Changes in osseous correction after proximal tibial osteotomy: radiostereometry of closed- and open-wedge osteotomy in 33 patients

33 patients (22 men), median age 54 (40-68) years, with medial gonarthrosis grades 1-3, were treated by closed-wedge osteotomy (high tibial osteotomy = HTO, n 16) or open-wedge osteotomy by hemicallotasis (hemicallotasis osteotomy = HCO, n 19). 2 patients were operated on bilaterally. The patients were studied by RSA (radiostereometric analysis) for measuring 3-D changes in the correction achieved. In the HTO group the RSA measurements were obtained at the time of plaster removal, 1 month later and 1 year after surgery. In the HCO group, the RSA measurements were performed at the time of removal of the external fixator, 1 month later and 1 year after surgery. After removal of the fixation, HTO was associated with increased medial/lateral and distal translation of the proximal segment, compared to HCO. In addition, the tibial plateau rotated more around the longitudinal axis of the tibia after HTO.     

Open-wedge osteotomy by hemicallotasis or the closed-wedge technique for osteoarthritis of the knee. A randomised study of 50 operations

We describe the results of 50 operations carried out on 46 patients with medial osteoarthritis of the knee of Ahlb?ck grade 1 to 3. Patients were randomised either to a closed-wedge high tibial osteotomy (HTO) or an open-wedge procedure based on the hemicallotasis technique (HCO). Their median age was 55 years (38 to 68). The preoperative median hip-knee-ankle (HKA) angle was 171 degrees (164 to 176) in the HTO group and 173 degrees (165 to 179) in the HCO group. After six weeks, the median HKA angle was 185 degrees (176 to 194) in the HTO group and 184 degrees (181 to 188) in the HCO group. In the HTO group, seven patients were within the range of 182 degrees to 186 degrees compared with 21 in the HCO group (p < 0.001). One year later, ten HTO patients were within this range while the HKA angulation in the HCO group was unchanged. At two years the numbers were 11 and 18, respectively. We evaluated the clinical results on the Hospital for Special Surgery, Lysholm and Wallgren-Tegner activity scores, and patients completed part of the Nottingham Health Profile questionnaire. An impartial observer at the two-year follow-up concluded that all scores had improved, but found no clinical differences between the groups.     

Fixation stability following high tibial osteotomy: a radiostereometric analysis

Fifteen patients with varus gonarthrosis underwent high tibial osteotomy and internal fixation with an L-shaped rigid plate. In 9 patients, an average wedge size of 7.1 degrees was resected leaving the medial cortex of the proximal tibia intact (group 1). In 6 patients, the medial cortex of the proximal tibia was unintentionally fractured during surgery when an average 10.7 degrees wedge was resected (group 2). Postoperatively, patients were monitored with serial radiostereometric analysis (RSA), conventional radiographs, and clinical evaluation for 1 year. In group 2, RSA revealed a 1.3-mm increase in lateral displacement of the distal tibial segment within 3 weeks following surgery. Twelve weeks after surgery, micromotion between tibial segments was below the precision of the RSA setup in 14 of 15 patients. These findings indicate that in cases with larger wedge sizes (>8 degrees), fracture of the medial cortex of the proximal tibia was frequent and resulted in significant lateral displacement of the distal tibia relative to the tibial plateau. In such cases, prophylactic additional medial fixation rather than lateral L-plate fixation alone is advised to minimize the propensity for lateral displacement of the distal tibia and to avoid subsequent loss of correction.     

关节镜联合开放楔形胫骨高位截骨术治疗膝关节骨关节炎的早期效果

目的 分析关节镜结合胫骨高位截骨术((high tibial osteotomy, HTO)治疗膝关节骨关节炎的早期效果。方法　选取2018年6月至2019年6月绵阳市中心医院骨科收治的因膝关节骨关节炎接受关节镜联合胫骨高位截骨术的患者88例(88膝)患者。收集评价患者美国特种外科医院膝关节评分(hospital for special surgery knee score, HSS)、视觉模拟评分(visual analogue scale,VAS)、手术前后下肢全长下X线片胫股角(femorotibial angle, FTA)、胫骨近端内侧角(medial proximal tibial angle, MPTA)等指标,并进行分析。结果　全部患者均得到随访,随访时间6~18月,平均12月。患者HSS评分术前(57.46±4.87)分、术后(79.19±2.48)分、术后1月(81.52±3.97)分逐渐增加,VAS评分术前(4.03±0.82)分、术后(2.52±0.50)分、术后1月(1.00±0.81)分逐渐降低,差异有统计学意义(P＜0.05)。FTA术前(179.72±2.30)°纠正至术后(172.81±1.36)°, MPTA术前(83.35±1.61)°纠正至术后(88.47±7.16)°,差异有统计学意义(P＜0.05)。结论　关节镜联合胫骨高位截骨术治疗膝关节骨关节炎早期在下肢力线及疼痛改善方面能取得较为满意效果。但其膝关节软骨恢复情况等需要进一步长期随访研究。     

关节镜并胫骨高位截骨术治疗伴内翻畸形膝关节单间室骨关节炎

[目的]探讨膝关节镜并内侧开放式胫骨高位截骨术治疗膝关节单间室骨性关节炎的临床疗效.[方法]自2004年4月～2009年12月在本院行膝关节镜并内侧开放式胫骨高位截骨术患者46例(64膝),平均随访32.4个月,分别测量患者膝关节术前及术后的股胫角,并对患者膝关节进行HSS评分.[结果]所有患者术后股胫角术前平均内翻-4.44°±1.18°矫正到术后平均外翻8/37°±1.10°(P<0.001).HSS评分由术前的(54.25±5.40)分提高到术后的平均(89.67±3.38)分(P<0.001).[结论]膝关节镜并内侧开放式胫骨高位截骨术足治疗轻中度膝关节单问室骨性关节炎的有效手术方法,近中期疗效满意.     

Patellar height and the inclination of the tibial plateau after high tibial osteotomy. The open versus the closed-wedge technique

Our aim was to compare the degree of patellar descent and alteration in angle of the inclination of the tibial plateau in lateral closing-wedge and medial opening-wedge high tibial osteotomy (HTO) in 51 consecutive patients with osteoarthritis of the medial compartment and varus malalignment. Patellar height was measured by the Insall-Salvati (IS) and the Blackburne-Peel (BP) ratios. The tibial inclination was determined by the Moore-Harvey (MH) method. Multivariate linear regression analysis was used to determine the influence of the type of HTO (closing vs opening wedge) on the post-operative patellar height or tibial inclination. The intra- and interobserver variability of these methods was determined before operation and at follow-up at one year. After an opening-wedge HTO the patellar height was significantly more decreased (mean post-operative difference: IS = 0.15; 95% confidence interval (CI) 0.06 to 0.23; BP = 0.11; 95% CI 0.05 to 0.18) compared with a closing-wedge HTO. The angle of tibial inclination differed significantly (mean post-operative difference MH = -6.40 degrees; 95% CI -8.74 to -4.02) between the two HTO techniques, increasing after opening-wedge HTO and decreasing after closing-wedge HTO. There was no clinically-relevant difference in the intra- and interobserver variability of measurements of patellar height either before or after HTO.     

胫骨高位截骨术与腓骨截骨术治疗膝骨关节炎临床疗效比较

目的比较胫骨高位截骨术(HTO)与腓骨截骨术治疗膝关节骨性关节炎(KOA)临床疗效。 方法回顾性分析于2015年1月至2016年12月在佛山市中医院骨九科行HTO或腓骨截骨术治疗KOA的患者。HTO组共37例,男11例,女26例,平均年龄(59±3)岁;腓骨截骨组共26例,男9例,女17例,平均年龄(59±3)岁。分析比较两组的手术耗时、术中失血量、住院总花费、术后并发症、随访期内再次行膝关节置换情况。采用膝关节Lysholm评分、西安大略和曼彻斯特大学关节炎指数(WOMAC)对术前、术后6个月、术后12个月随访时膝关节功能进行评估。数据采用SPSS13.0统计学软件进行统计学分析。手术耗时、术中失血量、住院总花费、Lysholm评分、WOMAC评分均采用独立样本t检验,术后并发症、随访期内再次行膝关节置换情况比较采用卡方检验。 结果HTO组术后随访中位数15.7个月,腓骨截骨组术后随访中位数14.9个月。HTO组手术耗时(t＝21.094,P<0.05)、术中失血量(t＝9.91,P<0.05)、住院总花费(t＝65.471,P<0.05)均显著劣于腓骨截骨组。HTO组有1例(2.7%)并发症,腓骨截骨组有2例并发症(7.7%),采用Fisher确切概率法分析,差异无统计学意义(P＝0.785)。两组患者术前膝关节Lysholm评分、WOMAC评分差异均无统计学意义。术后6个月Lysholm评分HTO组显著优于腓骨截骨组(t＝2.426,P<0.05)。WOMAC评分HTO组显著劣于腓骨截骨组(t＝3.997,P<0.01)。术后12个月HTO组Lysholm评分(t＝2.979,P<0.01)、WOMAC评分(t＝－2.472,P<0.05)均显著优于腓骨截骨组。 结论行胫骨高位截骨术治疗膝关节骨性关节炎比行腓骨截骨术手术耗时长、术中出血多、住院总花费多;术后12个月的随访提示行胫骨高位截骨术能比行腓骨截骨术取得更好的膝关节功能。     

Open-wedge osteotomy of the proximal tibia hemicallotasis.

Conventional high tibial osteotomy for losteoarthritis of the medial compartment of the knee with closed-wedge or dome osteotomy (DMO) may produce shortening of the patellar tendon and loss of inclination of the proximal tibial plateau or of the offset of the tibial condyle relative to its bony axis. This can make subsequent total knee arthroplasty technically demanding. We undertook a prospective study comparing these changes after DMO with those after using open-wedge osteotomy hemicallotasis (HCO). A total of 50 knees with arthritis of the medial compartment in 46 consecutive patients was randomly allocated to either DMO or HCO. There were no significant differences between the groups with regard to age, gender, femorotibial angle before operation or the angle of correction. Radiological studies showed that HCO caused little change in the length of the patellar tendon or the inclination angle of the tibial plateau, while after DMO both gradually decreased. The degree of tibial condylar offset increased in both groups, but less so in the HCO group.     

Total knee arthroplasty after high tibial osteotomy: a comparison of opening and closing wedge osteotomy

Purpose

High tibial osteotomy (HTO) is frequently used to treat varus osteoarthritis in younger patients with the goal of delaying the need for total knee arthroplasty (TKA). While it has been reported that the results of TKA following HTO are worse than those in patients without prior knee surgery, the influence of osteotomy technique (medial opening-wedge versus lateral closing-wedge) has not been explored. The purpose of this study was to evaluate the influence of HTO technique on the performance and results of TKA.

Methods

A total of 141 TKA’s performed in 118 patients with prior HTO (24 opening wedge and 117 closing wedge) were reviewed at a mean follow-up of two years. Reviewed data included intra-operative factors (tourniquet time, the need for additional exposure, and intra-operative complications), clinical results (International Knee Score (IKS)) and radiographic assessment of limb alignment.

Results

The average IKS knee and function scores improved from 54.0 and 60.3 to 87.0 and 79.5 (p <  0.0001). There was no significant difference in IKS scores based on osteotomy technique. There was a trend toward an increased need for tibial tubercle osteotomy in the closing wedge group. There was an increased need for extensive medial release in the opening wedge group and extensive lateral release in the closing wedge group. No differences in tourniquet time, complication rates, or hip-knee-ankle angle were noted between the two groups.

Conclusions

Radiographic limb alignment, patient-reported outcomes, and complication rates are equal in patients undergoing TKA after opening and closing wedge HTO.     

Combined medial open-wedge high tibial osteotomy and modified Maquet procedure for medial compartmental osteoarthritis and patellofemoral arthritis of the knee

Purpose

Patellofemoral arthritis comes frequently with medial compartmental osteoarthritis. The combination of closed wedge high tibial osteotomy with tibial tuberosity anteriorization osteotomy has been introduced in several reports, but this technique is a technically demanding procedure and the outcomes of this technique show variable results. This article describes a novel osteotomy technique that combines medial open-wedge high tibial osteotomy (HTO) and tibial tuberosity anteriorization osteotomy (TTAO) for medial compartmental osteoarthritis and patellofemoral arthritis of the knee.

Methods

Twelve knees in 10 patients who were diagnosed with combined medial compartmental osteoarthritis with patellofemoral compartmental arthritis were treated with the combination of medial open-wedge HTO and TTAO and were followed up for more than 1 year. We evaluated the patients with the Lysholm functional questionnaires, the hospital for special surgery score (HSS), and the international knee documentation committee (IKDC) criteria (mean follow-up, 14.8 months).

Results

Union was achieved in all cases within 12 weeks. The mean Lysholm score increased from 42 preoperatively to 82.5 postoperatively (p < 0.001), the HSS increased from 57.5 preoperatively to 83 postoperatively (p < 0.001), and the IKDC score increased from 51 preoperatively to 82 postoperatively (p < 0.001). There were no other complications, such as iatrogenic fractures, nonunion, wound problem, collapse or loss of correction, and so on.

Conclusions

The combination of medial open-wedge HTO and modified Maquet procedure (TTAO) is considered to be an effective treatment modality for medial and patellofemoral compartmental osteoarthritis. This technique could, therefore, constantly provide a minimally invasive, precise correction of the deformity and a firm fixation that is enough to allow early rehabilitation.     

Progression of joint arthrosis 10 to 15 years after high tibial osteotomy

Forty-eight knees in 44 patients who had a high tibial osteotomy performed for medial compartment osteoarthritis were reevaluated twice, once at 1 year after surgery and again at 10 to 15 years after the high tibial osteotomy, to determine the effects of high tibial osteotomy on progression of medial and lateral joint arthrosis. Radiologically, although arthrosis significantly increased in the medial and the lateral joint compartment, there was no significant difference in the degree of progression between the two compartments. There was a significant correlation between the progression of medial joint arthrosis evaluated at 10 years or more after surgery and the femorotibial angle measured at 1 year. There was no significant correlation between the progression of lateral joint arthrosis in 10 to 15 years and the femorotibial angle measured at 1 year. The average knee function score improved significantly from 59.1 +/- 5.5 points before surgery to 85.1 +/- 6.1 points at the 1-year followup. At the final followup, the clinical score (80.7 +/- 5.4) had deteriorated relative to the 1-year results but still was significantly better than the preoperative score. The current results indicate that the greater the surgical valgus correction, the slower the progression of medial joint arthrosis. Lateral joint arthrosis did not progress more quickly after high tibial osteotomy, even if an overcorrection was performed.     

Knee joint arthroplasty after tibial osteotomy

A total of 29 consecutive knee joint arthroplasties in 24 patients who underwent previous high tibial osteotomy (HTO) for medial unicompartment osteoarthritis of the knee and followed up for a mean of 97 months were compared with a control group of 28 patients with 29 primary total knee arthroplasty (TKA) without previous HTO. Results for the osteotomy group were satisfactory in 96.5% of cases. In one patient loosening of the implant occurred after 37 months, which required prosthesis revision. Three patients underwent a further operation of secondary patella resurfacing for patella pain. The group without osteotomy reported a similar percentage of satisfactory results.     

计算机导航胫骨高位截骨联合关节镜的短期疗效

目的观察计算机导航辅助下胫骨高位截骨(HTO)联合关节镜治疗胫骨内翻畸形的临床疗效。 方法本回顾性研究收集了2018年11月至2019年1月在上海长海医院接受治疗的20例膝内翻畸形合并内侧间室骨关节炎的患者,男性7例,女性13例。纳入标准：膝关节内侧间室骨关节炎,症状局限于膝内侧;膝关节内翻畸形,且胫骨近端内翻畸形。排除标准：膝关节外侧间室骨关节炎;外侧半月板损伤或有手术史;膝关节屈曲挛缩>10°;严重肥胖。手术方式为计算机导航辅助下开放楔形胫骨高位截骨联合关节镜手术。测量术前、目标及术后的机械胫股角(mTFA)、胫骨近端内侧角(MPTA)、关节线会聚角(JLCA),测量术前及术后的Lysholm评分及美国特种外科医院(HSS)膝关节评分,进行配对t检验及Mann-Whitney U检验。 结果本组20例患者,平均年龄(55±7)岁,平均随访(11±3)个月。术后mTFA、MPTA、JLCA及力线位置均较术前显著改善。术后Lysholm评分与HSS评分均高于术前[67(60,75) vs. 51(46,61)(Z＝-4.22,P<0.001),67(59,71)vs. 55(49,59)(Z＝-3.64,P<0.001)];术后mTFA、力线位置、矫正角度及撑开高度与术前规划目标无差异统计学意义(P>0.05)。关节镜探查发现6例患者伴有内侧半月板撕裂(其中2例患者为内侧半月板后脚根部撕裂),5例存在内侧肥厚或纤维化的滑膜皱襞,4例股骨内侧髁明显骨赘增生,均予以相应处理。 结论计算机导航辅助下胫骨高位截骨能获得与术前力线矫正计划一致的精确性;关节镜探查时处理关节内半月板、滑膜及骨赘增生等病理性改变,改善内侧间室的局部环境,是提高胫骨高位截骨术疗效必要的操作。     

Unexplained proximal tibiofibular joint pain after high tibial osteotomy

Problems of the proximal tibiofibular joint (pTFj) after high tibial osteotomy (HTO) are rare. With this case report, we strive to highlight the importance of investigating the pTFj in patients with unexplained knee pain after HTO. A 44 year old male patient presented with diffuse pain on his left knee 3 years after medial opening wedge HTO due to medial compartment overloading in a varus knee. Patient described persistent anterior tibial and lateral knee pain. 2 years after HTO, patient underwent implant removal but the knee pain persisted. As the reason for the persistent pain was not identified, further radiological evaluation was done. Single photon emission computerized tomography/computerized tomography (SPECT/CT) revealed that there was no increased uptake within the tibiofemoral joint, indicating a biologically well performed correction of the varus deformity. However, markedly increased tracer uptake was found at the pTFj. On the inherent axial CT scans, it was seen that the proximal screws were too long and placed within the pTFj. Along with this a severe osteoarthritis of the pTFj was identified. The cause of the patient''s pain was then confirmed by a CT guided infiltration of local anesthetic. An arthrodesis of the pTFj was performed and at 12 months followup after the arthrodesis the patient was pain free. This case highlights how important it is to evaluate the pTFj in patients with unexplained pain after HTO. SPECT/CT was helpful in identifying the patient''s problem in this challenging case.     

High tibial osteotomy

High tibial osteotomy (HTO) is a widely performed procedure to treat medial knee arthrosis. In general, published studies on HTO report good long-term results with a correct patient selection and a precise surgical technique. The ideal candidate for an HTO is a middle aged patient (60 to 65 years of age), with isolated medial osteoarthritis, with good range of motion and without ligamentous instability. Some issues that need resolution remain; these include the choice between opening and closing wedge tibial osteotomy, the graft selection in opening wedge osteotomies, the type of fixation, the comparison with unicompartmental knee arthroplasty and whether HTO significantly affects a subsequent total joint replacement. Precise indication, preoperative planning, and operative technique selection are essential to achieve good results.     

A ten- to 15-year follow-up observation of high tibial osteotomy in medial compartment osteoarthrosis.

High tibial osteotomy (HTO) was performed on 86 medially osteoarthritic knees in 78 patients. Twelve patients died during the follow-up period. Fifty-six knees of 51 patients were evaluated twice postoperatively: once at six years after surgery and again after ten to 15 years. Results were satisfactory in 88% of the knees at the six-year follow-up evaluation and in 63% at the post-ten-year follow-up evaluation. Ten-year follow-up results significantly deteriorated. The femorotibial angle (FTA) at the time of bone union after HTO was a significant factor that contributed to the ten-year results. In patients maintaining excellent improvement of knee function at the post-ten-year follow-up evaluation, the mean FTA at one year after surgery was 165 degrees; this value was constant through ten years after HTO. An FTA of 164 degrees-168 degrees should be attained to ensure favorable long-term results in HTO.     

All-polyethylene vs. metal-backed tibial component in total knee arthroplasty-a randomized RSA study comparing early fixation of horizontally and completely cemented tibial components: part 2. Completely cemented components: MB not superior to AP components

Background Uncertainty exists as to whether metal backing (MB) of the tibial component is better than an all-polyethylene component (AP). This is valid for both horizontally and completely cemented components. We evaluated completely cemented MB vs. AP (Part 2).

Patients and methods In a randomized study, 39 patients (40 knees) with knee arthrosis were operated with cemented low-conforming total knee arthroplasty (AGC, Biomet) with a tibial component of uniform thickness (8 mm), cemented both beneath the tibial tray and around the stem. 20 patients had an all-polyethylene (AP) tibial component and 20 patients had an identical but metal-backed (MB) tibial component. We used clinical examination and radiostereometric analysis (RSA) to evaluate the hypothesis that MB improves component fixation. Fixation was evaluated using RSA up to 2 years after surgery. Clinical assessment was performed preoperatively and after 2 years using the Hospital for Special Surgeons (HSS) score.

Results We found no differences in micromotion, and no differences in clinical scores could be detected between the groups at any time point.

Interpretation Our findings indicate that there was equal initial fixation of the AP and MB stemmed monobloc components when they were cemented beneath the tibial plateau and around the stem.

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改良内侧撑开楔形胫骨高位截骨矫正老年膝内翻的临床研究

目的探索高龄(>60岁)膝关节内侧骨关节炎并膝内翻畸形患者的手术技术及疗效。方法 2010年3月至2012年3月,采用改良内侧撑开楔形胫骨高位截骨矫正老年膝内翻畸形46例(52膝)。术前、后均拍患肢全长站立位X线片,测量髋(髋关节中心)-膝(膝关节中心)-踝(踝关节中心)形成的机械轴角度(HKA角),拍侧位X线片,测量胫骨平台后倾角,应用膝关节外科KOOS问卷评分标准对治疗后疗效评估。结果术后有32例(34膝)获随访,其余14例(18膝)因手术后不足3个月被排除在本组样本之外。32例随访时间为3～20个月,平均12.6个月。HKA角从术前(167.6°±3.7°)增加至术后平均(184.5°±1.2°)(P<0.05),胫骨平台后倾角术前平均(12.8°±1.3°),术后纠正到平均(9°±0.9°)(P<0.05);术后第2天带引流管直腿抬高、主动屈、伸膝关节锻炼;第3天,扶走步器负重行走;术后第7天生活已基本恢复自理;术后8～12周截骨端临床愈合。所有患者无一例感染、迟缓愈合、患肢无缺血及感觉障碍等并发症。疗效评估根据手术前、后的膝关节外科KOOS问卷评分结果,术前KOOS评分为(44.1±10.8)分,术后KOOS评分提高到(62.31±11.2)分,通过SPSS20统计学配对样本t检验确定其结果(P<0.05)有统计学差异。结论改良内侧撑开楔形胫骨高位截骨矫正老年膝内翻,是一种适合60岁以上患者的有效方法之一。不仅手术方法简便、组织损伤小、出血少、不易发生并发症,而且术后恢复快、住院时间短、不需要特殊昂贵的耗材,容易被广大患者接受,具有良好的社会效益和经济效益。     

Three-dimensional displacement of the hip joint after triple pelvic osteotomy: A postmortem radiostereometric study

Triple pelvic osteotomy reorients the acetabulum relative to the pelvis in order to improve acetabular coverage of the femoral head in cases of acetabular dysplasia. We undertook a radiostereometric analysis (RSA) on 6 osteotomized cadaver hips to determine the actual three-dimensional reorientation obtained.

The centers of the femoral head were all translated posteriorly between 11 and 41 mm, and distally up to 13 mm. 4 were lateralized up to 8 mm, and 2 were medialized up to 5 mm. All acetabuli rotated anteriorly about the lateral to medial axis (X-axis), and 4 rotated outwards around the distal to proximal axis (Y-axis). The correlations between measurements performed on conventional anteroposterior radiographs and the RSA measurements were poor: variations in the lateral-medial direction ranged from -16 to +6 mm, and in the distal-proximal direction between -10 and +12 mm.

The changes in orientations measured will significantly affect the load across the hip joint, since the dimensions of the pelvis change and the moment arms of the muscles, their lengths and lines of action are changed as well. We conclude that, with the procedures presently performed, the loads across the hip joint are bound to change, and that the reorientation can hardly be checked with conventional radiographs.     

胫骨高位截骨治疗膝骨性关节炎中长期疗效分析

目的 :分析胫骨高位截骨治疗膝骨性关节炎的中长期疗效。方法 :自2001年1月至2005年12月,采用胫骨高位截骨术治疗45例63膝关节内侧间室骨性关节炎患者,男10例(15膝),女35例(48膝);年龄45~64岁,平均(54.76±5.54)岁。术前常规行膝关节负重正侧位X线检查,准确测量股胫角大小,根据术前股胫角决定胫骨外侧截骨量,手术均在硬膜外麻醉下常规行胫骨高位截骨术,大部分行腓骨中段截骨,部分病例行上胫腓关节松解。术后第2天即行功能锻炼,2周开始无负重下床活动,术后8~10周开始负重。术后第2天、8~10周、半年、1年及以后每年1次拍片复查,对全部病例术前、术后3~5年、术后10~14年采用视觉模拟评分(VAS)、美国特种外科医院膝关节评分(HSS)和美国膝关节协会评分(KSS)评价膝关节疼痛、畸形、功能和运动范围。结果 :43例(61膝)进行了10年及以上的随访,全部患者手术切口Ⅰ期愈合,术后8~10周截骨处均达骨性愈合。术后10~14年HSS评分平均76.24±5.27,优27膝,良25膝,可7膝,差2膝。术前与术后3~5年、术前与术后10~14年VAS、HSS、KSS比较有差异,术后3~5年与术后10~14年各项评分无明显差异。结论:胫骨高位截骨治疗膝骨性关节炎(内侧间室关节炎)只要手术指征掌握适当,术后积极锻炼,其中长期疗效满意。