中耳癌的研究进展

中耳癌是发生在中耳和乳突区的少见恶性肿瘤,病理上以鳞癌最常见,恶性程度高.早期临床症状多不典型,常与慢性中耳炎的表现相似,不易早期发现,诊断主要依靠影像学检查及病理检查.近年来国际上对中耳癌的治疗策略不一,以外科手术为主的综合治疗是本病主要的治疗措施,且预后较差.     

外耳道癌及中耳癌52例临床分析

原发性外耳道癌及中耳癌是全身较罕见的恶性肿瘤。现将我院从1988年2月～1993年2月收治的52例外耳道癌及中耳癌病例的临床资料及随访结果分析报告如下:材料与方法一　临床资料　全组52例患者,男性39例,女性13例,年龄26～78岁,平均年龄542岁,其中50岁以上35例,占全组总人数...     

55例外耳道及中耳癌的临床及疗效分析

外耳道及中耳癌是一种较少见的恶性肿瘤 ,国内外文献报道不多 ,发病率约占头颈部恶性肿瘤的 0 .7%～ 1.6 %。我院自 1976年— 1992年共收治外耳道及中耳癌患者 5 5例 ,现在就其临床资料分析如下。1　资料与方法1.1　一般资料本组病例中男 4 2例 ,女 13例 ,男女之比为 3.2 3∶ 1,年龄最大 76岁 ,最小 2岁 ,平均 5 3岁。全组均经病理证实 ,其中鳞癌 37例 ,基底细胞癌 3例 ,腺样囊性癌 9例 ,乳头状瘤恶变 6例。肿瘤发生在外耳道 2 6例 ,中耳 2 4例 ,外耳道及中耳均有 5例。据 1985年 Stell和 Mcormick分期标准 ,本组病例 T1 期 18例 ,T2 期30…     

中耳癌诊治15例报告

 本文分析了15例中耳癌的临床资料。结果显示：中耳癌的预后差与其病期较晚治疗困难有关。早期诊断和手术加放射疗法的综合治疗可能提高生存率。慢性化脓性中耳炎可能是诱发中耳癌的原因之一，预防中耳炎可能减少中耳癌的发病率。     

中耳癌14例治疗报告

对１４例中耳癌患者的临床资料进行了总结和分析。均采用综合治疗，即手术加术前、后放疗，其疗效与单纯放疗相比，发现综合治疗并无提高，而且手术并发症多。因此，建议对中耳癌患者首选放射治疗。手术适应于乳突根治术或放疗失败的晚期病例。颞骨切除后行面、副神经吻合，可大致保持面部肌肉对称，借助动肩以维持面肌运动，可有效的防止患侧面肌萎缩。对颈部淋巴结阴性患者无必要进行预防性清扫或放射治疗。     

64例外耳道及中耳癌放疗疗效分析

 我们对1977年～1989年间收治的术前，术后和单纯放疗的64例外耳道及中耳癌病例进行回顾性分析．本组病例的特点为高龄者多、临床晚期病例多，原发病灶受累部位多．总的五、十年生存率分别为50%和35.3%．单纯放疗，术前和术后放疗的五年生存率分别为44%、66.7%和55.6%．本文讨论了不同的治疗方法和治疗失败的主要原因．作者认为外耳道及中耳癌单纯放疗的最适宜剂量为60～70GY/6～7周，术后放疗为50～70GY/5～7周．     

中耳癌 20例临床分析

中耳癌较少见，易误诊。提高对本瘤的认识，做到及时诊断治疗，对提高治愈率和患者生活质量十分重要。我科１９７４～１９９４年收治中耳癌２０例，现报告分析如下。１材料与方法１．１临床资料 年龄与性别：２０例中，男性１５例，女性５例；男女之比为３：１；年龄３８～６４岁（平均４９岁），其中４０～６０岁者１６例，占本组患者总数的８０．０％。 症状与体征：耳道溢脓２０例次，流血性分泌物１４例次，耳痛１１例次，面神经麻痹 ９例次，听力减退１８例次，耳鸣及眩晕４例次，头痛２例次，开口困难１例次。颈部淋巴结肿大，经组织…     

膀胱小细胞癌的研究进展

 膀胱小细胞癌（Small—cell carcinoma of the urinary bladder，SCBC），是泌尿系肿瘤中一种比较罕见的恶性肿瘤。但因其在临床和流行病学特征与膀胱移行细胞癌存在着极大的相似性，而生物学行为却呈高度恶性，进展快、转移早、预后差，如今已越来越受到肿瘤科及泌尿外科医生的重视。因此，本文将对膀胱小细胞癌的新近研究做一综述。     

Endoscopic transcanal middle ear surgery

The advantages and limitations of the microscope have defined postauricular access as the surgical intervention of choice for the treatment of diseases of the middle ear. The wide-angle view provided by the endoscope enables transcanal access to the tympanic cavity, and its otherwise difficult-to-reach extensions: The attic, sinus tympani, facial recess, and hypotympanum. These areas are the primary sites of disease and surgical failure to cure. The endoscope also allows an all encompassing view of the three main elements in tympanoplasty surgery: The ear canal, tympanic membrane, and the tympanic ring. This report is a summary of the author’s two 17 years of experience with the use of transcanal operative endoscopy as the primary approach to the management of middle ear disease.     

The results of radiotherapy of cancer of the middle ear

Between 1971-1986 29 patients with cancer of the middle ear were treated with radiotherapy. Eighteen patients were treated with curative intent, 17 after incomplete surgery and 1 after biopsy only. Eleven patients were irradiated palliatively. In curative radiotherapy wedge pair technique or mixed photon-electron beam was used with a tumor dose of 60 Gy in 24-30 fractions. The probability of 5-year disease-free survival (DFS) is 53% for patients treated with curative intent. There is a correlation between extent of disease and survival. Excessive early reaction was observed in two patients, and late bone necrosis in one. Mean survival in the palliatively irradiated group was 3.6 months.     

Lymphomas of the middle ear

Lymphomatous overgrowths of the middle ear are extremely rare. A case of lymphoma which presented as an aural polyp with facial paralysis in a child aged two years is being reported here.     

Scleroma of the middle ear

A case of Scleroma presenting in the middle car is reported     

Adenoids and middle ear pressure

A group of100 children were studied who underwent adenoidectomy and or tonsillectomy because of either upper respiratory tract infection or recurrent otitis media, the mean age of the group was7 years6 months. The mean pre-operative middle ear pressure (MEP) was ?89.3 mm H₂O, two months postoperatively it was ?32.4 mm H₂O, a highly significant improvement. The size of the adenoids had a nearly significant effect on the pre-operative MEP. The difference is highly significant in large vs small adenoids. In8 children where tonsillectomy was done alone, as adenoidectomy was done earlier had to effect on MEP. There was no change of MEP in children undergoing adenoidectomy with or without nasal allergy.