腹部离心性脂肪营养不良1例

报告腹部离心性脂肪营养不良1例。患儿女,10岁,右下腹、外阴萎缩5年,无明显自觉症状。皮肤科情况：右下腹、右侧会阴、阴唇部可见境界清楚的萎缩性斑片,萎缩凹陷区皮下血管清晰可见。皮损组织病理示：表皮轻度萎缩,真皮胶原纤维减少,真皮血管扩张充血,浅层血管周围稀疏淋巴组织细胞浸润,皮下脂肪层、脂肪细胞呈团块状,少许坏死。     

腹部离心性脂肪营养不良2例

1 临床资料 例1.女,9岁.因腹股沟皮损3年,加重1年,于2008年3月5 日来我院就诊.患儿6岁时发现左侧腹股沟有一钱币大蓝紫色斑,境界清楚.1年后蓝紫色斑变浅.     

婴儿腹部离心性脂肪营养不良1例

婴儿腹部离心性脂肪营养不良是一种特殊类型的皮肤与皮下脂肪萎缩。Imamura（1970）报告5例，均为日本儿童。Lee（1982）报告8例，均为朝鲜儿童。张红(1989）报告3例其后陆续有病例报告，现将我们所见1例报道如下。     

婴儿腹部离心性脂肪营养不良1例

患儿女,5岁。出生时即发现患儿双侧髋部对称性钱币状淡蓝色斑,境界清楚,4岁时皮损离心性扩大,融合成暗红色萎缩斑。检查见腰骶部皮下脂肪萎缩。诊断为婴儿腹部离心性脂肪营养不良。     

兄弟二人同患幼儿腹部离心性脂肪营养不良

患儿男,10岁.因腹股沟和腹部皮肤离心性凹陷性萎缩斑3年余就诊.患儿于3年前无明显原因出现左侧腹股沟皮肤浅红斑及凹陷,无全身及局部自觉症状,此后凹陷区域逐渐呈离心性向腹部扩大.发病以来,智力和身体其他部位发育正常.患儿胞弟,8岁,于1年前也出现类似皮损.     

兄弟二人同患幼儿腹部离心性脂肪营养不良

患儿男,10岁.因腹股沟和腹部皮肤离心性凹陷性萎缩斑3年余就诊.患儿于3年前无明显原因出现左侧腹股沟皮肤浅红斑及凹陷,无全身及局部自觉症状,此后凹陷区域逐渐呈离心性向腹部扩大.发病以来,智力和身体其他部位发育正常.患儿胞弟,8岁,于1年前也出现类似皮损.     

兄弟二人同患幼儿腹部离心性脂肪营养不良

患儿男,10岁.因腹股沟和腹部皮肤离心性凹陷性萎缩斑3年余就诊.患儿于3年前无明显原因出现左侧腹股沟皮肤浅红斑及凹陷,无全身及局部自觉症状,此后凹陷区域逐渐呈离心性向腹部扩大.发病以来,智力和身体其他部位发育正常.患儿胞弟,8岁,于1年前也出现类似皮损.     

幼儿腹部远心性脂肪营养不良三例

幼儿腹部远心性脂肪营养不良(Lipod-ystrophia Centrifugalis Abdominalis Juve-nilis)是近十多年提出的少见病,现报告3例如下.     

兄弟同患婴幼儿腹部离心性脂肪营养不良2例

婴幼儿腹部离心性脂肪营养不良是一种特殊类型的皮肤和皮下脂肪萎缩,本病临床并不常见,同胞兄弟共患此病更为少见.我们诊治同胞兄弟2人均在5岁左右患婴幼儿腹部离心性脂肪营养不良,现报告如下.     

兄弟二人同患幼儿腹部离心性脂肪营养不良

患儿男,10岁.因腹股沟和腹部皮肤离心性凹陷性萎缩斑3年余就诊.患儿于3年前无明显原因出现左侧腹股沟皮肤浅红斑及凹陷,无全身及局部自觉症状,此后凹陷区域逐渐呈离心性向腹部扩大.发病以来,智力和身体其他部位发育正常.患儿胞弟,8岁,于1年前也出现类似皮损.     

Lipodystrophia centrifugalis abdominalis infantilis

We describe the first case of lipodystrophia centrifugalis abdominalis infantilis to occur outside Japan. A 7-year-old Chinese boy presented with the classical features, which include the early onset of localized depression of the skin of the abdomen, centrifugal progression of the skin lesion and an erythematous scaling advancing edge. The subcutaneous fat is decreased in the depressed areas.     

婴儿腹部远心性脂肪萎缩症

本文综述了婴儿腹部远心性脂肪萎缩症的病因、病理、症状、治疗与预后。     

Lipodystrophia centrifugalis abdominalis infantilis: report of four cases

Lipodystrophia centrifugalis abdominalis infantilis (LCAI) is a rare lipodystrophic disorder mainly affecting Eastern Asian children. We report the clinicopathologic findings of four Taiwanese children with LCAI in which local induration or ecchymotic changes preceded the skin depressions on the groin or abdomen.     

Lipodystrophia centrifugalis abdominalis infantilis: statistical analysis of 168 cases

Lipodystrophia centrifugalis abdominalis infantilis is a localized lipodystrophic disease affecting young children. A total of 168 cases were collected from dermatology literature. Where possible, details of the data were also obtained from the authors. Most of the patients were Japanese, Korean, or Chinese in origin. The Caucasian patients were from England, Italy, France, Germany, Spain, and the United States. The male-to-female ratio was 1:1.6. The depressed lesions developed during the first 4 years of life in the groin or axilla, surrounded by a slight erythematous change. Histologically, subcutaneous fatty tissue was lost or markedly decreased in the depressed areas, and marked or moderate mononuclear cell infiltration was observed in the fatty tissue of the surrounding erythematous area. The depressed lesions extended centrifugally to involve the abdominal or chest walls. However, in most cases, such enlargement spontaneously ceased by the age of 13 years. No drugs used were effective in preventing the enlargement of depressed lesions, but more than 60% of patients showed spontaneous improvement after the cessation of enlargement. Lipodystrophia centrifugalis abdominalis infantilis is a clinically and histologically distinct lipodystrophic disease affecting young children, mostly in Asian countries, but a few in Western countries.