自拟中药方配合灌肠治疗慢性盆腔炎60例

目的：观察自拟中药方配合灌肠治疗慢性盆腔炎的疗效。方法：将60例患者采用同一自拟中药方配合灌肠治疗,随症做相关调整,采用自身前后对照。结果：痊愈15例,显效30例,有效11例,无效4例,总有效率93％。结论：自拟中药方配合灌肠治疗慢性盆腔炎有显著疗效。     

清热利湿止痛中药方及中药灌肠联合抗生素治疗慢性盆腔炎的临床疗效

目的探讨清热利湿止痛中药方口服加中药保留灌肠结合抗生素治疗慢性盆腔炎的临床疗效。方法将80例慢性盆腔炎患者,随机分为治疗组40例、对照组40例。治疗组予中药方口服及中药灌肠联合抗生素治疗,对照组予抗生素治疗,治疗3月后观察各组的临床疗效。结果两组治疗后效果比较有统计学意义(P0.05)。结论中药方及中药灌肠联合抗生素治疗慢性盆腔炎疗效显著。     

自拟中药方内服配合中药灌肠微波治疗慢性盆腔炎疗效观察

目的探讨自拟中药方内服配合中药灌肠微波治疗慢性盆腔炎临床疗效.方法回顾性分析我院2009年6月-2011年2月收治入院的经确诊慢性盆腔炎患者100例临床资料,将100例患者随机分治疗组和对照组,治疗组50例采用自拟中药方内服配合中药灌肠微波治疗,对照组50例采用西药治疗,均治疗3周期,观察2组的疗效.结果治疗组痊愈38例,有效7例,无效5例,总有效率为90%,对照组痊愈10例,有效10例,无效30例,总有效率40.0%,两组疗效比较差异有显著性(P<0.05).出现恶心、厌食等药物副作用的,治疗组3例,对照组5例,均未经处理自行消失.结论自拟中药方内服配合中药灌肠微波治疗慢性盆腔炎有显著疗效,可在临床广泛推广.     

中西医结合治疗慢性非特异性溃疡性结肠炎128例

为观察自拟中药保留灌肠加柳氮磺胺吡啶（SASP）口服治疗慢性非特异性溃疡性结肠炎（UC）的疗效,将238例UC患者,随机分成治疗组128例采用自拟中药保留灌肠加SASP口服,对照组110例用SASP加思密达口服治疗。治疗组完全缓解率为43．0％,显效率为25．0％,总有效率为89．06％;对照组分别为27．3％、20．9％和70．91％。两组完全缓解率、显效率、总有效率差异有统计学意义。结果表明采用自拟中药保留灌肠加SASP口服治疗UC有较好的疗效。     

盆腔治疗仪配合中药保留灌肠治疗慢性盆腔炎50例的疗效观察

目的观察盆腔治疗仪配合中药灌肠治疗慢性盆腔炎的疗效。方法100例患者随机分为两组,治疗组50例采用盆腔治疗仪配合中药保留灌肠治疗;对照组50例采用传统的抗生素联合活血化瘀中成药治疗。结果治疗组有效率94％,对照组为80％,治疗组疗效优于对照组（X^2=8．200,P=0．006）。结论盆腔治疗仪配合中药保留灌肠治疗慢性盆腔炎疗效肯定方法简便。     

中草药保留灌肠治疗慢性盆腔炎的临床观察

分别采用自拟Ⅰ号方、Ⅱ号方中草药保留灌肠治疗慢性盆腔炎57例，并设采用抗生素治疗的55例为对照组，结果：治疗组显效43例，有效11例，无效3例；对照组显效11例，有效24例，无效20例；治疗组疗效明显优于对照组。     

中药灌肠治疗慢性盆腔炎f临床观察

目的观察中药保留灌肠治疗慢性盆腔炎的临床疗效。方法将182例慢性盆腔炎患者随机分成2组,静脉给药抗炎1周后,治疗组91例加用中药保留灌肠治疗;对照组91例改用口服抗生素治疗。结果治疗组总有效率为79．12％,对照组总有效率为26．37％,2组比较有非常显著的差异（P〈O．01）。结论中药保留灌肠辅助治疗对治疗慢性盆腔炎疗效确切。     

自拟中药结合西药治疗慢性盆腔炎60例临床观察

目的：观察中药口服、外敷、灌肠结合抗菌药物治疗慢性盆腔炎的疗效。方法：对2006年4月-2008年1月我院确诊慢性盆腔炎患者116例，随机分为：观察组60例采用自拟中药口服、外敷、灌肠结合抗菌药物治疗；对照组56例行西药抗菌药物治疗。结果：中西医结合组总有效率96．7％，明显高于对照组84．5％。（P〈0.01）。结论：中西医结合治疗慢性盆腔炎疗效好，值得推广。     

慢性肾功能衰竭的护理干预

目的探讨慢性肾功能衰竭的护理干预。方法70例慢性肾功能衰竭患者按治疗方法不同分为治疗组35例和对照组35例，两组在常规血透的基础上，治疗组：采用中药高位保留灌肠，对照组采用西药治疗，观察两组疗效和整体护理干预的效果。结果治疗组35例，显效5例（14．3％），有效23例（65．7％），无效7例（20．0％），总有效28例（80．0％）；对照组35例，显效3例（8．6％），有效18例（51．4％），无效14例（40．0％），总有效21例（60．0％）；治疗组总有效率明显高于对照组（χ^2=3．45，P〈0．05）；护理干预可以阻止或延缓了慢性肾功能衰竭的进程。结论慢性肾功能衰竭患者中药保留灌肠的综合护理干预对提高疗效有一定的作用。     

中药口服、灌肠及微波相结合治疗慢性盆腔炎临床观察

目的：观察中药口服、灌肠及微波相结合治疗湿热瘀结型慢性盆腔炎的l阮秉疗效。方法：将80例湿热瘀结型慢性盆腔炎患者随机分为两组,治疗组采用中药口服、灌肠及微波相结合的治疗方法;对照组在前者治疗的基础上给予抗生素治疗。14天为1个疗程,共3个疗程。结果：治疗组45例患者中,临床痊愈18例,显效17例,有效6例,总有效率91．11％,对照组3s例患者中,临床痊愈12例,显效14例,有效5例,总有效率88．57％。两组相比较临床疗效无显著性差异（P〉O．05）。结论：中药口服、灌肠及微波相结合治疗慢性盆腔炎临床疗效肯定,治疗组与对照组两种治疗方法对慢性盆腔炎有效率无差异。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.