共查询到20条相似文献,搜索用时 62 毫秒
1.
口服特比萘芬联合外用治疗32例头癣 总被引:3,自引:0,他引:3
特比萘芬[Terbinafine,商品名疗霉舒(Lamisil)]由瑞士诺华公司(原名山德士药厂)生产,为丙烯胺类抗真菌药物,已被广泛应用于临床治疗体股癣、手足癣和甲癣等真菌感染,疗效显著,安全可靠。我们于1995年7月使用口服疗霉舒结合外用治疗32... 相似文献
2.
3.
特比萘芬片口服联合特比萘芬凝胶外用治疗足癣疗效观察 总被引:2,自引:0,他引:2
程子兴 《中国医学文摘:皮肤科学》2010,27(2):84-85
目的探讨口服特比萘芬联合外用特比萘芬凝胶治疗足癣的疗效。方法将足癣患者124例随机分成两组,治疗组64例,口服特比萘芬1次/d,同时外用1%特比萘芬凝胶2次/d,疗程2周。对照组60例,局部外用1%特比萘芬凝胶2次/d,疗程4周。结果治疗组治愈率为96.9%,真菌清除率为90.6%;对照组分别为91.7%和86.7%。结论联合疗法和单一外用药物治疗足癣均有效,但联合疗法起效快、效果较好。 相似文献
4.
5.
头癣好发于儿童,是由真菌感染头皮毛发所致。以往常口服灰黄霉素或酮康唑治疗,虽然具有一定的疗效,但治疗时间较长,且具有较明显的副作用,不易为患儿家长所接受。我们于1996年4月-1997年8月采用瑞士山德士药厂生产的特比萘芬片剂及其1%霜剂治疗头癣10... 相似文献
6.
近年来头癣的发病率有所增加 ,我们用齐鲁制药厂研制的特比萘芬治疗儿童头癣 ,取得满意效果 ,现将 13例总结如下。一般资料 13例头癣病人中男 8例 ,女 5例 ;年龄 5~ 14岁 ;病程 2 0天~ 1年 ,白癣 12例 ,脓癣 1例 ,损害呈蚕豆大至拳头大 ,数目 1~ 14个。 13例头癣病人经流行病学调查 ,家中饲养猫、狗等小动物 9例 ,2例家中虽未饲养 ,但经常到邻居家玩耍猫、狗。 13例病人 ,农村 9例 ,城市 4例。所有病例真菌直接镜检均阳性 ;真菌培养鉴定为犬小孢子菌 12株 ,紫色毛癣菌 1株。治疗方法 体重 <18.5kg的病儿每日特比萘芬 [山东齐鲁制药… 相似文献
7.
笔者于2000年10月—2003年12月,采用特比萘芬片和1%特比萘芬软膏(丁克软膏)治疗体、股癣患者,观察两药的疗效,现报告如下。 相似文献
8.
我们从 1999年 3月~ 2 0 0 0年 1月应用山东齐鲁制药厂生产的特比萘芬治疗 36例甲癣病人 ,取得满意效果 ,现报告如下。临床资料 36例均为门诊病人 ,其中男 15例 ,女 2 1例 ;病程 3月~ 15年 ;36例患者中共有病指甲 82个 ,病趾甲 195个 ;其中合并手癣、足癣或股癣的病人共 2 0例 ,全部病例治疗前直接镜检均阳性 ,且 2周内未曾内服或外用过其它抗真菌药。治疗方法 特比萘芬第 1周每日 1次 ,每次 2 5 0mg ;自第 2周开始 ,隔日 1次 ,每次 2 5 0mg,指甲癣共服 7周 ,趾甲癣共服 11周 ,服完全部药物 4周后观察治疗结果。疗效判断标准 痊愈… 相似文献
9.
特比萘芬的临床应用研究进展 总被引:2,自引:0,他引:2
特比萘芬是一种有效的抗真菌药物 ,对于头癣、手足癣、体股癣、甲真菌病等浅部真菌病具有较好的疗效 ,并且耐受良好 ,不良反应轻 ,最常见的不良反应是胃肠道反应和皮疹 ,然而在临床应用过程中仍须注意其可能发生的少见的严重不良反应 ,如超敏反应综合征和急性肝坏死。关于特比萘芬在深部真菌病的应用 ,临床资料十分有限 ,仍需进一步积累经验 相似文献
10.
笔者于2001年8月~2004年2月对75例甲真菌病患者采用特比萘芬(山东齐鲁制药厂生产)进行治疗,获得满意疗效,现报告如下: 相似文献
11.
12.
13.
Usefulness of TrichoScan professional in the evaluation of hair loss in females. Report of 180 cases
V. López J.M. Martín R. Sánchez C. Ortega J.M. Ricart 《Journal of the European Academy of Dermatology and Venereology》2011,25(9):1068-1072
Background TrichoScan Professional is a computerized program used for digital measurement of hair growth and hair loss. The aim of our study was to undertake an evaluation with TrichoScan Professional of female patients consulting at our hospitals for hair loss. The purpose of our study was to determine whether TrichoScan was able to identify differences in hair parameters that would correlate with the pattern of alopecia or according to the age of the patients evaluated. Material and methods One hundred‐eighty women that consulted consecutively for loss of hair were included. Patients were aged between 8 and 85 years (mean age 36 years). Data including age, the number of hairs, hair density per square centimetre, anagen and telogen percentage and percentage of terminal and miniaturized hair were analysed. Results Results observed with TrichoScan were as below: number of hairs (mean 154.9; range 34–316). Hair density per square centimetre (mean 239; range 52–486). Hair in anagen phase (mean 62.4%; range 9–93%). Hair in telogen phase (mean 37.4%; range 7–91%). Terminal hair (mean 95.2%; range 82–100%). Vellus hair (mean 4.7%; range 0–17%). Pearson′s correlation test was used to measure the strength of the association of age with the rest of parameters. The statistical analysis showed a significant correlation between age and both the number of hairs and the hair density per square centimetre. However, no significant correlation between age and rest of the parameters was observed. Conclusions TrichoScan Professional may help to quantify hair density and in our sample, this was the only parameter showing a significant decrease according to age in various types of alopecia affecting the females. 相似文献
14.
15.
16.
17.
18.
19.
We describe a 63-year-old man who presented with painful malodorous lesions in the perianal, perineal and scrotal regions. Following definitive diagnosis of paracoccidioidomycosis, he was treated initially with trimethoprim/sulphamethoxazole, but there was no clinical improvement. He then received terbinafine (Lamisil) 250 mg twice daily for 6 months. There was rapid resolution of all lesions and complete relief of symptoms, without any associated side-effects. The patient remains clinically well and without any evidence of infection 2 years after discontinuation of terbinafine treatment. 相似文献
20.
Ooka S Kashima M Kubota Y Noguchi A Kawai S Nakamura Y Kano R Watanabe S Hasegawa A Mizoguchi M 《The Journal of dermatology》2000,27(10):658-663
Black dot ringworm (BDR), caused by Trichophyton violaceum var. glabrum (T. glabrum), was observed in a 28-year-old Japanese female who had been treated with prednisolone (22.5 mg/day) for systemic lupus erythematosus. It was successfully treated with oral terbinafine (125 mg/day) for 12 weeks. The causative fungus was identified by molecular analysis as well as morphological and biochemical examination. The chitin synthase 1 (CHS1) gene cleavage pattern of the clinical isolate with restricted enzyme HinfI was identical to that of T. violaceum. We reviewed previous reports of BDR to determine the historical trend of this infection in Japan. Since 1974, 93 Japanese cases have been reported. The age distribution was bi-modal: the higher peak consisted of children (aged 0-15 years), and the lower peak was composed of the elderly (aged 60-75 years). In the elderly group, females were predominant (M:F=1:22, p<0.001). T. violaceum, including T. glabrum, was identified as the most common causative fungus of BDR (75.3%). Sixty percent of cases showed slight erythema. In 8 families, 16 cases were found to be intrafamilial infections. A history of previous steroid treatment was described in about 40%. 相似文献