Physico－chemical characterization of the S－ and R－ lipid A derived from the natural endotoxin（lipopolysaccharide） preparation

Ｐｈｙｓｉｃｏ－ｃｈｅｍｉｃａｌｃｈａｒａｃｔｅｒｉｚａｔｉｏｎｏｆｔｈｅＳ－ａｎｄＲ－ｌｉｐｉｄＡｄｅｒｉｖｅｄｆｒｏｍｔｈｅｎａｔｕｒａｌｅｎｄｏｔｏｘｉｎ（ｌｉｐｏｐｏｌｙｓａｃｃｈａｒｉｄｅ）ｐｒｅｐａｒａｔｉｏｎｓＪｉａｏＢｉｎｇｈｕａ；（...     

An Overview on the Progress of Chemical Constituents and Bioactivities of Plants in Urticaceae during 2000－2010

Urticaceae includes about 1300 species in 47 genera which largely spread in wet tropical regions, and 341 species in 25 genera are in China. Some species are used in Chinese folk medicine. So far, studies on chemistry and pharmacology of Urticaceous plants are mainly focused on nettle of Urtica L. In this review, the chemical researches on 35 new compounds and related pharmacological effects of the plants in Urticaceae reported during 2000－2010 are described. The 35 new compounds belong to the classes of lignan, secolignan, norlignan, flavonoid, alkaloid, sesquiterpenoid, triterpenoid, sterol, and sphingolipid. The main bioactivities include cytotoxic, antitumor, antimicrobial, antifungal, anti-BPH, anti-HIV, antidiabetic, hypolipidemic, 5α-reductase inhibitory, hair regrowth promotion, and anti-oxidative activities.     

Studies on the Chemical Constituents of the Roots of Rhododendron Molle G. Don

The compounds from the root of Rhododendron molle G. Don were isolated, purified by various chromatographic techniques, and their structures were identified according to the physical and chemical features and spectral data. Three compounds were separated from the root of Rhodo-dendron molle G. Don and identified as Rhodojaponin-Ⅲ, taraxerol, β-sitosterol for the first time.     

Dynamic Observation on the Effects of Different Suture Techniques on the Biomechanical Properties in the Healing of Tendons

Summary： To identify the best suture techniques for the tendon repair, the biomechanical properties of tendons sutured by different methods were dynamically examined. 140 chickens were divided into 2 groups equally： group A and group B. The tendon of the right side was subjected to injury-repair process, and the tendons of the left sides served as controls in both groups. In group A, ＂figure-of- 8＂ suture, modified Kessler suture and Bunnell suture were used for the 2nd to 4th paws respectively, while in group B, Kleinert suture, Tsuge suture and Ikuta suture were used. On the day 0, 3, 7, 14, 21, 28, 42 after operation, 10 animals were sacrificed and the flexor tendons of both sides were harvested for strength test. The results showed that the initial strength of the repaired tendons and the strength after 6 weeks following tendon cut were far below those of intact tendons, irrespective of suture techniques used. With the 6 techniques, the P of tendons repaired by Tsuge suture was increased continually, reaching the highest value on the 42nd day. The P of tendons sutured by the modified Kessler suture was slightly lower than that by Tsuge suture, but it was increased steadily in healing. The tendons repaired by figure-of-8 suture yielded the lowest P It was concluded that Tsuge suture and modified Kessler suture were the best techniques for tendon repair.     

Investigation on Etiology of Nasal Polyps

One hundred and seventy patients withnasal polyps were studied. According to thehistory, skin test with inhalent allergens,determination of serum, nasal secretion andpolyps fluid IgE, and X-ray films of nasalsinuses, it was suggested that 93.5% of themmight have complicated with allergic diseases,87.7% with sinusitis. There were 91 cases(53.5%) with a history of allergy, and 107     

Effects of Chemical Stimulation in the Periaqueductal Gray on Vocalization in the Squirrel Monkey

Twenty-nine agonists and 32 antagonists of more than 10 transmitters known to be present in the periaqueductal gray(PAG)have been injected into the squirrel monkey's PAG in order to test their effects on spontaneous vocalization at sites yielding vocalization with electrical stimulation. Vocalization could be elicited with the glutamate agonists sodium-L-glutamate,     

Portal Vein Embolization with Lipiodol for Treatment of HCC－An Experimental Study

（刘鹏程）（郭俊渊）（胡国栋）（王承缘）（黄植诚）（刘少春）ＰｏｒｔａｌＶｅｉｎＥｍｂｏｌｉｚａｔｉｏｎｗｉｔｈＬｉｐｉｏｄｏｌｆｏｒＴｒｅａｔｍｅｎｔｏｆＨＣＣ－ＡｎＥｘｐｅｒｉｍｅｎｔａｌＳｔｕｄｙ￥ＬＩＵＰｅｎｇ－ｃｈｅｎｇ；ＧＵＯＪｕｎ－ｙｕ...     

An Epidemiological Investigation on the Efficacy of Tubal Ligation in Henan Province

An analysis was made of the data from a retrospective epidemiological study of 8766 cases of tubaf tigation performed between 1978 and 1983. Life-tabte statistcal analysis showed a cumutative pregnancy rate of 0.40 / 100 women in the first year, 1.07 / 100 women in the sixth year after tubal ligation. The incidence of complications was 2.66%, among which infection was the first in order. The results of multiple stepwise diseriminant analysis showed that the main factors af[ecting the operations were. the type of operation, and the hospital where the operation was performed. Premeroy rate after Madlener‘s operation was significantly higher than that after Pomeroy, modified Pomerov and Uchida operations. Signfieantlv higher pregnaney rate was observed in cases operated in hospitals below the county level than in those performed above cotatty level. The results of investigation indicated that tubal tigation is a safe, reliable, life-long cotraceptive measure.     

Investigation on the Purification and Expression of Cell Ⅰ－Hep Ⅱ Recombinant FN Polypeptide in E．Coli

ＩｎｖｅｓｔｉｇａｔｉｏｎｏｎｔｈｅＰｕｒｉｆｉｃａｔｉｏｎａｎｄＥｘｐｒｅｓｓｉｏｎｏｆＣｅｌｌⅠ－ＨｅｐⅡＲｅｃｏｍｂｉｎａｎｔＦＮＰｏｌｙｐｅｐｔｉｄｅｉｎＥ．ＣｏｌｉＺＨＡＮＧＧｕｉｍｅｉ（张桂梅）；ＦＥＮＧＺｕｏｈｕａ（冯作化）；ＬＩＤｏｎ...     

A Brief Note on Pathogenesis and Treatment of Perthes Disease

ＡＢｒｉｅｆＮｏｔｅｏｎＰａｔｈｏｇｅｎｅｓｉｓａｎｄＴｒｅａｔｍｅｎｔｏｆＰｅｒｔｈｅｓＤｉｓｅａｓｅ￥ＦａｎＷｅｉｍｉｎ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ，１９９４，１４（１）：４４－４６Ａｂｓｔｒａｃｔ：Ｍｅ...     

Perthes病发病机理和治疗的探讨

对４９个Ｐｅｒｔｈｅｓ病髋和３８个正常儿童髋进行股骨上端骨内压的测量、注液加压试验和静脉造影。结果显示Ｐｅｒｔｈｅｓ病股骨上端骨内压明显增高，注液加压试验和股骨上端静脉造影异常，说明Ｐｅｒｔｈｅｓ病股骨上端骨内压增高、静脉回流障碍。我们对３１个Ｐｅｒｔｈｅｓ病髋行中心减压术，优良率为８４％，对１８个严重晚期Ｐｅｒｔｈｅｓ病髋行Ｃｈｉａｒｉ骨盆截骨术，优良率为７７％。我们认为对ｐｅｒｔｈｅｓ早期病例，应行中心减压术，对严重的晚期病例可行Ｃｈｉａｒｉ骨盆截骨术。     

儿童股骨头坏死长期随访报告

目的：对儿童股骨头坏死的多种治疗方法进行分析评价，以总结出系统的治疗方案。方法：对164例患进行长期随访，观察多种方法对本病不同分型和分期的治疗结果，对比其治疗的有效性和适应证。结果：几种方法各有优缺点，治疗的效果与分期和分型及所选的治疗方案间有明显的相关性。I型的各期应以保守治疗为好，Ⅱ型的I期可行较简单的治疗，Ⅲ期一般应不进行手术，Ⅲ型的I期，Ⅱ期，Ⅲ期均可行吻合血管腓骨移植。Ⅳ型的病例，应行多种方法联合治疗。结论：应根据疾病的分期和分型选择具体的治疗方案．     

兔Perthes病模型的影像学研究

采用手术切断圆韧带和支持带的新术式以中断血供法制作兔Perthes病模型，并对其作X线、MRI和病理学研究。X线、MRI和病理学研究结果均表现出与Perthes病相似的特点。表明该方法所制模型成功重复了Perthes病的基本特征。     

儿童股骨头缺血性坏死的治疗进展

儿童股骨头缺血性坏死(Perthes病)极易导致患儿病残，其治疗一直是困扰临床骨科的难题。目前的治疗方法效果难以令人满意，重建头骺血运及恢复头骺的良好包容状态仍是研究的重点。     

儿童股骨头缺血性坏死Chiari骨盆截骨术中可吸收棒的应用

目的:探讨可吸收棒固定骨盆Chiari截骨的疗效.方法:对我科收治的50例53髋(双侧3例)儿童股骨头缺血性坏死病人,按Herring外侧柱分型:B型16髋,B/C型5髋,c型32髋,均采用Chiari骨盆内移截骨,截骨断端用可吸收棒内固定术.结果:所有患儿获得随访,髋关节功能明显改善,伸屈可达0～120°,疼痛消失,跛行明显改善.复查X片示股骨头均覆盖良好;骨盆截骨处骨痂丰富,骨折线模糊的时间为6～12周,平均8周.仅早期1例骨盆截骨处有回缩,余52髋骨盆内移截骨固定好,无移位,可吸收棒的低密度影在5～6个月时渐消失.结论:可吸收棒代替克氏针应用于骨盆截骨术,操作简单,固定牢靠,可缩短骨折愈合时间,无明显不良反应,避免二次手术,费用减少.     

年轻成人Perthes病的临床表现与MRI研究

目的　研究年轻成人Perthes病的临床表现与MRI表现的相关性。方法　对 12例有或无症状年轻成人Perthes病患者作X线和MRI检查 ,测量CE角、ATD、髋臼商、头颈商、关节内侧间隙和髋臼覆盖率等X线指标 ,以及关节积液、外侧关节囊厚度等MRI表现。统计分析其与临床表现的相关性。结果　MRI检查显示外侧关节囊厚度与愈合后遗的症状有相关性 ,关节积液量有明显的差异趋势 ,但因样本量过少 ,统计学分析无差异 ,各项X线测量指标亦未显示明显的相关性。结论　外侧关节囊厚度与年轻成人Perthes病的临床表现有一定相关性。     

儿童股骨头坏死对颈干角影响的X线观察

目的 探讨儿童股骨头坏死后对颈干角发育的影响。方法 在52例单侧股骨头坏死的儿童骨盆X线平片上,进行颈干角的测量（包括患侧和健侧）,并按照年龄及病情进行分组比较。结果 52例股骨头坏死均为单侧发病,其中右侧20例,左侧32例,按照Catterall标准：Ⅰ、Ⅱ型分别有7例和16例（A组）,Ⅲ、Ⅳ型分别有21例和8例（B组）。颈干角患侧148.9°±13.3°,健侧156.1°±10.2°,健患两侧比较差异有统计学意义（P均<0.01）;A组颈干角患侧较健侧小6.2°±2.3°,B组颈干角变小9.8°±3.7°,A、B组间比较差异有统计学意义（P均<0.01）。发病年龄<9岁患儿组颈干角患侧较健侧小7.3°±3.1°,≥9岁患儿组颈干角小9.2°±4.3°,两者比较差异无统计学意义（P>0.05）。结论 儿童股骨头坏死会影响股骨颈的发育和塑形,使颈干角变小,且病情越严重,后遗影响可能越大。     

历节病并发奔豚病的病机及证治探讨

[目的]探讨历节病并发奔豚病的核心病机及证治方法.[方法]通过查阅并梳理《黄帝内经》《金匮要略》《针灸甲乙经》等经典文献中与历节病、奔豚病密切相关的文献资料,从文献中整理总结历节病和奔豚病的病因,并分析各个证候类型的核心病机,找出相应的辨证论治方法.[结果]文献表明,误汗、误水、误下、劳后当风、饥饿、烧针后感寒是历节病...     

Staheli槽式髋臼延伸术治疗儿童Perthes病

目的:探讨Staheli槽式髋臼延伸术治疗儿童Perthes病的手术适应证及治疗经验.方法:回顾分析2004年1月以来本院采用Staheli槽式髋臼延伸术治疗儿童Perthes病26例.其中,男22例,女4例.右侧18例,左侧8例.手术年龄6岁1个月～14岁3个月,平均7岁2个月.按Catterall分级,Ⅱ级3例、Ⅲ级12例、Ⅳ级11例.结果:术后随访6个月～3年,平均2年1个月.按Mckay标准评定髋关节功能,询问有无髋关节疼痛、跛行,检查髋关节活动程度以及Trendelenburg征,术后优良率达98.16%.X线片随访,采用Willett等正位骨盆片对比测量法,测量骺高比、髋臼覆盖率、CE角、Sharp角,观察Shenton线连续性、股骨头形态.骺高比、髋臼覆盖率、CE角明显增大,Sharp角明显减小,Shenton线连续性、股骨头形态均明显好转.结论:Staheli槽式髋臼延伸术治疗儿童Perthes病手术疗效满意,为治疗儿童Perthes病的一种理想术式.