针刺治疗2型糖尿病100例疗效观察

目的　观察针刺治疗糖尿病的疗效。方法　对 10 0例患者在适当饮食控制的基础上 ,电针脾俞、肾俞、肺俞、胃脘下俞、足三里、内关、三阴交、合谷、血海 ,并辨证加减。结果　治疗后患者空腹血糖值下降 ,与治疗前比 ,P<0 .0 5 ,有显著差异 ;症状明显者由治疗前的 85 %下降到治疗后的 4 %。结论　针刺能降低糖尿病患者空腹血糖 ,在改善临床症状方面亦有明显效果。     

Clinical Observation on Therapeutic Effects of Acupuncture Treatment for 100 Cases of Type Ⅱ Diabetes

目的:观察针刺治疗糖尿病的疗效.方法:对100例患者在适当饮食控制的基础上,电针脾俞、肾俞、肺俞、胃脘下俞、足三里、内关、三阴交、合谷和血海,并辨证加减.结果:治疗后患者空腹血糖值下降,与治疗前比有显著差异(P＜0.05);症状明显者由治疗前的85%下降到治疗后的4%.结论:针刺能降低糖尿病患者空腹血糖,在改善临床症状方面亦有明显效果.     

针刺对Ⅱ型糖尿病患者血清瘦素的影响

目的:探讨瘦素与Ⅱ型糖尿病胰岛素抵抗的关系以及针刺对Ⅱ型糖尿病患者血清瘦素的影响。方法:80例Ⅱ型糖尿病患者随机分为针刺组(40例)和优降糖组(40例)。针刺组以脾俞、肺俞、胰俞、胃俞、肾俞、足三里、三阴交为主穴,结合辨证取穴,每次留针30 min,隔日治疗1次,共12周;优降糖组根据血糖调节剂量持续用药12周。治疗前后检测空腹血糖(葡萄糖氧化酶法)、空腹胰岛素(放射免疫法)、空腹瘦素(酶联免疫法),并计算胰岛素敏感指数和胰岛素抵抗指数。结果:与治疗前比较,针刺组和优降糖组治疗后的空腹血糖、胰岛素抵抗指数均明显下降(P<0.01),胰岛素敏感指数明显回升(P<0.01);针刺组空腹胰岛素和空腹瘦素下降明显(P<0.01),优降糖组空腹胰岛素有所上升(P<0.01)。治疗后,针刺组空腹胰岛素、瘦素及胰岛素抵抗指数均明显低于优降糖组(P<0.01),胰岛素敏感指数针刺组高于优降糖组(P<0.01)。结论:针刺对瘦素的调节可能是其治疗Ⅱ型糖尿病、改善胰岛素抵抗的机制之一。     

针刺治疗2型糖尿病14例临床观察

目的：观察针刺治疗糖尿病的临床疗效。方法：14例糖尿病患者均针刺胆俞、脾俞、胃俞、三阴交、太溪,观察治疗前后血糖变化及相关因素。结果：14例糖尿病患者经针刺治疗总有效率为78．6％,治疗后空腹血糖由（9．29±2．77）mmol／L下降至（7．61±2．65）mmol／L,治疗前后空腹血糖比较有显著性意义（P〈0．05）,餐后血糖由（11．72±2．46）mmol／L下降至（9．59±3．49）mmol／L,治疗前后餐后血糖比较有极显著性意义（P〈0．01）。结论：针刺治疗糖尿病有较好疗效。     

针刺、艾灸、针加灸胃脘下俞穴治疗糖尿病临床观察

目的:评价针刺、艾灸、针加灸胃脘下俞穴治疗糖尿病的临床疗效差异。方法:随机将79例非胰岛素依赖型糖尿病患者分为针刺组(A组)、艾灸组(B组)、针刺加艾灸组(C组),取胃脘下俞穴进行治疗,对治疗前后主要临床症状、空腹血糖、24小时尿糖定量、糖化血红蛋白、血脂进行观察分析比较。结果:治疗后3组患者临床症状明显改善;空腹血糖、24小时尿糖定量、糖化血红蛋白、胆固醇、甘油三酯、低密度脂蛋白均有不同程度降低(P<0.05);高密度脂蛋白均有升高(P<0.05);但以针刺加艾灸组的效果最佳(P<0.01)。结论:无论针刺、艾灸,还是针加灸胃脘下俞穴,都是治疗糖尿病的有效方法,但针刺与艾灸合用效果更好。     

针刺降糖即刻效应的临床观察

目的：观察针刺前后2型糖尿病患者空腹血糖的变化规律。方法：随机选取40例2型糖尿病患者进行为期6天的临床观察,具体方法为：前3日每天早晨7：30和8：00各测定1次空腹血糖并观察其变化情况;后3日每天早晨7：30先测定空腹血糖,然后行针刺治疗,针刺主穴取胰俞、肺俞、脾俞、肾俞、三阴交、太溪,配合辨证配穴,采用补虚泻实手法,留针30min,起针后即刻测定血糖值并与针刺前作比较;每个患者均观察3天,治疗3天,共计6天,观察和治疗期间数据各取平均值后进行统计分析。结果：40例2型糖尿病患者：观察期间7：30空腹血糖平均值7．8mmol·L^-1,8：00空腹血糖平均值7．7mmol·L^-1,二者之间无显著性差异（P〉0．05）;治疗期间7：30空腹血糖平均值7．7mmol·L^-1,治疗后空腹血糖平均值7．1mmol·L^-1,治疗前后有显著性差异（P〈0．05）;观察期8：00和治疗期8：00患者血糖值比较有显著性差异（P〈0．05）。结论：针刺有较好的即刻降糖效应,降糖范围在0．2～1．5mmol·L^-1之间。     

针刺降糖即刻效应观察

目的:验证针刺对Ⅱ型糖尿病患者的即时降糖效应.方法:40例Ⅱ型糖尿病患者针刺前3日每天早晨7:30和8:00各测定一次空腹血糖并观察其变化情况;然后行针刺治疗3天,穴取胰俞、肺俞、脾俞、肾俞、三阴交、太溪,配合辨证取穴,留针30 min,起针后即刻测定血糖值并与针刺前作比较.结果:针刺前3日7:30空腹血糖值与8:00...     

针药并用治疗糖尿病神经病变疗效观察

目的：探讨糖尿病神经病变的较佳治疗方法。方法：将患者随机分成针刺组30例、对照组26例。对照组服用格列齐特80mg／d控制血糖，口服腺苷辅酶B12片0．75mg，以改善神经系统营养；针刺组在此基础上，针刺双侧胰俞穴，两组疗程均为3周，观察两组疗效及空腹血糖、空腹尿糖、血脂的变化。结果：针刺组总有效率为93．3％，对照组为67．3％。针刺组空腹血糖G、空腹尿糖GLU、胆固醇（TC）、甘油三脂（TG）明显下降，高密度脂蛋白（HDL）显著上升，与对照组比较差异亦有显著性意义（均P〈0．05）。结论：针刺加药物能较好地改善早、中期糖尿病患者脂肪代谢紊乱，具有降低和稳定血糖以及改善神经功能的作用。     

针刺治疗慢性萎缩性胃炎56例临床观察

目的：观察针刺治疗慢性萎缩性胃炎的临床疗效。方法：慢性萎缩性胃炎患者56例给予针刺主穴足三里、中脘、内关、脾俞、胃俞穴位治疗4周后观察临床疗效，对治疗前后临床症状体征、胃黏膜病理变化进行比较。结果：治疗后胃痛、消化不良、嗳气、少食和脘腹胀满等症状和胃黏膜病理变化均较治疗前有明显改善，积分与治疗前相比有显著性差异（P〈0．01）。结论：针刺治疗能改善慢性萎缩性胃炎的临床症状体征、胃黏膜病理状态。     

针刺胃俞募穴联合健脾固本和胃方对糖尿病胃轻瘫患者血浆Ghrelin的影响

目的:观察针刺胃俞募穴联合健脾固本和胃方对2型糖尿病胃轻瘫患者血浆Ghrelin水平的影响。方法:108例符合纳入标准的糖尿病胃轻瘫患者随机分为针药结合组、针刺组和中药组,针药结合组采用针刺胃俞募穴联合健脾固本和胃方治疗2型糖尿病胃轻瘫患者,与针刺组(针刺胃俞募穴)、健脾固本和胃方组(口服健脾固本和胃方)对照,观察治疗前后血浆Ghrelin的变化,探讨针刺胃俞募穴联合健脾固本和胃方治疗2型糖尿病胃轻瘫的可能作用机制。结果:3组治疗后的Ghrelin水平较治疗前均有明显下降(P0.01,P0.05),而治疗后针刺组与针药结合组的Ghrelin水平比较无统计学差异(P0.05)。针药结合组与中药组、针刺组与中药组的Ghrelin水平相比均有统计学差异(P0.01)。结论:针刺胃俞募穴联合健脾固本和胃方能有效提高2型糖尿病胃轻瘫血浆Ghrelin水平,且针刺发挥主导作用。     

降糖精颗粒治疗2型糖尿病疗效观察及机制探讨

目的: 观察降糖精颗粒治疗2型糖尿病的疗效及其降糖机制的初步探讨。 方法: 将40例2型糖尿病患者随机分为降糖精组和对照组。通过8周的观察,比较2组患者血糖、糖化血红蛋白(HbAlc)和中医症状积分的变化。 结果: 2 组用药前各项指标无显著差异;用药后,降糖精组空腹血糖、餐后2 h血糖、HbAlc较治疗前比较有统计学差异(P<0.05);与对照组比较无统计学差异。但治疗8周时降糖精组症状明显减轻,与对照组比较有统计学差异(P<0.05)。 结论: 降糖精颗粒能改善2型糖尿病患者的糖代谢,减轻患者相关中医症状,其机制可能与调节患者的肠促胰素(GLP-1)有关。     

中医辨证点穴法对2型糖尿病患者血糖和胰岛功能作用的临床研究

[目的]观察中医辨证点穴法对2型糖尿病患者血糖及胰岛功能的临床效果。[方法]选择符合入选标准的160例2型糖尿病患者,按病程长短进行分层分为初发组、1~3 a组,3~5 a组,每层随机分为治疗组及对照组,对照组采用常规降糖治疗,治疗组在此基础上加用中医辨证点穴方法治疗,治疗2周后比较两组血糖、症状积分、HOMA指数、胰岛第1时相功能、胰岛第2时相功能。[结果]治疗组总有效率优于对照组,P0.05,在血糖控制、症状改善上均优于对照组(P0.05),稳态评估模型(HOMA)指数、胰岛第1时相功能明显高于对照组(P0.01或0.05)具有统计学差异。[结论]中医辨证点穴方法能有效改善2型糖尿病患者症状、有效控制血糖,对胰岛功能亦有一定恢复作用,有推广应用价值,需进一步深入研究。     

Acupuncture treatment of female urethral syndrome

Purpose To observe the curative effect of acupuncture on female urethral syndrome.Method A treatment group of 30 patients were treated with acupuncture at points Zhongji (CV 3), Zusanli (ST 36), Sanyinjiao (SP 6), Shenshu (BL 23), Pangguangshu (BL 28), Guanyuan (CV 4), Zhaohai (KI 6) and Zhonglushu (BL 29). A control group of 28 patients were treated with capsule Norfloxacini and capsule Cystocaps.Results Of the treatment group, 26 patients had effectiveness and 4 had ineffectiveness; of the control group, 2 patients had effectiveness and 26 had ineffectiveness. There was a significant difference in effective rate between the two groups (P<0.01).Conclusion The curative effect of acupuncture on female urethral syndrome is better than that of routine treatment. Translator: WANG Si-you     

Randomized controlled study on effects of the needling method for regulating spleen-stomach on coronary heart disease complicated by type 2 diabetes mellitus complicated

OBJECTIVE: To probe into the clinical therapeutic effect of acupuncture on coronary heart disease complicated by type 2 diabetes mellitus (CDM) and the mechanism. METHODS: Using multi-central, randomized, controlled and blind methods, 120 cases of CDM were divided into an observation group and a control group, 60 cases in each group. They were treated by routine therapy for diabetes mellitus, and in the observation group, acupuncture at Quchi (LI 11), Hegu (LI 4), Xuehai (SP 10), Zusanli (ST 36), Yinlingquan (SP 9), Fenglong (ST 40). Diji (SP 8), Sanyinjiao (SP 6), etc. were added with the needling method for regulating spleen-stomach; while in the control group, acupuncture was given at Weiwanxiashu (EX-B 3), Feishu (BL 13), Pishu (BL 20), Shenshu (BL 23), Yanglingquan (GB 34), etc. The treatment was given twice a day in the two groups. Clinical therapeutic effects were assessed according to clinical symptoms and signs, frequency and lasting time of angina pectoris, quantity of taking Glycerol Trinitrate, blood sugar, blood lipids, urinary albumin excretion rate, urinary beta2-microglobulin, urinary monocyte chemotactic protein-1 (MCP-1), ECG, heart color Doppler, etc. RESULTS: The needling method for regulating spleen-stomach not only could improve the symptoms and signs of the patient, but also could improve the degree of ST segment moving down and the function of left artrium relaxation, and had benign regulative effect on glycometabolism, lipids metabolism and urinary albumin level, with significant differences as compared with the control group (P < 0.05 or P < 0.01). The markedly effective rate for improvement of ECG was 50.00% in the observation group and 13.79% in the control group. CONCLUSION: The needling method for regulating spleen-stomach can improve the damage of heart and blood vessels induced by abnormal sugar and lipids, decrease the level of urinary protein, inhibit MCP-1 excessive expression, relieve myocardial load and raise cardiac output in the patient of coronary heart disease complicated by type 2 diabetes mellitus.     

Acupuncture for chronic prostatitis: A randomized controlled trial: 针刺治疗慢性前列腺炎:随机对照研究

ObjectiveTo explore whether there is a specific clinical effect of acupuncture in the treatment of chronic prostatitis.MethodsA total of 52 patients with chronic prostatitis were randomly divided into an acupuncture group (24 cases) and a placebo acupuncture group (28 cases). During the treatment, 1 case was dropped out in the placebo acupuncture group and 51 patients accomplished the clinical trial finally in two groups. In the acupuncture group, Shènshū (肾俞BL23), Zhōngliáo (中髎BL33), Huìyáng (会阳BL35) and Sānyīnjiāo (三阴交SP6) were selected. In the placebo acupuncture group, the non-meridian points located lateral to BL23, BL33, BL35 and SP6 were selected, respectively. The duration of treatment was 8 weeks in each group. In the first 4 weeks of treatment, the treatment was given once every two days, three times weekly. In the last 4 weeks of treatment, the treatment was given once every three days, twice a week. Totally, 20 acupuncture treatments were required in the whole trial. Before treatment, in week 4 and 8 of treatment and in follow-up, National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) score and the comprehensive effect were evaluated in the two groups successively.ResultsIn week 4 and 8 of treatment, NIH-CPSI score in the acupuncture group was lower than that before treatment, respectively (both P < 0.05). In week 8 of treatment, NIH-CPSI score in the placebo acupuncture group was lower than that before treatment (P < 0.05). NIH-CPSI score in the acupuncture group was lower than the placebo acupuncture group in week 8 of treatment (P < 0.05). In follow-up, NIH-CPSI score of the two groups all decreased as compared with the score before treatment (both P < 0.05), and the score in the acupuncture group was lower than the placebo acupuncture group (P < 0.05). In the comparison of comprehensive effect, the total effective rate was 91.7% in the acupuncture group and was 74.1% in the placebo acupuncture group. The therapeutic effect in the acupuncture group was better than that of the placebo acupuncture group (P < 0.05).ConclusionAcupuncture relieves pelvic pain and urination symptoms and has a certain of long-term effect in patients with chronic prostatitis.     

化浊解毒方联合二甲双胍对2型糖尿病患者肠促胰素GLP-1的影响

[目的]观察化浊解毒方联合二甲双胍对2型糖尿病(T2DM)患者血清胰高血糖素样肽-1(GLP-1)的影响。[方法]筛选符合浊毒内蕴证型的T2DM患者,随机分为治疗组和对照组。治疗组在常规治疗基础上加服化浊解毒方,8周后评价患者临床证候的改善情况,检测血糖、胰岛素及GLP-1等相关指标。[结果]治疗后,治疗组较对照组临床症状体征明显改善,血糖、糖化血红蛋白水平明显降低(P0.05),GLP-1分泌显著增加(P0.01),胰岛素水平无明显变化。[结论]化浊解毒方联合二甲双胍能增加T2DM患者GLP-1分泌,从而增强其降糖疗效。     

基于胃肠激素水平变化探讨调理脾胃针法治疗糖尿病性胃轻瘫的疗效机制

[目的]观察调理脾胃针法治疗糖尿病性胃轻瘫的临床疗效,探讨其对胃肠激素水平的影响。[方法]将符合纳入标准的70例糖尿病性胃轻瘫患者按照随机数字表法随机分为观察组、对照组各35例。两组患者在糖尿病基础治疗的同时,对照组口服枸橼酸莫沙必利分散片5 mg,每日3次,餐前口服,观察组采用调理脾胃针法,取穴:中脘、足三里、阴陵泉、血海、三阴交、地机、曲池、合谷、丰隆、太冲、内关、公孙。连续治疗6周。分别于治疗前后对临床症状评分、综合疗效、跨膜蛋白16A(ANO1)、胃肠激素水平进行评定,将结果进行统计学分析。[结果]观察组临床总有效率为88.57%,对照组为68.57%,在胃轻瘫主要症状评定方面两组治疗方法均可以提高患者各症状积分及总体症状积分,但在嗳气、腹胀、食欲不振、恶心呕吐、总体症状积分、ANO1及胃肠激素水平改善方面,观察组优于对照组(P<0.01)。[结论]调理脾胃针法可明显改善糖尿病性胃轻瘫患者的临床症状,提高总有效率,降低ANO1含量,改善胃肠激素水平,其疗效优于单纯西药,且安全可靠。     

乌梅丸合八珍汤加减治疗肥胖2型糖尿病气阴两虚夹痰瘀证临床观察

目的:观察乌梅丸合八珍汤加减治疗肥胖2型糖尿病气阴两虚夹痰瘀证的临床疗效。方法:将选取符合纳入标准的60例肥胖2型糖尿病气阴两虚夹痰瘀证患者按照随机数字法分为观察组、对照组,各30例。在糖尿病常规治疗基础上,观察组给予西医(盐酸二甲双胍)治疗,同时应用乌梅丸合八珍汤加减治疗。对照组采用常规西药(盐酸二甲双胍)治疗。疗程为8周,比较两组患者治疗前后空腹血糖(FPG),餐后2 h血糖(2 h PG),糖化血红蛋白(HbA1c),总胆固醇(TC),三酰甘油(TG),体质量指数(BMI)水平、安全性指标(三大常规、肝肾功能)及临床症状的变化情况,并评价两组患者临床疗效。结果:观察组症状评分有效率为93. 3%(28/30),明显高于对照组的73. 3%(22/30)(P 0. 05)。与本组治疗前比较,治疗后两组患者FPG,2 h PG,HbA1c水平均明显降低,且观察组治疗后FPG,2 h PG,HbA1c明显低于对照组(P 0. 05);两组患者治疗后TC,TG,BMI水平及中医证候积分均明显降低(P 0. 05),且观察组治疗后TC,TG,BMI水平及中医证候积分低于对照组(P 0. 05)。结论:乌梅丸合八珍汤对治疗肥胖2型糖尿病气阴两虚夹痰瘀证患者安全有效,且能降低患者血糖,血脂,BMI水平及减轻患者临床症状具有显著的疗效,值得推广。