居民吸烟状况调查分析

目的 了解不同人群的吸烟状况,制定切实可行的控烟健康教育对策、措施.方法 按照不同职业进行分层整群抽样,采取自行设计的调查问卷,共调查居民821人.结果 调查的821人中总吸烟率为30.9%,男性吸烟率46.9%高于女性吸烟率4.1名(x2=195.138,P<0.001).吸烟者中大多数人(89.6%)每日吸烟量为10～20支,男性开始吸烟的平均年龄(18.16±4.56岁)小于女性(27.21±9.39岁).在吸烟者中曾经试图戒烟3次及以上的人数占45.3%(115/254).结论 居民吸烟率仍然很高,烟草控制仍然面临巨大挑战.     

冠心病患者血管重建后吸烟状态对临床预后的影响

目的 探讨冠心病患者血管重建后吸烟状态对其长期临床预后的影响.方法 将893例冠心病患者根据血管重建术前及术后的吸烟状态分为3组:不吸烟组(n=458)、戒烟组(n=287)及吸烟组(n=148),详细记录随访时主要不良心脑血管事件(MACCE)的发生情况.Kaplan-Meier生存分析描述术后累计生存率,并比较吸烟状态对全因性死亡及MACCE的影响,Cox多元逐步回归分析全因性死亡及MACCE的影响因素.结果 平均随访时间约为27个月,术后吸烟率较术前吸烟率明显降低(16.57％ vs.48.71％),且吸烟组患者较年轻(P＜0.0l);不吸烟组患者多为女性(P＜0.01),体质量指数(BMI)较小(P＜0.01).吸烟组全因性死亡(1.53％ vs.1.05％ vs.6.76％,P=0.002)和MACCE(4.37％ vs.5.23％ vs.15.54％,P=0.001)的发生率较高,Cox多元逐步回归分析显示,术后持续吸烟是导致全因性死亡[HR=2.753,95％CI(1.695～4.473),P＜0.01]和MACCE[HR=1.552,95％CI(1.049～1.754),P=0.001]发生的重要危险因素.结论 冠心病患者血管重建后持续吸烟是导致术后发生全因性死亡和MACCE的独立危险因素.     

北京房山农村社区人群8年干预对冠心病及脑卒中危险因素的影响

探讨心血管病的社区人群综合性防治对农村人群心血管病危险因素的影响。方法1991～1999年对北京郊区农村12万自然人群,按整群抽样的方法分为干预区和对照区,在干预区采取以健康教育和高血压防治为主的综合干预措施。于1991、1995和1999年分别采用随机抽样的方法分析干预区和对照区心血管病危险因素的变化,评价干预效果。研究的危险因素包括收缩压、舒张压、体重指数、吸烟、饮酒、血清胆固醇、甘油三酯和高密度脂蛋白胆固醇。结果1991～1999年,干预区人群收缩压、舒张压、吸烟率和饮酒率出现下降趋势,其中男性收缩压下降1.6mmHg(P＞0.05),舒张压下降1.1mmHg(P＞0.05),吸烟率下降14.5％(P＜0.01),饮酒率下降3.7％(P＞0.05);女性收缩压下降4.8mmHg(P＜0.01),舒张压下降3.2mmHg(P＜0.01);对照区人群收缩压、舒张压和吸烟率也有小幅度下降。干预和对照社区人群体重指数、血清胆固醇和甘油三酯水平都有所上升,高密度脂蛋白胆固醇有所下降。1991～1999年,干预区人群多数危险因素有净下降。结论以健康教育为主的一级预防以及人群高血压筛查、管理、指导治疗等干预措施对降低群体血压水平和吸烟、饮酒率有一定效果,但体重指数和血脂的改变尚未达到预期的结果。     

150例肺癌的病因学分析

目的探讨肺癌与年龄、性别、吸烟、空气污染、慢性肺部疾病等之间的关系.方法150例肺癌患者经胸部X线、CT及痰、胸、水、纤维支气管镜刷检、淋巴结活检、开胸手术等病理和细胞学检查证实,并与临床资料进行回顾性分析.结果肺癌的发病随年龄的增长而升高,以60岁～69岁组上升最显著.肺癌中吸烟者占77.3%,吸烟指数≥400年支者肺癌发病率明显高于吸烟指数＜400年支者(P＜0.001).肺鳞癌、未分化癌和男性的肺腺癌吸烟率分别为97.3%、92.3%和85.7%,与吸烟关系密切.女性肺癌、尤其是肺腺癌与吸烟关系较小,男、女吸烟率相比差异显著(P＜0.001).肺癌患者中近半数合并有慢性肺部疾病,其中合并慢性阻塞性肺病,肺结核,支气管扩张,矽肺者分别为25.3%、12.7%、2.0%、2.0%.结论肺癌是一种多因素的疾病,吸烟是引起肺癌的主要病因之一.女性肺癌与吸烟关系较小,推测与室内煤烟,烹调油烟的长期接触有关.慢性肺部疾病,在不同程度上增加了肺癌发生的危险性.     

北京市大、中、小学生吸烟状况调查

目的: 了解北京市大、中、小学生吸烟状况.方法: 采用多阶段整群抽样方法,对北京市城区、近郊区和远郊区的4所非医学类大学、6所中学和6所小学进行自填式问卷调查.结果: 被调查学生中尝试吸烟率为22.5%,现在使用卷烟制品率为8.5%,现在吸烟率为7.2%.尝试吸烟率、现在使用卷烟制品率和现在吸烟率均是男生高于女生(P＜0.05),在读大学生高于其他学历在读学生(P＜0.05),好朋友中有人吸烟者高于好朋友中无人吸烟者(P＜0.05).父母中有人吸烟的学生尝试吸烟率较高(P＜0.05).18岁以下的中、小学生因年纪小买烟被拒率在性别和在读学历间的差异没有统计学意义(P＞0.05),但现在吸烟的学生更易买到香烟(P＜0.05).现在吸烟的学生更认同吸烟能增加男孩和女孩的吸引力(P＜0.05).结论: 北京市大、中、小学生吸烟现状不容乐观,必须加大宣传力度,采取积极的干预措施,促使青少年不进入或者尽早退出吸烟者队伍.     

冠心病传统心血管病危(险因素的评价

目的 探讨传统的心血管病危险因素对冠心病(CHD)的价值.方法 对283例急性冠脉综合征(ACS)患者传统的心血管病危险因素(性别、年龄、高血压、糖尿病、血脂异常、吸烟)作回顾性分析.结果 男女CHD均以老年多见(χ2 =15.204,P＜0.001));＜60岁男女对比差异有统计学意义(χ2 =8.803,P＜0.01);283例CHD患者仅高血压与其它各危险因素对比差异有统计学意义(P＜0.001),等级相关及回归分析仅高血压与CHD有显著相关(r =0.993,t=15.654,P＜0.001).男性CHD以合并高血压及吸烟因素居多,女性CHD以高血压及糖尿病因素居多,男女CHD对比吸烟、糖尿病因素差异均有统计学意义(χ2 =23.916、χ2 =11.740,P＜0.001).高TG、低HDL-C与高TC、高LDL-C对比均差异有统计学意义(P＜0.05).除外性别、年龄随着危险因素数目的 增多CHD增加,合并2个危险因素组最多见,为35.3%,2个以上危险因素组冠心病并未随着危险因素增多而增加.结论 老年、高血压是CHD独立的危险因素;吸烟是男性CHD主要的危险因素,糖尿病是女性CHD主要的危险因素;男女CHD患病率与年龄有关,＜60岁时男性CHD发病率高于女性;血脂异常中高TG、低HDL-C为CHD主要的危险因素;CHD合并2个危险因素最多见.CHD的防治不仅要重视高危人群,也要加强低危人群的宣教和预防,综合干预和积极控制已明确的危险因素,可能对降低心血管疾病的发病率和死亡率具有积极作用.     

112例输尿管结石患者尿枸橼酸和尿钙含量的测定

目的:测定112例输尿管结石患者24 h尿枸橼酸、尿钙含量,并分析两者相关性.方法:收集2006年7月至2007年6月112例输尿管结石患者及48例对照者的24 h尿液,测定其24 h尿枸橼酸值及尿钙含量,分析二者相关性.结果:输尿管结石患者24 h尿枸橼酸含量(mg)明显低于对照人群(289.48±147.66 vs 485.49±133.77,P＜0.001),且低枸橼酸尿症(＜320 mg/24 h)者明显多于对照人群(66.1% vs 9.8%,P＜0.001),性别对尿枸橼酸影响不大.输尿管结石患者24 h尿钙(mmol) 高于对照组 (8.52±2.79 vs 6.28±1.83,P＜0.001),而高钙尿(＞7.5 mol/24 h)人数明显多于对照组(51.7% vs 19.5%,P＜0.001),性别对尿钙影响不大.尿枸橼酸、尿钙水平之间未发现线性相关.结论:输尿管结石患者常常伴有低枸橼酸尿症和高钙尿症,但尿枸橼酸水平和尿钙含量无明显相关,性别对患低枸橼酸尿症或高钙尿症无明显影响.     

MPO-ANCA相关性血管炎患者中性粒细胞外捕网与滤泡辅助T细胞间关系的探讨

目的 探讨抗中性粒细胞胞质髓过氧化物酶抗体相关性血管炎(MPO-AAV)患者中性粒细胞外捕网(NET)与滤泡辅助T细胞(Tfh)间关系及意义.方法 选择初诊未治疗的MPO-AAV患者和健康对照者各35例,流式细胞术(FCM)检测所有受试者外周血Tfh占CD4+T细胞分数(Tfh％)、表达 ICOS 的 Tfh 占 CD4+T 细胞分数(ICOS+Tfh％)及Tfh表达ICOS的平均强度(MFI);酶联免疫吸附试验(ELISA)法检测外周血MPO-ANCA、NET及IL-23水平,收集每例受试者的临床资料,评估每例患者病情活动度(BVAS-V3).结果 与健康对照组比较,MPO-AAV组外周血 Tfh％、ICOS+Tfh％、Tfh 的 MFI、NET 及 IL-23水平均高于对照组[分别为(25.7±3.9)％vs(20.7±5.3)％,P＜0.001;(1.9±1.0)％vs(0.8±0.4)％,P＜0.001;(59.5±10.3)vs(48.7±6.4)(MFI),P＜0.001;(0.6±0.2)vs(0.2±0.1)(吸光度),P＜0.001;(0.753 5±0.201 9)vs(0.237 5±0.087 0)(pg/L),P＜0.001].双变量相关性分析提示MPO-ANCA水平分别与Tfh％及Tfh的MFI呈正相关(分别为r= 0.737,P＜0.001;r = 0.628,P＜0.001),但在多变量线性回归分析显示MPO-ANCA仅与Tfh％相关(P＜0.001).IL-23分别与Tfh％、Tfh的MFI及NET水平呈正相关(分别为:r = 0.475,P = 0.004;r=0.359,P = 0.034;r =0.806,P＜0.001).虽然双变量相关性分析提示Tfh％分别与外周血中NET及IL-23水平呈正相关(分别为:r= 0.714,P＜0.001;r=0.480,P =0.004),但多变量线性回归分析显示Tfh％仅与NET水平呈正相关(P＜0.001),即NET是影响Tfh％的独立因素.同时,结果显示NET与肾损害间存在相关性(r = 0.390,P= 0.021).结论 NET可能通过激活髓样树突状细胞提升Tfh％,以辅助B细胞产生特异性自身抗体 MPO-ANCA 参与 MPO-AAV 发病.     

心理干预对肺癌患者生存质量的影响

目的探讨心理干预对肺癌患者心理控制源及生存质量的影响.方法采取病例对照研究方法,将102例临床确诊为原发性肺癌的患者分成二组,一组采用常规化疗方案,另一组在常规化疗的基础上加用心理干预;二组均作了多维度健康状况心理控制源量表、癌症患者化疗生存质量量表等评估.结果1.心理控制源量表中的内控因子、势力因子评分干预组高于对照组(P=0.003～0.009),机遇因子评分干预组低于对照组(P＜0.001);2.化疗生存质量评分结果显示,干预组患者的生理功能障碍[(2.65±0.50)分vs(2.86±0.37)分,P=0.024]、心理功能障碍[(2.78±0.25)分vs(3.29±0.31)分,P＜0.001]、日常活动影响[(2.23±0.61)分vs(2.73±0.69)分,P＜0.001]、社会功能障碍[(2.90±0.52)分vs(3.23±0.53)分,P=0.007]等4方面的评分低于对照组,治疗满意度[(3.49±0.30)分vs(3.14±0.32)分,P=0.001]评分高于对照组.结论心理干预能够改善患者的心理控制源倾向,提高患者的生存质量.     

中国城乡居民吸烟行为及其影响因素分析

目的:了解中国城乡居民吸烟现状及其吸烟行为影响因素,为开展控烟教育及行为干预提供依据?方法:使用中国健康与营养调查(CHNS)2009年数据,对9 995名(男4 763人,女5 232人)18周岁及以上居民的吸烟行为,包括吸烟率?现在吸烟率?重型吸烟率?平均吸烟量等进行描述性分析并对数据进行多元Logistic 回归分析,探讨我国城乡居民吸烟行为影响因素?结果:我国18周岁及以上居民吸烟率为31.06%,现在吸烟率为27.65%,男女现在吸烟率分别为 54.25%和3.44%,男性高于女性?吸烟者开始吸烟年龄中位数为 20 岁,现在吸烟者日均吸烟中位数为 20 支?Logistic 逐步回归分析显示,性别(OR=0.039,95%CI:0.033~0.046)?文化程度(OR=0.797,95%CI:0.738~0.861)?饮酒(OR=2.406,95%CI:2.138~2.709)和家庭人均年收入(OR=0.870,95%CI:0.786~0.964)是吸烟的相关影响因素,在以医生或教师?未婚和70岁以上年龄组为对照时,职业?婚姻状况和年龄亦是吸烟的影响因素?结论:我国城乡居民的吸烟率依旧很高,烟草控制仍然面临着巨大的挑战,应采取有针对性的措施加强控烟 工作?     

Trends in hospital admissions and mortality from asthma and chronic obstructive pulmonary disease in Australia, 1993-2003

OBJECTIVE: To examine evolving changes in asthma and chronic obstructive pulmonary disease (COPD) in South Australia and Australia as a whole from the perspective of hospital admissions, ventilatory support and mortality data. DESIGN: Retrospective analyses, for the period 1993-2003, of hospital separations data from the Australian Institute of Health and Welfare and the Integrated South Australian Activity Collection, and mortality data from the Australian Bureau of Statistics and South Australian hospital morbidity collection. MAIN OUTCOME MEASURES: Hospital separations, ventilatory support episodes, mortality rates, burden-of-disease rankings. RESULTS: Between 1993 and 2003, in SA and nationally, hospital separations for asthma declined but separations for COPD increased significantly. Falling mortality rates from asthma in both men and women, and from COPD in men, contrast with increasing rates of COPD-related hospitalisation and mortality in women. CONCLUSIONS: Hospital admissions and mortality associated with asthma have fallen. Admission rates for COPD are declining for men, but there is no indication that admission rates for women have reached a peak. There is a need for higher prioritisation of COPD, including policies to reduce smoking in women, and medical practice initiatives to support primary and secondary prevention, pulmonary rehabilitation and appropriate drug therapies.     

上海农村慢性阻塞性肺病研究综合报告

1987～1989年,在上海农村社区对7255人分两批进行横断面调查,发现慢性支气管炎患病率为6.04％和1.15％ ,哮喘为0.52％,慢性阻塞性肺功能障碍为7.15％。冬季一个月内平均每人门诊求治0.43次。每次门诊平均医疗费用为23.89元。COPD的主要危险因素包括年龄、性别、吸烟习惯和接触农业粉尘等。针对可干预的危险因素,对患者进行健康教育。经随访研究6个月,发现对健康教育依从的百分率升高。     

Prevalence of asthma and hay fever in England and Wales

The results concerned with the prevalence of asthma and hay fever in the large surveys of morbidity in general practice in 1970-1 and 1981-2 were compared. In data standardised for age the prevalence of asthma in men increased from 11.6 to 20.5 people consulting per 1000 population (p less than 0.001) and in women from 8.8 to 15.9 per 1000 population (p less than 0.001). Similar increases were also evident in data analysed from the 19 practices contributing to both surveys. The prevalence of asthma increased in each age group examined. Increases of similar magnitude were reported for hay fever--the prevalence in men increased from 10.8 to 19.8 people consulting per 1000 population (p less than 0.001) and in women from 10.3 to 19.7 per 1000 population (p less than 0.001) and occurred in all age groups. The prevalence of acute bronchitis was reduced significantly in the age group 5-14 and increased among the elderly. The prevalence of chronic bronchitis was reduced substantially in 1981-2. The reported increased prevalence of both asthma and hay fever represented a real increase and was not accounted for by changes in diagnostic preference. Only in the age group 5-14 was there any likelihood that some of the increased prevalence of asthma might have resulted from a reduction in the prevalence of acute bronchitis.     

卡介菌多糖核酸治疗慢性支气管炎的疗效评价

为了评价卡介菌多糖核酸对慢性咳嗽咳痰病人的疗效,随机双盲地将慢性咳嗽咳痰病人136例分为卡组72例,对照组64例。两组病人严格按照慢性单纯性支气管炎和慢性喘息性支气管炎的诊断规范再分为2个亚组。在卡组病人中用卡介菌多糖核酸0.5mg/d×36d治疗后和对照组对比,结果显示:①卡组:慢单支组总有效率100％,慢喘支组92.68％;对照组:慢单支组91.67％,慢喘支组75％。②慢单支组:明显显效率卡组明显高于对照组(P=0.0001)。③慢喘支组:卡组中明显显效率和显效率均高于对照组(分别为P=0.0226;P=0.0012)。由此可见,卡介菌多糖核酸是治疗慢单支、慢喘支的有效药物,且疗效好,副作用少。     

成都市温江区慢性阻塞性肺疾病患者的肺功能及危险因素调查研究

目的调查成都市温江区稳定期慢性阻塞性肺疾病（COPD）的肺功能及其危险因素。方法对资料完整的1335例COPD患者进行x线正位胸片及/或肺CT、l2导联心电图检查、肺功能检测。所有患者由呼吸专科医生进行面对面危险因素问卷调查。结果 1335例患者中男性825例,女性510例,平均年龄68.9±15.1岁。其中轻度肺功能异常155例、中度456例、重度541例、极重度183例,以中重度为主。115例病人没有慢性咳嗽病史。有35%患者合并慢性肺源性心脏病。本组COPD患者吸烟率为77.0%,生物燃料接触者占30.9%,5.2%COPD患者有家具厂工作史。患者病情知晓率仅为35.8%,吸入药物治疗率为7.1%。结论温江地区COPD患者吸烟率和生物燃料使用率高,是极为重要的危险因素。应该加强对高危人群的肺功能筛查。患者病情知晓率和吸入药物使用率低,治疗严重不规范。     

Plasma homocysteine levels in indigenous Australians

OBJECTIVES: To determine plasma homocysteine levels in indigenous Australians living in urban areas, and the relationship of these levels with other risk factors in this population. DESIGN: Cross-sectional study. SUBJECTS AND SETTING: 365 urban indigenous Australian subjects, 153 men and 212 women, mean (SE) age 42 (1) years, ascertained without regard to history of atherosclerotic disease, in collaboration with community-based health centres in five indigenous communities in south-east Queensland, 1997-1998. MAIN OUTCOME MEASURES: Plasma homocysteine levels, age, sex, smoking history, metformin therapy, history of atherosclerotic vascular disease, serum creatinine level, red cell folate and serum vitamin B12 levels. RESULTS: 89 subjects (24%) had plasma homocysteine levels 15 mumol/L or above. Homocysteine levels were higher in men than in women (men: 14.4 mumol/L; 95% confidence interval [CI], 13.6-15.2; women: 11.9 mumol/L; 95% CI, 11.4-12.5) (P < 0.001); correlated with age (P < 0.001); higher in current smokers (P = 0.02); higher in subjects taking metformin therapy (P = 0.007); and higher in subjects with a history of atherosclerotic vascular disease (P < 0.001). Homocysteine levels were also correlated with serum levels of creatinine (P < 0.001), red cell folate (P < 0.001), and vitamin B12 (P < 0.001). CONCLUSIONS: These data indicate that the high plasma levels of homocysteine of Australian indigenous subjects are associated with a history of vascular disease, and correlated with, among other things, smoking, and folate and vitamin B12 nutritional deficiency. These are potentially reversible risk factors, and our data suggest that focusing public health initiatives on these issues may reduce the high prevalence of cardiovascular disease in the Australian indigenous population.     

Design and descriptive characteristics of the GHRAS: the Greek Health Randomized Aging Study.

BACKGROUND: The "GHRAS" study is aimed at investigating the interactions among socioeconomic, lifestyle, dietary, psychological, and biochemical factors determining the health status of elderly Greeks. The design and baseline sociodemographic, clinical, and dietary characteristics of the participants are presented here. MATERIAL/METHODS: A total of 782 elderly (>60 years of age) Greeks were randomly recruited in Athens. Standardized anthropometric, biochemical, and clinical procedures and extensive questionnaires were used to assess health parameters and lifestyle factors. RESULTS: A high prevalence of hypercholesterolemia was found in both men and women (78.7% vs. 90.1%, p<0.001) as well as hypertension (81.3% vs. 71.8, p=0.005). Obesity was found in 43.6% of all participants and 42.7% was overweight. Elderly women demonstrated higher mean BMI values than the men (30.2+/-5.0 vs. 28.7+/-4.0, p<0.001). Only 13.4% of all subjects reported current smoking. The majority of the women (77.5%) had never smoked, while most of the men (53.4%) were former smokers. The women appeared more physically active and less adherent to the Mediterranean diet than the men. 36.2% of the women and 21.0% of the men had mild to severe depressive symptoms (p<0.001), while 28.4% of the women and 25.4% of the men had cognitive decline (p=0.430). A history of cardiovascular disease was present in 19.9% and diabetes in 13.9% of all participants. CONCLUSIONS: The prevalence of morbidity risk factors in this population is high. Further investigation is required, including the interaction of compromising factors, to clarify their impact on the health status of the elderly.     

慢性阻塞性肺疾病和支气管哮喘患者血浆及痰液P物质的测定

OBJECTIVE: To investigate the role of substance P (SP) in chronic obstructive pulmonary disease (COPD) or asthma. METHOD: Plasma and sputum samples were obtained from 26 COPD patients and 20 asthmatic patients as well as 12 healthy subjects for measurement of SP content. RESULTS: Patients with COPD had significantly higher levels of SP in the plasma (7.9+/-2.6 pmol/L) and sputum (53.8+/-12.5 pmol/L) than the healthy subjects (3.6+/-1.7 pmol/L and 6.2+/-2.3 pmol/L, respectively, P<0.01). The asthmatic patients also had significantly higher SP levels (8.3+/-3.1 pmol/L and 46.9+/-10.2 pmol/L, respectively) than the healthy subjects, but there was no significant difference between COPD and asthmatic patients (P>0.05). CONCLUSION: SP may be involved in the airway inflammation process in COPD and asthma.     

Prevalence and determinants of self-reported chronic bronchitis among women in rural Central India

Background

Chronic respiratory conditions are increasingly becoming a cause of health concern with India attributing 11% of its mortality due to non-communicable diseases to chronic respiratory conditions. Chronic bronchitis and asthma take a large toll in terms of morbidity. Lesser number of studies have mentioned their counts of these conditions affecting women in rural area and therefore the present study was conducted with the objectives of determining the prevalence and correlates of chronic obstructive pulmonary diseases (COPD) in an area of a primary health centre in rural central India.

Methods

A cross-sectional study was conducted in 24 villages of the study area. Women aged 40 years or more were interviewed using the IUATLD questionnaire. Chronic bronchitis was measured by using the standard criteria for chronic bronchitis, that is, “Presence of cough with expectoration for more than 3 months in a year for the past two or more years”.

Results

Prevalence of chronic bronchitis among women was found to be 2.7%. Factors like older age, presence of a cattle shed within house premises, storage of fertilizers inside house, history of allergy, past history of pulmonary tuberculosis emerged as significant correlates of chronic bronchitis.

Conclusions

The present study provides an insight into the prevalence of chronic bronchitis among rural women exposed to several epidemiological determinants and an opportunity to address the modifiable risk factors.     

苏北农村地区居民高血压病知晓率服药率和控制率调查

目的调查连云港市赣榆、东海二县乡镇居民的高血压病知晓率、服药率和控制率（＂三率＂）,为制定有关卫生政策、更好地开展慢性非传染性疾病（慢病）防控工作提供依据;同时,评估一项正在进行的预防脑卒中综合干预临床研究对以上＂三率＂的影响。方法选择赣榆县、东海县农村社区45～75周岁居民作为调查对象,体检和问卷相结合,进行高血压病＂三率＂的调查,并比较参与临床研究的乡镇（干预乡镇）与未参与临床研究的乡镇（非干预乡镇）＂三率＂的差异。结果本研究共调查4 618人,其中高血压病患者2 784人,调查人群高血压病＂三率＂分别为64.7%、44.7%和7.3%。干预乡镇与非干预乡镇比较,其高血压病知晓率（67.9%vs 62.0%,OR=1.3,P=0.001）、服药率（48.1%vs 41.8%,OR=1.3,P=0.000 9）、控制率（8.8%vs 6.1%,OR=1.5,P=0.006 7）均有提高,且对年龄、性别和地区（县）校正后结果仍成立。结论调查人群高血压病知晓率、服药率显著高于＂九五＂期间我国中年人群的平均水平,控制率略高于＂九五＂平均水平。目前进行的脑卒中预防综合干预研究提高了参与乡镇的高血压病＂三率＂。