共查询到20条相似文献,搜索用时 13 毫秒
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Cancan Yuan Yiwen Ding Keruo Zhou Yuankai Huang Xiaoyu Xi 《Health & social care in the community》2019,27(5):e567-e587
Community pharmacy services (CPS) have been shown to be positive in many disease management and patient care programs, but clinical outcomes were followed by process indicators and methodological flaws in previous researches made it difficult to prove the effectiveness of clinical outcomes of CPS. Therefore, this study attempted to review the clinical outcomes of CPS. Interventions included are provision of medication review, patient education, adherence assessment, health/lifestyle advice, physical assessment, monitoring, prescribing, or adjusting and administering therapy from community pharmacists. By searching for key words like community pharmacists, pharmaceutical services, clinical outcomes in MEDLINE and EMBASE and manually searching (up to June 2017), 1910 studies investigating the clinical outcomes of CPS were obtained. After screening the titles, abstracts and full texts for relevancy, 52 researches with controlled groups were included and assessed for methodological quality. Finally, 25 studies were selected for the meta‐analysis based on their common endpoints: systolic blood pressure, diastolic blood pressure and glycosylated haemoglobin. The Cochrane tool was used to assess the risk of bias. Chi‐square and I‐square tests were performed to assess heterogeneity, and the weighted mean differences were estimated using random effect models. Of the 52 articles, 47 studies demonstrated that CPS had positive clinical outcomes, 3 studies showed mixed outcomes and 2 studies revealed no effects. In the meta‐analysis, intervention groups displayed greater reductions in systolic BP (95% CI: ?8.198–2.356), diastolic BP (95% CI: ?3.648–0.645) and HbA1c (95% CI: ?0.905–0.224) than usual care groups. CPS have positive clinical outcomes, particularly significant reductions in systolic BP, diastolic BP and HbA1c. It was difficult to find out which intervention(s) of CPS directly led to certain changes and influence of CPS might be underestimated for only three common surrogate endpoints. More researches should be conducted with sufficient data. 相似文献
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Identification of gaps in the current knowledge on pulmonary hypertension in extremely preterm infants: A systematic review and meta‐analysis 下载免费PDF全文
Sanne Arjaans Elvira A. H. Zwart Mark‐Jan Ploegstra Arend F. Bos Elisabeth M. W. Kooi Hans L. Hillege Rolf M. F. Berger 《Paediatric and perinatal epidemiology》2018,32(3):258-267
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Anna Chu Julia E. Heck Karina Braga Ribeiro Paul Brennan Paolo Boffetta Patricia Buffler Rayjean J. Hung 《Paediatric and perinatal epidemiology》2010,24(5):449-469
Chu A, Heck JE, Ribeiro KB, Brennan P, Boffetta P, Buffler P, Hung RJ. Wilms' tumour: a systematic review of risk factors and meta‐analysis. Paediatric and Perinatal Epidemiology 2010. Wilms' tumour comprises 95% of all renal cancers among children less than 15 years of age. The purpose of this review is to examine the existing literature on perinatal and environmental risk factors for Wilms' tumour. A search for epidemiological studies that examined risk factors for Wilms' tumour was undertaken in Medline, LILACS, ISI Web of Science and Dissertation Abstracts. A total of 37 studies, including 14 cohort, 21 case–control and 2 case–cohort studies, were identified that examined environmental and perinatal risk factors. Most studies were from Western Europe and North America, and among case–control studies, 16 used randomly selected population‐based controls. We observed a significantly increased risk of Wilms' tumour with maternal exposure to pesticides prior to the child's birth (OR = 1.37 [95% CI 1.09, 1.73]), high birthweight (OR = 1.36 [95% CI 1.12, 1.64]) and preterm birth (OR = 1.44 [95% CI 1.14, 1.81]), although the results regarding pesticide exposure may be subject to publication bias (Egger's test, P = 0.09). Further analyses to adjust for the heterogeneity in the results for high birthweight and preterm birth did not statistically change the significance of the results. Additionally, an increased though not statistically significant risk of Wilms' tumour was associated with maternal hypertension (OR = 1.30 [95% CI 0.99, 1.72]), and, compared with the first born, being a second or later birth was associated with a significantly decreased risk (OR = 0.82 [95% CI 0.71, 0.95]). This review suggests a role for several perinatal and environmental risk factors in the aetiology of Wilms' tumour. 相似文献
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The risk of eating disorders comorbid with attention‐deficit/hyperactivity disorder: A systematic review and meta‐analysis 下载免费PDF全文
Bruno Palazzo Nazar MD MSc Camila Bernardes BA Gemma Peachey MBBS Joseph Sergeant PhD Paulo Mattos MD MSc PhD Janet Treasure OBE PhD FRCP FAED 《The International journal of eating disorders》2016,49(12):1045-1057
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A meta‐analysis of the relation between therapeutic alliance and treatment outcome in eating disorders 下载免费PDF全文
Tiffany A. Graves MA Nassim Tabri PhD Heather Thompson‐Brenner PhD Debra L. Franko PhD Kamryn T. Eddy PhD Stephanie Bourion‐Bedes MD Amy Brown PhD Michael J. Constantino PhD Christoph Flückiger PhD Sarah Forsberg PsyD Leanna Isserlin MD Jennifer Couturier MD Gunilla Paulson Karlsson MD Johannes Mander PhD Martin Teufel MD James E. Mitchell MD Ross D. Crosby PhD Claudia Prestano PhD Dana A. Satir PhD Susan Simpson DClinPsych Richard Sly PhD J. Hubert Lacey MD Colleen Stiles‐Shields Giorgio A. Tasca PhD Glenn Waller DPhil Shannon L. Zaitsoff PhD Renee Rienecke PhD Daniel Le Grange PhD Jennifer J. Thomas PhD 《The International journal of eating disorders》2017,50(4):323-340
The therapeutic alliance has demonstrated an association with favorable psychotherapeutic outcomes in the treatment of eating disorders (EDs). However, questions remain about the inter‐relationships between early alliance, early symptom improvement, and treatment outcome. We conducted a meta‐analysis on the relations among these constructs, and possible moderators of these relations, in psychosocial treatments for EDs. Twenty studies met inclusion criteria and supplied sufficient supplementary data. Results revealed small‐to‐moderate effect sizes, βs = 0.13 to 0.22 (p < .05), indicating that early symptom improvement was related to subsequent alliance quality and that alliance ratings also were related to subsequent symptom reduction. The relationship between early alliance and treatment outcome was partially accounted for by early symptom improvement. With regard to moderators, early alliance showed weaker associations with outcome in therapies with a strong behavioral component relative to nonbehavioral therapies. However, alliance showed stronger relations to outcome for younger (vs. older) patients, over and above the variance shared with early symptom improvement. In sum, early symptom reduction enhances therapeutic alliance and treatment outcome in EDs, but early alliance may require specific attention for younger patients and for those receiving nonbehaviorally oriented treatments. 相似文献