共查询到20条相似文献,搜索用时 15 毫秒
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Reiter N El-Shabrawi L Leinweber B Berghold A Aberer E 《Journal of the American Academy of Dermatology》2011,65(1):15-22; quiz 23-4
Because calcinosis cutis is a rare syndrome, there is a notable lack of controlled clinical trials on its treatment. The efficacy of calcinosis treatment has only been reported in single cases or small case series. No treatment has been generally accepted as standard therapy, although various treatments have been reported to be beneficial, including warfarin, bisphosphonates, minocycline, ceftriaxone, diltiazem, aluminium hydroxide, probenecid, intralesional corticosteroids, intravenous immunoglobulin, curettage, surgical excision, carbon dioxide laser, and extracorporeal shock wave lithotripsy. 相似文献
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A 22-year-old male patient presented with multiple swellings over elbows and knees and a sinus over the right elbow discharging chalky white material. Skin biopsy of the swelling demonstrated calcium deposition in dermis and subcutis. There was no evidence of connective tissue disorder or abnormal mineral metabolism. Hence it was concluded as idiopathic calcinosis cutis and is reported for its interesting presentation. 相似文献
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Z Ogretmen A Akay C Bicakci HC Bicakci 《Journal of the European Academy of Dermatology and Venereology》2002,16(6):621-624
We report the case of a 49-year-old female who complained of hardening of the skin, with onset about 1.5 years before presentation. The laboratory data showed normal biochemistry profile. Routine haematochemical examinations showed slight anaemia, an increased erythrocyte sedimentation rate and negative rheumatological markers. Calcium excretion in a 24-h urine sample was normal, but the phosphate excretion was slightly low. The clinical diagnosis was verified by soft tissue ultrasound examination showing subcutaneous calcifications. X-ray examination of bones evidenced no abnormal calcification. Mammography revealed deep seated bilateral reticular calcifications, even in the axillary region. Histological examination showed calcinosis cutis. On these grounds, the diagnosis of idiopathic universal calcinosis cutis was made. The authors describe the clinical and histological picture and discuss the laboratory findings. 相似文献
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Fernandez-Flores A 《Acta dermatovenerologica Croatica : ADC》2011,19(1):43-50
The most widely accepted classification of calcinosis cutis is reviewed and several aspects of it are examined. The main point of our criticism is that entities from different groups overlap. Also, the classification mixes etiopathogenic criteria with morphological or semiologic ones. Moreover, the role of the dermatopathologist is limited many times, since only generic information under the diagnosis "calcinosis cutis" is given to the clinician. Taking these into account, we introduce a possible morphological classification of calcinosis cutis, based on the pattern of the cutaneous deposits. 相似文献
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We report an 8-year-old boy who developed dystrophic calcinosis cutis that occurred following trauma. Multiple abrasions were observed in the inguinal folds after a soccer game. Subsequently, multiple papules with soft centers and white particles appeared in the same area. A biopsy specimen showed calcinosis cutis with transepidermal elimination of calcium. The causes of the underlying tissue damage associated with dystrophic calcinosis are discussed. 相似文献
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We report a case of calcinosis cutis in a 41-year-old man developing after liver transplantation at sites where no intravenous calcium had been administered. The cutaneous lesions developed on his right upper arm 10-days post-transplantation. The patient had received calcium chloride solution intravenously after surgery. We excluded other causes of ectopic calcification such as hyperparathyroidism, renal failure, and extravasation of calcium chloride. 相似文献
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Arthur Wiskemann 《Archives of dermatological research》1955,199(5):507-512
Zusammenfassung Calcinosis cutis universalis und Poikilodermie wurden nebeneinander bei einer bandförmigen Sklerodermie und bei einer Dermatomyositis gesehen. Es handelt sich um atrophische Endzustände bei verschiedenartigen Krankheiten, nicht um selbständige Krankheitseinheiten. 相似文献
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Velez NF Callen JP Vleugels RA 《Journal of the American Academy of Dermatology》2012,66(6):1004-5; author reply 1005
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Dermatomyositis is an idiopathic inflammatory myopathy with characteristic cutaneous manifestations. We describe a case of a 55-year-old woman with dermatomyositis who presented with dystrophic calcinosis resistant to medical treatment. 相似文献
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Calcinosis cutis is a chronic condition involving insoluble calcified deposits of the skin and subcutaneous tissue. It is commonly associated with autoimmune connective tissue diseases and can be a source of pain and functional disability. The likelihood of developing calcinosis varies among the autoimmune connective tissue diseases, with systemic sclerosis and dermatomyositis being the most commonly associated. Identification of therapy for this challenging disorder has been hampered by a paucity of large controlled trials. Although there is no uniformly effective treatment for calcinosis cutis, several surgical and medical therapies have demonstrated varying degrees of benefit in the treatment of calcinosis, including surgical excision, laser therapy, extracorporeal shock wave lithotripsy, diltiazem, minocycline, colchicine, and topical sodium thiosulfate, along with others. Recommendations for the diagnosis and therapy of calcinosis cutis in patients with autoimmune connective tissue diseases are discussed. 相似文献