冠心病患者介入治疗前后焦虑抑郁障碍的心理干预与评价

Objective To discuss the effect of psychological intervention of depression in coronary heart disease after percutaneous coronary intervention (PCI). Methods The depression of 105 cases of coronary heart disease after PCI treatment was investigated. One hundred and five patients were randomly divided into intervention group and control group. The patientsin intervention group were treated with psychological intervention before and after PCI. The patients in control group were treated with normal treatment. Results There was not significant difference of incidence of depression an self-rating depression scale score between two groups. The depression in intervention group was less severe than that in control group ( P ＜ 0.01 ). Multivariate analysis showed: education level, the recent negative life events, household income, length of stay and sequelae of catheter intervention had significantly correlated with depression in coronary heart disease. Conclusion Psychological intervention can reduce the ratio of depression in coronary heart disease after PCI.     

冠心病患者介入治疗前后焦虑抑郁障碍的心理干预与评价

Objective To discuss the effect of psychological intervention of depression in coronary heart disease after percutaneous coronary intervention (PCI). Methods The depression of 105 cases of coronary heart disease after PCI treatment was investigated. One hundred and five patients were randomly divided into intervention group and control group. The patientsin intervention group were treated with psychological intervention before and after PCI. The patients in control group were treated with normal treatment. Results There was not significant difference of incidence of depression an self-rating depression scale score between two groups. The depression in intervention group was less severe than that in control group ( P ＜ 0.01 ). Multivariate analysis showed: education level, the recent negative life events, household income, length of stay and sequelae of catheter intervention had significantly correlated with depression in coronary heart disease. Conclusion Psychological intervention can reduce the ratio of depression in coronary heart disease after PCI.     

杯状子宫操作器辅助腹腔镜在全子宫切除术中的应用

Objective To study the superiority and safety of cup-shaped womb manipulator auxiliary peritoneoscope in entire womb excision. Methods 180 cases with hysterectomy were randomly divided into cup-shaped womb manipulator auxiliary peritoneoscope group(treatment group) and tradition into the abdominal group( control group) ,and the amount of bleeding and postoperative complications,and patient recovery were observed in the two groups. Results Compared with the control group, the quality of life of patients with anal exhaust time, average length of staying, postoperative recovery daily time were significantly improved, and there were statistically significant differences between two groups ( P ＜ 0. 05 ). There was no serious complication in the two groups. Conclusion Cup-shaped womb manipulator auxiliary peritoneoscope hysterectomy was a safe and feasible operation,and could relieve harm and improve patients quality of life.     

围术期不同时间应用曲马多对术后镇痛和恶心呕吐的影响

Objective To investigate the analgesic effect and the influence on nausea and vomiting of tramadol during the different periods of perioperation. Methods Fifty-four patients undergoing gynecologic surgery under general anesthesia were randomly divided into three groups according to the time of using tramadol: after operation instantly group, before the end of surgery group and before induction of anesthesia group. All the patients received intravenous patient controlled analgesia(PCA) pump. The vital signs, pain scores and postoperative nausea and vomiting were observed 24 hours after operation. Results There was no significant difference of the vital signs and visual analogue scale (VAS) scores among the three groups( P ＞ 0.05 ). At 8 h after PCA, the number of PCA in before induction of anesthesia group was obviously reduced(P ＜0.05). At 1 h after PCA, the patients in before the end of surgery group experienced the severest nausea and vomiting( P ＜0. 05 ). At 4 h, 8 h and 12 h after PCIA, the patients in after operation instantly group experienced the severest nausea and vomiting ( P ＜ 0.05 ).Conclusion Using tramadol before induction of anesthesia not only has a good analgesic effect, but also decreases the incidence of nausea and vomiting after postoperative analgesia.     

围术期不同时间应用曲马多对术后镇痛和恶心呕吐的影响

Objective To investigate the analgesic effect and the influence on nausea and vomiting of tramadol during the different periods of perioperation. Methods Fifty-four patients undergoing gynecologic surgery under general anesthesia were randomly divided into three groups according to the time of using tramadol: after operation instantly group, before the end of surgery group and before induction of anesthesia group. All the patients received intravenous patient controlled analgesia(PCA) pump. The vital signs, pain scores and postoperative nausea and vomiting were observed 24 hours after operation. Results There was no significant difference of the vital signs and visual analogue scale (VAS) scores among the three groups( P ＞ 0.05 ). At 8 h after PCA, the number of PCA in before induction of anesthesia group was obviously reduced(P ＜0.05). At 1 h after PCA, the patients in before the end of surgery group experienced the severest nausea and vomiting( P ＜0. 05 ). At 4 h, 8 h and 12 h after PCIA, the patients in after operation instantly group experienced the severest nausea and vomiting ( P ＜ 0.05 ).Conclusion Using tramadol before induction of anesthesia not only has a good analgesic effect, but also decreases the incidence of nausea and vomiting after postoperative analgesia.     

冠心病患者冠脉支架植入前后Hs-CRP含量的变化及意义

Objective To detect the concentration of C-reactive protein in patients with coronary heart disease before and after percutaneous coronary intervention (PCI).Methods Forty patients with coronary heart disease that treated with PCI were enrolled.The serum concentration of C-reactive protein (CRP) was analyzed before and after the PCI.Results After PCI,the concentration of CRP were significantly increased compared with that before PCI[(13.91±3.61 ) mg/L versus ( 7.86±3.58 )mg/L,P＜0.01].Conclusion The concentrations of CRP in patients with coronary heart disease were significantly increased after PCI.The level of serum Hs-CRP may reflect inflammatory state of atherosclerosis plaque and it may be important to the prevention and treatment of complications after PCI.     

七氟醚复合丙泊酚在小儿气道异物取出术中的麻醉效果

Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.     

七氟醚复合丙泊酚在小儿气道异物取出术中的麻醉效果

Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.     

七氟醚复合丙泊酚在小儿气道异物取出术中的麻醉效果

Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.     

七氟醚复合丙泊酚在小儿气道异物取出术中的麻醉效果

Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.     

"简化"和常规冠状动脉造影术的对比研究

目的通过对应用“简化”冠状动脉造影术和常规冠状动脉造影术检查患者临床资料的对比观察，评价“简化”冠状动脉造影术临床应用的可行性、实用性及安全性。方法2003年1月～2006年6月在我院行冠状动脉造影检查患者980例，随机分为常规冠状动脉造影组494例（用三联三通，简称常规组，常规投照体位为7～9个）。“简化”冠状动脉造影组486例（未用三联三通，投照体位为4～6个，简称“简化”组），比较两组X线照射时间、手术操作时间、手术成功率、冠状动脉并发症（冠状动脉痉挛、导管嵌顿阻塞冠脉开121、室颤1、材料费用、造影剂剂量、肾功能。结果两组患者X线照射时间分别为（7．38±3．08）min和（4．32±2．95）min（P〈0.05）；手术操作时间分别为（19．49±9．19）min和（12．13±8．25）min（P〈0.01）；手术成功率均为100％（P〉0.05）；冠状动脉并发症分别为4例和3例（P〉0．05）；材料费用分别为（1465．30±188．78）元和（1188．52±163．66）元（P〈0．01）；造影剂剂量为（42．5±6．3）ml和（32．9±6．1）ml（P〈0.01），无一例造影剂肾病发生。结论“简化”冠状动脉造影术和常规冠状动脉造影术一样安全、有效，且更简单实用，比常规组节省费用、减少X线照射时间、造影剂量和手术操作时间，值得在基层医院开展。     

冠状动脉痉挛的血管造影和血管内超声研究

目的:探讨痉挛的冠状动脉血管造影(CAG)和血管内超声(IVUS)的病变特征.方法:选择临床上具有心前区不适或疼痛但CAG无显著狭窄的患者进行马来酸麦角新碱试验,根据CAG有无冠状动脉痉挛将患者分为痉挛组及无痉挛组.通过CAG及IVUS探讨痉挛血管的病理特征.IVUS检查包括参考段血管面积(RA)、最小血管内膜腔面积(MLA)、斑块面积(PA)、斑块体积(PV)及斑块的性状和重构指数,斑块的性状分为软斑块和硬斑块(包括纤维斑块、钙化斑块和混合斑块).结果:成功诱发冠状动脉痉挛20例,痉挛组及无痉挛组患者间性别、吸烟及高脂血症有明显差异(P＜0.05),但两组冠状动脉的狭窄程度及斑块的大小无明显差异(P＞0.05);痉挛组CAG示轻、中度局限性狭窄伴血管边缘不光滑,IVUS示偏心性纤维斑块,伴血管正性重构.结论:冠状动脉痉挛血管病变常表现为血管边缘不光滑,呈偏心性、稳定性的纤维性斑块,伴血管正性重构.     

老年急性冠状动脉综合征的急诊介入治疗研究

目的研究与分析老年急性冠状动脉综合征的急诊介入治疗的疗效。方法本文选择了80例老年急性冠状动脉综合征患者进行研究,将这些患者按其意愿分为两组,每组40例,PTCA组患者采用急诊介入的方法进行治疗,对照组则采用常规的药物治疗,之后对比研究这两种治疗方法的疗效及两组患者血凝指标。结果通过对比两组患者的病死率、并发症以及冠状动脉残余狭窄等方面的情况,发现PTCA组患者优于对照组,两组之间存在差异,具有统计学意义(P<0.05)。结论采用急诊介入的治疗方法治疗老年急性冠状动脉综合征的疗效与采用常规治疗方法相比,效果明显,值得在急诊科推广应用。     

冠状动脉痉挛的血管造影和血管内超声研究

目的:探讨痉挛的冠状动脉血管造影(CAG)和血管内超声(IVUS)的病变特征.方法:选择临床上具有心前区不适或疼痛但CAG无显著狭窄的患者进行马来酸麦角新碱试验,根据CAG有无冠状动脉痉挛将患者分为痉挛组及无痉挛组.通过CAG及IVUS探讨痉挛血管的病理特征.IVUS检查包括参考段血管面积(RA)、最小血管内膜腔面积(MLA)、斑块面积(PA)、斑块体积(PV)及斑块的性状和重构指数,斑块的性状分为软斑块和硬斑块(包括纤维斑块、钙化斑块和混合斑块).结果:成功诱发冠状动脉痉挛20例,痉挛组及无痉挛组患者间性别、吸烟及高脂血症有明显差异(P＜0.05),但两组冠状动脉的狭窄程度及斑块的大小无明显差异(P＞0.05);痉挛组CAG示轻、中度局限性狭窄伴血管边缘不光滑,IVUS示偏心性纤维斑块,伴血管正性重构.结论:冠状动脉痉挛血管病变常表现为血管边缘不光滑,呈偏心性、稳定性的纤维性斑块,伴血管正性重构.