共查询到19条相似文献,搜索用时 48 毫秒
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林红 《岭南现代临床外科》1999,(2)
为探讨乳腺癌的早期诊断,总结我院自1994~1997年间70例乳腺癌的诊断经验。结果 Ⅰ期乳腺40例,占57.4%,其中小乳腺癌13例占18.6%,0期原位癌3例,占4.3%,50岁以下乳腺癌占70%。认为重视乳腺癌的高危因素、定期检查和乳腺X线摄片是早期诊断乳腺癌的重要措施。 相似文献
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陈佩珍 《中国普外基础与临床杂志》1996,(2)
乳腺癌的早期诊断陈佩珍虽然我国乳腺癌的发病率低于西方国家,但近年津、京、沪三大城市的统计资料已显示我国的乳腺癌发病率在逐年递增[1],同时还出现发病年龄年轻化的倾向。在就诊患者中90%是自己偶尔发现异常。在绝大部分地区没有开展专业性普查,因此在确诊病... 相似文献
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近年来,乳腺癌的发病率有上升的趋势,据报道在一些国家和地区乳腺癌在女性恶性肿瘤的发病率已上升到首位。因些,乳腺癌是危害妇女健康的主要肿瘤,而乳腺癌的早期诊断是决定乳腺癌预后的关键。本文重点讨论早期乳腺癌的诊断。 诊断早期乳腺癌的重要意义 乳腺癌具有好发血行转移的生物学特性,其发生率之高和造成后果的严重性,已经引起人们普遍重视。临床实践表明,初诊乳腺癌患者中约半数以上已经发生血行转移,而这些微小的转移癌灶,虽然潜在于体内,但用目前的检查方法尚难查出。李树玲报道Ⅰ期乳腺癌虽经根治性手术切除, 相似文献
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目的:探讨早期乳腺癌的临床特点及诊断方法,为提高早期乳腺癌的诊断率提供参考依据.方法:回顾性分析78例早期乳腺癌的临床资料,术前均行超声、钼靶x线、超声定位穿刺活检.结果:78例病人中乳腺腺体局限性增厚47例(60.3%),可触及结节者仅29例(37.2%);无任何体征者2人(2.5%).超声联合钼靶x线及超声定位穿刺活检对早期乳腺癌的诊断符合率分别为91.02%,92.30%,与单纯超声及钼靶x线检查相比有显著性差别.结论:高危年龄妇女乳腺增生伴症状加重、乳腺局限性增厚是早期乳腺癌的重要表现;及时对乳腺结节、局限性增厚、钼靶x线致密影等可疑病灶行组织学穿刺活检或超声联合钼靶检测可提高早期乳腺癌的诊断率. 相似文献
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乳腺癌癌前病变的病理诊断 总被引:2,自引:0,他引:2
傅西林 《中国实用外科杂志》2000,20(5)
1 乳腺癌癌前病变的概念 乳腺癌是乳腺上皮细胞增生及不典型增生的基础上逐步发展而成的。一般把某些在组织形态学有一定程度异型或增生活跃 ,经随访有一部分发展成癌的乳腺增生性病变称为乳腺癌癌前病变。正确认识乳腺癌的癌前病变 ,对于早期发现、早期诊断乳腺癌和做好二级预防工作均有重要的现实意义。但迄今为止 ,有关乳腺癌癌前病变的具体内容尚未完全统一 ,究其原因主要是由于不同学者在研究观察方法、诊断标准及随访时间不同所致。目前多数意见认为不典型导管上皮增生、不典型小叶增生及乳头状瘤病应视为乳腺癌的癌前病变[1] 。… 相似文献
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BACKGROUND: The current study sought to determine effective methods for disclosing breast cancer diagnosis and to identify epidemiologic patterns in patient preference for method of information disclosure. METHODS: Surveys were sent to 691 breast cancer patients over 10 years. Questions evaluated the best methods for telling a woman of her diagnosis. The chi-square, Wilcoxon rank, and Mantel-Haenszel tests were used for statistical associations. RESULTS: Ninety percent of patients had no preference for which gender disclosed the diagnosis. Fifty-nine percent said they believe it is important to be asked how much information one would like to know when initially told the diagnosis. However, most (54%) were not asked when they were told. When asked if previous ideas about breast cancer influenced their concerns, 79% answered "yes" or "somewhat." However, only 10% knew "a great deal." CONCLUSIONS: Patients have defined preferences about breast cancer diagnosis disclosure, making effective methods of diagnosis disclosure important to identify and practice. 相似文献
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���ٰ��Ļ������� 总被引:2,自引:0,他引:2
乳腺癌的基因治疗是继手术、放疗、化疗和内分泌治疗之后发展的一种新的治疗手段。近年来 ,由于对肿瘤分子病理学的认识、重组DNA技术的快速发展 ,针对肿瘤的基因治疗应用于临床已有可行性。目前对乳腺癌的基因治疗主要集中在免疫基因治疗、肿瘤抑癌基因治疗、凋亡基因治疗、化学基因治疗、基因敲除基因治疗和抗血管生成基因治疗。1 免疫基因治疗免疫基因治疗是从基因水平通过调动宿主的免疫系统来识别并破坏癌细胞。 90多年前 ,人们已经认识到肿瘤细胞可以呈现一定程度的免疫原性。肿瘤免疫治疗的策略是诱发或加强宿主体内针对肿瘤细胞… 相似文献
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J W Bradbeer 《The British journal of surgery》1985,72(11):927-928
A method of diagnosis of the solid discrete breast lump using frozen section examination of a Tru-cut needle biopsy is described. In 194 patients, the Tru-cut biopsy report is compared to the histological report of the excised lesion. Overall accuracy is 90 per cent, sensitivity 89 per cent, specificity 96 per cent, predictive value of a positive report 99 per cent, and predictive value of a negative report 56 per cent. The advantage of the technique is that many patients with breast cancer can be informed of the diagnosis at their first attendance. 相似文献
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目的:探讨核磁共振(MRI)在乳腺癌诊断中的临床应用价值。方法:对45例乳腺肿物患者进行乳腺MRI检查,分析影像学表现,并对其中17例患者进行病变的增强扫描,对增强扫描曲线作出评价。结果:45例患者经术后病理证实:乳腺癌24例,乳腺良性病变21例,MRI对乳腺癌的术产诊断与病理符合率为96%(23/24),假阳性率为2%(1/45)。结论:乳腺MRI作为一种新的检查方法,对乳腺癌诊断有较大的临床应用价值。 相似文献
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Tsuda H 《Nihon Geka Gakkai zasshi》2002,103(6):487-491
Alterations in protooncogenes and tumor-suppressor genes at the DNA and/or protein level indicate the biological properties of individual breast cancers. Information on these genetic and protein alterations is considered to be useful diagnostically and these alterations are now being applied in routine diagnosis or are under investigation for diagnostic application in the areas of: 1) determination of indications for specific therapies for advanced or metastatic breast cancers; 2) prediction of the response of primary tumors to adjuvant or neoadjuvant systemic therapies; and 3) identification of patient groups at high or low risk of recurrence from node-negative breast cancer. 相似文献