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同时记录了30名健康老年人(60~83岁)的听觉脑干诱发电位(BAEP)和短潜时体感诱发电位(SSEP)发现:BAEP的Ⅰ波峰潜时,Ⅰ~Ⅲ,Ⅲ~Ⅴ峰间传导时间及SSEP的NCV、N_(20)-N_9-W、W值,在部分健康老年人可出现明显延长。Ⅰ~Ⅲ、Ⅲ~Ⅴ峰间传导时间、N_(20)-N_9-W值与W值的延长无同步关系。显示了中枢神经系统老化与实际年龄的不一致性和中枢神经系统各部老化程度的不一致性。 相似文献
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陈星 《吉林大学学报(医学版)》1999,25(4):545-546
脑性瘫痪(脑瘫)是小儿神经系统常见的一种疾病.我国发病率为1.8‰~6‰[1].早期发现、及时治疗,对提高康复率有重要意义.本文作者对1995~1997年临床确诊为"脑瘫"的52例患者进行了脑干听觉诱发电位(BAEP),躯体感觉诱发电位(SEP)两项检查的对比研究,现报道如下. 相似文献
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腔隙性脑梗死(lacunar infarction,LI)是老年人常见多发疾病,随着年龄的增高,发病率不断上升。脑干听觉诱发电位(brainstem auditory evoked potential,SAEP)和短潜伏期体感诱发电位(short lmeney somatosensory evoked potential,SSEP)常用于神经外科手术监测神经功能状态的评估中。尽管近年来有将BAEP、SSEP应用于脑血管病的脑干及外周神经功能状态的评测,但对于老年人群LI的脑干功能状态的评测鲜为报道。 相似文献
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利用有效方式,全面缩短昏迷患者清醒时间意义重大。脑干听觉诱发电位一般被用于评价患者的脑干功能,其在患者脑干出现轻度损伤时即可发生改变。而体感诱发电位则可以体现出患者大脑半球功能、丘脑功能改变情况,经感觉系统实施系列性生理传导,能够积极展现患者受损神经功能情况。对于昏迷患者实施脑干听觉诱发电位联合体感诱发电位检测,不仅能够积极评估患者疾病预后,还有助于指导实施针对性治疗。 相似文献
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目的 研究急性重型脑血管病的脑干听觉诱发电位(BAEP)和短潜伏期体感诱发电位(SSEP) 方法 选择30例急性重型脑血管病患者及60名正常对照组,应用丹麦仪器完成BAEP和SSEP检查,分别在发病后10h.2、5、7、10及30d观察脑干功能,并与临床表现和影像学检查相比较。结果 发病后10h,2、5、7、10及30d时,BAEP和SSEP发现的脑干损害均明显早于临床表现和影像学检查;结论 BAEP和SSEP在检测重型脑血管病病人脑干功能方面具有定量评价作用并与临床表现和影像学检查相比,BAEP和SSEP能更好地反映重型脑血管病病人的脑干功能情况。 相似文献
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多种诱发电位评估急性昏迷病人的预后 总被引:7,自引:0,他引:7
目的 研究诱发电位对急性期昏迷病人预后的价值。方法 180例患者在昏迷后第1、3、7、10天进行脑干反射检查、GCS评分和多种诱发电位检测。结果 在昏迷第1天GCS和脑干反射无预测价值,在第1、3、7、10天GCS和脑干反射的预后准确率均低于90%,各种诱发电位的预后准确率均高于93%。结论 体感和听觉诱发电位结合对昏迷患者预后的准确率高于GCS和脑干反射。 相似文献
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目的 :探索颅内压 (ICP)升高过程中体感诱发电位 (SEPs)与脑干听觉诱发电位 (BAEPs)的变化规律。方法 :采用幕上不同部位放置球囊引起急性ICP增高的动物模型。将新西兰兔 30只分为 3组 :A组动物球囊置入右顶部硬膜下 ;B组动物球囊置入右颞底 ,C组以上部位动物各半 ,球囊内不注水。结果 :(1)A组SEPsP1波幅在ICP升至(1.48± 0 .35 )kPa即发生显著变化 ,而B组中ICP达 (8.10± 1.2 5 )kPa才出现波幅显著压缩。A组BAEPs在ICP升至(9.40± 1.6 0 )kPa时才出现IV ,V ,VII波的PL延长 ,而B组在ICP为 (3.11± 0 .80 )kPa时即见III波PL显著延长。 (2 )随ICP增高 ,P1波幅先随之升高 ,继而转为下降。结论 :SEPs与BAEPs的变化不仅受ICP高低的影响 ,还与病变的部位有关 ;SEPsP1波幅在ICP增高过程中呈先升后降的趋势 相似文献
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目的:研究帕金森病(PD)患者是否存在脑干听觉传导通路与视觉传导通路的损害.方法:应用意大利产Reporter型-4通道诱发电位仪对PD患者(男20例,女12例)、非帕金森病患者(对照组,男19例,女11例)进行脑干听觉诱发电位(BAEP:Ⅰ、Ⅲ、Ⅴ峰潜伏期(PL)及Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ-Ⅴ峰间潜伏期(IPL))、视觉诱发电位(VEP:P100 PL)检测.结果:PD患者BAEP异常率为50%,其中Ⅲ PL异常率为22%,Ⅴ PL异常率为19%;Ⅲ PL为(3.87±0.30)ms,Ⅴ PL为(5.79±0.30)ms.Ⅲ-Ⅴ>Ⅰ-Ⅲ为31%;与对照组比较(Ⅲ PL(3.56±0.22)ms,Ⅴ PL(5.48±0.26)ms)差异有统计学意义(t=5.83,5.85;P<0.01).PD患者P100 PL为(105.17±12.42)ms,对照组为(98.62±9.46)ms,2者相比差异有统计学意义(t=2.49,P<0.05).结论:帕金森病患者除存在黑质-纹状体病变外,可能还存在脑干听觉传导通路与视觉传导通路的损害;听觉诱发电位与视觉诱发电位可作为临床评价帕金森病的客观指标. 相似文献
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68例椎基底动脉供血不足瞬目反射和脑干听觉诱发电位与经颅多普勒的相关性 总被引:4,自引:0,他引:4
目的 探讨椎基动脉供血不足(VBI)脑干功能与经颅多普勒(TCD)的相关性。方法 对68例临床诊断VBI的患者及30例非VBI患者进行BR、BAEP和TCD检测。结果 VBI组脑干功能损害84.6%,TCD异常率为83.1%,χ^2检验差异不显著;非VBI组脑干功能损害8.3%,TCD异率为46.6%,χ^2检验差异显著。VBI组脑干功能损害及TCD异常者为98/136,皆正常者为24/136,两 相似文献
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目的用最大长度序列(MLS)脑干听觉诱发电位技术检测有围产期缺氧早产儿生后早期的脑干功能,研究不同程度缺氧对脑干功能的影响,并比较MLS脑干听觉诱发电位是否较常规法对异常的检出具有优越性。方法胎龄29~33+6周的早产儿,重度缺氧组51例,轻度缺氧组36例,对照组为相对正常早产儿41例。MLS脑干诱发电位的声刺激速率为91、227和455次/秒,选常规法21次/秒作为对照,观察指标为Ⅰ、Ⅲ、Ⅴ波潜伏期和振幅,Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ-Ⅴ峰间期。结果随着缺氧程度加重,缺氧组早产儿V波潜伏期、Ⅲ-Ⅴ和Ⅰ-Ⅴ峰间期较正常对照组逐渐延长,V波振幅逐渐降低;通过MLS提高刺激速率后,缺氧早产儿Ⅲ波的潜伏期、Ⅰ-Ⅲ峰间期也表现出明显延长,Ⅲ波振幅也逐渐降低,并且随刺激速率逐渐增高,统计学差异逐渐明显。轻度缺氧组常规21次/秒时各参数与正常早产儿组无明显差异,但在MLS227及455次/秒时,Ⅲ、Ⅴ波潜伏期,各个峰间期也显示出延长[455次/秒时,轻度缺氧组Ⅲ波潜伏期为(6.55±0.53)ms,Ⅴ波潜伏期为(10.13±0.86)ms,Ⅰ-Ⅲ峰间期为(3.60±0.34)ms,Ⅲ-Ⅴ峰间期为(3.58±0.57)ms,Ⅰ-Ⅴ峰间期为(7.18±0.73)ms],同时部分振幅降低;重度缺氧组与轻度缺氧组的差异主要为Ⅴ波潜伏期、Ⅲ-Ⅴ和Ⅰ-Ⅴ峰间期延长及Ⅴ波振幅降低,而与正常早产儿组比较不仅上述差异更加显著,同时Ⅲ波的潜伏期及振幅、Ⅰ-Ⅲ峰间期也都显示出异常[455次/秒时,重度缺氧组Ⅴ波潜伏期为(10.57±0.93)ms,Ⅲ-Ⅴ峰间期为(3.93±0.53)ms,Ⅰ-Ⅴ峰间期为(7.60±0.73)ms,Ⅴ波振幅为(0.02±0.02)μV]。结论围产期缺氧会对早产儿生后早期的脑干功能造成损伤,且随缺氧程度加重诱发电位的变化也更加明显。MLS脑干听觉诱发电位通过提高刺激速率,加大神经元负荷,对脑损伤有更高的诊断价值。 相似文献
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Combined monitoring of evoked potentials during microsurgery for lesions adjacent to the brainstem and intracranial aneurysms 总被引:9,自引:0,他引:9
Background Neurophysiologic monitoring during surgery is to prevent permanent neurological injury resulting from surgical manipulation. To improve the accuracy and sensitivity of intraoperative neuromonitoring, combined monitoring of transcranial electrical stimulation motor evoked potentials (TES-MEPs), somatosensory evoked potentials (SSEPs) and brainstem auditory evoked potentials (BAEPs) was attempted in microsurgery for lesions adjacent to the brainstem and intracranial aneurysms.Methods Monitoring of combined TES-MEPs with SSEPs was attempted in 68 consecutive patients with lesions adjacent to the brainstem as well as intracranial aneurysms. Among them, 31 patients (31 operations, 28 of posterior cranial fossa tumors, 3 of posterior circulation aneurysms) were also subjected to monitoring of BAEPs. The correlation of monitoring results and clinical outcome was studied prospectively.Results Combined monitoring of evoked potentials (EPs) was done in 64 (94.1%) of the 68 patients. MEPs monitoring was impossible for 4 patients (5.9%). No complication was observed during the combined monitoring in all the patients. In 45 (66.2%) of the 68 patients, EPs were stable, and they were neurologically intact. Motor dysfunction was detected by MEPs in 8 patients, SSEPs in 5, and BAEPs in 4, respectively. Conclusions A close relationship exists between postoperative motor function and the results of TES-MEPs monitoring. TES-MEPs are superior to SSEPs and BAEPs in detecting motor dysfunction, but combined EPs serve as a safe, effective and invasive method for intraoperative monitoring of the function of the motor nervous system. Monitoring of combined EPs during microsurgery for lesions adjacent to the brainstem and intracranial aneurysms may detect potentially hazardous maneuvers and improve the safety of subsequent procedures. 相似文献
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对120例健康人进行体感诱发电位(SEP)检测。按不同性别、年龄分为成年组(30~59岁)及老年组(60~79岁)。结果表明,SEP各波潜伏期(PL)及波峰问期(1PL)的平均值左、右侧比较无统计学差异,但男、女组间,成年组与老年组间却有明显差异。Erb点电位(N_9)及颈髓电位(N_(13))的PL与臂长、身高呈正相关,有非常显著性意义。因此,临床判断病人的SEP值时,应考虑性别、年龄、臂长。身高等因素的影响,并注意选取正常值范围的界限,才能提高其诊断准确率。 相似文献
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Objective To determine whether lead affects brainstem auditory evoked potentials (BAEPs) in low-to-moderate lead exposed children. Methods BAEPs were recorded from 114 asymptomatic children aged 1-6 years. Average values were calculated for peak latency (PL) and amplitude (Amp). Whole blood lead (PbB) levels were assessed by graphite furnace atomic absorption spectroscopy. Based on their PbB levels, subjects were divided into low lead (PbB<100 μg/L) and high lead subgroups (PbB ≥100 μg/L). Results The PbB levels of the 114 subjects ranged from 32.0 to 380.0 μg/L in a positively skewed distribution. The median of PbB levels was 90.0 μg/L while the arithmetic average was 88.0 μg/L. Of the subjects, 43.0% (49/114) had levels equal to or greater than 100 μg/L. Bilateral PLs Ⅰ, Ⅴ, and Ⅲ of the left ear in the high lead subgroup were significantly longer than those in the low lead subgroup (P<0.05). A positive correlation was found between PbB levels and bilateral PLs Ⅰ, Ⅴ and Ⅲ of the left ear (P<0.05), after controlling for age and gender as confounding factors. A significant and positive correlation between PbB levels and PL Ⅰ of the left ear, even when PbB levels were lower than 100 μg/L, in the low subgroup (r=0.295, P=0.019) was also found.Conclusions Lead poisoning in children younger than 6 years old is a very serious problem to which close attention should be paid. The indications that lead prolongs partial PLs may imply that lead, even at PbB levels lower than 100 μg/L, impairs both the peripheral and the central portions of the auditory system. BAEPs may be a sensitive detector of subclinical lead exposure effects on the nervous system in children. 相似文献