导管射频消融右室流出道特发性室速两种标测方法的比较

目的评价连续起搏标测法指导右室流出道(RVOT)室速导管射频消融治疗的价值.方法选择经电生理检查确诊且适合导管消融治疗的连续27例RVOT室速病例进入观察,按随机数字表法分为间断起搏标测组和连续起搏标测组.结果间断起搏标测组11例标测成功,另3例需改用连续起搏标测,无操作并发症,随访2.1±0.7年无室速复发.连续起搏标测组11例标测成功,另2例在连续起搏下移动导管时多次诱发短阵尖端扭转性室速,改用间断起搏标测法消融成功,无操作并发症,随访1.9±0.8年无室速复发.结论该方法可作为间断起搏标测法的重要补充用于RVOT室速病人的导管射频消融治疗.     

导管射频消融右室流出道特发性室速两种标测方法的比较

目的评价连续起搏标测法指导右室流出道(RVOT)室速导管射频消融治疗的价值.方法选择经电生理检查确诊且适合导管消融治疗的连续27例RVOT室速病例进入观察,按随机数字表法分为间断起搏标测组和连续起搏标测组.结果间断起搏标测组11例标测成功,另3例需改用连续起搏标测,无操作并发症,随访2.1±0.7年无室速复发.连续起搏标测组11例标测成功,另2例在连续起搏下移动导管时多次诱发短阵尖端扭转性室速,改用间断起搏标测法消融成功,无操作并发症,随访1.9±0.8年无室速复发.结论该方法可作为间断起搏标测法的重要补充用于RVOT室速病人的导管射频消融治疗.     

XC—1心脏标测计时仪的研制及其应用

本文介绍了XC-1心脏标测计时仪的心外膜标测方法,电路原理及临床应用。     

心房心外膜标测电极的研制

介绍一种心房心外膜多位点标测电极－电极板电极的制作方法。该电极简便易行。标测所得双极电图形尖锐、清晰、基线平稳，与计算机辅助的信号处理系统相连可用于房性心律失常的心外实时标测。     

特发性室性心动过速的导管射频消融临床体会

目的 回顾性分析导管射频消融(RFCA)治疗特发性室性心动过速(IVT)的疗效,以进一步指导相关临床工作.方法 对34例TVT患者进行RFCA治疗,左室特发性室性心动过速(ILVT)采用激动标测的方法或起搏标测与最早QRS波相结合的方法标测靶点;对右室特发性室性心动过速采用起搏标测的方法标测靶点,标测靶点后放电消融.结果 34例患者行心内电生理检查时均诱发出室性心动过速.30例治疗成功,患者的临床症状消失,无手术相关的并发症,4例失败,4例随访期间复发,再次RFCA治疗成功.结论 RFCA能够根治IVT,成功率高、安全,可作为治疗IVT首选方法.     

特发性室性心动过速的导管射频消融临床体会

目的回顾性分析导管射频消融（RFCA）治疗特发性室性心动过速（IVT）的疗效，以进一步指导相关临床工作。方法对34例IVT患者进行RFCA治疗，左室特发性室性心动过速（ILVT）采用激动标测的方法或起搏标测与最早QRS波相结合的方法标测靶点；对右室特发性室性心动过速采用起搏标测的方法标测靶点，标测靶点后放电消融。结果34例患者行心内电生理检查时均诱发出室性心动过速。30例治疗成功，患者的临床症状消失，无手术相关的并发症，4例失败，4例随访期间复发，再次RFCA治疗成功。结论RFCA能够根治IVT，成功率高、安全，可作为治疗IVT首选方法。     

一种用于心外膜动态标测三维仿真的方法

利用高性能三维图形处理标准OpenGL实现全心房心外膜标测,画出三维标测图.文中对三维模型数据的产生、读入以及操作等给出了部分代码.     

计算机辅助预激综合症心外膜标测系统的研制

本文报告了计算机辅助预激综合征心外膜标测系统的研制。系统具有以下特点:自动显示和绘出心外膜激动顺序图;网套电极对53个区全部采样;计算机实时标测;标测时间短,定位精确度高。文中给出实验结果。     

新技术介绍——EnSite系统

EnSite系统是当前最先进的三维电生理标测与导航系统,可用于所有心律失常的标测.该系统发展迅速,目前包括EnSite Array与EnSite NavX两个部分.……     

新技术介绍——EnSite系统

<正>EnSite系统是当前最先进的三维电生理标测与导航系统,可用于所有心律失常的标测。该系统发展迅速,目前包括EnSite Array与EnSite NavX两个部分。 EnSite ArrayTM 只需被检查者”心脏一跳”,即可完成心律失常的非接触性实时标测。因为该系统有独一无二的非接触性EnSite Array多电极导管具有64个电极,其独特的     

Calcium intake in the elderly: validation of a dietary questionnaire

Epidemiological studies of calcium and osteoporosis have been hampered by the lack of a suitable tool for assessing calcium intake. This report describes a new frequency and amount questionnaire for measuring present and past calcium intake in the elderly. The validity of the questionnaire was tested against two commonly used standards of dietary assessment, five-day duplicate diets and seven-day weighed dietary inventories. The resulting correlation coefficients were, respectively, r = 0.76 and r = 0.69, while that for repeatability was r = 0.84. Furthermore, the questionnaire categorized subjects into thirds of the distribution of intake with almost no gross misclassification. It is suggested that the present findings may be extended to the majority of normal, healthy elderly subjects, implying wide application for the questionnaire in the assessment of calcium intake in the elderly.     

Self-reported health problems among Swedish miners one year after unemployment

Unemployment is considered to be a public health concern sincedeterioration in the health of the unemployed is often anticipated.However, for some groups, such as miners, unemployment mightimprove health due to a cessation of potentially harmful occupationalexposures. This study evaluates the health of 79 miners in oneSwedish iron-ore mine, and 226 age-matched controls from thegeneral population, during one year after the closure of themine. The participants received a questionnaire regarding medicalhistory and subjective symptoms at the beginning of the studyperiod, and after one year. Statistically significant negativeeffects on self-reported health attributable to unemploymentwere not found, although neuropsychiatric symptoms were morecommon among the unemployed miners. The miners reported a statisticallysignificant improvement in grip force (p=0.031). They had asignificantly higher prevalence of symptoms associated withmining related exposures when compared with the population controls;pain in the upper extremities [relative risk (RR)=2.27, 95%confidence interval (Cl)=1.44–3.59), back pain (RR=1.84;Cl=1.237–2.75), vasospastic disease of the fingers (RR=2.05;Cl=1.18–3.57) and obstructive respiratory symptoms (attacksof dyspnea and wheezing: RR=3.67; Cl=1.167–11.6).     

Excès de cas humains et animaux de tularémie en France au cours de l’hiver 2007–2008 : émergence ou phénomène isolé ?

Context

Tularemia is a zoonosis affecting humans and hares in France. We describe the results of surveillance in both species, in 2007 and 2008.

Methods

Human tularemia cases are mandatorily notifiable in France since 2003. In hares, surveillance relies on volunteer hunter associations in all districts of the country. Data from mandatory reports and volunteer surveillance in 2007/2008 were analyzed and compared with previous results.

Results

In 2007/2008, 144 cases were reported in humans and 117 cases in hares. This was a 100% increase compared to previous years. Human cases differed from those of previous years only by the frequency of contact with breeding animals. Human cases without any documented risk exposure were also more frequent.

Conclusion

An increase of tularemia cases occurred in 2007/2008 in both species. Complementary studies are needed to identify the species reservoir in France to understand the causes of this peak of cases.     

Occupational health hazards in mining: an overview

This review article outlines the physical, chemical, biological, ergonomic and psychosocial occupational health hazards of mining and associated metallurgical processes. Mining remains an important industrial sector in many parts of the world and although substantial progress has been made in the control of occupational health hazards, there remains room for further risk reduction. This applies particularly to traumatic injury hazards, ergonomic hazards and noise. Vigilance is also required to ensure exposures to coal dust and crystalline silica remain effectively controlled.     

Manufacture and use of nanomaterials: current status in the UK and global trends

This paper provides an overview of the production and use of nanomaterials (NMs), particularly in the UK. Currently, relatively few companies in the UK are identifiable as NM manufacturers, the main emphasis being the bulk markets in metals and metal oxides, and some niche markets such as carbon nanotubes and quantum dots. NM manufacturing in the UK does not reflect the global emphasis on fullerenes, nanotubes and fibres. Some assumptions have been made about the types of NM that are likely to be imported into the UK, which currently include fullerenes, modified fullerenes and other carbon-based NMs including nanotubes. Many university departments, spin-offs and private companies have developed processes for the manufacture of NMs but may only be producing small quantities for research and development (R&D) purposes. However, some have the potential to scale up to produce large quantities. The nanotechnology industry in the UK has strong R&D backup from universities and related institutions. This review has covered R&D trends at such institutions, and appropriate information has been added to a searchable database. While several companies are including NMs in their products, only a few (e.g. manufacturers of paints, coatings, cosmetics, catalysts, polymer composites) are using nanoparticles (NPs) in any significant quantities. However, this situation is likely to change rapidly. There is a need to collect more information about exposure to NPs in both manufacturing and user scenarios. As the market grows, and as manufacturers switch from the micro- to the nanoscale, the potential for exposure will increase. More research is required to quantify any risks to workers and consumers.     

深圳公立医院管理体制改革制度设计

深圳公立医院管理体制改革实行政事分开、管办分开,在理事会架构下按法定机构模式组建市医管中心,落实公立医院运营管理自主权.作者从当前公立医院管理体制的弊端入手,介绍了深圳市进行公立医院管理体制改革的基本思路及改革方案设计的主要举措,深入剖析了的改革方案的特点,并对改革效果进行了预测.     

Effects of nitrogen dioxide on red blood cells of rats: Changes in components of red cell membranes during in vivo exposure to NO2

Red cell membranes, prepared from red blood cells of rats exposed to 4, 10, or 20 ppm nitrogen dioxide (NO₂) for 1 to 10 days, were examined for evidence of changes in membrane components. Appreciable changes were not found in contents of phospholipid and cholesterol during exposure to 10 ppm NO₂. By contrast, protein content altered with the time of exposure. Moreover, changes in protein composition were observed by employing sodium dodecyl sulfate — polyacrylamide gel electrophoresis. Twenty-four-hour exposure to NO₂ at the concentration above 10 ppm resulted in a marked increase in the percentage of lysophosphatidylethanolamine (LysoPE) to the total phospholipids. The prolonged exposure to 10 ppm NO₂ gave rise to a further increase in LysoPE, whereas the percentage of phosphatidylethanolamine (PE) showed a gradual decrease. A 1-day exposure to 4.0 ppm NO₂ also caused an increase in sialic acid content and decreases in those of PE and hexose. In addition to contents of these components the percentage of LysoPE increased 5 days after exposure and the elevated values were maintained up to the end of exposure period. These results demonstrate that red blood cells in circulation exhibit different membrane properties in terms of lipid and carbohydrate composition during 10 days of exposure to 4.0 ppm NO₂.     

Investigating clusters in the workplace and beyond

Clusters of disease are common and occur in the workplace and in the general community. They often arouse considerable concern among the population. Investigations have sometimes lead to exciting new knowledge, but in general the investigation of clusters is difficult and often unrewarding, especially for community clusters. In the workplace, investigations are more likely to find associations and even new causes, but still many clusters remain enigmatic. Despite this, there are many reasons for investigating clusters, including allaying community concern and identifying uncontrolled exposures. A structure for investigating clusters in the workplace is suggested.