肾血管平滑肌脂肪瘤合并肾内动脉瘤一例

病例 女,47岁.因1周前健康体检时行B超检查发现左肾占位性病变而入院.平素健康,无腹胀、腹痛,无腰痛,无尿频、尿急、尿痛,无畏寒、发热,无肉眼血尿、脓尿.查体:T 36.2℃,P 72次/min,R 18次/min,BP 120/80 mmHg,双肾区无饱满,无叩击痛.双侧输尿管走行区无压痛.实验室检查:外周血WBC 12.2 × 109/L、中性粒细胞7.5 × 109/L;肝肾功能正常.     

儿童罕见慢性肉芽肿病影像学表现一例

患者 男,12岁.因咳嗽伴间断发热1个月入院.体检:右面部可见湿疹样皮疹,大小约1.5 cm×1.5 cm,右小腿背侧可见约1 cm×1 cm大小结痂,未见出血点.实验室检查:白细胞计数8.75×109/L,中性粒细胞0.797,淋巴细胞0.184,C-反应蛋白(CRP) 38 mg/L,肺炎支原体IgM(+),柯萨奇IgG(+).胸部CT平扫示双肺散在斑片状实变影(图1A).治疗1周后临床症状好转出院.次年患儿再因发热3天伴咳嗽入院.实验室检查:血红蛋白100 g/L,白细胞计数12.79×109/L,中性粒细胞0.714,淋巴细胞0.241,单核细胞3.7％,CRP 46 rng/L,72 h结核菌素试验(PPD)6 cm×6cm×2 cm.真菌实验(+).肝功能115 U/L.     

脾脏窦岸细胞血管瘤1例

1病例报告患者女,63岁。因影像学检查提示脾脏占位2个月余入院。既往无特殊病史。查体:无明显阳性体征。实验室检查:白细胞4.1×109/L,中性粒细胞0.64,红细胞3.81×1012/L,血红蛋白11.4g/L,血小板176×109/L。血液肿瘤标志物均正常。上腹部CT平扫加增强扫描:肝脏正常大小,各叶比例均在正常范围,外形轮廓规整,肝实质内未见异常密度改变。脾内可见副     

纵隔结核脓肿累及前胸壁1例

患者男,21岁,发现前胸壁肿物3个月,伴疼痛1周.体检:T 36.7℃,无发热及盗汗,浅表淋巴结未触及肿大,胸骨角上方触及直径2.2 cm大小包块,质韧,界限不清,压痛明显.实验室检查:白细胞6×109/L,中性粒细胞0.80,单核细胞增高,血沉52 mm/h.X线胸片未见异常.     

慢粒进展为慢粒伴骨髓纤维化后急淋变1例实验室指标分析

病人,男,33岁.体检发现白细胞增高.于2003年9月22日入院.查体:浅表淋巴结无肿大,胸骨无压痛,肝肋缘下未及,脾肋缘下9 cm.RBC 2.7×1012/L,Hb 90g/L,WBC 160.0×109/L,BPC 276×109/L, 白细胞分类:原始粒细胞0.04,中幼粒细胞0.27,晚幼粒细胞0.18,中性杆状核细胞0.20,中性分叶核细胞0.22,嗜酸粒细胞0.02,嗜碱粒细胞0.01.     

颈部滑膜肉瘤1例

患者 男,42岁.于2年前无意中发现左颈后部皮肤下黄豆大小无痛性包块,逐渐长大.体检:左侧颈后部触及一大小约6.0 cm×5.0 cm的包块,无压痛,质韧、边界不清,活动度较差,周围皮温稍高,软组织无破溃.实验室检查:白细胞5.63×109/L,中性粒细胞3.21×109/L,中性粒细胞比例57.0％,淋巴细胞比例26.1％,单核细胞比例10.7％,嗜酸细胞比例5.0％,嗜碱细胞比例1.2％.     

读片窗

患者男,12岁.无诱因持续性发热40天,体温曾达38℃,服抗炎药物未见好转.发现右颈部淋巴结肿大26天,偶有触痛.查体:右上颈约5.0cm×6.0cm大小肿物,质软,右下颈有0.5cm×0.5cm淋巴结3枚,可活动.脾可触及.实验室检查:周围血象白细胞计数3.6×109/L,淋巴细胞0.52,中性粒细胞0.39.血沉37.8mm/h.     

输卵管积脓误诊卵巢囊肿蒂扭转2例

病例 患者1,女,38岁,下腹痛3 d入院.入院前3 d无诱因出现下腹疼痛,活动后加重,无恶心、呕吐、腹泻等不适.外院检查血常规:WBC 13.9×109/L,N 81.4%;B超检查盆腔积液3.8 cm.给予静脉抗生素输液治疗2 d,腹痛稍好转.我院检查B超:右附件包块7.0 cm×6.0 cm×6.0 cm;血常规:WBC 10.5×109/L,N 86.4%.查体:T 36.5℃,全腹软,右下腹轻压痛,无反跳痛.妇科检查:阴道通畅,分泌物多,淡黄色,无味,宫颈轻度糜烂,举痛、后穹窿触痛明显,宫体正常大小,右附件区可触及一6.0 cm×5.0 cm×5.0 cm包块,囊性,不活动,压痛明显.     

原发下腔静脉平滑肌肉瘤1例

患者女,53岁,因上腹部胀痛半年,加重1个月入院.查体:右上腹轻度压痛,无肌紧张及反跳痛,未触及异常包块,移动性浊音阴性,无腹壁静脉曲张,无下肢肿胀.常规实验室检查:白细胞15.4×109/L,中性粒细胞13.95×109/L,余无异常.肾图:双肾功能大致正常.     

肠伤寒致肠套叠1例

1病例报告患者女,10岁。因阵发性右下腹疼痛4h入院。查体:体温36·3℃,血压98/66mmHg。急性病容,自主强迫坐位,腹壁稍硬,右下腹可触及一4cm×3cm的包块,质硬、活动度差、边界不清、有明显压痛,肝、脾无肿大。实验室检查:白细胞11·2×109/L,中性粒细胞0·77。B超示右下腹非均质     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.