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1.
OBJECTIVE: To examine ocular findings in Japanese children with nephrotic syndrome who receive prolonged corticosteroid treatment. METHODS: Information was retrospectively obtained from each patient's record. RESULTS: A total of 45 children (30 boys and 15 girls) were enrolled. Twenty-one patients (46.7%) had epiblepharon with inverted eyelashes. The incidence of epiblepharon was associated with overweight and obesity. Fifteen patients (33.3%) developed posterior subcapsular cataract in both eyes. Of the 15 patients, 4 had visual acuity less than 0.4 and underwent cataract extraction in both eyes. Nine patients (20%) developed intraocular pressure higher than 22 mm Hg during corticosteroid treatment. The total dose and duration of corticosteroid treatment were associated with cataract formation but were unassociated with elevated intraocular pressure. One boy had elevated intraocular pressure after cessation of corticosteroid therapy and underwent trabeculectomy. One patient had repeated hordeolum in the left eyelid. Three patients had bilateral bacterial conjunctivitis. CONCLUSION: Children with nephrotic syndrome who receive corticosteroid treatment may have epiblepharon, cataract, ocular hypertension, hordeolum and bacterial conjunctivitis.  相似文献   

2.
PURPOSE: To determine whether preoperative reading tests can be used for differentiating visual impairments with regard to the diagnosis of cataract and age-related macular degeneration (ARMD). SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: Reading performance of patients with nuclear cataract, posterior subcapsular cataract, and ARMD were evaluated with respect to reading acuity, maximum reading speed, and critical print size; normal-sighted participants were tested as controls. A multivariate discriminant analysis of the 4 groups (100 eyes of 100 participants) was performed to evaluate how many patients could be correctly diagnosed by significant differences in the tested reading parameters. Subsequently, the nuclear cataract and posterior subcapsular cataract patients were compared with cataract patients with coexisting ARMD. RESULTS: Distance visual acuity was comparable in the nuclear cataract, posterior subcapsular cataract, and ARMD groups (P>.05). Reading acuity was significantly reduced in posterior subcapsular cataract and ARMD patients compared with nuclear cataract patients and controls (P<.0001). No significant difference in maximum reading speed was found between the nuclear cataract patients and the controls (P = .07), whereas the maximum reading speed of the posterior subcapsular cataract and ARMD patients was significantly reduced (P<.0001). In the discriminant analysis, it was possible to assign the correct diagnosis to 72% of the nuclear cataract patients, 76% of the posterior subcapsular cataract patients, 72% of the ARMD patients, and 92% of the controls. Comparing the reading performance of nuclear cataract and posterior subcapsular cataract patients and cataract patients with coexisting ARMD showed that reading performance was significantly impaired in the comorbid patients (nuclear cataract and ARMD, P<.001; posterior subcapsular cataract and ARMD, P<.05). CONCLUSION: The high discriminant accuracy shows that this standardized reading test system is a valuable diagnostic tool for evaluating functional visual impairments when distance visual acuity alone cannot elucidate the origin of functional impairment. Considering the significant discrepancies in reading performance among patients with nuclear cataract, posterior subcapsular cataract, and ARMD, reading tests may relevantly improve the clinical evaluation of patients with visual loss, even of patients with ocular comorbidity.  相似文献   

3.
Forty-five patients with nephrotic syndrome were included in our study. Of these, 30 received adrenocorticosteroid therapy and 15 did not. The ages of the patients ranged from 11 months to 27 years and the duration of steroid therapy from 2 1/2 years to 20 years. Seventeen patients (38%) showed posterior subcapsular cataract (PSC) formation and, of these, seven patients (41%) showed reversal of PSC. There was no statistical correlation between the total dose of steroids and the degree of PSC. An individual susceptibility may be an important factor in the production of PSC. None of the patients had visual acuity less than 20/30.  相似文献   

4.
BACKGROUND: To evaluate rates of intraoperative posterior capsule complications in manual small-incision cataract surgery of eyes with and without pseudoexfoliation syndrome in terms of cataract maturity level. METHODS: We identified patients who had undergone manual small-incision cataract surgery between January 1997 and October 2003 from a review of patient charts. Preoperative data collected were cataract maturity level, best corrected visual acuity, and intraoperative posterior capsule complications as documented in the surgical report, namely (1) posterior capsule rupture or zonulolysis, or both, and (2) vitreous loss. RESULTS: Two hundred and twenty-five eyes of 187 patients met the study criteria, of which 99 eyes had pseudoexfoliation syndrome (group 1) and 126 did not (group 2). Intraoperative posterior capsule complications occurred in 18 eyes (18%) in group 1 and 7 eyes (5.5%) in group 2 (difference was significant at p=0.003). The rate of capsular complications was significantly higher in both groups for eyes with preoperative visual acuity worse than 20/200 than for eyes with 20/200 or better. The number of eyes with visual acuity worse than 20/200 (counting fingers, hand motion, or light perception) was 70 (70%) in group 1 and 63 (50%) in group 2. Mature or brunescent cataract occurred in 49.5% of group 1 eyes and 26% of group 2 eyes. INTERPRETATION: In manual small-incision cataract surgery, pseudoexfoliation syndrome has an increased intraoperative posterior capsule complication rate that increases as the level of cataract maturity increases and the preoperative visual acuity decreases.  相似文献   

5.
PURPOSE: To evaluate the outcomes of cataract surgery in patients with Vogt-Koyanagi-Harada's (VKH) syndrome. SETTING: Medical Research Foundation, Sankara Nethralaya, Chennai, India. Methods: Fifty-nine eyes of 39 patients with VKH syndrome who had cataract surgery between May 1985 and June 2001 were retrospectively analyzed. RESULTS: Extracapsular cataract extraction (ECCE) with intraocular lens (IOL) implantation was performed in 15 eyes and without IOL implantation in 31 eyes. Phacoemulsification with IOL implantation was performed in 13 eyes. Twenty-three eyes (38.9%) had mixed cataract (posterior subcapsular and posterior polar). Small pupils were managed by synechiolysis with an iris spatula (43 eyes) or iris hooks (8 eyes). Nine eyes were lost to follow-up and not included in the postoperative analysis. The mean postoperative follow-up was 39.4 months (range 9 to 120 months). Visual acuity improved by 1 or more lines in 40 eyes (80.0%). Subretinal gliosis and optic atrophy, sequelae of the syndrome, restricted improvement in vision in the remaining eyes. Posterior capsule opacification developed in 38 eyes (76.0%), of which 21 (42.0%) required a neodymium:YAG laser posterior capsulotomy. There were no significant differences in postoperative inflammation or syndrome reactivation between the types of surgery. CONCLUSIONS: The results show that cataract extraction in patients with VKH syndrome can be safely and successfully performed if there are good preoperative and postoperative control of inflammation, careful surgical planning, and meticulous surgical technique. The final visual outcome depends on the posterior segment complications of the syndrome.  相似文献   

6.
Purpose: To evaluate the intraoperative and early postoperative complications of phacoemulsification using a ‘phaco chop’ technique in previously vitrectomized eyes. Methods: A prospective interventional case series. Seventy‐five previously vitrectomized eyes of 73 consecutive patients underwent phacoemulsification using a ‘phaco chop’ technique via clear corneal incision. Patients were observed for any intraoperative or early postoperative complications. Results: Fifty‐four eyes (72%) had predominant nuclear sclerosis or posterior subcapsular cataract. The intraoperative findings included intraoperative miosis [seen in 21 eyes (28%)] and posterior capsule plaques [in 15 eyes (20%)]. No other significant intraoperative complication (posterior capsule rupture, zonular lysis or dropped nuclei) was observed. In the early postoperative period, one patient had massive serous choroidal detachment, which resolved with conservative treatment. Mean preoperative visual acuity (LogMar scale) was 0.74, which improved to 0.36 postoperatively (p < 0.001). Conclusion: Phacoemulsification using a ‘phaco chop’ technique is a safe procedure in vitrectomized eyes.  相似文献   

7.
《Ophthalmology》1987,94(5):483-487
Cataract extractions were performed in 25 patients who had previously undergone pars plana vitrectomy. Posterior chamber IOLs were implanted in 20 of 26 eyes. Modification of the usual surgical technique was often necessary because the zonules and/or posterior capsule were unusually mobile. Lens opacities were nuclear sclerotic in 17 eyes (65%) and posterior subcapsular in nine eyes (35%). Visual acuity improved an average of five lines, and final visual acuity was 20/50 or better in 13 eyes (50%). Visual acuity after cataract extraction closely paralleled the best visual acuity after vitreous surgery in all patients. Complications were tears in the posterior capsule in two eyes and postoperative vitreous hemorrhage in one eye. These complications did not limit final vision.  相似文献   

8.
Purpose: To describe the 3‐year risk of cataract after intravitreal triamcinolone (IVTA) injections for diabetic macular oedema and the outcomes of cataract surgery. Methods: Prospective data from a randomized clinical trial were analysed. At baseline, 27 phakic eyes with diabetic macular oedema were randomized to receive IVTA and 25 to receive sham injection. After 2 years, initial sham‐treated eyes were eligible to receive IVTA as the study became open label for the third year. The cumulative incidence of cataract surgery was the primary outcome of the study. Other outcomes assessed included progression of cataract, best‐corrected logarithm of the minimal angle of resolution visual acuity before and after surgery and central macular thickness. Results: Over the 3 years of the study, 15/27 (56%) phakic eyes in the IVTA treated group underwent cataract surgery as compared with 2/25 (8%) initial sham‐treated eyes (P < 0.001). Mean visual acuity 6 months after cataract surgery was better than at entry into the trial. Two (15%) of the eyes in the IVTA‐treated group undergoing cataract surgery had a loss of >15 letters. In the IVTA‐treated group, 10/15 (67%) eyes that had three or more injections had progression of posterior subcapsular cataract by ≥2 grades as compared with only 2/12 (17%) eyes that had fewer than three injections (P = 0.009). Conclusions: Over half of the eyes receiving IVTA injections for diabetic macular oedema required cataract surgery within 3 years. In eyes with three or more IVTA injections, two‐thirds had progression of posterior subcapsular cataract. Visual outcomes after cataract surgery were generally good, although a small proportion of eyes lost greater than 15 letters over the course of the study.  相似文献   

9.
AIM: To determine the relative risk of a poor visual outcome following posterior capsule rupture during cataract surgery. METHODS: Prospective data were collected on consecutive eyes undergoing cataract extraction. The patient's age, preoperative visual acuity, ocular comorbidity, grade of surgeon, and operative complications were documented. The best spectacle corrected visual acuity was recorded at discharge from the hospital service. RESULTS: From a total of 1533 cases, 1420 (92.6%) eyes had complete follow up data. Posterior capsule rupture occurred in 59 (4.1%) cases. Eyes with posterior capsule rupture were 3.8 times more likely to have a final best spectacle corrected visual acuity less than 6/12. CONCLUSIONS: Eyes having posterior capsule rupture during cataract surgery have a significant risk of reduced visual acuity.  相似文献   

10.
目的:探讨小角膜合并先天性白内障患者的眼部临床表现、手术治疗时机及疗效。

方法:回顾性分析2000-01/2012-12在天津医科大学眼科中心接受治疗的先天性白内障合并小角膜患者11例18眼的临床资料,术前检查包括角膜直径(<9.5mm)、眼部异常和全身异常,术后随访至少1a,评价术后视力和并发症等。

结果:患者11例中有先天性白内障家族史4例,18眼中合并虹膜缺损6眼,眼球震颤18眼,原始玻璃体动脉残留1眼。对11例18眼患者施行三种手术方案:(1)行囊外白内障摘除术(extra capsular extraction of cataract, ECCE)者5眼;(2)Ⅰ期行ECCE,Ⅱ期行人工晶状体植入术(posterior chamber intraocular lens,PC-IOL)者4眼;(3)Ⅰ期行ECCE联合PC-IOL植入者9眼。术后患者视力均有明显改善,18眼术后最佳矫正视力0.145±0.0958(0.01~0.20)。ECCE术中并发症主要为后囊破裂1眼,术后并发症主要为后发性白内障10眼,继发性青光眼2眼。

结论:先天性白内障合并小角膜常伴发虹膜、脉络膜缺损,眼球震颤等合并症,人工晶状体的植入能明显提高患者视力,但术中应注重防范角膜损伤、后囊破裂等并发症,术后加强管理,特别是眼压的监测,以极早防治青光眼等并发症。  相似文献   


11.
PURPOSE: To analyze the results of cataract surgery in patients with sympathetic ophthalmia. SETTING: Sankara Nethralaya, Medical Research Foundation, Chennai, India. METHODS: This study comprised 66 patients (132 eyes) with sympathetic ophthalmia seen at the uveitis referral clinic between January 1990 and July 2001; 42 eyes (31.8%) had cataract. Cataract surgery was performed in 17 sympathizing eyes and 1 exciting eye (17 patients). The records of these 18 eyes were retrospectively analyzed. Three eyes had extracapsular cataract extraction (ECCE) with intraocular lens (IOL) implantation, 6 eyes had ECCE without IOL implantation, and 9 eyes had phacoemulsification with IOL implantation. The mean follow-up was 28.7 months (range 3 to 60 months). RESULTS: The causes of sympathetic ophthalmia were penetrating trauma (n = 8 eyes), ocular surgery (n = 6), perforated corneal ulcer (n = 2), and cyclocryotherapy (n = 1). The most common cataract type, present in 7 eyes (38.8%), was mixed (posterior subcapsular and posterior polar). Visual acuity improved after surgery in 13 eyes (72.2%). The main factors impairing visual recovery were submacular scar and optic atrophy, which were sequelae of the sympathetic ophthalmia. Posterior capsule opacification was noted in 14 eyes (77.7%); it was visually significant in 6 eyes. There was no significant difference in postoperative inflammation or disease reactivation between the 3 types of surgery. CONCLUSIONS: Cataract extraction in cases of sympathetic ophthalmia can be safely and successfully performed with vigilant preoperative and postoperative control of inflammation, careful surgical planning, and meticulous surgical technique. The final visual outcome, however, depends on the posterior segment complications of the disease.  相似文献   

12.
Posterior subcapsular cataracts studied in 86 eyes of 86 patients transplanted for keratoconus were retrospectively studied. The follow-up period ranged between one and four years with a median of 18 months. Twenty-eight eyes developed posterior subcapsular cataracts. The development of posterior subcapsular cataracts was significantly related to the total cumulative steroid dose and the total time steroids were administered (p less than 0.01). Age, surgical technique, and rejection episodes could not be significantly correlated with development of a posterior cataract. The progression of the cataract appeared to be slow, and if topical steroids were discontinued the lens changes appeared to stabilize and progressed in only one patient. The effect of an early posterior subcapsular cataract on visual acuity was minimal in the early stages.  相似文献   

13.
Sixty-one renal transplant patients were studied for ocular complications of steroid therapy. Twenty patients (32.8%) were found to have posterior subcapsular cataract. Three patients (4.9%) had ocular hypertension. There was no significant correlation between cataract formation and the total dose of steroids, number of rejection episodes, or the period of hemodialysis. HLA-A9 was present in noncataract patients to a greater extent, a statistically significant (P less than .05) finding not reported before to our knowledge.  相似文献   

14.
Results of late surgery for presumed congenital cataracts.   总被引:6,自引:0,他引:6  
We reviewed the results of cataract extraction and visual rehabilitation in 76 eyes of 47 infants and children with presumed congenital cataracts who were first seen after they were 10 months old. Eighteen patients underwent surgery for unilateral cataracts, including five patients with persistent hyperplastic vitreous, five with posterior lenticonus, one with a nuclear cataract, six with posterior subcapsular cataracts, and one with a lamellar cataract. Of these 18 patients, seven (39%) attained a visual acuity of 20/60 or better, one (6%) had a visual acuity of 20/100, and ten (60%) had a visual acuity of 20/200 or worse. Twenty-nine patients (62 eyes) underwent bilateral cataract extraction. The visual acuity could be measured in 22 patients (44 eyes). Visual acuity improved to 20/60 or better in 32 eyes (73%), was between 20/70 and 20/150 in 11 eyes (25%), and became worse than 20/200 in one eye (2%). Results were good in patients with persistent hyperplastic primary vitreous, posterior lenticonus, and bilateral cataracts.  相似文献   

15.
Purpose: To determine the prevalence and associations of cataract within the indigenous Australian population living in central Australia. Methods: 1884 individuals aged ≥20 years, living in one of 30 remote communities within the statistical local area of ‘central Australia’ were recruited for this study. This equated to 36% of those aged ≥20 years and 67% of those aged ≥40 years within this district. Slit‐lamp examination was performed. The degree and subtype of cataract was graded using the Lens Opacities Classification System III criteria. A cataract was defined as a nuclear opalescence ≥4.0, a cortical opacity ≥3.0, a posterior subcapsular opacity ≥2.0, a visual acuity worse than 6/12 or a visual acuity worse than 6/60 due to cataract. The prevalence of cataract in one or both eyes was presented for each of the definitions. Results: Nuclear opalescence cataract was present in 13.5% (18.5% of those ≥40 years); cortical opacity cataract was present in 13.1% (17.7% of those ≥40 years); and posterior subcapsular cataract was present in 15.8% (21.0% of those ≥40 years). 12.6% of patients (17.3% of those ≥40 years) and 4.4% of patients (5.9% of those ≥40 years) had a cataract that resulted in a visual acuity of worse than 6/12 and worse than 6/60, respectively. All cataracts were associated with advancing age. Posterior subcapsular cataract was associated with self‐reported diabetes. Conclusion: There is a higher prevalence of cataract among indigenous Australians living within remote central Australia compared with the non‐indigenous population. Services for this population need to be designed with this in mind when planning resource allocation.  相似文献   

16.
PURPOSE: To determine intraoperative and postoperative complications and outcomes of phacoemulsification of cataract in eyes that had previous pars plana vitrectomy. SETTING: University-based anterior segment disease referral practice. METHODS: This was a retrospective case-control study of a surgical series of 52 consecutive postvitrectomy cataract extractions statistically compared with control eyes from the same practice. RESULTS: Cataract extraction followed vitrectomy by 2 months to 6 years (mean 19 months). Cataracts with a posterior subcapsular component were seen more frequently in postvitrectomy eyes (58% versus 25% in control eyes). Cataract extraction after pars plana vitrectomy was often more challenging than in control eyes. Challenges included unstable posterior capsules, loose zonules, and posterior capsule plaque. Postoperative posterior capsule opacification (PCO) was more common in study than in control eyes (51% versus 21%; P = .002), especially if expandable gas or silicone oil had been used at vitrectomy. Visual acuity improved in 87% of study eyes, with 46% achieving a visual acuity of 20/40 or better. In study eyes in which the indication for vitrectomy was macular hole or epiretinal membrane, nuclear sclerosis was the most common cataract type, no intraoperative complications occurred, the PCO rate was low (13%), and visual acuity was better (73% 20/40 or better) than in the other study eyes. CONCLUSION: Phacoemulsification after pars plana vitrectomy can be performed with a low complication rate and with good visual results, although limited by underlying retinal disease. Posterior capsule opacification requiring neodymium: YAG capsulotomy was common in this series.  相似文献   

17.
Purpose: To evaluate the long‐term visual outcome after early surgery of bilateral dense congenital cataracts, aphakic correction with glasses and secondary intraocular lens (IOL) implantation around 2 years of age. Methods: The medical records of paediatric patients who underwent cataract extraction, aphakic correction and secondary IOL implantation from 1993 to 2004 at Seoul National University Children’s Hospital were reviewed retrospectively. Age at secondary IOL implantation, axial length (AL), best corrected visual acuity (BCVA), refractive error, ocular alignment, stereopsis, and postoperative ocular complications were recorded. Results: Thirty‐seven paediatric bilateral pseudophakic patients were identified with a mean follow‐up period of 81.4 months. Best corrected visual acuity of 20/40 or better were attained in 44.0% of eyes, and the median BCVA was 20/50. Preoperative factors associated with poor visual prognosis included cataract surgery after 8 weeks of age, interocular AL difference of 0.5 mm or more, and glaucoma. Amblyopic eyes showed more myopic change compared to fellow eyes. Good or moderate binocular function was achieved in 18.9% of all patients. Incidences of strabismus, glaucoma, posterior capsular opacity formation were 46.0%, 32.4% and 4.0%, respectively. Conclusion: Good postoperative BCVA and binocular function were achieved in most healthy children with bilateral dense congenital cataract and no posterior segment pathology. Early cataract surgery, aphakic correction with glasses and secondary IOL implantation around 2 years of age appears to be appropriate methods.  相似文献   

18.
BACKGROUND: Cataract remains a challenge for ophthalmologists in uveitic eyes. The aim of this study is to report the clinical course of phacoemulsification with intraocular lens implantation in eyes suffering from uveitis. PATIENTS AND METHODS: Patients presenting a uveitis were prospectively followed from June 2001 to June 2003. Ocular surgery was performed according to a standard protocol, autoimmune follow-up visits were focused on the early detection of complications of uveitis: increased ocular inflammation, synechiae, retraction of the rhexis, opacification of the posterior capsule or onset of cystoid macular edema. RESULTS: Thirty-two eyes of 24 patients suffering from uveitis were operated with cataract surgery between June 2001 and June 2003. The mean age at surgery was 56 years (range 24 - 86 years). Mean preoperative visual acuity in uveitis patients presenting cataract was 0.3 +/- 0.3, and final visual acuity was 0.8 +/- 0.3. Three patients presented minor postoperative complications. One patient had a cystoid macular edema that appeared 5 months after surgery and one patient had a relapse of herpetic dendritic keratopathy despite topical antiviral therapy combined with steroid drops. The latter presented a slight increase of intraocular pressure (24 mm Hg). CONCLUSIONS: In patients with uveitis requiring cataract surgery, intraocular lens implantation is safe. Visual prognosis is better when pre- and postoperative inflammation is minimized. Macular scars or other retinal lesions are poor prognostic indicators.  相似文献   

19.
目的:观察3.2mm切口手法碎核白内障摘除联合折叠式人工晶状体植入术的临床效果。

方法:观察组:对我院78例95眼老年性白内障行3.2mm切口手法碎核白内障摘除联合折叠式人工晶状体植入术; 对照组:对同期82例100眼老年性白内障行超声乳化白内障摘除联合折叠式人工晶状体植入术。观察并比较手术并发症及术后视力恢复情况。

结果:观察组术中有2眼(2.1%)后囊膜破裂,3眼(3.2%)局限性悬韧带离断。术后切口方位角膜轻中度水肿混浊18眼(18.9%),1wk内前房闪辉22眼(23.2%)。对照组术中有3眼(3.0%)发生后囊膜破裂,4眼(4.0%)局限性悬韧带离断。术后角膜轻中度水肿混浊21眼(21.0%),1wk内前房闪辉26眼(26.0%)。两组均无后弹力膜脱离、前房出血、伤口渗漏及感染发生。两组并发症比较差异无统计学意义(P>0.05)。两组术后视力比较差异无统计学意义(P>0.05)。

结论:3.2mm切口手法碎核行白内障摘除联合折叠式人工晶状体植入术操作安全、简便,具有小切口手术的优点,适于临床推广和普及。  相似文献   


20.
目的 报道对平部玻璃体切割术后病人施行白内障超声乳化术的经验。方法 1994年6月至1998年6月共为26例平部玻璃体切割术后的病人施行了白内障超声乳化术,并进行回顾性分析。所有病人的原始指征及睫状体平坦部手术的次数,白内障类型及术前视力均予记录,并分析术中及术后并发症,还对比分析了最终视力与术前潜在视力测量仪(PAM)的预测视力。结果 本文26例中有18例(69.2%)曾作过1次平部玻璃体切割术,7例(26.9%)作过2次,1例(3.8%)作过3次。增殖性糖尿病视网膜病变(38.5%)及视网膜脱离(23.7%)是常见的玻璃体切割术指征;后囊下白内障是主要类型,共13例(50%)。术中并发症包括小瞳孔 4例(15.5%),后囊玻裂1例(3.8%),可见度不良2例(7.7%),后囊斑2例(7.7%)及前房过深2例(7.7%)。术后早期主要并发症有13例(50%)出现角膜水肿并持续1周,但所有病例至术后第4周角膜透明。后囊混浊5例(19%)。9例最终视力≤0.5,另8例发现患有明显的视网膜及视神经病变。其中13例最终最好的矫正视力等于或超过PAM预测视力,而另2例却低于PAM视力。结论 白内障超声乳化吸出术对玻璃体切割术后眼的白内障是一种安全有效的方法。后囊下白内障是这类患者中最主要的类型。小瞳孔,可以抛光的后囊斑及前房过深是常见的木中并发症。角膜  相似文献   

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