Effects of Hantaan virus on cytoskeletons of human endothelial cells

ＥｆｆｅｃｔｓｏｆＨａｎｔａａｎｖｉｒｕｓｏｎｃｙｔｏｓｋｅｌｅｔｏｎｓｏｆｈｕｍａｎｅｎｄｏｔｈｅｌｉａｌｃｅｌｌｓＺｈｕｐｉｎｇ（朱平）；ＬｉｕＪｕｎｂｉｎ（刘俊彬）；Ｙａｎｒｏｎｇ（阎荣）；ＫａｎｇＷｅｎｚｈｅｎ（康文臻）；ＷｕＨｏｎｇ（吴红）...     

Histopathological and immunohistochemical studies of 120 cases of osteosarcoma

Ｈｉｓｔｏｐａｔｈｏｌｏｇｉｃａｌａｎｄｉｍｍｕｎｏｈｉｓｔｏｃｈｅｍｉｃａｌｓｔｕｄｉｅｓｏｆ１２０ｃａｓｅｓｏｆｏｓｔｅｏｓａｒｃｏｍａＧａｏＦｅｎｇｘｕｎ（高奉浔）；ＬｉＺｅｎｇｐｅｎｇ（李增鹏）；ＤｏｎｇＺｈｉｑｉａｎ（董志谦）；ＳｕＨｏｎｇ...     

The assessment of the outliers of logistic regression model and its clinical application

ＴｈｅａｓｓｅｓｓｍｅｎｔｏｆｔｈｅｏｕｔｌｉｅｒｓｏｆｌｏｇｉｓｔｉｃｒｅｇｒｅｓｓｉｏｎｍｏｄｅｌａｎｄｉｔｓｃｌｉｎｉｃａｌａｐｐｌｉｃａｔｉｏｎＹｉＤｏｎｇ（易东）；ＸｕＲｕｆｕ（许汝福）；ＺｈａｎｇＷｅｉ（张蔚）；ＹｉｎＱｕａｎｈｕａｎ（尹...     

Screening of controls in cass-control study of infectious diseases

Ｓｃｒｅｅｎｉｎｇｏｆｃｏｎｔｒｏｌｓｉｎｃａｓｓ－ｃｏｎｔｒｏｌｓｔｕｄｙｏｆｉｎｆｅｃｔｉｏｕｓｄｉｓｅａｓｅｓＬｉＬｉａｎｇｓｈｏｕ（李良寿）；ＸｕＤｅｚｈｏｎｇ（徐德忠）；ＹａｎＹｏｎｇｐｉｎｇ（阎永平）（ＤｅｐａｒｔｍｅｎｔｏｆＥｐｉｄｅｍ...     

Binding mechanism of interface of porous coated titanium alloy prostheses

ＢｉｎｄｉｎｇｍｅｃｈａｎｉｓｍｏｆｉｎｔｅｒｆａｃｅｏｆｐｏｒｏｕｓｃｏａｔｅｄｔｉｔａｎｉｕｍａｌｌｏｙｐｒｏｓｔｈｅｓｅｓＺｏｕＨｏｎｇｅｎ（邹宏思）；ＹｅＪｕｎ（叶军）；ＴａｎｇＮｏｎｇｘｕａｎ（唐农轩）；ＹｕａｎＣｕｎｈｕａ（袁存华）（Ｄｅ...     

Inhibiting effects of verapamil on respiratory burst of polymorphonuclear leucocytes

ＩｎｈｉｂｉｔｉｎｇｅｆｆｅｃｔｓｏｆｖｅｒａｐａｍｉｌｏｎｒｅｓｐｉｒａｔｏｒｙｂｕｒｓｔｏｆｐｏｌｙｍｏｒｐｈｏｎｕｃｌｅａｒｌｅｕｃｏｃｙｔｅｓＬｉｕＸｕｅｆｅｎ（刘雪芬）；ＣｈｅｎＳｈｕｙｕａｎ（陈树元）；ＬｉａｏＸｉｌｉｎｇ（廖锡麟）（Ｄｅ...     

Effects of inhibition of glycolysis on calcium homeostasis and functional recovery of stunned myocardium

ＥｆｆｅｃｔｓｏｆｉｎｈｉｂｉｔｉｏｎｏｆｇｌｙｃｏｌｙｓｉｓｏｎｃａｌｃｉｕｍｈｏｍｅｏｓｔａｓｉｓａｎｄｆｕｎｃｔｉｏｎａｌｒｅｃｏｖｅｒｙｏｆｓｔｕｎｎｅｄｍｙｏｃａｒｄｉｕｍＧｕｏＷｅｎｙｉ（郭文怡）；ＯｕＪｉｎｘｉ（区晋禧）；ＪｉａＧｕｏｌ...     

A study of point mutation of ras genes in human gastric cancer

Ａｓｔｕｄｙｏｆｐｏｉｎｔｍｕｔａｔｉｏｎｏｆｒａｓｇｅｎｅｓｉｎｈｕｍａｎｇａｓｔｒｉｃｃａｎｃｅｒ￥ＷａｎｇＪｕｎｒｕ（王俊茹）；ＬｉｕＷｅｉｗｅｎ（刘为纹）；ＤｅｎｇＧｕｏｒｅｎ（邓国仁）；ＬｕＹｏｕｙｏｎｇ（吕有勇）；ＷａｎｇＸｉｎ（王欣）（...     

Clinical Study of Blastocyisasis in Children of Fuzhou District

ＣｌｉｎｉｃａｌＳｔｕｄｙｏｆＢｌａｓｔｏｃｙｉｓａｓｉｓｉｎＣｈｉｌｄｒｅｎｏｆＦｕｚｈｏｕＤｉｓｔｒｉｃｔＷｕＢｉｎ（吴斌）；ＺｈａｏＺｉｑｉｎｇ（赵子庆）；ＨｕａｎｇＭｉａｏｈｕｉ（黄妙辉）ａｎｄＳｕＱｉｎｇｐｉｎｇ（苏庆平）（ＴｈｅｌｓｔＡｆ...     

A Study of Phagocytosis and Intracellular Killing of Human Colostral Phagocytes

ＡＳｔｕｄｙｏｆＰｈａｇｏｃｙｔｏｓｉｓａｎｄＩｎｔｒａｃｅｌｌｕｌａｒＫｉｌｌｉｎｇｏｆＨｕｍａｎＣｏｌｏｓｔｒａｌＰｈａｇｏｃｙｔｅｓＹｉｎＳｈｕｄｏｎｇ（殷曙东）；ＱｉａｎＱｉｎｇ（钱倩）；ＣｈｅｎＲｏｎｇｈｕａ（陈荣华）（Ｄｅｐａｒｔｍｅｎｔ...     

急性牵拉对兔正中神经内血循环的影响

通过已建立了的家兔在体正中神经瞬时应力和应变定量的单纯性牵拉伤动物模型，对定量张力与神经内血循环变化的关系进行了研究。结果表明：神经承受急性牵拉时，最先影响的是神经内静脉回流；随着牵拉的继续，有效循环血量明显减少，血管通透性增加，蛋白质外渗；进一步牵拉，则发生神经内供血中断。文中还讨论了周围神经牵拉伤的主要致伤因素和神经内血循环变化的临床意义。     

胫神经肌支转位治疗高位腓总神经损伤的解剖学研究

目的 对近端胫神经的肌支情况进行解剖学测量,探讨胫神经肌支转位治疗腓总神经高位损伤或长段损伤的手术可行性.方法 选取12具(23侧)中性甲醛固定的成人下肢标本,解剖并测量胫神经近端各肌支的长度、入肌点处的直径、分支点至腓骨小头平面的距离(位置)及至腓骨颈的距离;从分叉部向近端膜内分离腓总神经的腓深、腓浅两部分,测量腓总神经可分离的最大长度以及腓深神经的直径.将腓深神经于分离的最高点处切断并模拟移位,观察胫神经肌支与腓深神经无张力缝合的可行性.结果 胫神经近端主要肌支有比目鱼肌支、腓肠肌外侧头支和腓肠肌内侧头支,其长度分别为(53.2±9.9)、(36.3±9.6)和(44.7±8.6) mm;从分叉部向近端膜内分离腓总神经的最大长度为(59.3±7.2) mm;分离后,所有标本的比目鱼肌支和腓肠肌外侧头支以及21侧(91.3％)标本的腓肠肌内侧头支均可直接与腓深神经无张力地吻合.结论 膜内分离腓总神经后,胫神经肌支转位治疗腓总神经长段损伤或高位损伤在解剖学上可行.综合考虑各肌支的长度和直径,比目鱼肌支是移位的最佳供体神经.     

皮神经营养血管蒂岛状皮瓣的动物实验研究

目的：建立皮神经营养血管蒂岛状皮瓣动物实验模型，探讨蒂部不同结构对皮瓣血供的影响。方法：各取新西兰大白兔5只，分别进行活体及灌注解剖确定皮瓣模型，另采用24只根据不同蒂部组织切断类型分为4组，每组6只12测，1组为皮神经营养血管皮瓣组；2组为皮神经内血管供养组；3组为皮神经外血管供养组；4组为对照组。结果：兔股内侧皮神经及营养血管起源于股神经及股动静脉，走行于大腿内侧中段，沿途发出3--6个皮支供养大腿后内侧区皮肤。分组实验皮瓣成活情况以1组最佳，2、3组次之，4组最差。结论：兔股内侧皮神经营养血管皮辫是一种可靠的动物实验模型，其血供由皮神经内血管及皮神经外血管丛共同提供，且后者更重要。     

Tarsal tunnel surgery for treatment of tarsal ganglion: a rewarding operation with devastating potential complications

Three patients who originally presented with a mass in the tarsal tunnel are described to develop an algorithm for management of the tarsal ganglion. All three patients had complications from ganglion excision, including complete division of the posterior tibial nerve, injury to the posterior tibial artery, and ganglion recurrence. The guiding principles relating to the presence of an extraneural versus an intraneural ganglion are developed. An example of a posterior tibial intraneural ganglion is presented.     

Lipofibromatous hamartoma of the median nerve with long-term follow-up

Lipofibromatous hamartoma is a rare, benign tumor that most often involves the median nerve. A 16-year-old male with lipofibromatous hamartoma of the median nerve at the wrist level is described. This patient was a child when the mass was first noted. Although there were no symptoms or signs of carpal tunnel compression, the growth of the tumor was progressing. In addition to the release of the carpal tunnel, microsurgical intraneural dissection was done to preserve the thenar motor branch. Then segmental excision of the residual sensory component with sural nerve grafting was performed. Subjectively the patient did not notice the minor motor deficit, however, the patient did experience numbness of fingertips after surgery. There were no scars or trophic ulcers on fingertips at 3 years of follow-up regardless of the inadequate sensory return. Treatment of this benign tumor is still controversial. The relevant reports in the literature are reviewed.     

电刺激在修复远端尺神经损伤中的应用

目的 :阐明神经束支定位法在远端尺神经损伤修复中的作用。方法 :选择 4 2例远端尺神经损伤病例 ,进行神经内束支分离 ,双极电刺激定位后束膜吻合 ,与 17例外膜吻合组对照。结果 :束支分离定位法在远端尺神经损伤修复中的成功率为 90 .5%,治疗组较对照组感觉恢复率有提高 ,但无明显差异 ( P>0 .0 5) ,运动功能恢复率显著提高 ( P<0 .0 1)。结论 :神经内束支分离定位应用于远端尺神经损伤修复是可行的 ,并能提高其功能恢复率。     

右侧第三颅神经原发神经内神经束膜瘤1例及文献复习

目的报道1例罕见的右侧第三颅神经发生的神经束膜瘤,探讨其组织病理学特点和鉴别诊断,提高对该病的认识。方法右侧第三颅神经发生的肿瘤行部分切除,一部分瘤组织用多聚甲醛固定用作常规苏木精-伊红染色和免疫组织化学染色;另一部分用戊二醛固定用作电子显微镜观察。结果瘤细胞排列成典型的"洋葱头"样构象,免疫组织化学染色显示上皮膜抗原(EMA)和CD34阳性;电镜观察显示瘤细胞具有细长的胞质突起并呈现同心圆状的排列。结论神经束膜瘤是一种罕见的良性肿瘤,常发生于外周神经;颅神经原发的神经束膜瘤极为罕见。该例是已知报道中第2例发生于第三颅神经的病例。该肿瘤应当和中枢神经系统发生的神经鞘瘤、神经纤维瘤、孤立性纤维性肿瘤(SFT)、低分化纤维黏液肉瘤(LGFS)和脑膜瘤进行鉴别。     

关节松动术联合肌肉牵伸在脑卒中后偏瘫肩痛患者中的应用效果

目的 探讨关节松动术联合肌肉牵伸对脑卒中后偏瘫肩痛(HSP)患者血清炎性因子及血液流变学的影响。方法 采用随机数字表法将120例脑卒中后HSP患者随机分为试验组和对照组,每组60例。对照组采用肩胛带控制训练、神经松动技术、经皮神经电刺激等常规康复治疗,试验组在对照组的基础上采用关节松动术联合肌肉牵伸技术治疗。治疗4周后,比较两组视觉模拟疼痛评分(VAS)、上肢运动功能(FMA-UE)、日常生活能力(MBI)、炎性因子[超敏C-反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]、血液流变学[全血高切、中切、低切黏度]。结果 试验组VAS评分低于对照组,FMA-UE、MBI高于对照组(P<0.05)。血清hs-CRP、IL-6、TNF-α低于对照组(P<0.05)。试验组全血高切、中切、低切黏度低于对照组(P<0.05)。结论 关节松动术联合肌肉牵伸能缓解HSP,促进上肢功能及日常生活能力的恢复,可能与拮抗炎症反应、血液流变等因素有关。     

青光眼眼部彩色多普勒血流显像分析

利用彩色多普勒血流显像对比分析了２０例正常人（４０只眼），２３例青光眼（３２只眼）的眼部超声结构参数和彩色多普勒血流显像参数，发现前房变浅，晶状体增厚，视神经变窄及视网膜中央动脉阻力指数升高，视网膜中央动、静脉血流量减少及睫状动脉血流速度增高和血流量增加是诊断青光眼的重要指标，尤其对低眼压性青光眼有重要的临床意义。     

The role of vague nerve in the hemodynamic changes induced by acute biliary tract pressure increase

Summary In order to explore the mechanism of hemodynamic changes caused by high biliary tract pressure, we established an animal model of high biliary tract pressure, in which the disturbance of hemodynamics developed. The cervical or abdominal vague nerve was then blocked. It was observed that when the biliary tract pressure was increased to 16 kPa and kept for 1 h, the arterial blood pressure and cardiac output decreased immediately and parallelly (P<0.05). When the cervical or abdominal vague nerve were blocked or the pressure of the biliary tract was decreased to zero, both indices returned to normal immediately (P> 0. 05). The change of cardiac output lags a little behind that of arterial blood pressure. It suggests that the signal of biliary tract pressure increase can be sent to the cardiovascular center through vague nerve, and the balance between sympathic and parasympathic nerve was broken, which led to the weakening of cardiac contraction and decrease of cardiac output. Due to the peripheral effects of vague nerve, hemodynamic resistance of vessels decreased, which brought about redistribution of peripheral blood flow. Both were the causes of hemodynamic disturbances. After the blood pressure decreased markedly, it showed a jump to normal state when cervical vague nerve was blocked. And the amplitude of diastolic blood pressure restored more than that of systolic blood pressure. This suggests that the cardiac output and peripheral blood resistance are important factors that cause the decrease of blood pressure.