长脉冲可调脉宽Nd：YAG激光治疗毛细血管瘤124例

目的 探讨长脉冲可调脉宽Nd：YAG激光治疗毛细血管瘤的疗效及影响因素。方法 长脉冲可调脉宽Nd：YAG激光治疗毛细血管瘤患者124例,根据皮损面积、颜色、深浅选择参数,并根据即刻反应调整参数。治疗间隔1个月。结果 135个皮损的治愈率为74.07%,有效率为90.37%。各因素对疗效的影响：皮损面积越小,有效率越高（P < 0.01）,部位及皮损厚度的不同对疗效无影响（均为P > 0.05）。不良反应：术后水疱发生率为8.89%,萎缩性瘢痕发生率为2.96%。结论 长脉冲可调脉宽Nd：YAG激光治疗毛细血管瘤效果好,不良反应小,是治疗毛细血管瘤的有效方法之一。     

Nd:YAG激光治疗尿道内尖锐湿疣的疗效观察

目的评价Nd:YAG激光治疗尿道内尖锐湿疣(CA)的疗效。方法96例尿道内CA患者随机分为治疗组55例,采用Nd:YAG激光治疗;对照组41例,采用CO2激光治疗,两组术后均予卡介菌多糖核酸治疗,比较两组的治愈率及复发率。结果两组一次性治愈率差异有显著性(P<0.05),治疗组(92.45%)高于对照组(71.05%)。两组复发率差异有显著性(P<0.05),治疗组(7.55%)低于对照组(28.95%)。结论Nd:YAG激光治疗尿道内尖锐湿疣治愈率高、复发率低,优于CO2激光,是治疗尿道内尖锐湿疣安全、有效的方法。     

Q开关Nd:YAG激光治疗错误文眉103例疗效观察

目的:观察Q型YAG激光祛除错误文眉的疗效.方法:选用波长1.064μm,工作电压340～400V,调Q脉冲式Nd:YAG激光机治疗103例错误文眉.结果:痊愈83例,占80.58%;显效18例,占17.48%;有效2例,占1.94%;总有效率98%.结论:应用Q型YAG 1.064μm波长祛除错误文眉,疗效满意,不留疤痕,是目前祛除错误文眉的安全、高效方法.     

Nd:YAG激光治疗臭汗症临床观察

为比较应用Nd:YAG激光治疗臭汗症的疗效,应用3种激光参数治疗臭汗症比较。53例患者分为A、B、C3组,A组:输出功率50W～60W之间,每行距离1.5cm,光纤插入皮下组织深度0.5cm;B组输出功率60W～70W之间,每行距离1cm,光纤插入皮下组织0.6cm;C组输出功率>70W,每行距离0.6cm,光纤插入皮下组织0.7cm～0.8cm。结果:C组疗效>B组>A组。     

Q开关Nd:YAG激光治疗蓝黑文身临床观察

目的观察Q开关Nd:YAG激光治疗蓝黑文身的临床疗效及不良反应。方法应用Q开关Nd:YAG激光治疗60例蓝黑文身患者,波长为1064nm,光斑直径3mm～4mm,能量密度4.5～6.0J/cm2,频率10Hz,脉宽10ns。治疗间隔时间为2～3个月,治疗3～4次。结果 4次治疗后有效率为95%,痊愈率为80%,疗效与治疗次数成正相关。10例(16.7%)患者出现暂时性色素减退,2例(3.3%)患者出现凹陷性瘢痕。色素减退均可在随后的1～3个月内逐渐恢复,凹陷性瘢痕轻者可用皮肤磨削术修复,重者有待于点阵激光治疗。结论 Q开关Nd:YAG激光治疗蓝黑文身效果满意,无明显不良反应及并发症。     

长脉冲可调脉宽1064nmNd：YAG激光治疗小儿皮肤血管瘤196例疗效分析

随着激光技术的发展,激光在血管瘤治疗方面的应用越来越多.过去我们常采用连续Nd:YAG(1064 nm)激光治疗,该激光作用深、疗效快,但极易遗留明显瘢痕.2007年4-10月,我科采用长脉冲可调脉宽1064 nm Nd:YAG激光治疗196例小儿血管瘤,取得了满意的疗效.     

Q开关Nd:YAG激光治疗雀斑样痣疗效观察

目的:评价波光为532 nm的Q开关Nd:YAG激光对单纯性雀斑样痣的疗效。方法:用Q开关Nd:YAG激光(532 mn,光斑直径2-3 mm,频率5 Hz)治疗26例单纯性雀斑样痣患者,治疗前后相对比进行评价,并观察不良反应。结果:26例患者治疗1-3次,治疗间隔为2-3月。基本治愈率为50%,有效率为61.5%。结论:单纯性雀斑样痣患者用Q开关532 nm Nd:YAG激光安全而有效。     

长脉冲1064nm Nd∶YAG激光治疗儿童化脓性肉芽肿的临床疗效观察

目的评价长脉冲1064 nm Nd:YAG激光治疗儿童化脓性肉芽肿的疗效及安全性。方法采用长脉冲1064 nm Nd:YAG激光治疗化脓性肉芽肿99例,治疗前复方利多卡因软膏局部外用麻醉,能量100~140 J/cm2,脉冲频率1.0~2.0 Hz,脉宽100~200 ms;1个月后复查,疗效不佳者再次治疗直到皮损消失。结果长脉冲1064 nm Nd:YAG激光治疗化脓性肉芽肿的1次治愈率为76.7%,总治愈率为100%,出现轻度色素沉着者5例(5%),浅表瘢痕者2例(2%),无1例患者出现凹陷性瘢痕或色素减退,随访3个月无复发。结论长脉冲1064 nm Nd:YAG激光治疗儿童化脓性肉芽肿安全有效。     

长脉冲1064nm Nd:YAG激光治疗婴幼儿皮肤血管瘤215例疗效分析

目的:观察长脉冲1064nm Nd:YAG激光治疗婴幼儿皮肤血管瘤临床疗效,并探讨影响疗效的相关因素.方法:应用长脉冲1 064 nm Nd:YAG激光治疗婴幼儿皮肤血管瘤215例,其中鲜红斑痣19例,草莓状血管瘤179例,混合型血管瘤17例.分析其疗效与病变类型、瘤体大小、病变部位及治疗次数的关系.结果:215例患儿中治愈133例,显效67例,有效8例,无效7例,痊愈率和有效率分别为61.9％和93.1％.疗效与血管瘤的病变类型、瘤体的大小以及治疗次数有关,但与其病变部位无明显相关性.治疗后暂时性色素沉着、暂时性色素减退、浅表性瘢痕、头部毛发减少或消失的发生率分别为48.8％、8.3％、4.6％和3.7％.结论:长脉冲1064nm Nd:YAG激光治疗婴幼儿皮肤血管瘤疗效好,安全性较高,不良反应轻,可在临床上推广使用.     

Q-开关Nd:YAG激光治疗扁平疣72例疗效观察

笔者于1999年11月～2001年12月采用Q-开关Nd:YAG激光治疗扁平疣72例,取得满意效果,现报告如下。1病例与方法病例选择:72例扁平疣患者均为笔者所在医院门诊患者,其中男26例,女46例,年龄8～35岁,病程均>半年,皮疹数目在50枚以上,分布以面部为主。所有患者既往接受过3种以上的治疗,未见好转,皮疹数目不减少或仍在增多。治疗方法:所有患者均采用Q-开关Nd:YAG激光机(MedliteⅣ)治疗,治疗前照相作为评价资料。对于小儿或对痛觉敏感者,治疗前1h于病变部位涂表面麻醉药膏(5%ELMA,Sweden),常规消毒。激光治疗参数设定:波长532nm,光斑2mm,频率5…     

长脉宽1064nmNd:YAG激光治疗婴儿血管瘤疗效评价

目的：评价长脉宽1064nmNd:YAG激光治疗婴儿血管瘤的临床疗效及不良反应。方法：回顾性分析61例经长脉宽1064nmNd:YAG激光治疗的婴儿血管瘤,治疗参数：3mm光斑,脉宽30-40ms,能量密度180-220J/cm2,DCD30/20/30ms,间隔时间为4周,治疗次数1-7次不等,所有患儿均为浅表血管瘤的隆起性皮损。 结果：57例患儿皮损改善76%～100%,4例改善51%～75%。不良反应包括： 水疱20例 （32.79%）,1天～10天修复;浅表瘢痕9例（14.75%）;色素减退5例（8.20%）;色素沉着4例（6.56%）;毛发稀少或缺失3例（4.92%）。随访3个月时色素改变及瘢痕均有不同程度的改善,但毛发改变无明显改善。结论：长脉宽1064nmNd:YAG激光治疗婴儿血管瘤有效,但不良反应率较高。     

Angiolymphoid hyperplasia with eosinophilia: Successful treatment with the Nd:YAG laser

Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon idiopathic proliferation of blood vessels that manifests in adults as isolated or grouped papules, plaques, or nodules in the skin of the head and neck. We describe the case of a 31‐year‐old woman with a 3‐year history of persistent ALHE, located on the tragus of her right ear, with no sign of spontaneous regression over a period of 3–6 months and refractory to intralesional corticosteroids. We report the successful use of the Nd:YAG laser for this condition, which offered excellent symptomatic and cosmetic results and suggests the consideration of this modality in the treatment of ALHE.     

Q‐switched Nd:YAG laser for cosmetic tattoo removal

Laser is a widely accepted tool for tattoo removal, with standardized treatment protocols. Nevertheless, cosmetic tattoo removal may be challenging, because tattoos are performed in proximity of “sensitive” areas and because the ink used in cosmetic tattoos may contain substances that are not standardized and may modify their color at a high temperature. In this case series, we aim to evaluate the effectiveness of Q‐switched (QS) Nd:YAG laser for cosmetic tattoo removal. Our study included 20 patients with cosmetic tattoos of lips, eyebrows, and eyeliners treated with QS Nd:YAG laser. Before treatment, an accurate preoperative assessment was performed, taking into account both patient and tattoo characteristics. Complete tattoo removal was obtained in all the cases and no major complications occurred. Adverse events were mild, mostly represented by erythema. All patients reported a high level of satisfaction. Selective photothermolysis enables complete tattoo removal, even in the case of cosmetic tattoos. However, cosmetic tattoos require a personalized treatment based on an accurate preoperative assessment which takes into account both patient and tattoo characteristics. QS Nd:YAG laser may be considered a good choice in the treatment of cosmetic tattoos, because it enables complete removal with acceptable secondary effects.     

Lichen sclerosus associated with Nd:YAG laser therapy

Laser is the most efficient and popular method in hair removal. The most common side effects of laser assisted hair removal are pain, erythema, edema, hypopigmentation, hyperpigmentation, blistering, crusting, erosions, purpura, folliculitis, and scar formation (1 Nanni CA, Alster TS. Laser-assisted hair removal: side effects of Q-switched Nd: YAG, long-pulsed ruby, and alexandrite lasers. J Am Acad Dermatol. 1999;41(2 Pt 1):165–71. doi:10.1016/S0190-9622(99)70043-5.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). Herein, for the first time we describe a case of lichen sclerosus (LS) following hair removal with long pulsed 1064 nm Nd:YAG laser therapy.     

Retrospective analysis of melasma treatment using a dual mode of low-fluence Q-switched and long-pulse Nd:YAG laser vs. low-fluence Q-switched Nd:YAG laser monotherapy

Background: Despite the effectiveness of low-fluence Q-switched Nd:YAG laser (QSNY) treatment in melasma, adverse events, including mottled hypopigmentation (MH) and rebound hyperpigmentation (RH) have been reported. Objective: To compare the effectiveness and safety of combination therapy using low-fluence QSNY and long-pulse Nd:YAG laser (LPNY) (Dual toning), with low-fluence QSNY monotherapy (QS toning), in Asian melasma patients. Materials and methods: Patients were treated for 10 sessions at 1-week intervals with QSNY (6 mm spot); 2.5–3.0 J/cm² for QS toning (n = 177) or 2.1–2.5 J/cm² for dual toning (n = 183). The dual toning group was immediately treated with LPNY (7 mm spot, 15–17 J/cm²). The results were evaluated using the modified Melasma Area and Severity Index (mMASI) score and the physician's global assessment. Results: MH or RH were significantly lower (1.1% vs. 14.1%) and the treatment efficacy was improved (median decrease of mMASI, 3.6 vs. 3.0) in the dual toning group compared with the QS toning group. Periorbital melasma showed distinctively high rates of adverse events in the QS toning group (23.9% vs. 5.7%), which were significantly reduced in the dual toning group (2.9%). Conclusion: Dual toning could represent a safe and effective treatment for Asian melasma patients, as it is associated with minimal adverse events and improved treatment efficacy compared with QS toning monotherapy.     

调Q开关倍频Nd：YAG激光和超脉冲CO2激光对早期脂溢性角化病的疗效比较

目的探讨两种治疗方法对于早期脂溢性角化病的临床效果。方法将患者随机分为两组,分别用调Q开关Nd：YAG激光和超脉冲CO2激光治疗,对比观察治疗效果：结果调Q开关Nd：YAG激光总有效率为96．12％,超咏冲CO2激光治疗组总有效率97．24％,没有统计学差异。术后两组色素沉着率分别为8．74％和25．35％;色素减退率分别为4．37％和7．38％;调Q开关Nd：YAG激光没有疤痕形成,超脉冲CO2激光疤痕形成率为4．15％;均有统计学差异。结论表明调Q开关Nd：YAG激光是一种理想的治疗手段。     

Nd:YAG laser for effective treatment of multiple cylindroma of the scalp

The case presented illustrates the successful effect of the Nd:YAG laser in the treatment of multiple giant scalp tumours in a patient who would not accept surgical excisions. A 60‐year‐old woman with multiple cylindroma covering the whole scalp area was treated with a Nd:YAG laser in a cutting continuous mode. Postoperative healing by second intention within 3–4 weeks left limited superficial scars. No tendency to relapse was noted during a follow‐up of 4 years.