A 10-year prospective study of ITI dental implants placed in the posterior region. I: Clinical and radiographic results

OBJECTIVES: To evaluate the long-term fixture success rate, crestal bone loss and peri-implant soft tissue parameters around ITI dental implants placed in the posterior region of partially edentulous patients. MATERIAL AND METHODS: A total of 192 ITI dental implants were consecutively placed in premolars and molars of 83 partially edentulous patients admitted for treatment at Geneva Dental School. All implants were restored by means of ceramic-to-metal fused fixed partial dentures and single crowns. Patients were followed as part of a prospective longitudinal study focusing on implant success. Surgical, radiographic and clinical variables were collected at the 1-year recall after implant placement and at the most recent clinical evaluation. RESULTS: The mean observation time was 6 years (range 5-10 years). Four implants failed, yielding a 10-year cumulative survival rate of 97.9%. The mean annual crestal bone loss was -0.04+/-0.2 mm. Hollow-cylinder implants displayed more crestal bone loss (-0.13+/-0.24 mm) than hollow-screw implants (-0.02+/-0.19 mm; P=0.032). Clinical parameters such as age, gender, implant length and bone quality did not affect crestal bone levels. Increase in recession depth (P=0.025) and attachment level (P=0.011) were significantly associated with crestal bone loss. CONCLUSIONS: ITI dental implants placed in the posterior jaw demonstrate excellent long-term clinical success. Hollow-cylinder implants seem to display a higher risk for crestal bone loss. Recession depth and attachment levels appear to be good clinical indicators of peri-implant bone loss.     

A 5-year prospective study on small diameter screw-shaped oral implants

Alveloar ridges of limited dimensions could preclude the placement of dental implants of the regular dimension. Smaller diameter implants - narrow platform (NP) implants were commercially available to address this issue. The aim of the study was to determine the 5-year clinical performance of 3.3 mm diameter NP implants. Twenty-three machined screw-shaped NP implants were placed in nine patients (six males; three females) between 18 and 70 years of age. Clinical and radiographic examinations were performed annually for 5 years. Recognized implant success criteria was used. The criteria were based on the mean marginal alveolar bone loss, the placement of prosthesis of satisfactory appearance, and the absence of implant mobility, peri-implant radiolucency, pain, discomfort or infection. One implant failed at abutment connection. The remaining 22 implants were restored and functioned successfully according to the criteria. The mean marginal alveolar bone loss during the first year was 0.41 +/- 0.17 mm. The mean marginal alveolar bone loss between the second and fifth year was 0.03 +/- 0.06 mm. The success rate of NP implants according to a well-established set of criteria was 96%.     

A comparison of hydroxyapatite (HA) -coated threaded,HA-coated cylindric,and titanium threaded endosseous dental implants

PURPOSE: The purpose of this study was to compare the success of hydroxyapatite (HA) -coated and machined titanium (Ti) implants in a 5-year randomized, controlled clinical trial conducted at 2 centers. MATERIALS AND METHODS: Each of 120 edentulous patients received HA-coated threaded, HA-coated cylindric, and machined Ti threaded implants in a randomized design using 5 or 6 implants. Digital radiographs allowed for yearly measurements of bone loss. Calibrated clinicians also measured mobility, Gingival Index, Plaque Index, probing depth, and recession. A Kaplan-Meier analysis was used to compare the proportion of ailing implants (defined as less than 2 mm of alveolar bone loss over 5 years) for each type of implant design. The criteria employed to assess implant outcome included the need for successful implants to lose less than 2 mm of bone support over the 5 years following placement of the prosthesis. RESULTS: This analysis revealed that 95.2% of machined Ti threaded implants and 97.92% of HA-coated threaded implants were successful, while 99.0% of HA-coated cylindric implants experienced less than 2 mm of bone loss (P < .06). DISCUSSION: All types of implants placed in this study had success rates above 95%. CONCLUSION: Over 5 years, the success rate tended to favor HA-coated implants.     

A retrospective radiographic analysis of bone loss following placement of TiO2 grit-blasted implants in the posterior maxilla and mandible

PURPOSE: Cortical bone is a determinant of implant esthetics and may contribute to the biomechanical integrity of the implant-supported prosthesis. Historically, approximately 1.0 to 1.5 mm of bone loss has occurred immediately following second-stage surgery and implant loading. Recent consideration of implant design suggests that surface topography may affect crestal bone responses at the implant interface. The aim of this retrospective study of 102 implants in 48 subjects supporting posterior fixed partial dentures was to radiographically define the behavior of crestal bone at TiO2 grit-blasted implants following surgical placement and subsequent loading in the posterior maxilla and mandible. MATERIALS AND METHODS: The crestal bone position relative to the implant reference point (junction of the crestal bevel with the TiO2 grit-blasted surface) was evaluated at implant placement, at abutment placement, and 6 to 36 months following restoration, with an average recall period of 2.3 years. The implant position and dimension were recorded. A single investigator using 7x magnification assessed all radiographs. RESULTS: Crestal bone loss from the time of implant placement up to 36 months following restoration ranged from 0.0 to 2.1 mm. Of the 102 implants, 14 implants showed greater than 1.0 mm of crestal bone loss. They were not clustered at any particular tooth position. Eighty of the implants showed less than 0.5 mm of radiographically measured bone loss. Mean crestal bone loss was 0.36 mm (+/- 0.6 mm). Averages of 0.57 and 0.24 mm loss were shown for 3.5- and 4.0-mm-diameter implants, respectively (P < .051). Bone gain was seen at several 4.0-mm-diameter implants. DISCUSSION: This retrospective evaluation indicates that the radiographically measured bone loss may be expected to be less than 1 mm following placement and loading of TiO2 grit-blasted implants. The close approximation of bone with the implant/abutment interface suggests the attenuation of any microgap-induced bone loss. Additional reasons for crestal bone maintenance may include factors attributed to implant surface roughness and loading along a tapered implant/abutment interface. CONCLUSIONS: Several clinical advantages for maintaining crestal bone at implants supporting posterior prostheses can be identified.     

软组织瓣早期裂开或穿孔对种植体颈缘部骨组织的影响

放射线性片评估种植手术后软件组织瓣早开裂或穿孔对种植体周边缘骨吸收的影响。方法：１７例种植患者,植入的３２颗两段式骨内种植体,其中１７颗出现软组织瓣早期裂开或穿孔,导致种植体早期暴露。根据种植体入当天及种植Ⅱ期手术（安装愈合基台）前的Ｘ线片（根尖片）,测量出种植体颈部边缘骨高度的变化。结果：早期暴露的种植体均产生明显吸收,近中平均１．９５ｍｍ,远中平均２．１５ｍｍ;而正常愈合种植体（非裂开）骨变化     

Clinical outcome of Screw Vent implants. A 7-year prospective follow-up study

The clinical results of 85 Screw Vent implants are described with respect to 7-year success, including radiographically detectable bone loss, survival and prosthetic quality. The 1-year results of the same material have been reported previously (De Bruyn et al. 1992). Implants were considered as successful when they were meeting with the success criteria proposed by the European Academy for Periodontology. From the 85 implants originally installed, 16 failed during the 7-year interval (18.8%), 6 were unaccounted for (7%), 21 (24.7%) did not meet the success criteria yet survived and 42 implants (49.4%) were successful. The success rate was 65.2% for the mandibular and 43.5% for the maxillary implants. Implant failures were irrespective of implant length, smoking habits, prosthetic quality or oral hygiene level. From 24 patients with a corresponding number of 60 implants, radiographs were available for bone loss analysis. The mean bone loss after 7 years was 2.92 mm (range -0.5 to 6.3) 18 out of 60 examined implants (30%) showed unacceptable radiological bone loss beyond the critical value of 2.7 mm. Implant material analysis and histomorphometric analysis of a retrieved implant are discussed. In the present clinical study, the Screw Vent implant system does not meet the success criteria proposed by the European Academy for Periodontology. The ongoing bone loss increases the risk for future implant failures and peri-implant disease.     

A 5-year follow-up study on one-stage implants inserted concomitantly with localized alveolar ridge augmentation

The aim of this study was to evaluate the success of one-stage implants placed at the time of alveolar bone augmentation using simultaneous guided bone regeneration technique with a collagen barrier membrane in patients suffering from insufficient bone width. Seventeen patients were treated with 20 one-stage OSTEOFIX (Oulu, Finland) implants using simultaneous guided bone regeneration technique. Dehiscence defects were filled by bovine bone mineral Bio-Oss and covered with collagen membrane. Clinical and radiographic parameters of the peri-implant conditions were assessed at the moment of prosthesis placement and at 1- and 5-year follow-ups. Diagnostic dehiscence defect measurements after implant placement showed that the mean vertical defect varied from 3.8 mm to 10.0 mm. At the moment of prosthesis placement and at 1- and 5-year follow-ups all implants were stable, painless and without biological complications. Clinical and radiographic parameters of the peri-implant conditions remained stable during follow-up. The cumulative implant survival rate was 100% after the 5-year observation period and the success rate for all pooled implants was 90%. The present study showed predictable treatment outcomes recorded after 5 years of function for one-stage OSTEOFIX (Oulu, Finland) oral implants placed simultaneously with guided bone regeneration using collagen membrane and deproteinized bovine bone mineral.     

Nine- to fourteen-year follow-up of implant treatment. Part II: presence of peri-implant lesions

OBJECTIVES: The aim of this study was to analyse the proportions of peri-implant lesions at implants after 9-14 years of function. MATERIAL AND METHODS: Two hundred and ninety-four patients underwent implant therapy during the years 1988-1992 in Kristianstad County. These individuals were recalled to the speciality clinic 1 and 5 years after placement of the suprastructure. Between 2000 and 2002, 218 patients with 999 implants were examined clinically and radiographically. RESULTS: Forty-eight per cent of the implants had probing depth > or =4 mm and bleeding on probing (peri-implant mucositis). In 20.4% of the implants, the bone level was located 3.1 mm apical to the implant shoulder. Progressive bone loss (> or =1.8 mm) during the observation period was found in 7.7% of the implants. Peri-implantitis defined as bone loss > or =1.8 mm compared with 1-year data (the apical border of the bony defect located at or apical to the third thread, i.e. a minimum of 3.1 mm apical to the implant shoulder), combined with bleeding on probing and or pus, were diagnosed among 16% of the patients and 6.6% of the implants. CONCLUSION: After 10 years in use without systematic supportive treatment, peri-implant lesions is a common clinical entity adjacent to titanium implants.     

Three-year evaluation of single-tooth implants restored 3 weeks after 1-stage surgery

PURPOSE: The possibility of expediting dental implant therapy by early or immediate loading protocols requires long-term clinical investigation. The aim of this prospective cohort trial was to determine the 3-year implant success rate and prosthesis complications associated with functional loading 3 weeks after 1-stage placement of Astra Tech single-tooth implants replacing maxillary anterior teeth. A secondary objective was to determine peri-implant tissue responses at these implants. MATERIALS AND METHODS: The peri-implant bone and mucosal conditions of 43 implants in 39 subjects were radiographically and clinically measured 3 years after implant placement. RESULTS: Of the 48 patients originally treated, 39 patients and 43 implants were examined at the 3-year time point. Three of 54 implants failed within the first year. No additional failures were recorded since the 12-month reporting period. Peri-implant bone levels were stable for the 3-year period following implant placement. The change in marginal bone levels after 3 years was 0.42 +/- 0.59 mm. Papilla growth was measured at 1 and 3 years (0.61 +/- 0.95 mm and 0.74 +/- 0.79 mm, respectively). The buccal peri-implant tissue dimensions at the gingival zenith also increased at 1 and 3 years (0.34 +/- 0.94 mm and 0.51 +/- 1.42 mm, respectively). No abutment screw loosening or fracture occurred. DISCUSSION AND CONCLUSIONS: Early loading of endosseous dental implants placed in healed ridges offers select benefits to clinicians and their patients.     

A 5-year longitudinal study of the clinical effectiveness of ITI solid-screw implants in the treatment of mandibular edentulism

PURPOSE: The aim of this longitudinal study was to gain 5-year clinical documentation of the 1-stage surgical technique in connection with ITI solid-screw implants used in the edentulous mandible. MATERIALS AND METHODS: One hundred patients with totally edentulous mandibles were treated with bar-retained overdentures supported by a total of 340 consecutively placed ITI solid-screw implants. The patients were followed at annual intervals for at least 5 years to evaluate implant success, longitudinal reactions of the peri-implant hard and soft tissues, and incidences of biologic and mechanical complications. RESULTS: During the trial period, a total of 4 implants failed, all prior to loading, and 51 implants were lost to follow-up, resulting in a cumulative survival rate of 98.8% after 5 years of functional service. The success analysis included additional strictly defined events (either "first occurrence of marginal bone loss > or = 4 mm" or "first occurrence of pocket depth > or = 4 mm" and "first occurrence of crevicular fluid flow rate > or = 2.5 mm) and resulted in a cumulative 5-year success rate of 95.7%. The median marginal bone loss experienced between implant placement and prosthetic treatment was 0.5 mm, followed by an annual bone level change of 0.1 mm for the functional period of 5 years. The increasing incidence of remarkable plaque deposits from 19% to 50% represented the difficulties of the patients in maintaining a high level of oral hygiene, particularly for the lingual surfaces. Sulcus Bleeding Index, probing depth, attachment level, and crevicular fluid flow rate were used to describe the health of the peri-implant soft tissues and remained almost within acceptable standards. DISCUSSION: Survival and success rates of implants, amount of marginal bone loss, and periodontal indices of peri-implant soft tissues were consistent with those reported in the literature regarding implants with the submerged healing concept. CONCLUSION: With a cumulative survival rate of 98.8%, a cumulative success rate of 95.7%, and a median marginal bone loss of 0.5 mm during the healing period, followed by an annual rate of 0.1 mm after loading, non-submerged ITI solid-screw implants confirm the good clinical outcome of implant-supported treatment concepts for the rehabilitation of totally edentulous patients in a medium-term perspective.     

A 10-year prospective clinical and radiographic study of one-stage dental implants

OBJECTIVE: The purpose of this prospective study was to evaluate one-stage dental implants clinically and radiographically after 10 years in function. MATERIAL AND METHODS: Twenty-five patients with a total of 68 implants [46 hollow screws (HS) and 22 hollow cylinders (HC)] who previously participated in 5-year prospective clinical study returned for a 10-year follow-up. For each patient, informed consent was obtained, medical and dental history was reviewed and soft and hard tissue conditions were evaluated using the modified plaque index, modified sulcus bleeding index, probing depth, suppuration, attachment level, distance from the implant crown margin to the coronal border of the peri-implant mucosa keratinized mucosa and periapical radiographs to calculate crestal bone-level changes. RESULTS: As expected, the mean crestal bone-level changes were the greatest in the first year following restoration placement, while only minimal changes were noticed in the subsequent years. HC implants showed a statistically significant higher mean crestal bone loss when compared with HS implants at year 10. Gender was also statistically significantly related to the mean crestal bone loss at years 1, 3, 5 and 10, with male subjects exhibiting more bone loss than female subjects. However, age and peri-implant soft tissue parameters showed low levels of correlation with the mean crestal bone-level changes, and proved to be weak predictors for the mean crestal bone loss at years 5 and 10. CONCLUSIONS: This study confirms that the mean crestal bone loss rates of the HS and HC implants are well within the clinically acceptable parameters. In addition, some of the clinical parameters could be used to assess and predict future crestal bone loss.     

The use of reduced healing times on ITI implants with a sandblasted and acid-etched (SLA) surface: early results from clinical trials on ITI SLA implants

ITI dental implants are available with two bone-anchoring surfaces, a titanium plasma-sprayed (TPS) surface, and a recently introduced sandblasted and acid-etched (SLA) surface. Cell culture and animal tests demonstrate that the SLA surface stimulates bone cell differentiation and protein production, has large amounts of bone-to-implant contact, and results in large removal torque values in functional testing of the bone contact. As a result of these studies, a prospective human clinical trial was initiated to determine whether the 4.1 mm diameter SLA ITI solid screw implants could be predictably and safely restored as early as six weeks after implant placement surgery. The protocol restricted the use of the reduced healing time to a) healthy patients with sufficient bone volume to surround the implant, and b) those patients who had good bone quality (classes I-III) at the implant recipient site. Patients with poorer bone quality (class IV) did not have restorations until 12 weeks after implant placement. The clinical trial is an ongoing multicenter trial, with six centers in four countries, and with follow-up over five years. The primary outcome variable was abutment placement with a 35 Ncm force, with no countertorque and no pain or rotation of the implant. A secondary outcome was implant success, as defined by no mobility, no persistent pain or infection, and no peri-implant radiolucency. To date, 110 patients with 326 implants have completed the one-year post-loading recall visit, while 47 patients with 138 implants have completed the two-year recall. Three implants were lost prior to abutment connection. Prosthetic restoration was commenced after shortened healing times on 307 implants. The success rate for these implants, as judged by abutment placement, was 99.3% (with an average healing time of 49 days). Life table analyses demonstrated an implant success rate of 99.1%, both for 329 implants at one year and for 138 implants at two years. In the 24-month period after restoration, no implant losses were reported for the 138 implants. These results demonstrate that, under defined conditions, solid screw ITI implants with an SLA endosseous surface can be restored after approximately six weeks of healing with a high predictability of success, defined by abutment placement at 35 Ncm without countertorque, and with subsequent implant success rates of greater than 99% two years after restoration.     

��ض����ܲ���ĥ��������λ�㱣������Ȼ���Ϻ���ֲ����Ч���Ա��о�

??Objective    To observe the clinical efficacy of implant treatment following alveolar ridge preservation in the molar extraction sockets with severe periodontitis and compare it with the natural healing control group. Methods    Ten patients with a total of 13 molar extraction sockets with severe periodontitis receiving implant placement following alveolar ridge preservation??6 patients??6 tooth??or natural healing??5 patients??7 tooth??were recruited in Peking University School and Hospital of Stomatology from 2013 to 2016. In a 12-30 months follow-up period??each implant was examined with the following parameters??probing depth??bleeding index??plaque index??papilla index??PI?? and food impaction. Parallel periapical radiographs were taken every 6 months to evaluate the peri-implant marginal bone loss. Success rate was defined using the criteria from Karoussis et al??2004??. Additionally??each patient completed retrospectively a satisfaction questionnaire using Visual Analog Scale ??VAS??. Results    There was a 100% survival rate of implants in both groups. The success rate was around 100% for implants in ridge-preserved sites and around 42.9% for implants in natural healing sites. There were no statistically significant differences in the BI??PLI or PI between two groups except for the PD??P < 0.05??. Marginal bone loss of the implant in both groups at the 12th month after implant loading was <1 mm. After the first year of service??annual marginal bone loss did not exceed 0.2 mm in ridge preservation group??the mesial and distal sites were??0.03 ± 0.16??mm and??0.05 ± 0.10??mm on average. All the patients were satisfied with the implant with VAS ≥ 85. There were no statistically significant differences between PI and food impaction. Conclusion    Implant placement at ridge-preserved molar sites with severe periodontitis is a predictable procedure resulting in very high survival rates and higher success rates compared to implant placement in natural healing sites.     

Stability of Contour Augmentation and Esthetic Outcomes of Implant‐Supported Single Crowns in the Esthetic Zone: 3‐Year Results of a Prospective Study With Early Implant Placement Postextraction

Background: Early implant placement is one of the treatment options after tooth extraction. Implant surgery is performed after a healing period of 4 to 8 weeks and combined with a simultaneous contour augmentation using the guided bone regeneration technique to rebuild stable esthetic facial hard‐ and soft‐tissue contours. Methods: In this prospective study, 20 patients were treated with an implant‐born single crown and followed for 3 years. Clinical, radiologic, and esthetic parameters were recorded to assess treatment outcomes. Results: At the 3‐year examination, all 20 implants were successfully integrated, demonstrating ankylotic stability and healthy peri‐implant soft tissues as documented by standard clinical parameters. Esthetic outcomes were assessed by the pink esthetic score (PES) and white esthetic score (WES) and confirmed pleasing results overall. WES values were slightly superior to PES values. Periapical radiographs showed minimal crestal bone loss around used bone‐level implants with a mean bone loss of 0.18 mm at 3 years. Only two implants revealed bone loss between 0.5 and 1.0 mm. One of these implants had minor mucosal recession <1.0 mm. Conclusions: This prospective study evaluates the concept of early implant placement and demonstrated successful tissue integration for all 20 implants and stable bone‐crest levels around implant–abutment interfaces according to the platform‐switching concept. The midterm 3‐year follow‐up revealed pleasing esthetic outcomes and stable facial soft tissues. The risk of mucosal recession was low, with only one patient showing minor recession of the facial mucosa. These encouraging results need to be confirmed with a 5‐year follow‐up examination.     

Evaluation of Clinical Outcomes and Bone Loss around Titanium Implants with Oxidized Surface: Six‐Year Follow‐Up Results from a Prospective Case Series Study

Purpose: The aim of this prospective study was to assess long‐term clinical outcomes and peri‐implant bone level changes around oxidized implants supporting partial fixed rehabilitations. Materials and Methods: Twenty‐two partially edentulous patients were included in the study. A total of 33 fixed rehabilitations were placed, supported by 54 titanium implants with oxidized microtextured surface. Prostheses were delivered after 3 and 6 months of implant placement in the mandible and maxilla, respectively. Patients were scheduled for follow‐up at 6 and 12 months and then yearly. At each follow‐up, plaque level and bleeding scores were assessed and periapical radiographs were taken. The main outcomes were prosthesis success, implant survival, implant success, and marginal bone level change. Results: Three patients were excluded from the study because they did not attend the 1‐year follow‐up. Nineteen patients, accounting for 49 implants, were followed for at least 6 years after prosthesis delivery. The mean follow‐up duration was 81.8 months (range 75–96 months). One mandibular single‐tooth implant failed after 1 year in a smoker woman. Cumulative implant survival and success at 6 years were 98.0% and 95.9%, respectively. Prosthesis success was 96.7%. The mean peri‐implant bone loss at 6 years was 0.76 ± 0.47 mm. Not significantly (p = .75) greater bone loss was found in the maxilla (0.78 ± 0.14 mm, n = 19) as compared with the mandible (0.74 ± 0.59 mm, n = 30). In the maxilla, bone loss was significantly greater around implants supporting partial prostheses as compared with single‐tooth implants (p = .03). Full patient satisfaction was reported. Conclusion: Implants with oxidized microtextured surface may achieve excellent long‐term clinical outcomes in the rehabilitation of partial edentulism.     

Localized ridge augmentation using a micro titanium mesh: a report on 27 implants followed from 1 to 3 vears after functional loading

The present paper describes the clinical and radiographic healing results of 27 implants followed from 1 to 3 years after functional implant loading. Prior to implant placement, alveolar ridges with insufficient bone volume were augmented using autogenous bone grafts and a micro titanium mesh for graft stabilization. After a mean interval of 5.2 months implants were installed. Following an osseointegration period of on average 7.2 months, implants were supplied with suprastructures. The mean loading period for the 27 implants was 21 months. All implants exhibited ankylotic stability and healthy peri‐implant soft tissues. The detailed analysis of clinical parameters (probing depth, level of mucosal margin, attachment level, modified plaque and sulcus bleeding indices) and radiographic measurements (crestal bone level), revealed findings similar to those at implants placed into non‐augmented bone. Peri‐implant bone resorption was calculated to be 1.0 mm for the 1st year after implant loading and 0.1 mm for the following year. Pain, suppuration or semilunar bone defects were absent at all implants. It was concluded that loaded dental implants which have been inserted into an augmented alveolar ridge using autogenous bone grafts and a micro titanium mesh for graft stabilization, demonstrate clinical and radiographic findings similar to those of implants placed into a pristine ridge.     

Behavior of implants in bone grafts or free flaps after tumor resection

The authors compared bone resorption of autogenous bone grafts and revascularized free flaps used for the reconstruction of mandibular continuity defects following resection for tumors, before and after the placement of endosseous implants. Ten patients (group 1) were treated with autogenous bone grafts taken from the fibula or the anterior iliac crest; 8 patients (group 2) were treated with iliac or fibula revascularized flaps. Four to 8 months later, 72 endosseous implants were placed in the reconstructed areas. After a further healing period of 4-6 months, patients were rehabilitated with implant-borne prostheses. The following parameters were evaluated and compared between the two groups: 1) bone resorption of grafts and free flaps before and after implant placement; 2) peri-implant bone resorption mesial and distal to each implant, immediately after prosthetic rehabilitation and then during yearly follow-ups. Bone resorption before implant placement showed mean values of 3.53 mm in group 1, and 0.96 mm in group 2. Peri-implant bone resorption was: 0.49 mm (39 implants) in group 1, and 0.45 mm (30 implants) in group 2, at time of prosthetic rehabilitation; 0.78 mm (39 implants) in group 1, and 0.89 mm (30 implants) in group 2, 12 months after prosthetic load; 1.16 mm (24 implants) in group 1, and 1.02 mm (13 implants) in group 2, 24 months after the prosthetic load. A significant difference in bone resorption before implant placement was found between the two groups, whereas it was not found after implant placement and prosthetic load. The failure rate according to Albrektsson criteria was 4.9% (2/41 implants) in group 1, and was 3.2% (1/31) in group 2.     

A randomized clinical trial to evaluate and compare implants placed in augmented versus non-augmented extraction sockets: 3-year results

Background: The alveolar ridge undergoes reabsorption and atrophy subsequent to tooth removal and thus exhibits a wide range of dimensional changes. Preservation of the alveolar crest after tooth extraction is essential to enhance the surgical site before implant fixture placement. The aim of this randomized clinical study is to investigate and compare the need for additional augmentation procedures at implant insertion, as well as the success rate and marginal bone loss for implants placed in the grafted sites versus those placed in naturally healed sites. Methods: Forty patients with ≥1 hopeless tooth were randomly allocated to: 1) a test group, receiving extraction and grafting corticocancellous porcine bone; and 2) a control group, receiving extraction without any graft. After 7 months of healing, implants were inserted in each of the sites. The implants were submerged and loaded after 4 months with metal–ceramic rehabilitation. The follow‐up included evaluation of implant diameter and length, the need for additional augmentation procedures at implant placement, implant failure, and marginal bone level changes. All patients were followed over a 3‐year period. Results: One implant failed in the control group at the second stage of surgery (6 months after placement); one implant failed in the test group after 2 years of loading. The cumulative implant success rate at the 3‐year follow‐up visit reached 95% for both groups. No statistically significant differences were detected for marginal bone changes between the two groups. Conclusions: It was concluded that implants placed into grafted extraction sockets exhibited a clinical performance similar to implants placed into non‐grafted sites in terms of implant survival and marginal bone loss. However, grafted sites allowed placement of larger implants and required less augmentation procedures at implant placement when compared to naturally healed sites.     

Long-term evaluation of osseointegrated implants placed in sites augmented with sinus floor elevation associated with vertical ridge augmentation: a retrospective study of 38 consecutive implants with 1- to 7-year follow-up

This clinical study retrospectively evaluated, after 1 to 7 years of prosthetic loading, 38 implants consecutively placed in 16 surgical sites, where severe atrophy of the posterior maxilla was treated by combining sinus elevation with the vertical ridge regenerative procedure. Two different surgical techniques were adopted. In seven patients (16 implants), implants were placed at the same stage as the regenerative procedures. In the other seven patients (22 implants), implant placement was performed at second-stage surgery, after 6 to 13 months of submerged membrane healing. Each implant was classified as a success, survival, or failure. The distance between the top of the implant shoulder and the first visible bone-implant contact was assessed radiographically for every implant at the mesial and distal sides. Two membranes became exposed during the healing process (12.5%). In the remaining 14 sites (87.5%), the membrane remained covered for a 6- to 13-month healing period. The survival rate of the implants was 92.1%, whereas the success rate was 76.3%. Three implants (7.9%) failed. A comparison of the implant shoulder-bone-implant contact distances between abutment connection and the last examination showed a mean crestal loss of 1.65 mm at the mesial side and 1.68 mm at the distal side. The bone regenerated vertically by means of sinus floor elevation and vertical ridge augmentation showed the same biologic behavior as native, nonregenerated bone; however, in a few cases, its remodeling pattern seemed to determine slightly higher bone crest resorption.     

Early and immediate loading of titanium implants with fluoride-modified surfaces: results of 5-year prospective study

Objective: Multiple experimental and animal studies have shown that topographic, mechanical and chemical properties of implant surfaces lead to in vivo responses such as increased bone formation, increased bone anchorage and reduced healing time. A fluoride modification of the titanium implant surface also seems to positively influence bone anchorage as compared with unmodified titanium implants. Using implant survival and marginal bone loss as primary outcome parameters, the purpose of the present prospective study was to investigate whether a fluoride modification of the titanium implant surface has positive clinical effects. Materials and methods: The 17 patients included in this study received 49 Astra Tech OsseoSpeed^? implants for various indications in the maxilla and mandible. Implants were either loaded immediately or after a mean healing period of 9.56 weeks. Fifteen patients were followed up clinically including radiographic examination for 5 years. Forty‐two implants were assessed for implant survival, marginal bone loss, surgical and/or prosthetic complications, presence or absence of plaque, signs of inflammation and size of the papilla. Results: Of the original 17 patients, 15 patients were available for the full 60‐month follow‐up. One early implant failure occurred, leading to an implant survival rate of 97%. Radiographic analyses demonstrated stable bone conditions with a mean marginal bone loss of 0.1 mm (SD 0.4 mm, min ?0.7 mm, max 1.7 mm) after 5 years of function. Immediately loaded implants did not show a different mean marginal bone loss as compared with implants that were not loaded immediately. Repeated soft‐tissue examinations revealed healthy conditions in terms of 6.1% plaque and 4.2% of the implants with signs of inflammation at the 5‐year control. Discussion: Implants used in this study had high survival and success rates after 5 years. Marginal bone was well maintained, irrespective of the loading regime. To cite this article:
Mertens C, Steveling HG. Early and immediate loading of titanium implants with fluoride‐modified surfaces: results of 5‐year prospective study.
Clin. Oral Impl. Res. xx , 2011; 000–000.