LAK细胞对眼部恶性肿瘤的免疫治疗临床观察

本文应用 rIL-2体外诱导自身 LAK(Lynphokine-Activated Killing)细胞,对眼部恶性肿瘤病人进行瘤区局部治疗,取得较好的疗效,16例恶性肿瘤中,基底细胞癌5例;完全消退4例,部分消退1例,睑板腺癌4例,鳞状细胞癌2例,视网膜母细胞瘤,眶内非何杰金氏淋巴瘤,眶内血管外皮瘤,眶内纤维组织细胞瘤(生长活跃),汗腺癌各1例,都获完全消退.以上结果表明,病人自身 LAK 细胞局部治疗是一种有效的免疫方法.眼科学报 1993;9:51-54。     

IOP LOWERING EFFICACY OF BIMATO-PROST IN GLAUCOMA AND OCULAR HY-PERTENSION PATIENTS NON-RESPONSIVE TO LATANOPROST

Purpose: To determine if bimatoprost is effective in patients who are non-responsive to latanoprost Methods: Open-label, single site monocular trial conducted in two phases. After completing a washout of any ocular hypotensive agents, patients with IOP between 22 and 34 mmHg (n=51) instilled latanoprost in one eye and were evaluated at weeks 4 and 8 (Phase 1). Patients with an     

INTRAOCULAR PRESSURE (IOP) VARIA-TIONS IN DIFFERENT POSITIONS IN PA-TIENTS WITH GLAUCOMA ASSOCIATED WITH EXFOLIATION SYNDROME (GXFS)

Purpose: To analyze the IOP in different positions in exfoliation syndrome glaucoma (GXFS) and to compare them with primary open-angle glaucoma (POAG) patients and normal subjects without glaucoma (normals). Methods: 3 groups of 10 patients each were evaluated. IOP was measured in a seating position,     

SHORT-TERM EFFECT OF LATANOPOST ON INTRAOCULAR PRESSURE AND OCU-LAR CIRCULATION IN OCULAR HYPER-TENSION

Purpose: To determine the stort-term effects of latano-prost (Xalatan) on the retrobulbar circulation and intraocular pressure (IOP) in ocular hypertension. Materials and Methods: Forty-six eyes of 23 consecutive ocular hypertension patients older than 20 years. All patients had IOP greater than 22 mmHg. One eye of each patient was randomly selected to take     

EVALUATION OF CIRCADIAN INTRAOCU-LAR PRESSURE IN PATIENTS WITH GLAUCOMA OR OCULAR HYPERTEN-SION: THE BEHAVIOUR OF DIFFERENT ANTIGLAUCOMATOUS DRUGS

Purpose: In 3 cross-over clinical trials we compared around-the-clock intraocular pressure (IOP) reduction induced by timolol, latanoprost, dorzolamide, brimonidine, a fixed combination of timolol and dorzolamide, bimatoprost and travoprost in patients with open-angle glaucoma or ocular hypertension. Methods: Each trial included 20 patients who were all treated     

NEOVASCULAR GLAUCOMA ASSOCIATED WITH OCULAR HYPOPERFUSION SECONDARY TO CAROTID ARTERY DISEASE

Three cases of neovascular glaucoma associated with ocular hypoperfusion secondary to carotid artery disease are reported. In two cases, anastomosis of the internal and external carotid artery systems via a superficial temporal artery to the middle cerebral artery (Yasargil procedure) resulted in resolution of the rubeosis, relief of the ocular pain and improvement of the circulation of the globe. The third case, which did not have this procedure, resulted in a blind eye with severe rubeotic glaucoma.     

SCANNING LASER POLARIMETRIC FOL－LOW－UP OF TURKISH PATIENTS WITH OCULAR HYPERTENSION

Purpose: To detect the progression of glaucomatous damage in the retinal nerve fiber layer (RNFL) in ocular hypertensive (OHT) patients with scanning laser polarimetry. Materials and methods: 15 females, 5 males whose ages range between 36 and 75 years (mean age: 54.15 ±12.11 years) were included in the OHT study group. Patients with intraocular pressure (IOP)