Melanocytes of a melanocytic nevus in a lymph node from a patient with a primary cutaneous melanoma associated with a small congenital nevus

Aggregates of melanocytes within the parenchyma of a supraomohyoid lymph node were found in a lymph node dissection from a 52-year-old woman who had a primary cutaneous melanoma that had arisen in association with a small congenital nevus. The melanocytes in the lymph node were interpreted to be those of a benign melanocytic nevus, and not those of malignant melanoma, based on similarities in morphologic features and immunohistochemical staining between the melanocytes in the node and those in the cutaneous congenital nevus.     

Paraneoplastic pemphigus in a patient with a thymoma

A 76-year-old woman, with a history of thymoma, presented with a painful extensive stomatitis, painful paronychia, lichenoid papules on the hands and superficial erosions on the neck and the trunk. Histological examination showed lichenoid changes, acantholytic blister formation and apoptotic keratinocytes. Direct immunofluorescence was positive for IgG both in the epidermal intercellular spaces and along the basement membrane zone. Indirect immunofluorescence was similarly positive in a pemphigus vulgaris pattern. There was only a partial response to intravenous corticoids. These findings allowed the diagnosis of paraneoplastic pemphigus. The diagnostic characteristics, histopathology and the differential diagnosis of this disease are discussed.     

Histopatología de la uña

The structure of the nail unit is complex and many dermatologists and dermatopathologists have an incomplete understanding of it. Familiarity with the anatomy and histology of this unit, however, is a key factor in improving the diagnostic yield of nail biopsy. Inflammatory or infectious conditions that affect the nail can have a marked impact on a patient's quality of life. A wide-ranging variety of tumors can also develop in this region and they may be life-threatening or require surgery that will result in functional defects. The author reviews the anatomy and histology of the nail unit as well as the basic histopathologic findings in the most common conditions affecting the nails.     

When is a chrysanthemum dermatitis not a chrysanthemum dermatitis not a chrysanthemum dermatitis?

In order to provide a new reference point in the dermatological literature from which the naming of florists' chrysanthemums may be regularised and standardised, the case is presented for the use of the generic name Dendranthema together with a cultivar name in place of a specific epithet. A review of cultivar specificity in chrysanthemum dermatitis is also presented.     

When a postsurgical dehiscence becomes a serious problem

Therapeutic management of nonhealing wounds is often a challenging condition. Postlaparotomy wound dehiscence can become a serious problem in patients affected with chronic pain and abdomen distension. In this case report, negative-pressure wound therapy with the Chariker-Jeter method was used to treat a dehiscence in a patient affected with type I spinocerebellar ataxia.     

Eyebrow threading: a boon or a bane

Eyebrow threading is a practice of shaping the eyebrows. Many dermatological complications have been briefly mentioned in various publications. There are scant data regarding the appearance of molluscum in the line of eyebrows after a session of threading. We report a series of eight patients both males (3) and females (5) who had lesions of molluscum in the eyebrow region after threading. The earlier reported cases are only among the females. The present study is highlighting the appearance of molluscum in the region of eyebrow after a session of threading from beauty salon. So, to the best of our knowledge, this is the first report of its kind describing same pathology in males. The rational of reporting this case series is to create awareness among the dermatologists as well as in general population about potential hazards of threading.     

幼儿疥疮一例

患儿,男,3岁。臀部皮疹伴痒2个月余。皮肤科情况:臀部、双下肢、躯干可见红斑、丘疹、结节;阴茎可见单发暗红色结节。皮肤镜示:镜下可见隧道,隧道一端可见棕色小三角形结构。反射式共聚焦显微镜示:镜下可见开口于表皮的中高折光隧道结构;境界清楚疥螨虫体;椭圆形,轮廓清楚的虫卵结构;圆形高折光粪便结构。诊断:疥疮。     

Incorporating a medical spa into a physician-run practice

The age-old spa concept is no less valuable today than it was during the time of Julius Caesar. Over the centuries, there have been many iterations of the concept of the spa. The most recent is the medical spa, which has become the fastest-growing segment of the spa industry. Many physicians including dermatologists wish to incorporate a medical spa into their practices. This article discusses the key elements that should be considered to make this venture successful.     

Atopic dermatitis as a term and a disease

Basing on the literature data and their own clinical experience, the authors consider atopic dermatitis as skin manifestations of hereditary atopic constitution. They distinguish 5 clinical forms of the condition, emphasizing the age succession (phase pattern) of the clinical and morphologic picture of the dermatosis. Attention is called to the fact that atopic dermatitis may be a part of the clinical picture of many syndromes. The authors hope that the present discussion will minimize the confusion in the terminology of this disease.