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1.
[目的]探讨螺旋CT引导下经皮穿刺卵圆孔注射阿霉素联合无水酒精毁损疗法治疗三叉神经痛的技术及临床应用价值.[方法]本院收治的45例三叉神经痛患者采用螺旋CT引导经皮穿刺卵圆孔,缓慢注射无水酒精和阿霉素0.2~0.5 mL.采用视觉模拟疼痛评分 (VAS)测定疼痛强度.[结果]45例治疗后,即刻疼痛完全缓解者8例(17.8%);一周后疼痛完全缓解39例(86.8%),明显缓解5例.经治疗后6个月、12个月随访观察,有效率分别为 97.8%,97.8%.并发症少而轻微.[结论]螺旋CT引导下经皮穿刺卵圆孔注射阿霉素联合无水酒精毁损疗法对三叉神经痛具有定位准确,无痛苦,操作简单、安全,并发症少的优点,具有临床推广应用价值.  相似文献   

2.
目的:探讨在CT的定位引导下经皮穿刺三叉神经半月节,用药物毁损性阻滞治疗三叉神经痛的效果。方法:纳入首都医科大学宣武医院疼痛诊疗中心1994-03/2001—12采用CT引导下经皮穿刺三叉神经半月节毁损治疗的76例三叉神经痛患者。治疗前CT冠状及轴位扫描卵圆孔,除外继发性三叉神经痛。在穿刺卵圆孔过程中CT引导穿刺的方向并确认针尖的位置,经造影确保穿刺针准确位于神经节内,然后向三叉神经半月节注射神经阻滞破坏药阿霉素。在治疗后当日、治疗后第7天、第6个月和第12个月记录目测类比疼痛评分,生活质量评分和并发症。①目测类比疼痛评分:0分为无痛,10分为剧痛,1~3分为轻度疼痛,4-6分为中度疼痛,7~10分为重度疼痛。②疼痛缓解度:采用0-4数字疼痛缓解分级标准,0度:未缓解(疼痛未减轻);1度:轻度缓解(疼痛减轻约1/4);2度:中度缓解(疼痛减轻约1/2):3度:明显缓解(疼痛减轻约3/4以上);4度:完全缓解(疼痛消失)。③生活质量评分:就疼痛对食欲、睡眠、日常生活、精神状态、情绪、与人交往、生活兴趣等的干扰进行自我评价,以0~10分表示,0分为无干扰,10分为最严重干扰。结果:按实际处理分析,76例CT引导下经皮穿刺卵圆孔毁损疗法治疗三叉神经痛,除1例解剖变异未穿刺成功,其余病例均顺利完成穿刺和治疗。①治疗前后目测类比疼痛评分:治疗后低于治疗前[治疗前(8.7&;#177;2.7)分,治疗后第7天(1.6&;#177;2.1)分,治疗后6个月(2.1&;#177;0.9)分,治疗后12个月(2.3&;#177;0.7)分,P〈0.01]。②治疗后疼痛缓解情况:治疗后1周内疼痛完全缓解61例,不同程度减轻11例,无变化4例,其中2例改为神经外科手术治疗。治疗后12个月,完全缓解58例,11例未缓解。③治疗后生活质量评分:食欲、睡眠、日常生活、与人交往、生活兴趣治疗后第7天、6个月、12个月均低于治疗前[治疗前:(5.7&;#177;2.8),(4.0&;#177;2.0),(6.1&;#177;2.4),(6.1&;#177;2.4),(6.9&;#177;2.3)分;治疗后第7天:(2.5&;#177;1.5),(2.8&;#177;1.2),(3.5&;#177;2.3),(2.6&;#177;1.6),(4.8&;#177;2.3)分;治疗后6个月:(2.9&;#177;1.3),(2.0&;#177;0.7),(2.5&;#177;1.2),(3.1&;#177;1.5),(2.4&;#177;1.1)分;治疗后12个月:(2.2&;#177;1.1),(1.8&;#177;1.1),(2.3&;#177;1.6),(2.1&;#177;0.9),(1.8&;#177;1.0)分,P〈0.05或0.01]。结论:CT引导下经皮半月神经节毁损术对三叉神经痛效果明显。在CT引导下穿刺半月神经节,可使定位更准确,获得更好疗效。由于在局麻下操作,患者痛苦小,也可避免严重的并发症。  相似文献   

3.
三维CT引导下经皮射频热凝术治疗三叉神经痛   总被引:3,自引:1,他引:3  
目的评价三维CT引导下经皮卵圆孔穿刺用于治疗三叉神经痛的有效性和安全性。方法40例中、重度三叉神经痛患者,在Hartel前入路穿刺过程中,穿刺针抵达卵圆孔、触及骨质或穿刺深度达6~7cm时停止穿刺,行CT扫描和三维重建,在重建影像的指导下穿刺。结果所有穿刺均成功,疼痛缓解程度和有效率随时间增加,近期治疗有效率为95.00%,无严重并发症。结论在三维CT引导下行经皮卵圆孔穿刺,结合电刺激,可有效提高穿刺和定位效果。  相似文献   

4.
目的:探讨在CT的定位引导下经皮穿刺三叉神经半月节,用药物毁损性阻滞治疗三叉神经痛的效果。方法:纳入首都医科大学宣武医院疼痛诊疗中心1994-03/2001-12采用CT引导下经皮穿刺三叉神经半月节毁损治疗的76例三叉神经痛患者。治疗前CT冠状及轴位扫描卵圆孔,除外继发性三叉神经痛。在穿刺卵圆孔过程中CT引导穿刺的方向并确认针尖的位置,经造影确保穿刺针准确位于神经节内,然后向三叉神经半月节注射神经阻滞破坏药阿霉素。在治疗后当日、治疗后第7天、第6个月和第12个月记录目测类比疼痛评分,生活质量评分和并发症。①目测类比疼痛评分:0分为无痛,10分为剧痛,1~3分为轻度疼痛,4~6分为中度疼痛,7~10分为重度疼痛。②疼痛缓解度:采用0~4数字疼痛缓解分级标准,0度:未缓解(疼痛未减轻);1度:轻度缓解(疼痛减轻约1/4);2度:中度缓解(疼痛减轻约1/2);3度:明显缓解(疼痛减轻约3/4以上);4度:完全缓解(疼痛消失)。③生活质量评分:就疼痛对食欲、睡眠、日常生活、精神状态、情绪、与人交往、生活兴趣等的干扰进行自我评价,以0~10分表示,0分为无干扰,10分为最严重干扰。结果:按实际处理分析,76例CT引导下经皮穿刺卵圆孔毁损疗法治疗三叉神经痛,除1例解剖变异未穿刺成功,其余病例均顺利完成穿刺和治疗。①治疗前后目测类比疼痛评分:治疗后低于治疗前[治疗前(8.7±2.7)分,治疗后第7天(1.6±2.1)分,治疗后6个月(2.1±0.9)分,治疗后12个月(2.3±0.7)分,P<0.01]。②治疗后疼痛缓解情况:治疗后1周内疼痛完全缓解61例,不同程度减轻11例,无变化4例,其中2例改为神经外科手术治疗。治疗后12个月,完全缓解58例,11例未缓解。③治疗后生活质量评分:食欲、睡眠、日常生活、与人交往、生活兴趣治疗后第7天、6个月、12个月均低于治疗前[治疗前:(5.7±2.8),(4.0±2.0),(6.1±2.4),(6.1±2.4),(6.9±2.3)分;治疗后第7天:(2.5±1.5),(2.8±1.2),(3.5±2.3),(2.6±1.6),(4.8±2.3)分;治疗后6个月:(2.9±1.3),(2.0±0.7),(2.5±1.2),(3.1±1.5),(2.4±1.1)分;治疗后12个月:(2.2±1.1),(1.8±1.1),(2.3±1.6),(2.1±0.9),(1.8±1.0)分,P<0.05或0.01]。结论:CT引导下经皮半月神经节毁损术对三叉神经痛效果明显。在CT引导下穿刺半月神经节,可使定位更准确,获得更好疗效。由于在局麻下操作,患者痛苦小,也可避免严重的并发症。  相似文献   

5.
CT引导下经皮穿刺活检在肌骨病变中的诊断价值   总被引:6,自引:0,他引:6  
目的:评价CT引导下经皮穿刺活检在骨骼肌肉系统病变中的诊断价值。方法:在CT引导下经皮穿刺活检骨骼肌肉系统病变319例。结果:273例获得病理诊断,占85.6%(273/319),29例穿刺取得的病理组织不足,占9.1%(29/319),17例穿刺活检不成功,占5.3%(17/319)。257例具手术病理结果的病例中,212例穿刺结果和手术结果相符,45例不相符,其组织学定性的准确率为82.5%(212/257)。结论:CT引导下经皮穿刺活检是骨骼肌肉系统病变有效的诊断方法,可以使大多数患者避免切开活检;诊断的准确性和病变的组织学类型有关,少见病和取材的局限性是病理确诊困难甚至误诊的主要原因,而囊性和硬化性病灶是活检失败的主要原因。  相似文献   

6.
CT引导下经皮穿刺肺部小病灶活检技术的应用   总被引:6,自引:0,他引:6  
目的:探讨肺部小病灶CT引导下经皮穿刺活检技术的临床应用价值。材料和方法:运用半自动活检针对35例患者肺部小于3cm小病灶的CT穿刺活检结果与手术病理或临床随访情况对照,进行回顾性分析。结果:35例患者共40个小病灶,其中22例为肺癌,6例为肺结核,7例为炎性结节,活检对恶性病变的检出率为84%,无假阳性。结核患者活检诊断准确率为80%。并发症的发生率为31.4%。结论:肺部小病灶的CT引导下经皮穿刺活检准确性较高,穿刺技术中较关键的因素是训练患者的呼吸配合以及操作者的熟练程度。  相似文献   

7.
CT引导下经皮穿刺肝囊肿及肾囊肿硬化剂治疗的疗效分析   总被引:1,自引:0,他引:1  
目的探讨CT引导下经皮肝囊肿、肾囊肿硬化剂治疗的临床应用价值。方法51例(肝脏囊肿20例,肾脏囊肿31例)经CT扫描确诊为单纯性囊肿的患者,囊肿大小自2.8cm&#215;3.5cm&#215;5.3cm~9.8cm&#215;15.6cm&#215;16.8cm不等。在CT导向下应用穿刺抽吸针抽出囊液,并注射硬化剂无水乙醇治疗,硬化剂注射量约为抽出囊液的25%。术后分别于3个月及半年后各复查一次CT扫描。结果51例肝脏囊肿及肾脏囊肿均一次穿刺成功,有效率为100%。半年后复查见49例完全消失或明显缩小,2例有缓慢复发迹象。51例中,46例于术后3个月复查一次,且中33例于术后半年复查第二次,另外5例于半年后复查1次,均未见复发。结论CT引导下经皮肝囊肿及/或肾囊肿硬化剂治疗有较高临床应用价值,且方便、安全有效。  相似文献   

8.
CT引导下经皮穿刺椎体成形术   总被引:1,自引:0,他引:1       下载免费PDF全文
目的 探讨和评价CT引导下完成经皮穿刺椎体成形术的方法和疗效。方法 回顾分析在CT引导下采用经皮穿刺椎体成形术治疗脊柱转移瘤、血管瘤及骨质疏松压缩骨折等183例241个椎体操作经验,并与其他文献对比。结果 操作全部按计划完成,准确率100%,无失败和损伤,达到了预期的临床治疗效果。结论 CT引导下椎体成形术操作简便、准确、痛苦小,疗效佳,为应用前景广泛的非血管介入治疗。  相似文献   

9.
目的 探讨CT联合实时超声引导穿刺活检胸膜或胸膜下结节(SPPN)的可行性。方法 回顾性分析接受经皮穿活检的38例SPPN患者,其中17例接受CT联合超声引导下活检(CT+US组),21例接受单纯CT引导活检(CT组),比较2组穿刺活检手术时间、占机时间、CT引导次数、有效辐射剂量及术后并发症。结果 CT+US组CT引导次数、手术时间、占机时间、有效辐射剂量和总剂量均低于CT组(P均<0.01),2组术后发生气胸、出血差异均无统计学意义(P均>0.05)。结论 CT联合实时超声引导穿刺活检SPPN可降低穿刺技术难度,缩短手术时间,减少辐射剂量。  相似文献   

10.
目的分析CT引导下,对卵巢囊肿穿刺抽吸、无水乙醇反复冲洗硬化治疗的临床疗效。方法对63例卵巢囊肿,71个囊腔超声引导下穿刺抽尽囊液,用与抽出囊液25%量的无水乙醇反复冲洗1~4次硬化治疗。结果 71个囊腔均穿刺硬化治疗成功,有效率100%。结论 CT引导介入治疗卵巢囊肿操作微创、安全、经济、治愈率高,可以取得较手术治疗更好的疗效,值得妇科临床应用。  相似文献   

11.
A patient with trigeminal neuralgia may need different forms of treatment during his or her lifetime. Physicians should be aware of the different available surgical treatments, and know their effectiveness, side effects and complications. Microvascular decompression is considered by many to be the most effective treatment. The goal of the procedure is to remove the cause of pain, obtained by decompressing the nerve at its entry point into the pons. Percutaneous procedures are more easily performed but the recurrence rate of pain is higher. It is difficult to compare the results of surgical procedures reported by different authors. Therefore, we compare the efficacy of 155 microvascular decompressions with 113 radiofrequency thermocoagulations and 215 percutaneous microcompressions performed by the same surgical team. Our study confirms microvascular decompression as the most effective surgical treatment, although percutaneous procedures play an important role in the treatment protocol and have to be offered to patients as a therapeutic option. Received: 22 August 2000 / Accepted in revised form: 22 January 2001  相似文献   

12.
The aim of this study was to define criteria for the selection of patients for percutaneous or open operations for the cure of drug-resistant trigeminal neuralgia (TN). Trigeminal percutaneous radiofrequency thermorhizotomy (TPRT) has an established place because of its safety in elderly patients, while microvascular decompression (MVD) has appeal in younger patients beause of its non-destructive nature and because it attacks what is believed to be the primary etiology of tic douloureux. Nevertheless, MVD is a successful operation only when true neurovascular conflict (NVC) is ascertained, rather than a simple arterial loop and neurovascular contract. Probably, many immediate failures and early relapses are the consequence of the inadequate patient selection for MVD on the presumption that this operation is in any case the ideal cure. The inadequate selection can be explained by the difficult preoperative diagnosis of NVC in the past. Indeed, angiography and computed tomography showed the neurovascular contact but not the size of compression. Fortunately, today magnetic resonance imaging is a reliable instrument to ascertain NVC. So, the diatribe between the supporters of percutaneous techniques and MVD can be concluded with the following: (1) percutaenous techniques are indicated for patients without demonstrated NVC (including patients with TN in multiple sclerosis) and in those with NVC if MVD is contraindicated by ill-health or refused by the informed patient; and (2) MVD is incated for patients with ascertained NVC who are in good health and who, informed of the surgical risk, favor this operation desiring no sensory deficit. Received: 23 June 2001 / Accepted in revised form: 24 August 2001  相似文献   

13.
目的观察卡马西平联合多虑平在特发性三叉神经痛治疗中的疗效和不良反应。方法卡马西平联合多虑平(治疗)组60例,卡马西乎(对照)组60例,均诊断为特发性三叉神经痛,用视觉模拟评分法给疼痛评分,通过治疗后1周、2周、1月、3月视觉模拟评分判断疗效。结果治疗组疗效明显高于对照组,治疗组患者疼痛积分(分别为5.3±1.82,1.8±1.79,1.6±0.96,0.62±0.94)显著低于对照组(6.1±1.74,4.5±1.27,3.36±1.22,2.7±1.14)(P〈0.05),卡马西平用量、不良反应发生率和程度均较对照组低。结论两种方法对特发性三叉神经痛均有效,但治疗组疗效更好,且不良反应发生率低,更安全。  相似文献   

14.
New insight into trigeminal neuralgia   总被引:2,自引:0,他引:2  
Trigeminal neuralgia is universally considered the neuropathic facial pain most and best known in medical practice. We propose a short review on trigeminal neuralgia reporting its main clinical aspects, unsolved problems and highlighting differential diagnosis between classical and symptomatic trigeminal neuralgia.  相似文献   

15.

Objective

After medication failure, patients with refractory trigeminal neuralgia (TGN) often present urgently and seek more potent or invasive therapies such as opioids or surgical options. Peripheral nerve blocks, safe and simple, may offer extended pain relief prior to opioid use or more invasive ganglion level procedures.

Methods

We report a retrospective case-series (urgent care, at a large urban medical center, over a 2?year period) of nine patients with intractable primary TGN who underwent peripheral trigeminal nerve blocks after failing conservative medical therapy. After antiseptic skin preparation, a 30?g needle was inserted localizing to the supraorbital, infraorbital, and mental foramens. 0.5?mL of 0.25% bupivicaine:1% lidocaine was injected locally at all three foramens. Then, 1?mL of the above was injected in the region of the auriculotemporal nerve (see Video 1). All injections were done on the side with TGN pain.

Results

All nine patients experienced immediate pain relief of >50% with 7 of 9 being completely pain free or just mild paresthesia. Six of nine patients had lasting pain relief (1–8?months); three patients reporting pain now tolerable with adjunct medication and two patients were completely pain free.

Conclusions

The treatment paradigm for TGN remains unclear when a patient fails conservative medical therapy. In this case series, many patients achieved rapid and sustained TGN pain relief with peripheral trigeminal nerve blocks. This modality should be considered as a potential therapeutic option in the ED or urgent care setting.  相似文献   

16.
目的 探讨射频热凝术治疗老年人三叉神经痛的穿刺方法,射频温度与时间,治疗的并发症。方法 采用Hartel前入路穿刺法,射频热凝术治疗三叉神经痛。结果 本组620例。总有效率91.3%。无死亡率。并发症少,轻,7年随访复发率21.8%。结论 射频热凝术是治疗老年人三叉神经痛安全。简便,有效,适应症广,并发症少,轻的方法。  相似文献   

17.
目的 探讨3.0T MRI在血管压迫性三叉神经痛中的应用。方法 对32例三叉神经痛患者行轴位3D-TOF MRA及3D-FIESTA-C,并分别进行MPR、CMPR及仿真内镜重建(MRVE),分析患侧血管与神经的关系。结果 32例中,5例(5/32,15.63%)患侧血管与神经无接触,4例(4/32,12.50%)可疑接触,5例(5/32,15.63%)明确接触;18例(18/32,56.25%)存在压迫,其中14例(14/18,77.78%)责任血管为小脑上动脉,2例(2/18,11.11%)为岩静脉,另外分别为小脑前下动脉、基底动脉各1例(1/18,5.56%)。对其中15例行微血管减压术(MVD),MRI所示责任血管与术中所见相吻合;术后11例疼痛消失,4例疼痛较前明显减轻。结论 3.0T MRI可有效区分导致血管压迫性三叉神经痛的责任动脉及静脉与神经的关系;3D-FIESTA-C的CMPR及MRVE可提高判断接触与压迫的敏感度与准确率,对显示责任静脉具有优势,MRVE三维空间立体定位可作为MVD术前评估的有力补充。  相似文献   

18.
目的探讨内窥镜下,桥脑小脑角三叉神经微血管减压及神经梳理手术的围手术期护理干预对病人的影响。方法对1999~2005年34例单侧原发性三叉神经痛患者按入院顺序随机分为两组,1999~2003年的17例为对照组;2004~2005年的17例为干预组,对照组采用常规治疗护理,干预组除常规治疗护理外,还制定了系统的护理干预措施,对病人进行个性化护理。结果两组病人在住院时间和手术并发症等方面差异都有极显著意义(P<0.01)。结论系统的护理干预,对防治病人术后并发症有积极的意义。  相似文献   

19.
目的探讨三叉神经周围支撕脱术治疗三叉神经痛的近期疗效。方法对23例确诊为原发性三叉神经痛者,施行神经撕脱术。第一支1例,第二支11例,第三支11例。结果本组23例,22例有效,1例无效。8例在术后10d有一过性跳疼。术后半年至8年复发的6例中,第二支2例,第三支4例,其中3例又再次手术。结论三叉神经痛周围支撕脱术治疗三叉神经痛近期疗效好,远期疗效还待进一步观察。  相似文献   

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