后循环动脉瘤的临床表现和手术人路。方法:后循环动脉瘤22例,占同期颅内动脉瘤的10.3%,其中大脑后动脉瘤12例,基底动脉瘤6例,脉络膜后动脉远端动脉瘤2例,小脑前下动脉和小脑后下动脉瘤各1例。蛛网膜下腔出血15例(68.2%),其它表现为脑干和脑神经损害症状。18例经显微手术,主要经翼点人路和颞下经小脑幕人路。2例栓塞治疗,2例因病人拒绝未治。结果:动脉瘤夹闭加切除10例,孤立加切除6例,包裹2例,血管内治疗2例。18例优良,2例轻残,无手术死亡。结论:后循环动脉瘤大多瘤体较大,瘤内多含血栓。翼点人路对基底动脉远端、大脑后动脉P_(1 2)段动脉瘤显露优良,颞下入路用于夹闭大脑后动脉P_(2~3)段动脉瘤,显露优良。  相似文献   

10.
目的 探讨小脑后下动脉瘤的临床特点及手术方法 .方法 回顾性分析21例小脑后下动脉瘤的临床特点、影像学特征及手术方法 .其中男9例,女12例,平均40.6岁.1例表现为后颅窝占位;20例为动脉瘤破裂出血.入院时患者Hunt-Hess分级:Ⅰ级1例,Ⅱ级14例,Ⅲ级5例,Ⅳ级1例.头颅CT表现为幕下为主的蛛网膜下腔出血,或第四脑室出血或二者兼有.脑血管造影提示小脑后下动脉近端动脉瘤13例,远端动脉瘤8例,分别采用枕下旁正中及枕下正中入路进行手术.结果 19例行动脉瘤蒂夹闭术,1例行孤立术,1例行载瘤动脉近端切断术.3例术后出现切口一过性脑脊液漏;1例术后偏瘫、后组脑神经麻痹和长期昏迷,2例轻度后组脑神经受损,3个月后完全恢复;其余患者术后无神经功能损伤或并发症,恢复良好.结论 小脑后下动脉瘤的治疗首选动脉瘤夹闭术,术中保护后组脑神经和后下动脉是手术的关键.  相似文献   

11.
Infraoptic course of the precommunicating segment of the anterior cerebral artery (A1) is a rare anomaly. Furthermore, the presence of this anomaly associated with persistent trigeminal artery variant has been reported in the literature only once. We present a patient who had infraoptic course of A1 associated with an ipsilateral persistent trigeminal artery variant arising from the right internal carotid artery with no apparent connection to the basilar artery. The persistent trigeminal artery variant supplied to the right posteroinferior cerebellar artery territory. The patient also had hypoplastic left vertebral artery, superior cerebellar arteries originating from posterior cerebellar arteries bilaterally, and a bilobed aneurysm of the anterior communicating artery. The aneurysm was clipped and the infraoptic course was verified during the surgery. The post-operative course was uneventful and a follow-up arteriogram on the 7th postoperative day revealed successful obliteration of the aneurysm.We reviewed the literature with respect to presentation, associated vascular anomalies, imaging, associated cerebral aneurysms and other cerebral abnormalities, and treatment of the associated aneurysms. A discussion of the embryogenesis of this rare anomaly is also provided.  相似文献   

12.
目的 探讨复合手术治疗颅内破裂动脉瘤合并脑内血肿的疗效。方法 回顾性分析簧圈栓塞术后行颅骨钻孔血肿腔引流术治疗的5例颅内破裂动脉瘤合并脑内血肿的临床资料。结果 5例头颅CT均表现为典型蛛网膜下腔出血(SAH)合并脑内血肿;DSA发现动脉瘤位于大脑前动脉A2段分叉部1例、大脑前动脉A2段1例、前交通动脉1例、颈内动脉后交通动脉1例、大脑中动脉分叉部1例;术前Hunt-Hess分级Ⅱ级2例,Ⅲ级2例,Ⅳ级1例。引流术后3~4 d血肿大部分引流干净,无再出血、感染及脑梗死。术后6个月GOS评分3分1例,4分1例,5分3例。结论 对合并脑内血肿的自发性SAH,首先应考虑动脉瘤破裂出血可能,需尽早行DSA检查明确诊断;复合手术对于部分未发生脑疝又合并脑内血肿的破裂动脉瘤是可行的,能取得良好的疗效。  相似文献   

13.
14.
The etiologies of intracranial artery dissection are various, the exogenous as well as inherited connective tissue disorders. We report on a patient who presented with diffuse subarachnoid hemorrhage who had been suffered from essential thrombocythemia. He was diagnosed to multiple dissecting aneurysms of left superior cerebellar artery, left posterior inferior cerebellar artery and right pericallosal artery and treated with endovascular coil embolization.  相似文献   

15.
Aneurysms arising from the distal portion of superior cerebellar artery are infrequently seen. They are usually assumed to result from local arterial wall disruption like proximal supratentorial artery aneurysms. Depending on institutional facilities, these particular aneurysms can be treated either by a microsurgical procedure or interventional radiological technique. In general, surgical clipping has been recommended for these lesions. In this report we describe a 44-year old man who presented with a subarachnoid hemorrhage in the right cerebellopontine angle and was diagnosed with a giant aneurysm arising from the cisternal portion of the right superior cerebellar artery. The patient underwent surgery; microsurgical clipping of the aneurysm through subtemporal craniotomy was performed with no difficulty. We conclude that surgical therapy is suitable for the majority of aneurysms arising from the distal portion of the superior cerebellar artery.  相似文献   

16.
目的探讨不同手术方式治疗小脑后下动脉动脉瘤的临床疗效。方法回顾性分析2014年10月至2017年5月威海市中心医院神经外科收治的36例小脑后下动脉动脉瘤患者(共36个动脉瘤)的临床资料。36例患者中,行单纯介入栓塞22例,行单纯开颅手术夹闭9例,5例行开颅血管搭桥联合介入栓塞手术。以出院时格拉斯哥预后评级(GOS)评估手术治疗效果,采用改良Rankin量表评分(mRS)评估患者的临床结局。通过数字减影血管造影(DSA)或CT血管成像(CTA)评估影像学结局。结果行单纯介入栓塞的22例患者中,完全栓塞21例;行单纯开颅手术夹闭的9例患者中,成功夹闭8例;5例应用开颅血管搭桥联合介入栓塞的患者均成功吻合血管并达到完全栓塞。36例患者中,9例术后存在非新发的神经功能缺失,1例术后死亡。35例患者出院时的GOS为:Ⅴ级18例,Ⅳ级14例,Ⅲ级3例。35例患者术后2周复查CTA或DSA,显示动脉瘤均消失。术后3~12个月的影像学随访结果显示,动脉瘤复发3例(8.6%),均为行介入栓塞的患者;其余32例未见动脉瘤复发。34例获临床随访1年,mRS 0~1分21例,2分8例,3分3例,4分1例,5分1例,预后良好率为85.3%(29/34);失访1例。结论根据具体病情采用介入栓塞术、开颅夹闭术或开颅血管搭桥联合介入栓塞治疗小脑后下动脉动脉瘤,患者的临床预后较好,动脉瘤复发率低。  相似文献   

17.
后循环动脉瘤显微外科手术治疗   总被引:1,自引:1,他引:0  
目的 探讨后循环动脉瘤手术适应证和治疗效果.方法 纳入42例共44个后循环动脉瘤,包括基底动脉动脉瘤26例(27个)、椎动脉动脉瘤16例(17个).其中15例分别行颈外动脉-大脑后动脉P2段(4例)、颈内动脉-大脑后动脉P2段(2例)、颌内动脉-大脑后动脉P2段(2例)、椎动脉颅内外段(2例)、枕动脉.小脑后下小动脉(5例)搭桥联合动脉瘤孤立术;余27例行单纯动脉瘤夹闭术.结果 经随访共37例(基底动脉顶端动脉瘤14例、基底动脉主干动脉瘤3例、椎动脉动脉瘤9例、小脑后下动脉动脉瘤5例、大脑后动脉P1~P2段交界处动脉瘤4例、小脑上动脉动脉瘤l例和小脑前下动脉动脉瘤1例)患者恢复正常生活活动能力,无一例发生手术相关性神经功能障碍,恢复良好率达88.09%.其余5例患者,1例(基底动脉顶端动脉瘤)术后出现严重神经功能缺损症状与体征,生活不能自理;2例(1例基底动脉顶端动脉瘤、1例基底动脉主干动脉瘤)因术后发生脑干缺血,围手术期死亡;2例(椎动脉动脉瘤)复发患者经再次治疗康复.结论 对于不宜直接行手术夹闭的后循环动脉瘤,为了避免因夹闭动脉瘤和延长临时阻断载瘤动脉时间而发生术后脑缺血事件.可选择颅内外血管搭桥联合动脉瘤孤立术,以避免动脉瘤夹闭术带来的危险.  相似文献   

18.

Objective

The standard treatment strategy of intracranial aneurysms includes either endovascular coiling or microsurgical clipping. In certain situations such as in giant or dissecting aneurysms, bypass surgery followed by proximal occlusion or trapping of parent artery is required.

Methods

The authors assessed the result of extracranial-intracranial (EC-IC) bypass surgery in the treatment of complex intracranial aneurysms in one institute between 2003 and 2007 retrospectively to propose its role as treatment modality. The outcomes of 15 patients with complex aneurysms treated during the last 5 years were reviewed. Six male and 9 female patients, aged 14 to 76 years, presented with symptoms related to hemorrhage in 6 cases, transient ischemic attack (TIA) in 2 unruptured cases, and permanent infarction in one, and compressive symptoms in 3 cases. Aneurysms were mainly in the internal carotid artery (ICA) in 11 cases, middle cerebral artery (MCA) in 2, posterior cerebral artery (PCA) in one and posterior inferior cerebellar artery (PICA) in one case.

Results

The types of aneurysms were 8 cases of large to giant size aneurysms, 5 cases of ICA blood blister-like aneurysms, one dissecting aneurysm, and one pseudoaneurysm related to trauma. High-flow bypass surgery was done in 6 cases with radial artery graft (RAG) in five and saphenous vein graft (SVG) in one. Low-flow bypass was done in nine cases using superficial temporal artery (STA) in eight and occipital artery (OA) in one case. Parent artery occlusion was performed with clipping in 9 patients, with coiling in 4, and with balloon plus coil in 1. Direct aneurysm clip was done in one case. The follow up period ranged from 2 to 48 months (mean 15.0 months). There was no mortality case. The long-term clinical outcome measured by Glasgow outcome scale (GOS) showed good or excellent outcome in 13/15. The overall surgery related morbidity was 20% (3/15) including 2 emergency bypass surgeries due to unexpected parent artery occlusion during direct clipping procedure. The short-term postoperative bypass graft patency rates were 100% but the long-term bypass patency rates were 86.7% (13/15). Nonetheless, there was no bypass surgery related morbidity due to occlusion of the graft.

Conclusion

Revascularization technique is a pivotal armament in managing complex aneurysms and scrupulous prior planning is essential to successful outcomes.  相似文献   

19.
研究背景小脑前下动脉动脉瘤临床罕见,破裂出血后果严重。本文回顾分析12例小脑前下动脉动脉瘤患者(共13个动脉瘤)的临床诊断与治疗经过,分析总结其临床特点、影像学表现、手术方法及预后,以为临床提供参考。方法回顾分析2004年6月-2012年6月治疗的小脑前下动脉动脉瘤患者的临床资料。结果 12例共13个动脉瘤,约占同期颅内动脉瘤总病例数的0.19%(12/6467),平均年龄54岁。动脉瘤形态以囊状居多(10个),梭形少见(3个);分别位于小脑前下动脉起始部即小脑前下动脉基底动脉交界处(3个)、内听道前段(3个,均位于小脑前下动脉第一分叉部)、内听道段(3个)和内听道后段(4个);动脉瘤直径平均为3.90mm。其中3例(4个动脉瘤)行外科手术治疗[动脉瘤夹闭术(2例)、孤立术(1例)],其余9例均行血管内治疗(动脉瘤栓塞术2例、支架辅助动脉瘤栓塞术3例、动脉瘤和载瘤动脉闭塞术4例)。术后并发症包括面瘫(1例)、吞咽困难伴饮水呛咳(1例)和双眼对侧视野缺损(1例);平均随访36.41个月,Glasgow预后分级3分1例、4分2例、5分9例,均达良好标准。结论小脑前下动脉动脉瘤临床罕见,外科手术治疗者需综合评价手术夹闭与血管内治疗适应证,从而选择最佳治疗方法。  相似文献   

20.

Objective

Surgical clipping and coil embolization of distally located intracranial aneurysms can be challenging. The goal of this study was to assess the feasibility, safety and efficacy of treatment of distal aneurysms with the liquid embolic agent Onyx 18/34.

Methods

Sixteen patients were treated with Onyx 18/34 for distally located aneurysms in our institution between March 2009 and September 2012. The technique consists of occluding the aneurysm as well as the parent vessel at the level of aneurysm with Onyx 18 or 34. Candidates for this treatment were patients with distal aneurysms including mycotic aneurysms, dissecting aneurysms, and pseudoaneurysms in which coiling was considered impossible.

Results

Of the 16 patients, 12 presented with subarachnoid and/or intracerebral hemorrhage. Median aneurysm size was 4.6 mm. Aneurysm locations were as follows: Posterior inferior cerebellar artery (n = 5), distal anterior inferior cerebellar artery (n = 3), distal pericallosal (n = 3), distal anterior cerebral artery (n = 3), lenticulostriate artery (n = 1), and anterior ethmoidal artery (n = 1). There were 4 mycotic aneurysms. Complete aneurysm obliteration was achieved in all 6 patients with available angiographic follow-up. There was only 1 (6.3%) symptomatic complication in the series. There were no instances of reflux or accidental migration of embolic material. Favorable outcomes were noted in 82% of patients at discharge. Two patients with mycotic aneurysms died from cardiac complications of endocarditis. No aneurysm recanalization or rehemorrhage were seen.

Conclusion

Parent vessel trapping with Onyx 18/34 offers a simple, safe, and effective means of achieving obliteration of distal challenging aneurysms.  相似文献   

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