Acute anuric bilateral ureteral obstruction in malignant lymphoma

Two cases of bilateral ureteral obstruction in malignant lymphoma are reported. In one case, primary infiltration of the ureters by Hodgkin's disease was demonstrated, while in the other the obstruction was due to ureteral compression by enlarged lymph nodes. The diagnostic procedures and the management of such cases are discussed.     

Lymphographic classification of malignant lymphoma.

In an attempt to raise the diagnostic accuracy of lymphography in malignant lymphoma, especially in early stages, the disease were radiographically classified into 3 groups such as atypical, typical and advanced group mainly based on the lymphographic findings. The findings showed characteristic features corresponding to the stages of the disease. Atypical group showed the following findings: small filling defects, increased number of lymph node and visualization of the marginal sinus. The findings were regarded as those of early stages of malignant lymphoma.     

Primary malignant melanoma of right colon.

We report a 62-year-old lady who presented with abdominal lump and neurological deficit. Investigations showed ascending colon mass, subcutaneous nodule and right parietal lobe lesion. Histology and immunohistochemistry were suggestive of malignant melanoma. The search for primary site was negative.     

Granulocyte colony-stimulating factor-producing malignant lymphoma.

A 71-year-old woman with leukocytosis was admitted for treatment of malignant lymphoma. During the clinical course, neutrophilia of unknown origin occurred in parallel with the progression of the malignant lymphoma. The supernatant of lymphoma tissue culture contained a high titer of granulocyte colony-stimulating factor (G-CSF), and lymphoma cells were positive when immunohistochemically stained by anti-G-CSF antibody. Western blot analysis and mouse colony assay of the supernatant also confirmed that the lymphoma produced G-CSF.     

Distribution of malignant polyps in the colon

The purpose of this study was to investigate whether the distribution of malignant polyps of the colon is the same as the distribution of all polyps in general. A consecutive and unselected series of 1226 endoscopically removed polyps was analyzed; the analysis indicated a strong preponderance of malignant polyps to be located in the left side of the colon. Ninety-five per cent of the malignant polyps were taken distal to the splenic flexure, whereas that segment of the colon produced only 72 per cent of all of the polyps in general. It is not possible to determine the reason for this from the present study, but the importance of removing these polypoid lesions continues to be emphasized by these data.     

Pneumothorax following cytotoxic chemotherapy in malignant lymphoma.

Pneumothorax occurring as a complication of the antitumor effect of cytotoxic chemotherapy has been reported in occasional cases of a variety of tumors. Its occurrence in malignant lymphoma has not been reported heretofore. In this report, we describe two cases of this complication in patients with malignant lymphoma and discuss the possible pathophysiologic mechanisms involved. Because pulmonary involvement with the tumor was found in both cases, pneumothorax could be attributed to the anti-tumor effect of cytotoxic agents on underlying lung involvement in patients with malignant lymphoma.     

Non-Hodgkin's lymphoma of the colon and ulcerative colitis. Case report.

The association between ulcerative colitis and lymphoma is rare. The authors report the case of a 54-year old white man who presented a clinical picture and radiological and colonoscopic findings suggesting the diagnosis of idiopathic ulcerative colitis. Histopathological and immunohistochemical studies of tissue specimens obtained at autopsy led to the diagnosis of non-Hodgkin's B-cell T-cell-rich lymphoma throughout the colon. Possible relations between ulcerative colitis and gastrointestinal lymphoma are discussed.     

Acute perforations of the colon

Summary A retrospective study of acute perforations of the colon is presented. Sites, causes, morbidity, mortality, and treatment are discussed. Comparison with several large series is made. Read at the meeting of the American Society of Colon and Rectal Surgeons, New Orleans, Louisiana, May 2 to 6, 1976.     

A case of primary malignant lymphoma of the liver.

Primary lymphoma of the liver is extremely rare, and its preoperative or premortem diagnosis is still difficult. The author report here a case of primary malignant lymphoma of the liver diagnosed on a basis of ultrasonically guided biopsy of the tumor. A 51-year-old man was found to have a relatively large tumor in the right lobe of the liver as well as elevated serum LDH with abnormal isoenzyme pattern. Immunohistological studies of both biopsy and postmortem specimens of the tumor indicated T cell malignant lymphoma of the liver. The present case appears to be the second case of T cell origin of the disease.