纯巨核细胞再生障碍(附一例报告)

纯巨核细胞再生障碍的特点是骨髓选择性巨核细胞减少，外周血血小板减少不是破坏加速，而是生成不足所致，巨核细胞及血小板不仅有数量的减少，而且有形态的改变．对发病机理、诊断标准、治疗及转归进行了讨论。     

纯巨核细胞再生障碍（附一例报告）

纯巨核细胞再生障碍的特点是骨髓选择性巨核细胞减少，外周血血小板减少不是破坏加速，而是生成不足所致，巨核细胞及血小板不仅有数量的减少，而且有形态的改变，对发病机理、该断标准、治疗及转归进行了讨论。     

Pure white cell aplasia and health food products.

The safety of ''health'' foods and complementary medicine products is increasingly questioned. We report a case of pure white cell aplasia developing in a patient who took a variety of such products leading to an excessive intake of zinc. Recovery was complete following the withdrawal of her ''medications''. The aetiology of the pure white cell aplasia is discussed with respect to the ingredients of the products ingested.     

Pure red cell aplasia caused by acute hepatitis a

Pure red cell aplasia is characterized as a normocytic anemia associated with reticulocytopenia and the absence of erythroblasts in the bone marrow. Pure red cell aplasia can be induced by various causes such as thymoma, connective tissue disease, viral infection, lymphoma, and adverse drug reactions. There have been only a few reports of pure red cell aplasia associated with acute viral hepatitis A. In Korea, no case of pure red cell aplasia caused by acute hepatitis A has yet been reported. We recently experienced a case of acute viral hepatitis A complicated by pure red cell aplasia. The patient was successfully treated with corticosteroids. Here we report this case and review the literature.     

尿红细胞平均容积和形态观察在单纯性血尿鉴别诊断中的应用

目的：探讨鉴别肾小球性与非肾小球性血尿的检验方法。方法：用血细胞计数仪检测尿中红细胞平均体积（ＭＣＶ）并结合显微镜红细胞形态观察。结果：肾小球性血尿：尿ＭＣＶ为６２．２±５．２ｆｌ,变形红细胞百分率４６．７±１２．０％;非肾小球性血尿：尿ＭＣＶ为８９．４±５．８ｆｌ,变形细胞百分率１０．０±５．０％,两者存在显著性差异（Ｐ＜０．０１）。尿ＭＣＶ结合尿红细胞形态观察,对肾小球性血尿诊断符合率为９５％（３８／４０）,非肾小球性血尿诊断符合率为９８％（４８／４９）。结论：用血细胞计数仪测定尿ＭＣＶ结合显微镜观察尿ＲＢＣ形态,对单纯性血尿的鉴别诊断颇有价值     

Pure red cell aplasia and thymoma associated with high levels of the suppressor/cytotoxic T lymphocyte subset

A 64 year old man admitted to hospital with increasing effort dyspnoea and lethargy was found to have a thymoma and pure red cell aplasia. Lymphocytes accounted for 20-30% of marrow cells, and numbers of T8 suppressor/cytotoxic cells in peripheral blood were greatly increased. He remained anaemic after removal of the thymoma despite blood transfusions, and immunosuppression with prednisolone 60 mg and cyclophosphamide 50 mg daily was started. The dose of prednisolone was reduced to 15 mg owing to steroid myopathy and the risk of opportunistic infection. He went into remission, and the dose was further decreased to 10 mg daily.     

Teratogenic effects of diphenylhydantoin.

A child aged 24 months had multiple congenital abnormalities and delayed development. The 28-year-old mother had been treated since childhood with anticonvulsants. Her previous pregnancies had resulted in three early spontaneous abortions and one child with severe bilateral cleft lip and palate. This case report further suggests a relationship between maternal diphenylhydantoin use and fetal anomalies.     

白细胞滤器对红细胞及血液流变学的影响

目的观察血液经白细胞滤器滤过处理（滤除血液白细胞）后红细胞血液流变学的变化,为临床安全输血提供实验数据。方法选择42例入库合格血液,应用白细胞过滤器去除白细胞,过滤前后分别进行血液流变学（全血高切黏度、中切黏度、低切黏度、全血还原黏度）检测。红细胞聚集指数、变形指数和刚性指数,红细胞电泳时间,游离Hb等红细胞相关参数的测定。结果经白细胞滤器处理后,红细胞各项指标均无明显改变,血液黏度轻度下降。结论用白细胞过滤器过滤去除血液中白细胞对红细胞、血液质量无明显影响。