原发性腹膜后黏液性囊腺瘤1例报告并文献复习

目的：探讨原发性腹膜后黏液性囊腺瘤的临床及病理特点。方法：回顾性分析1例原发性腹膜后黏液性囊腺瘤患者的临床资料：患者女,29岁。19个月前体检时B超发现腹膜后右肾下极有3．5cm×2．4cm无回声占位性病变,内无明显血流信号。患者每6个月进行一次影像学复查,肿物体积未见明显变化。血清Ca199、Ca125、CEA等指标均在正常范围。患者在全麻下行腹腔镜腹膜后肿瘤切除术。并检索Pubmed和CBM数据库,对该疾病相关文献进行复习。结果：术后病理检查诊断为腹膜后交界性黏液性囊腺瘤。术后随访2个月,未见肿瘤复发。结论：腹膜后黏液性囊腺瘤是一种罕见的腹膜后肿瘤,诊断该病主要依靠术后病理检查。该肿瘤的体积及生长速度与肿瘤的恶性程度无确定关系。腹腔镜手术治疗腹膜后黏液性囊腺瘤安全有效。     

前列腺黏液腺癌2例报告及文献复习

目的：探讨前列腺黏液腺癌的病理和诊疗特点。方法：回顾性分析我院1995年1月～2011年3月收治的2例前列腺黏液腺癌患者的临床资料,并结合文献复习,分析其特点。结果：2例患者年龄分别为73和84岁,因不同程度的排尿困难入院。1例误诊为前列腺增生,行经尿道前列腺电切术;另1例直肠指检、B超、CT、MRI及PSA检查均提示为前列腺癌,行穿刺活检后确诊,根据患者全身状况行硬膜外麻醉下经尿道前列腺电切术,以改善排尿症状,术后病理检查回报为前列腺黏液腺癌,免疫组织化学检查有较特异性表现。术后给予抗雄激素治疗等。结论：前列腺黏液腺癌在前列腺癌中罕见,没有特征性的临床表现,确诊主要依靠病理和免疫组织化学检查;治疗方法可采用根治性前列腺切除术。     

Villous Mucinous Cystadenoma of the Appendix in a Postmenopausal Woman

Objective:

To present the case of a postmenopausal woman, who was suspected of having an ovarian cyst. Instead, a cystadenoma of the appendix was discovered during laparoscopy.

Methods:

A 64-year-old postmenopausal nulliparous woman was admitted to our hospital because of a cystic lesion, which had been detected in the course of a routine gynecological examination. The patient underwent vaginal ultrasound, magnetic resonance tomography, and laparoscopy.

Results:

During vaginal ultrasound, a dumbbell-shaped anechogenic cystic structure 70 × 32 × 22 mm in diameter was found in the region of the right adnexa. Magnetic resonance tomography revealed no additional information. During diagnostic laparoscopy, the cystic lesion was found to be a distended appendix. A laparoscopic appendectomy was performed. Subsequent histological analysis revealed a villous mucinous cystadenoma of the appendix with low-grade intraepithelial neoplasia.

Conclusion:

Gynecologists should routinely consider this disease in the differential diagnosis of right lower dumbbell abdominal cysts. Eleven percent to 20% of mucoceles are caused by mucinous cystadenocarcinomas, which carry the risk of peritoneal tumor implantation caused by rupture or laparoscopic resection. Therefore, it should be mandatory that a general surgeon be involved in the laparoscopic procedure and the conversion to laparotomy for resection of the structure.     

Acinar Cell Cystadenoma of the Pancreas: Report of Three Cases and Literature Review

Introduction

Acinar cell cystadenoma (ACC) of the pancreas was first described as a distinct pancreatic cystic neoplasm in 2002.

Methods

We have encountered three cases of ACC at our institution in addition to the 15 cases reported to date in the world literature. The gender distribution in the total cohort of patients with ACC slightly favored females (61 % female), and the median age was 49.5 years.

Results

Almost half (53 %) of the cases were identified incidentally, while the remainder presented with abdominal pain. The median tumor diameter was 5 cm in size, and no patients have had documented disease recurrence or progression, even in the setting of an incomplete resection.

Conclusion

These findings suggest a relatively indolent biology, and that complete resections are curative. As we will show, surgical resection is warranted to treat symptoms and prevent local extension or malignant transformation.     

Papillary Cystadenoma of Minor Salivary Glands: Report of 11 Cases and Review of the English Literature

Papillary cystadenoma is a rare, benign salivary gland tumor which is well-circumscribed, containing cystic cavities with intraluminal papillary projections. Only 19 cases arising within minor salivary glands (MnSG) from the oral cavity sites have been reported in the English literature (PubMed 1958–2014). We report 11 new cases of MnSG papillary cystadenomas in conjunction with a review of the literature. Demographic information, clinical and histologic features, treatment and prognosis are compiled and discussed for all 30 cases reported in the English literature.     

Mucocele of the Appendix: Case Report and Review of Literature

Appendiceal mucocele is a rare disease. Sometimes it is discovered accidentally and sometimes it resembles acute appendicitis. Correct diagnosis before surgery is very important for the selection of adequate surgical treatment to avoid intraoperative and postoperative complications. Ultrasonography, and particularly computed tomography, should be used extensively for this purpose. If mucocele is treated incorrectly pseudomyxoma peritonei, which is characterized by malignant process, may develop. We present a case of a 54-year-old man who was admitted to the emergency department with the signs of acute appendicitis. Open surgery was performed. At the time of surgery, a cystic mass of the appendix with dimensions 7 × 4 ×3 cm, with inflamed walls, but without perforation was discovered in the right iliac fossa. No discharge was found in the peritoneal cavity. Diagnosis of mucocele was suspected. Only appendectomy was performed because no pathologic process was found in the base of the appendix and lymph nodes were not increased in size. Hystopathologic diagnosis was mucinous cystadenoma. After 2 years, the patient is feeling well.     

Atypical Presentations of Benign Retroperitoneal Schwannoma: Report of Three Cases with Review of Literature

We report 3 cases of benign retroperitoneal schwannoma, of whom one presented with flank pain with hematuria, one presented with headache and secondary hypertension and one presented with recurrent renal colicky pain. Two patients were treated by open surgical excision of the tumor with nephrectomy of the corresponding side because the tumors were densely adhered to the kidney and one case treated by laparoscopic resection of the mass only. The diagnosis of schwannoma was established postoperatively after histopathological examination and immunohistochemistry. All patients are doing well in follow-up.     

Large Mucinous Cystadenoma of the Pancreas During Pregnancy: Report of a Case

A 33-year-old woman, gravida 2, para 1, was diagnosed to have a benign mucinous cystic neoplasm of the pancreas 5 months before delivery. The tumor measured 12 cm in diameter at the time of diagnosis. The antenatal course was uneventful, and a vaginal delivery produced a normal infant. By 2 months after delivery, the tumor reached 18 cm. At surgery, a huge cyst was found to originate from the pancreas, and a distal pancreatectomy with splenectomy was performed. The cystic mass was multilocular 18 × 17 × 12 cm, 2450 g, and red to yellowish-gray. The histologic diagnosis was benign mucinous cystadenoma. The postoperative course was uneventful, and the patient remains free of recurrence at 7 months after surgery. To our knowledge, this is only the fifth reported case of pancreatic mucinous cystadenoma in association with pregnancy. This is the first reported case of a successful resection of such a tumor after delivery.     

Segmental Odontomaxillary Dysplasia: Report of 3 Cases and Literature Review

Segmental Odontomaxillary Dysplasia (SOD) is an uncommon developmental disorder of unknown etiology that causes a unilateral alteration of the maxilla associated with an abnormal growth and maturation of bone, lack of one or both premolars and delayed tooth eruption on the affected side, alteration of adjacent gingival tissue with or without facial cutaneous lesions. Radiographically is observed an irregular trabecular pattern and reduction of the maxillary sinus. There are 50 cases reported in the English-language literature. A literature review is herein presented emphasizing the clinical, radiographic, and histological features, and three additional cases of SOD affecting a 22 years-old woman, a 18 years-old man, and a 5 years-old boy, respectively are described.     

Salivary Oncocytic Cystadenoma with Intraluminal Crystalloids: a Case Report with Review of the Literature

Oncocytic cystadenoma is a rare benign tumor of major salivary glands that in rare occasions may present histologically with intraluminal crystalloids. We report a case of 53-year-old man with a progressively enlarging lump in the left submandibular region. Ultrasound examination revealed a cystic mass with an intraluminal fluid collection. The tumor was surgically removed. Histologic examination yielded a diagnosis of oncocytic cystadenoma with a high concentration of intraluminal crystalloids. The microscopic features of the crystalloids were compatible with nontyrosine (alpha-amylase) crystalloids. When compared with previously published cases in the literature, this is the first report of oncocytic cystadenoma with intraluminal crystalloids arising in the submandibular gland, and the second reported case of the nontyrosine type of crystalloids occurring in association with this tumor. The nontyrosine crystalloids may be highly characteristic to salivary gland tumors with oncocytic differentiation.     

脊柱骨软骨瘤3例报告附中国文献复习

脊柱骨软骨瘤较少见,１９６９年来我院共收治３例,其中１例为骨软骨瘤病。病变部位：Ｃ４、Ｃ５及Ｔ１２各１例４个病变,压迫脊髓的３个病变均起源于椎板。经手术治疗,两例有脊髓压迫症状者完全恢复,１例瘫痪者随访两年无改善。复习中国所报告的脊柱骨软骨瘤共计３２例３４个病变,平均病程１４个月,年龄３４５岁,男女比为２∶１。脊柱各阶段均有病变报道,以颈胸椎为多,按平均每个椎体发生病变的机会则依次为颈、腰、胸、骶椎。脊椎各部均可发生病变,以椎板、椎体及关节突为多。治疗均采用手术切除。影响预后的主要因素是术前神经功能已受损情况及肿瘤的位置。     

血清阴性类风湿关节炎3例并文献复习

类风湿关节炎(rheumatoid arthritis,RA)是一种以侵蚀性关节炎为主要表现的全身性自身免疫性疾病.近年来,多种研究表明,RA 患者体内存在多种自身抗体,例如类风湿因子(RF)、抗角蛋白抗体(AKA)、抗核周因子(APF)及抗环瓜氨酸肽抗体(抗CCP 抗体)等.RA 是一种异质性疾病,一部分患者RF 和...     

胃泌素瘤2例报道并文献复习

目的探讨胃泌素瘤的诊断和治疗经验。方法回顾绵阳市中心医院确诊的2例胃泌素瘤患者的临床资料,并结合相关文献分析。结果2例均表现为难治性消化性溃疡,CT检查发现胰腺包块,生化与病理检测确诊为胃泌素瘤。结论对多发性、异位、顽固性消化性溃疡应警惕本病的存在,以免延误诊治。     

Skull Metastasis From Intrahepatic Cholangiocarcinoma: Report of 3 Cases and Review of the Literature

Skull metastases occur in patients with various malignancies; however, those resulting from intrahepatic cholangiocarcinoma (ICC) have been rarely reported. In our hospital, 324 patients were diagnosed with metastatic brain or skull tumors from June 1969 to June 2011, but only 3 of them (0.9%) developed skull metastases from ICC. We report the case of 3 patients with skull metastases from ICC. A combination of computed tomography (CT), contrast-enhanced magnetic resonance imaging (MRI), 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), and methionine-PET were used for imaging. Sites of tumors were the lateral left orbit and right parietal bone in case 1, the left parietal bone, left temporal bone, and lateral left orbit in case 2, the right petrous bone, right occipital bone, and upper cervical vertebra in case 3. The metastases were confirmed to have originated from ICC by biopsy in two of the cases and diagnosed by MRI and FDG-PET in case 2. Radiosurgery and radiotherapy had positive effects on symptom improvement and cosmetic problems.     

Thoracic Intradural Extramedullary Lipomas. Report of Three Cases and Review of the Literature

Summary. Summary. Background: Indication for surgery and the surgical strategy for treatment of spinal intradural lipomas are still discussed controversially. Among spinal lipomas the cervicothoracic region is rarely affected. We report on our experience with spinal decompression for the treatment of three intradural thoracic lipomas. Findings: Three adult patients with extramedullary intradural lipomas of the thoracic spinal cord demonstrated progressive neurological symptoms and signs without evidence of growth of the lipoma. All patients underwent surgery with decompression of the affected spinal levels. No attempt was made to reduce the size of the lipomas. Postoperatively, each patient demonstrated significant clinical improvement. Interpretation: Attempts to remove lipomas are associated with significant risks of surgical morbidity. Lipomas are hamartomas which change their size according to alterations of body fat. Therefore, decompression of the affected spinal levels is sufficient to achieve significant neurological improvement.