Combining information in different color-coding mechanisms to facilitate visual search

An earlier experiment using a yes-no procedure with a search accuracy task [A.L. Nagy, G. Thomas, Distractor heterogeneity, attention, and color in visual search tasks, Vision Research, 43 (2003) 1541-1552] showed that observers could combine information in different cardinal color mechanisms to facilitate search performance. In the experiments reported here we attempted to replicate these results with a forced-choice procedure and tested three different models of the manner in which information in different feature coding mechanisms is combined. One model was a linear summing model in which signals in different mechanisms are linearly summed in a mechanism under the control of attention. The summed signals are used to guide attention to likely targets. The second model was a nonlinear selection model in which signals in one mechanism are used to select stimuli for attention. A decision is then based on signals generated by the selected stimuli in a mechanism other than the one that is used for selection. The third model was the linear separability model, which suggests that the chromaticity of the target stimulus must be separated from the chromaticities of the distractor stimuli by a straight line in a chromaticity diagram for efficient search. Results favored the nonlinear selection model over the linear summing model and the linear separability model.     

Sleep and rest facilitate implicit memory in a visual search task

Several forms of learning have been demonstrated to show improvements with sleep. Based on rodent models, it has been suggested that replay of waking events in the hippocampus during sleep may underlie memory consolidation in humans. However, behavioral data for the role of sleep in human hippocampal-related memory have been inconsistent. To further investigate the role of sleep in hippocampal-mediated learning, we tested subjects in two sessions of a contextual cueing paradigm, a form of hippocampus-dependent implicit learning, separated by intervals of sleep, active wake, or carefully controlled quiet rest. Participants completed a visual search task, and unbeknownst to them, some search displays were occasionally repeated in the experiment. Contextual cueing was revealed by faster search speed on repeated trials (Old) than unrepeated ones (New), even though subjects were unaware of the trial repetition. Notably, performance in a second testing session was equivalent for participants who underwent quiet resting, daytime sleep, or nocturnal sleep between the two sessions. These four groups showed equivalent transfer of learning from Session 1. Notably, learning of New configurations in Session 2 was absent in the active wake group, but was equally strong among the other three groups. These results indicate that this form of hippocampal learning is independent of sleep, and vulnerable to proactive interference during active wake. They prompt a reevaluation of the hippocampal replay hypothesis as a general model of sleep-dependent learning.     

Meaning and expected surfaces combine to guide attention during visual search in scenes

How do spatial constraints and meaningful scene regions interact to control overt attention during visual search for objects in real-world scenes? To answer this question, we combined novel surface maps of the likely locations of target objects with maps of the spatial distribution of scene semantic content. The surface maps captured likely target surfaces as continuous probabilities. Meaning was represented by meaning maps highlighting the distribution of semantic content in local scene regions. Attention was indexed by eye movements during the search for target objects that varied in the likelihood they would appear on specific surfaces. The interaction between surface maps and meaning maps was analyzed to test whether fixations were directed to meaningful scene regions on target-related surfaces. Overall, meaningful scene regions were more likely to be fixated if they appeared on target-related surfaces than if they appeared on target-unrelated surfaces. These findings suggest that the visual system prioritizes meaningful scene regions on target-related surfaces during visual search in scenes.     

Inhibition of return is not a foraging facilitator in saccadic search and free viewing

The ability to search and scan the environment effectively is a prerequisite for spatial behavior. A longstanding theory proposes that inhibition of previously attended loci (Inhibition of return; IOR) serves to facilitate exploration by increasing the likelihood to inspect new areas instead of returning to locations that have been inspected before. In this eye movement study we tested whether we could find evidence in favor of this hypothesis. Here we report that IOR does occur during search and free viewing, because we found increased fixation times preceding return saccades (eye movements that return to previously fixated locations). Meanwhile we observed no influence of IOR on the search strategy. Rather than the predicted low number we found many return saccades. Therefore, IOR does not serve as a foraging facilitator in saccadic search and free viewing. We hypothesize that IOR is an intrinsic aspect of shifting attention and gaze direction and furthermore that it is not always advantageous to prevent return saccades.     

Between-object and within-object saccade programming in a visual search task

The role of the perceptual organization of the visual display on eye movement control was examined in two experiments using a task where a two-saccade sequence was directed toward either a single elongated object or three separate shorter objects. In the first experiment, we examined the consequences for the second saccade of a small displacement of the whole display during the first saccade. We found that between-object saccades compensated for the displacement to aim for a target position on the new object whereas within-object saccades did not show compensation but were coded as a fixed motor vector applied irrespective of wherever the preceding saccade landed. In the second experiment, we extended the paradigm to examine saccades performed in different directions. The results suggest that the within-object and between-object saccade distinction is an essential feature of saccadic planning.     

The proximity-fixation-disparity curve and the preferred viewing distance at a visual display as an indicator of near vision fatigue.

PURPOSE: This laboratory study investigates the relation between measures of fixation disparity (FD) (and other optometric measures) and near vision fatigue at a computer workstation. METHODS: Young adult subjects with normal binocular vision performed three blocks of a visual task of 30 min each. In Block A, the viewing distance was 100 cm, as a reference without near vision. In Block B, the viewing distance of 50 cm induced a defined near vision load. In Block C, subjects were free to choose a comfortable viewing distance. This preferred viewing distance was used as an indicator of near vision fatigue because subjects adopting longer viewing distances in Block C had more near vision fatigue at 50 cm in Block B. RESULTS: Subjects with preferred viewing distances longer than average (63 cm) had steeper slopes of FD as a function of viewing distance (100-30 cm), as shown by discriminant analyses. CONCLUSIONS: Thus, this steep proximity-FD curve indicates a weak disparity vergence system that may cause near vision fatigue. This may explain why some young adults prefer longer viewing distances at the computer workstation.     

Hiding the Rabbit: Using a genetic algorithm to investigate shape guidance in visual search

During visual search, attention is guided by specific features, including shape. Our understanding of shape guidance is limited to specific attributes (closures and line terminations) that do not fully explain the richness of preattentive shape processing. We used a novel genetic algorithm method to explore shape space and to stimulate hypotheses about shape guidance. Initially, observers searched for targets among 12 random distractors defined, in radial frequency space, by the amplitude and phase of 10 radial frequencies. Reaction time (RT) was the measure of “fitness.” To evolve toward an easier search task, distractors with faster RTs survived to the next generation, “mated,” and produced offspring (new distractors for the next generation of search). To evolve a harder search, surviving distractors were those yielding longer RTs. Within eight generations of evolution, the method succeeds in producing visual searches either harder or easier than the starting search. In radial frequency space, easy distractors evolve amplitude × frequency spectra that are dissimilar to the target, whereas hard distractors evolve spectra that are more similar to the target. This method also works with naturally shaped targets (e.g., rabbit silhouettes). Interestingly, the most inefficient distractors featured a combination of a body and ear distractors that did not resemble the rabbit (visually or in spectrum). Adding extra ears to these distractors did not impact the search spectrally and instead made it easier to confirm a rabbit, once it was found. In general, these experiments show that shapes that are clearly distinct when attended are similar to each other preattentively.     

Orientation-specific contextual modulation of the fMRI BOLD response to luminance and chromatic gratings in human visual cortex

The responses of orientation-selective neurons in primate visual cortex can be profoundly affected by the presence and orientation of stimuli falling outside the classical receptive field. Our perception of the orientation of a line or grating also depends upon the context in which it is presented. For example, the perceived orientation of a grating embedded in a surround tends to be repelled from the predominant orientation of the surround. Here, we used fMRI to investigate the basis of orientation-specific surround effects in five functionally-defined regions of visual cortex: V1, V2, V3, V3A/LO1 and hV4. Test stimuli were luminance-modulated and isoluminant gratings that produced responses similar in magnitude. Less BOLD activation was evident in response to gratings with parallel versus orthogonal surrounds across all the regions of visual cortex investigated. When an isoluminant test grating was surrounded by a luminance-modulated inducer, the degree of orientation-specific contextual modulation was no larger for extrastriate areas than for V1, suggesting that the observed effects might originate entirely in V1. However, more orientation-specific modulation was evident in extrastriate cortex when both test and inducer were luminance-modulated gratings than when the test was isoluminant; this difference was significant in area V3. We suggest that the pattern of results in extrastriate cortex may reflect a refinement of the orientation-selectivity of surround suppression specific to the colour of the surround or, alternatively, processes underlying the segmentation of test and inducer by spatial phase or orientation when no colour cue is available.     

Fixation-related potentials in visual search: a combined EEG and eye tracking study

We report a study of concurrent eye movements and electroencephalographic (EEG) recordings while subjects freely explored a search array looking for hidden targets. We describe a sequence of fixation-event related potentials (fERPs) that unfolds during ～ 400 ms following each fixation. This sequence highly resembles the event-related responses in a replay experiment, in which subjects kept fixation while a sequence of images occurred around the fovea simulating the spatial and temporal patterns during the free viewing experiment. Similar responses were also observed in a second control experiment where the appearance of stimuli was controlled by the experimenters and presented at the center of the screen. We also observed a relatively early component (～150 ms) that distinguished between targets and distractors only in the freeviewing condition. We present a novel approach to match the critical properties of two conditions (targets/distractors), which can be readily adapted to other paradigms to investigate EEG components during free eye-movements.     

Head and eye movements and the role of memory limitations in a visual search paradigm

The image information guiding visual behavior is acquired and maintained in an interplay of gaze shifts and visual short-term memory (VSTM). If storage capacity of VSTM is exhausted, gaze shifts can be used to regain information not currently represented in memory. By varying the separation between relevant image regions, S. Inamdar and M. Pomplun (2003) demonstrated a trade-off between VSTM storage and gaze shifts, which were performed as pure eye movements, that is, without a head movement component. Here we extend this paradigm to larger gaze shifts involving both eye and head movements. We use a comparative visual search paradigm with two relevant image regions and region separation as independent variable. Image regions were defined by two cupboards displaying colored geometrical objects in roughly equal arrangements. Subjects were asked to find differences in the arrangement of the objects in the two cupboards. Cupboard separation was varied between 30 degrees and 120 degrees . Images were presented with two projectors on a 150 degrees x 70 degrees curved screen. Head and eye movements were simultaneously recorded with an ART head tracker and an ASL mobile eye tracker, respectively. In the large separation conditions, the number of gaze shifts between the two cupboards was reduced, while fixation duration increased. Furthermore, the head movement proportions negatively correlated with the number of gaze shifts and positively correlated with fixation duration. We conclude that the visual system uses increased VSTM involvement to avoid gaze movements and in particular movements of the head. Scan path analysis revealed two subject-specific strategies (encode left, compare right, and vice versa), which were consistently used in all separation conditions.     

Patients with AMD and a large absolute central scotoma can be trained successfully to use eccentric viewing,as demonstrated in a scanning laser ophthalmoscope

Twenty patients with age-related macular degeneration, an absolute central scotoma and a mean visual acuity of 0.04 (20/475) were studied. A scanning laser ophthalmoscope (SLO) was used for microperimetry and determination of preferred retinal locus, often located to the left of the retinal lesion (corresponding to a location to the left of the visual field scotoma), which is considered unfavorable for reading. All 20 patients were trained to use a new and more favorable retinal locus for reading, above (or occasionally below) the retinal lesion (corresponding to a location below or above the visual field scotoma), first by reading scrolled text under simultaneous fixation monitoring and instruction in the SLO and then by reading printed text, using high magnification (mean 14.3x). For the 18 patients who learned to use eccentric viewing, reading speed with adequate magnification prior to training was 9.0+/-5.8 words/min. With training (mean 5.2 hours), it increased significantly (p<0.001) to 68.3+/-19.4 words per min. Training of eccentric reading has thus proved to be very successful.     

Combining vernier acuity and visual backward masking as a sensitive test for visual temporal deficits in aging research

Performance in many everyday situations slows down when age increases. The causes of slowing down may be found on any stage of information processing. Here, we show that the combination of a vernier acuity task and the shine-through backward masking paradigm is a good paradigm to determine temporal processing deficits. The paradigm is relatively robust to optical blur and unlikely affected by motor dysfunctions. Strong masking deficits are found from an age of about 50 years on.     

Cytology as a guide to the presence of chlamydial inclusions in Giemsa-stained conjunctival smears in severe endemic trachoma.

Microscopical examination of 927 Giemsa-stained conjunctival smears from children with chronic trachoma in southern Tunisia showed 93 (10 per cent.) with typical trachoma (chlamydial) inclusions in epithelial cells. The accompanying cytological features were a useful indicator for inclusions. Inclusions were found only in slides with numerous polymorphonuclear neutrophils (PMNs) and separation of the epithelial cells. When these two features alone were present, 3 per cent. of the smears were inclusion-positive; when many lymphocytes were present also, 25 per cent. were inclusion positive; when other cytological features (plasma cells, macrophages, blastoid, and stem cells) were present as well, 70 per cent. of the smears were inclusion-positive. The occurrence of these sets of cytological features can be a useful guide for selecting smears for intensive examination for chlamydial inclusions. Immunofluorescent (FA) staining and Giemsa staining of 527 pairs of matched smears detected trachoma agent in 67 (13 per cent.); in thirty by both methods, in thirteen by Giemsa staining alone, and in 24 by FA alone. The examination of Giemsa-stained smears for chlamydial inclusions is a useful technique for the diagnosis of trachoma or inclusion conjunctivitis by laboratories that do not have the specialized facilities for the identification of these chlamydial infections by the technically more complex procedures of immunofluorescent staining or isolation in embryonated eggs or tissue cultures.     

Electrical activity in visual cortex associated with combined auditory and visual stimulation in temporal sequences known to be associated with a visual illusion

When a subject views a visual stimulus paired with a brief click, a second click occurring approximately 80 ms later produces the hallucination of a second visual stimulus. We have used combinations of visual and sound stimuli to evoke cortical activity and have recorded the associated event-related potentials. We have recorded EPs in a conventional manner, and have calculated from multichannel recordings the Laplacian derivations to determine if the currents were generated in primary visual cortex. Clicks alone do not cause significant activity in V1, but if paired with pattern stimulation, modify the evoked potential. The timing of this extra activity almost certainly excludes "feed back" activation from higher centres, and can most simply be explained if sound-activated thalamo-cortical input can rapidly produce extra activity in 'primed' visual cortex. This finding has general implications for cortical function, for the generation of the hallucination and for 'blindsight'.