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化瘀复元颗粒剂的制备与临床应用 总被引:2,自引:0,他引:2
目的:通过对化瘀复元颗粒剂进行质量控制及临床疗效观察,检验处方组成及其制备工艺的合理性。方法:建立了该颗粒剂的质量标准,对服用本颗粒剂62例癌痛患者进行了追踪观察。结果:总的疼痛缓解率为93.5%。结论:本制剂疗效可靠,服用方便。 相似文献
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目的制备金茵颗粒剂,确定该制剂质量标准,考察该制剂的稳定性,观察临床疗效。方法采用部分药材水煎浓缩、喷雾干燥后,与糖粉、熊胆粉混合制粒,干燥的综合制备工艺;采用加速稳定性试验和室温留样稳定性试验,观察金茵颗粒剂粒度、溶化性、性状和水分变化,并用HPLC测定制剂中绿原酸含量,从而研究该制剂稳定性,与胆益宁片对比观察临床疗效。结果在高温、强光条件下药物稳定性较好,在高湿条件下不稳定,加速试验与18个月室温留样试验中金茵颗粒剂性状、水分及绿原酸含量测定结果显示稳定性好;临床观察实验中,金茵颗粒剂总有效率为86%。结论金茵颗粒剂在18个月内稳定性较好,与胆益宁片疗效比较,金茵颗粒剂疗效较好,是治疗胆囊炎的有效药物。 相似文献
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目的探讨桑通颗粒的制备工艺、质量控制方法及临床应用。方法将方中川贝母、水牛角粉碎,其余药材煎煮浓缩,加入辅料制备颗粒剂;观察其对慢性阻塞性肺疾病急性加重期的临床疗效。结果总有效率治疗组为89.47%,对照组为70.83%,两组有显著性差异(P〈0.05)。结论制剂质量可控,疗效可靠,服用方便。 相似文献
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目的:制备疱疹消搽剂治疗颜面部单纯疱疹、生殖器单纯疱疹、带状疱疹,观察临床疗效和不良反应。方法:筛选了黄芩等中药制备成搽剂,与3%阿昔洛韦霜作对照临床观察。结果:治疗组有效率为94.9%,对照组有效率79.0%.疗效差异有显著性(P<0.05),治疗期间未见不良反应发生。结论:本制剂处方合理,制法简单,是治疗上述病毒感染性皮肤病安全、有效的制剂。 相似文献
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目的:研制六味乳痛消颗粒剂,并观察其临床疗效.方法:根据临床经验自拟处方并制备六味乳痛消颗粒剂,并治疗乳腺增生症患者50例.结果:制备方法简便可行,治疗总有效率96.0%.结论:本制剂组方合理,临床疗效满意. 相似文献
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目的 介绍一种医院制剂清肺止嗽颗粒的制备工艺、质量控制标准及临床疗效.方法 根据清热解毒、消炎化痰的原则拟定了处方,并制备成颗粒剂.结果 本院自制的清肺止嗽颗粒剂符合《中国药典》颗粒剂的各项有关规定,主要有效成分可用薄层色谱法鉴别确认;临床于上呼吸道感染者,治愈率可达40.00%,好转率达39.17%,总有效率为79.17%,暂未出现临床不良反应.结论 清肺止嗽颗粒组方科学,制备方法简便,质量有效可控,临床效果良好,无不良反应,具备推广开发应用价值. 相似文献
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苍耳子软膏治疗生殖器疱疹的临床观察 总被引:2,自引:0,他引:2
目的:观察苍耳子软膏治疗生殖器疱疹的临床疗效。方法:外用苍耳子软膏治疗由HSV-Ⅱ(单纯疱疹Ⅱ型病毒)所致生殖器疱疹62例,并与阿昔洛韦软膏治疗64例进行疗效比较。结果:苍耳子软膏组总有效率91·94%,阿昔洛韦软膏组总有效率92·22%,2组间疗效比较无显著性差异(P>0·05)。结论:苍耳子软膏可用于治疗生殖器疱疹,其疗效与阿昔洛韦软膏相当。 相似文献
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C P Conlon 《British medical bulletin》1988,44(1):101-114
The HIV epidemic probably arose in Africa at about the same time as in the West, and there is a significant seroprevalence of HIV in the central African region. However, the epidemiology and clinical course of AIDS are different in Africa and in the West. In Africa males are infected as often as females, and the commonest means of transmission is heterosexual intercourse. Many HIV-infected people are symptomless, but many others present with or progress to generalized lymphadenopathy, pruritus, herpes zoster, herpes simplex, cellulitis, and oral candidiasis. The World Health Organization developed a clinical case-definition of AIDS in Africa, which was found to have a specificity of 90% and a sensitivity of 59% when tested in Zaire. The Kaposi's sarcoma seen in African AIDS patients is more aggressive than that seen in the West and is often visceral. Gastrointestinal AIDS (the "slim" disease) with weight loss and diarrhea is common in Africa, as are oral and esophageal candidiasis. In Africa Pneumocystis carinii pneumonia is rare, but pulmonary tuberculosis is common. Neurological manifestations include cerebral toxoplasmosis, cytomegalovirus infection, headache, and terminal encephalopathy. About 60% of infants born to seropositive women are infected and die within the 1st year of life. Lack of drugs and diagnostic facilities make both diagnosis and treatment of opportunistic infections difficult. 相似文献
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养血清脑颗粒治疗失眠的临床观察 总被引:2,自引:0,他引:2
陈金鸥 《中国医院用药评价与分析》2007,7(6):461-462
目的:观察养血清脑颗粒治疗失眠的临床疗效。方法:入组76例失眠患者,给予养血清脑颗粒每日3次,每次1袋治疗,4周为1疗程,治疗2个疗程。观察治疗前及治疗第4周、8周末的情况,用阿森斯失眠量表评定疗效。结果:治疗4周后失眠和认知功能障碍总有效率分别为63.15%和53.95%,治疗8周后失眠和认知功能障碍总有效率分别为89.47%和85.53%。结论:多数患者服药8周后失眠及认知功能障碍均有缓解。 相似文献
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目的 :观察黄精多糖制剂奥得福尔治疗生殖器疱疹的临床疗效。方法 :采用随机、开放、平行、对照的方法 ,应用奥得福尔喷剂(WS)和奥得福尔霜剂 (WC) ,同时以阿昔洛韦软膏 (AO)作为对照 ,治疗性病门诊确诊的生殖器疱疹患者5组各80例 (共400例 ) ,观察临床疗效及其不良反应。结果 :WS开放组的总有效率为92 50 % ,平行组为91 25 % ;WC开放组的总有效率为93 75 % ,平行组为91 25 %。WS组 (开放组 +平行组 )在3天内起效的达64 38 % ,7天内起效的达91 88 % ;WC组 (开放组 +平行组 )在3天内起效的达68 13 % ,7天内起效的达91 88 % ;两者起效时间平均比AO组提前2天。所有病例均无严重不良反应 ,患者依从性好。结论 :奥得福尔治疗生殖器疱疹起效快、疗程短、疗效显著 ,且应用方便、安全 相似文献
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The objective of this article is to review and evaluate risks and benefits associated with the use of acyclovir in the treatment and prophylaxis of common manifestations of herpes simplex virus (HSV) infections in immunocompetent and immunocompromised patients. Information was found through a MEDLINE search using keywords: herpes simplex virus, genital herpes, herpes labialis, acyclovir and acyclovir. Selected articles were randomised, double-blind, placebo-controlled, clinical trials. 30 such trials involving 3364 persons were evaluated. All articles were reviewed by the authors and the data were extracted and summarised. In both immunocompetent and immunocompromised hosts, acyclovir therapy demonstrated a high degree of clinical efficacy. None of the studies reported statistically significant differences between acyclovir and placebo for mild or major adverse events. This evaluation found that acyclovir is both effective and well tolerated for treatment and prophylaxis of genital, oral and mucocutaneous HSV infections in immunocompetent and immunocompromised patients. In most clinical scenarios. the benefit of acyclovir exceeded any risks by a comfortable margin. The availability of acyclovir as a generic preparation further improves the benefit to cost ratio. 相似文献
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替硝唑棒剂的制备及临床疗效 总被引:2,自引:0,他引:2
目的 :研究替硝唑棒剂的制备及质量控制方法 ,并观察其临床疗效。方法 :采用紫外分光光度法测定替硝唑的含量 ,并对45例牙周病患者进行临床疗效观察。结果 :替硝唑的平均回收率为99 06 % ,RSD=1 03 % ;对牙周病显效率为93 33 %。结论 :替硝唑棒剂的制备工艺合理 ,性质稳定 ,质控方法可行 ;疗效可靠 ,有推广应用价值 相似文献