中西医结合治疗慢性盆腔炎60例

目的研究慢性盆腔炎患者实施中西医结合治疗的临床效果,分析其临床价值。方法选择我院2013年1月～4月共收治的60例慢性盆腔炎患者,随机分成实验组和对照组,每组30例。对照组给予单纯的西医治疗,实验组于对照组的基础上增加中药治疗,然后分析两组的临床效果。结果通过治疗后,实验组患者的临床效果相对于对照组的临床效果更佳,总有效率为96.7%。结论慢性盆腔炎患者实施中西医结合治疗具有良好的临床疗效,值得临床推广。     

中药灌肠治疗慢性盆腔炎129例护理体会探究

目的：探索用中药灌肠方法治疗慢性盆腔炎在护理中采取的方法。方法选取2013年6月~2014年6月治疗的258例患者,随机均分为实验组和对照组,对对照组采取常规护理方法,实验组在此基础上给以心理护理、中药灌肠两种护理方式。经过3个疗程的治疗,所有129例患者,有61例痊愈,60例显效,4例有效,4例无效,有效率高达93.8%。结果对大多数患者有显著效果,该方法得到的结果有统计学意义。结论使用中药灌肠法治疗慢性盆腔炎,有较好的疗效,临床推广意义较大。     

利用前列腺注射标本经直肠穿刺注射药物治疗慢性前列腺20例疗效观察

1997年以来我院附属医院医生和实验室老师利用在标本上反复操作训练采用经直肠穿刺注射药物治疗慢性前列腺20例，取得良好效果，现报告如下：     

基层医院运用多巴胺与速尿腹腔内注射治疗腹水的临床观察

本院属基层医院,2008年10月前未将内科细化,混合收住各型腹水病人。2005年8月～2008年10月我们除常规治疗外,采用多巴胺与速尿联合腹腔内注射治疗腹水,取得满意疗效,现报告如下：     

丁脲胺与多巴胺腹腔内注射联合白蛋白静滴治疗肝硬化难治性腹水24例疗效观察

腹水、低蛋白血症是肝硬化常见并发症。血管活性药物多巴胺加呋塞米腹腔内注射治疗肝硬化腹水报道较多。而利尿作用更强、副反应较小的丁脲胺腹腔内注射很少见相关报道,尤其联合静滴白蛋白未见相关报道（可能与价昂有关）。2006～2009年,我科应用丁脲胺腹腔内注射治疗肝硬化腹水24例,取得良好效果,现报道如下。     

整体护理模式应用于盆腔治疗仪治疗慢性盆腔炎中的效果观察

目的：探究在盆腔治疗仪治疗盆腔炎过程中应用整体护理模式的临床效果。方法选取2011年~2013年来我院就诊的慢性盆腔炎患者200例,将其随机分成研究组100例和对照组100例,研究组患者给予整体护理措施,对照组只做常规护理工作,观察比较两组有效率的差别。结果研究组患者总有效率为93.0%,而对照组仅为83.0%,两组间比较具有显著的统计学意义(<0.05)。结论在使用盆腔治疗仪治疗盆腔炎的同时,要进行心理、饮食、生理、生活等各方面的整体护理措施,能够明显提高慢性盆腔炎的治疗效果。     

79例卵母细胞浆内单精子注射术(ICSI)治疗男性不育临床及安全性研究

目的对比分析应用卵母细胞浆内单精子注射(ICSI)技术和常规的体外受精与胚胎移植(IVF-ET)技术治疗不育的临床资料,为卵母细胞浆内单精子注射技术的临床应用提供安全性依据。方法回顾性分析79例接受技术治疗不育的资料,并与同期288例接受常规的体外受精与胚胎移植(IVF-ET)技术的病例对比分析。结果在受精率及流产率方面,ICSI组均低于IVF-ET组,卵裂率、妊娠率及胚胎形态方面,围生期结果两组比较无显著性差异(P>0.05)。结论ICSI治疗男性严重少弱精子症的效果是肯定的,出生后代安全性与IVF-ET相似。但ICSI出生后代安全性的确定仍需大样本研究及长期随访。     

羟基喜树碱腹腔注射治疗消化道肿瘤的临床观察及护理

消化道肿瘤是我国最常见的癌症之一,晚期的消化道肿瘤扩散转移腹腔在临床较为常见且愈后极差中位生存期久3～6月左右而全身化疗由于药物很难穿透腹腔有效率仅10%～15%.这部分病人因体质差,且晚期患者的生活状态评分较低不能耐受强烈的药物化疗.所以选择无交叉耐药性对消化道肿瘤有一定疗效.毒性低的抗癌药就显得更加重要.2000年5月～2007年5月我科使用羟基喜树碱腹腔注射治疗40例消化道肿瘤具有较好的效果.现报告如下:     

甘乐能治疗慢性肝炎25例临床观察与护理

甘乐能为商品名称,其通用名称为重组人干扰素a-2b注射液.我科自2005年起应用甘乐能治疗慢性乙型肝炎,慢性丙型肝炎等,取得较好疗效.现将护理体会报告如下:     

知柏地黄丸联合洁刮术治疗阴虚火旺型慢性牙周炎患者60例疗效观察

目的：探讨知柏地黄丸联合洁刮术治疗阴虚火旺型慢性牙周炎的疗效。方法将120例阴虚火旺型慢性牙周炎患者采用随机数字表法分为对照组(n=60)和观察组(n=60),两组均给予洁刮术治疗,观察组联合应用知柏地黄丸,连续服用12w后比较分析两组的疗效及牙齿菌斑指数(PLI)、探诊深度(PD)、附着丧失(AL)和牙龈出血指数(BI)。结果观察组的总体有效率为95.00%,明显高于对照组的83.33%(P<0.05)。两组治疗后的PLI、PD、AL及BI均明显低于治疗前(P<0.05);观察组治疗后的PD和AL明显低于对照组(P<0.05)。结论知柏地黄丸联合洁刮术治疗阴虚火旺型慢性牙周炎的疗效优于单纯洁刮术治疗,因此该联合治疗方案值得临床推广应用。     

Clinical aspects of pelvic inflammatory disease

Pelvic inflammatory disease (PID) is a common and poorly managed condition. Untreated or inadequately treated, it leads to tubal infertility, ectopic pregnancy and chronic pelvic pain. Diagnostic difficulties are compounded by the wide variety of clinical presentations and the insensitivity and poor specificity of laboratory tests. Better recognition of mild and atypical disease needs a high index of suspicion whenever young, sexually active women present with gynaecological symptoms. Laparoscopy supplemented by microbiological tests and fimbrial minibiopsy should be regarded as the diagnostic 'gold standard' for research studies; new studies are required to identify techniques which might reduce under- and over-diagnosis. Early treatment reduces the risk of an adverse effect on fertility. Any therapeutic regimen selected should be effective against the common aetiological agents Chlamydia trachomatis, Neisseria gonorrhoeae, genital mycoplasmas and aerobic and anaerobic bacteria. Since at least 60% of cases of PID can be attributed to infection with a sexually transmitted organism, partner notification forms an essential part of management.      

Xanthogranulomatous salpingitis as a rare pathologic aspect of chronic active pelvic inflammatory disease

Xanthogranulomatous salpingitis (XGS) is a rare form of chronic inflammation of the fallopian tubes. A 41-year old woman with a history of secondary infertility for 2 years is presented. The patient underwent bilateral salpingooopherectomy with presumptive diagnosis of adnexal mass with cystic component. Intraoperative pathology consultation was done. The diagnosis of bilateral XGS associated with chronic active follicular salpingitis was made. XGS is reported to be caused by an unsuccesfully treated pelvic inflammatory disease. Its association with chronic active follicular salpingitis has not been previously reported. Chronic active follicular salpingitis with xanthogranulomatous inflammation might give the impression of a cystic adnexal mass with septations on preoperative pelvic computed tomography. Frozen sections are necessary to rule out malignancy as done in our case.     

A school nursing approach to childhood obesity: an early chronic inflammatory disease

Background and aim: Childhood obesity is widespread in all industrialized European countries and it contributes significantly to population morbidity and mortality.

Moreover, obesity is a chronic disease with a multifactorial etiology including genetics, environment, metabolism, lifestyle and behavioral components. This article addresses the school nursing approach thought: education of children and their families, participation in policy-making process to improve nutrition and activities for children.

Conclusions: The future policies surrounding pediatric obesity must include continued focus on prevention and treatment. Forming broad partnerships that include the government, communities, professional organizations, industries, schools, preschools, day care, and family will improve the likelihood for successful implementation.     

慢性盆腔炎动物模型子宫病理学改变与血流变学关系

目的 探讨慢性盆腔炎(chronic pelvic inflammatory disease,CPID)动物模型子宫病理学改变与其血液流变学之间的关系.方法 用混合菌接种法诱导大鼠CPID动物模型,其中假手术组仅打开腹腔,不注射混合菌,光镜下观察大鼠子宫的病理改变,并以锥板法检测血液流变学各项指标.结果 CPID大鼠模型病理学显示慢性炎症改变,血液流变学各项指标显著升高(P<0.01).结论 CPID动物模型子宫病理学改变与血流变学各项指标的升高关系密切.     

Role of anaerobes in acute pelvic inflammatory disease

Pouch of Douglas aspirates were collected from 50 women with history and examination suggestive of acute pelvic inflammatory disease (PID) and 20 healthy women admitted for tubal ligation served as control. A total of 57 microorganisms were isolated from 37 patients out of 50 in study group. Of 37 positive cultures 21(56.7%) were monomicrobial and 16(43.2%) were polymicrobial. Most common symptom in study group was lower abdominal pain (90%), vaginal discharge (70%) and irregular bleeding (40%) and 30% patients had history of intrauterine contraceptive device (IUCD) implantation. The predominant aerobic isolates were Escherichia coli, Coagulase Negative Staphylococcus (CONS), Staphylococcus aureus, Klebsiella pneumoniae while common anaerobes were Bacteroides fragilis, Prevotella melaninogenica, Fusobacterium nucleatum and Peptostreptococcus spp. Our study shows that cefotaxime, cefuroxime and gentamicin may be used for gram negative aerobic bacilli; cloxacillin, cephaloridine and erythromycin for aerobic gram positive cocci and amikacin and ceftazidime for Pseudomonas aeruginosa. Thus for optimum therapy of acute PID it is beneficial to keep in mind major conceptual changes and therapeutic realities that have influenced current understanding of acute PID and have affected the choice of therapy.     

Vaginal douching as a possible risk factor for pelvic inflammatory disease

To prevent pelvic inflammatory disease (PID) and its consequences, risk factors must be identified. A review of the literature supports the possibility that vaginal douching may affect the risk factor of PID, and new data are presented on douching practices of women hospitalized with PID. Individual case reports and controlled studies support associations between vaginal douching and both PID and ectopic pregnancy. The prevalence and distribution of douching are also compatible with a possible association. The temporal pattern of PID symptoms may be linked to douching and menses. The nature of the douche solution and the douching technique may be important variables with regard to douching as a PID risk factor. A case-control epidemiologic study is recommended to clarify the relationships between PID and douching.     

Persistence of chlamydial antibodies after pelvic inflammatory disease.

The persistence of chlamydial immunoglobulin G (IgG) antibodies and long-term sequelae of pelvic inflammatory disease (PID) were studied in 70 women who had been treated for PID 3 to 6 years previously. Fifty-one women had had PID associated with Chlamydia trachomatis infection (Chlamydia group), and 19 women had had PID not associated with C. trachomatis (non-Chlamydia group). Chlamydial IgG antibodies, as determined by the indirect immunofluorescence test with inclusions of C. trachomatis L2 as antigens, persisted at stable levels in 43% of the women for up to 6 years; 43% of the women showed a decrease in IgG titer, and 13% showed an increase. IgA antibody levels in serum correlated with IgG antibody levels in serum and with the presence of cervical IgA antibodies. Both serum antibodies and cervical IgA antibodies were more often found in the Chlamydia group. Forty-two percent of the women were infertile. Every fifth subsequent pregnancy was ectopic. The presence of cervical IgA antibodies might protect the women from tubal damage.     

Sickle cell disease: a chronic inflammatory condition.

Homozygous sickle cell disease (SCD) has a wide spectrum of clinical manifestations which varies from an almost asymptomatic condition to severe illness, despite the fact that all subjects with this disease have the same base change in their DNA. The source of this variation is partly environmental, but a large part of this variability can derive from the presence of genetic modulators which are not fully understood. It was postulated that some degree of immunodeficiency should be associated with this condition, but no deficiency, directly related to a given component of the immune system, was observed that could explain the high levels of recurrent infections presented by sickle cell disease patients. Reviewing data from the literature we suggest that the influence of the immune system in the variation of clinical manifestations presented by SCD patients is not related with any immunodeficiency but is rather the result of a chronic inflammatory condition.